Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Tribulus 625 mg Ingredients & Drug Interactions

by BIOVEA

Tribulus 625 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tribulus 625 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tribulus 625 mg is a dietary supplement by BIOVEA with 2 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus Terrestris extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tribulus 625 mg by BIOVEA

Ask about any prescription or over-the-counter medication and we check it for interactions with Tribulus 625 mg by BIOVEA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tribulus 625 mg by BIOVEA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Tribulus Blend” is a proprietary blend — the label gives one combined amount (625 mg) without saying how much of each component you get.

This capsule contains 2 active ingredients, both forms of tribulus terrestris extract. Tribulus is a plant used traditionally to support sexual function and athletic performance.

The product also includes inactive ingredients—hydroxypropyl methylcellulose, silica, vegetable magnesium stearate, and microcrystalline cellulose—which are the capsule and binding materials.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Tribulus's overall clinical evidence instead.

Moderate

Some clinical evidence supports Tribulus for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sexual dysfunction — rated "Possibly Effective" (Natural Medicines).

Tribulus is rated possibly effective for sexual dysfunction based on the evidence we have. For athletic performance, the research suggests it's possibly ineffective.

For benign prostatic hyperplasia (enlarged prostate), the evidence isn't strong enough to rate it one way or the other. Keep in mind that the long-term safety data is limited, so what we know comes mostly from shorter-term studies.

The evidence, ingredient by ingredient Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is generally well tolerated in the short term for most healthy adults, but long-term safety data are thin. Rare serious side effects have been reported in the literature, including liver and kidney injury, seizures, and a painful prolonged erection.

Gastrointestinal upset—stomach pain, cramping, nausea, vomiting, diarrhea, or constipation—can occur, though one study found these complaints occurred at similar rates in people taking tribulus and those on placebo. Avoid this product during pregnancy because it may affect hormones and safety hasn't been established.

Also avoid it while breastfeeding due to lack of reliable safety data. Talk with your doctor or pharmacist about whether it's right for your situation.

Side effects, ingredient by ingredient Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Tribulus 625 mg, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives) or diabetes medications—both Moderate risk—or if you take lithium (Moderate risk). These are the drug types with documented interactions that matter most.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Tribulus may help with sexual dysfunction based on available evidence, but it's not proven for athletic performance and evidence is unclear for prostate health. If you take blood pressure medications, diabetes drugs, or lithium, you need to check with your doctor or pharmacist before starting—this supplement can affect how those drugs work.

It's generally well tolerated short-term, but long-term safety isn't well studied, and it's not safe in pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tribulus 625 mg, straight from the product label.

Brand BIOVEA
Barcode (UPC) 818423024264
Net contents 100 Vegetarian Capsules
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 249138
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tribulus 625 mg by BIOVEA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
100
UPC/BARCODE
818423024264
IngredientAmount% DV
Tribulus Terrestris extract0 NP--
Proprietary Tribulus Blend625 mg--
Tribulus Terrestris0 NP--

Other ingredients: Hydroxypropyl Methylcellulose, Silica, Vegetable Magnesium Stearate, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

GMP Compliant

Formulation

VG Vegan

General Statements

Premium quality guaranteed since 2001. BIOVEA is committed to product quality to support you and your family's wellness goals. Because we feel so strongly about the quality, potency and purity of our products, we 100% guarantee your satisfaction with every purchase.

Guaranteed premium quality

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Take one 1 or two 2 capsules daily, preferably with morning and evening meals.

Precautions

Warning: If you are pregnant or lactating, consult a healthcare professional before using this product.

Keep out of reach of children.

Do not use this product if the safety seal on the bottle is broken.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Formula

Herb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tribulus 625 mg by BIOVEA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tribulus 625 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tribulus 625 mg by BIOVEA

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Tribulus Blend

625 mg per serving

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Silica, Vegetable Magnesium Stearate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tribulus 625 mg by BIOVEA Drug Interactions

Want to check YOUR meds against Tribulus 625 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

Tribulus Terrestris extract 259

Individual Drug Interactions

The ingredients in Tribulus 625 mg interact with 259 drugs. Click any drug to see the details.

1 of the 2 ingredients in Tribulus 625 mg interact with drugs. Each result below shows which ingredient is responsible. Tribulus Terrestris extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Tribulus 625 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus Terrestris extract3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus Terrestris extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tribulus 625 mg, from the product label.

BIOVEA

See all BIOVEA products
Name
BIOVEA
Street Address
9160 E. Bahia Dr.
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
www.biovea.com
Pharmacist Counseling Corner

Tribulus 625 mg by BIOVEA: Common Questions

Does Tribulus 625 mg by BIOVEA interact with any medications?
Yes. Based on its ingredients, Tribulus 625 mg has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tribulus 625 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tribulus actually work for sexual dysfunction?
It's rated possibly effective based on available research, which means there's some evidence supporting it, but it's not proven. Results vary from person to person, and more studies would help clarify how well it really works.
Can I take this if I'm pregnant or breastfeeding?
No—the safety data advise against it during pregnancy because tribulus may affect hormones and safety isn't established. While breastfeeding, there isn't enough reliable information either, so it's best to avoid it. Talk with your doctor or pharmacist about alternatives.
What side effects should I watch for?
Most people tolerate it well, but stomach upset—cramping, nausea, vomiting, diarrhea—can happen. Rare serious effects like liver or kidney injury and seizures have been reported. Stop taking it and contact your doctor right away if you experience severe symptoms or unusual pain or weakness.
Is tribulus safe to take long-term?
Short-term use seems generally well tolerated in healthy adults, but long-term safety data are limited. There isn't enough information to say how safe it is over months or years, so this is something to discuss with your pharmacist or doctor.
Will this help me build muscle or improve athletic performance?
The evidence suggests tribulus is possibly ineffective for athletic performance, so it's unlikely to give you a boost in that area. It's primarily used for sexual function, not for sports performance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tribulus 625 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tribulus 625 mg label
Go deeper

The Full Monographs Behind Tribulus 625 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Tribulus 625 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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