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Dietary supplement

Tribulus Terrestris Capsules 400 mg Ingredients & Drug Interactions

by Organic Aura

Tribulus Terrestris Capsules 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tribulus Terrestris Capsules 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tribulus Terrestris Capsules 400 mg is a dietary supplement by Organic Aura with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Puncture Vine powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tribulus Terrestris Capsules 400 mg by Organic Aura

Ask about any prescription or over-the-counter medication and we check it for interactions with Tribulus Terrestris Capsules 400 mg by Organic Aura — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tribulus Terrestris Capsules 400 mg by Organic Aura

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains one active ingredient: organic Puncture Vine powder at 400 mg per serving. Puncture Vine (Tribulus terrestris) is a plant used traditionally to support sexual function and athletic performance.

The product is made from 100% pure organic Puncture Vine Powder with no other listed fillers or additives.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Tribulus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: libido, stamina, testosterone, heart and fertility support.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Male infertility, Athletic performance, Exercise-induced muscle damage, Hypertension — and 4 related terms.
  • The closest evidence on file: Tribulus is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction, Erectile dysfunction (ED), Hypercholesterolemia, Hypertension, and more.

Tribulus shows possibly effective evidence for sexual dysfunction — the primary use for this product. However, for athletic performance, the evidence suggests it's possibly ineffective.

For benign prostatic hyperplasia (enlarged prostate), we don't have enough reliable evidence to rate it either way.

The evidence, ingredient by ingredient Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is generally well tolerated in the short term by healthy adults, but long-term safety data are limited and quality varies between products. Gastrointestinal side effects like stomach pain, nausea, and diarrhea can occur, though in one study these rates matched placebo.

Rare serious effects — including liver and kidney injury and seizures — have been reported. Avoid this product during pregnancy because it may affect hormones and its safety in pregnancy is not established.

Also avoid it while breastfeeding due to lack of reliable safety information.

Side effects, ingredient by ingredient Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take blood pressure medications, diabetes medications, or lithium. Tribulus can lower blood pressure and blood sugar, and may increase lithium levels — all Moderate-severity interactions that could affect how your medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Tribulus may help with sexual dysfunction, but it's not proven for athletic performance. If you take blood pressure meds, diabetes meds, or lithium, check with your doctor or pharmacist before starting — the interactions can be significant.

Long-term safety isn't well established, so use short-term and talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tribulus Terrestris Capsules 400 mg, straight from the product label.

Brand Organic Aura
Barcode (UPC) 731236219316
Net contents 100 Veg Capsule(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 243198
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tribulus Terrestris Capsules 400 mg by Organic Aura, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
731236219316
IngredientAmount% DV
organic Puncture Vine powder400 mg--

Other ingredients: 100% pure organic Puncture Vine Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Tribulus Terrestris Tribulus Terrestris component called steroidal saponins present in Tribulus supports heart and circulatory health. It is commonly known to increase fertility for both men and women. Tribulus naturally increases testosterone and enhance libido levels and increase your sex drive.

Organic Aura Fenugreek powder is 100% pure and fresh, ground using the top quality Fenugreek seeds from a single source, grown by traditional organic farming in the highly enriched valleys of India.

Made with certified Tribulus Terrestris Powder.

Raw organic whole food Actual Tribulus Terrestris

Formulation

Supports libido and stamina Supports to produce testosterone Supports heart and circulatory health Supports endurance and performance

Produce of Organic Agriculture from India

100% Certified Organic

Natural Testosterone and Libido Support

100% Natural

No soy, yeast, corn, sugar, starch, egg, milk, preservatives, artificial colors or flavors.

Organic

Made with Non-GMO ingredients

Raw

Gluten-free

Precautions

Keep out of the reach of children

Do not use if safety seal is broken or missing

Caution: For adults only, if you are pregnant, nursing, taking any medications or have any medical condition, consult you doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Keep in cool, dry place.

FDA Statement of Identity

Herbal Dietary Supplement

General Statements

ECO

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, take 1 capsule 2 times a day with a glass of water or as directed by your healthcare professional

Seals/Symbols

Good Manufacturing Practice GMP Quality Product

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tribulus Terrestris Capsules 400 mg by Organic Aura label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tribulus Terrestris Capsules 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tribulus Terrestris Capsules 400 mg by Organic Aura

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Organic Puncture Vine powder

Interacts with
259 drugs
400 mg per serving

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Organic Puncture Vine powder monograph & interactions

Other (inactive) ingredients: 100% pure organic Puncture Vine Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tribulus Terrestris Capsules 400 mg by Organic Aura Drug Interactions

Want to check YOUR meds against Tribulus Terrestris Capsules 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

organic Puncture Vine powder 259

Individual Drug Interactions

The ingredients in Tribulus Terrestris Capsules 400 mg interact with 259 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tribulus Terrestris Capsules 400 mg interact with drugs. Each result below shows which ingredient is responsible. organic Puncture Vine powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Tribulus Terrestris Capsules 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Puncture Vine powder3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
organic Puncture Vine powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tribulus Terrestris Capsules 400 mg, from the product label.

Organic Aura

See all Organic Aura products
Name
Organic Aura International An Organic Ayurveda Company
Street Address
2924 Kendale Dr.
City
Toledo
State
OH
ZipCode
43606
Web Address
www.OrganicAuraNaturals.com
Pharmacist Counseling Corner

Tribulus Terrestris Capsules 400 mg by Organic Aura: Common Questions

Does Tribulus Terrestris Capsules 400 mg by Organic Aura interact with any medications?
Yes. Based on its ingredients, Tribulus Terrestris Capsules 400 mg has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tribulus Terrestris Capsules 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tribulus really help with sexual performance?
The evidence says it's possibly effective for sexual dysfunction, meaning there's some clinical support but it's not conclusive. Results vary person to person, and you may want to give it a few weeks to see if it works for you.
Can I take this while I'm on blood pressure or diabetes medication?
Not without checking first. Tribulus can lower blood pressure and blood sugar on its own, so combining it with those medications risks dropping them too low. Talk to your doctor or pharmacist — they may need to monitor you or adjust your dose.
Is tribulus safe to take long-term?
Short-term use in healthy adults is generally well tolerated, but we don't have solid long-term safety data. Quality also varies between products. Use it for a few weeks and discuss any concerns with your healthcare provider before continuing.
Can I take this if I'm pregnant or breastfeeding?
No — avoid it during pregnancy because it may affect hormones and safety isn't established. Also avoid it while breastfeeding due to lack of reliable safety information. Talk with your doctor about safe alternatives.
What's in these capsules besides tribulus?
Just the active ingredient: 100% pure organic Puncture Vine powder. There are no other fillers or additives listed.
What side effects might I experience?
Mild gastrointestinal complaints like stomach pain, nausea, diarrhea, or constipation can occur, though in one study these rates matched placebo. Rare serious effects like liver or kidney injury and seizures have been reported in case reports.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tribulus Terrestris Capsules 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tribulus Terrestris Capsules 400 mg label
Go deeper

The Full Monographs Behind Tribulus Terrestris Capsules 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph →
Sources

Sources & How We Checked

Tribulus Terrestris Capsules 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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