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Dietary supplement

Triple Strength Omega Complex Lemon Natural Flavor Ingredients & Drug Interactions

by GNC

Triple Strength Omega Complex Lemon Natural Flavor label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Triple Strength Omega Complex Lemon Natural Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Triple Strength Omega Complex Lemon Natural Flavor is a dietary supplement by GNC with 6 active ingredients. Its ingredients are commonly taken for heart health, healthy cooking fat, skin moisturizing.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oleic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Triple Strength Omega Complex Lemon Natural Flavor by GNC

Ask about any prescription or over-the-counter medication and we check it for interactions with Triple Strength Omega Complex Lemon Natural Flavor by GNC — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Triple Strength Omega Complex Lemon Natural Flavor by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Total Omega-3s” is listed as a grouped ingredient — the label gives one combined amount (1,395 mg) without saying how much of each component you get.

This product contains 6 active omega-3 and omega fatty acid ingredients: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), gamma-linolenic acid, oleic acid, and alpha-linolenic acid, plus a blend labeled Total Omega-3s. They come from fish body oil, borage seed oil, and flax seed oil, with gelatin capsules and inactive ingredients like glycerin, caramel color, and mixed tocopherols for freshness.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports heart, brain, skin, eye and joint health.
  • We looked for evidence on: Coronary heart disease (CHD), Hypertension, Hypercholesterolemia, Stroke, Cognitive function, Vision health — and 1 related terms.
  • The strongest evidence on file: Oleic Acid is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Oleic Acid is rated "Possibly Effective" for Hypercholesterolemia.
  • Also on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Stroke.

Oleic acid — one of the active ingredients — is rated possibly effective for high cholesterol and coronary heart disease based on the evidence we hold. We don't have effectiveness ratings in our data for the other omega-3 and omega fatty acids in this product, so we can't speak to whether they work for any particular condition.

The evidence, ingredient by ingredient Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid is generally recognized as safe at the amounts naturally found in foods like olive oil. However, concentrated supplement doses of oleic acid haven't been well studied, and safety data is limited in pregnancy and during breastfeeding.

If you're pregnant, nursing, or planning to become pregnant, talk with your pharmacist or doctor before starting this product.

Side effects, ingredient by ingredient Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (medication for type 2 diabetes or high blood sugar), double-check them below before you use this product — oleic acid may boost their effect and lower your blood sugar more than intended. We couldn't check the other omega ingredients in this product for interactions, so your pharmacist can help flag any concerns specific to your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a multi-ingredient omega supplement where we could only check one ingredient for drug interactions — oleic acid — which may strengthen the effect of diabetes medication. If you take any prescription medication, especially for blood sugar control, check it with the tool below before you start.

Otherwise, a conversation with your pharmacist is a good idea.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Triple Strength Omega Complex Lemon Natural Flavor, straight from the product label.

Brand GNC
Barcode (UPC) 048107177935
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 309901
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Triple Strength Omega Complex Lemon Natural Flavor by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Softgel Capsule(s)
Maximum serving Sizes:
3 Softgel Capsule(s)
Servings per container
30
UPC/BARCODE
048107177935
IngredientAmount% DV
Calories30 Calorie(s)--
Eicosapentaenoic Acid647 mg--
Docosahexaenoic Acid253 mg--
Total Fat3.5 Gram(s)4%
Gamma-Linolenic Acid180 mg--
Oleic Acid150 mg--
Alpha-Linolenic Acid375 mg--
Total Omega-3s1395 mg--
Other Omega-3s120 mg--

Other ingredients: Fish Body Oil, Borage Seed Oil, Flax seed Oil, Bovine Gelatin, Glycerin, Olive Fruit Oil, Water, Purified, Caramel color, Mixed Tocopherols, Natural Flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Contains: Fish (anchovy, mackerel, sardine, smelt, whiting, pollock, salmon, tuna, cod or a combination thereof), sesame and sulfites.

Storage

Store in a cool, dry place.

Formulation

Purified to reduce contaminants such as heavy metals, dioxins and PCBs

From wild ocean fish

Supports heart, brain, skin, eye & joint health

No artificial flavors, gluten free, no milk. GF Gluten free

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

1725 mg of omega-3-6-9s from fish & plant sources

Lemon natural flavor with other natural flavors

Seals/Symbols

High-Quality Purified

FDA Statement of Identity

Omega 3-6-9 Supplement

General Statements

For more information: 1-888-462-2548 30-Day supply

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take three softgel capsules daily with food.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Triple Strength Omega Complex Lemon Natural Flavor by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Triple Strength Omega Complex Lemon Natural Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Triple Strength Omega Complex Lemon Natural Flavor by GNC

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Softgel Capsule(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gamma-Linolenic Acid

180 mg per serving

Oleic Acid

Interacts with
86 drugs
150 mg per serving

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it...

Oleic Acid monograph & interactions

Total Omega-3s

1395 mg per serving
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid
  • › Alpha-Linolenic Acid
  • › Other Omega-3s

Other (inactive) ingredients: Fish Body Oil, Borage Seed Oil, Flax seed Oil, Bovine Gelatin, Glycerin, Olive Fruit Oil, Water, Purified, Caramel color, Mixed Tocopherols, Natural Flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Triple Strength Omega Complex Lemon Natural Flavor by GNC Drug Interactions

Want to check YOUR meds against Triple Strength Omega Complex Lemon Natural Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Oleic Acid 86

Individual Drug Interactions

The ingredients in Triple Strength Omega Complex Lemon Natural Flavor interact with 86 drugs. Click any drug to see the details.

1 of the 6 ingredients in Triple Strength Omega Complex Lemon Natural Flavor interact with drugs. Each result below shows which ingredient is responsible. Oleic Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in Triple Strength Omega Complex Lemon Natural Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oleic Acid1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, oleic acid might increase the effects of antidiabetes drugs. Preliminary clinical research in patients with type 2 diabetes taking oral hypoglycemic drugs shows that eating a diet rich in oleic acid from olive oil decreases fasting blood glucose levels when compared to eating a diet rich in linoleic acid from sunflower oil. It is unknown if taking oleic acid supplements would have this effect or if this change is clinically significant. Until more is known, use caution. Dose adjustment may be necessary. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence B
Oleic Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Triple Strength Omega Complex Lemon Natural Flavor, from the product label.

GNC

See all GNC products
Name
GNC Holdings, LLC
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Pharmacist Counseling Corner

Triple Strength Omega Complex Lemon Natural Flavor by GNC: Common Questions

Does Triple Strength Omega Complex Lemon Natural Flavor by GNC interact with any medications?
Yes. Based on its ingredients, Triple Strength Omega Complex Lemon Natural Flavor has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Triple Strength Omega Complex Lemon Natural Flavor contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this omega supplement actually help with cholesterol or heart health?
Oleic acid in this product is rated possibly effective for high cholesterol and coronary heart disease. We don't have effectiveness data for the other omega-3 ingredients, so we can't say whether they work for those conditions or any others.
Is it safe to take this while I'm pregnant or breastfeeding?
Oleic acid at food levels is generally safe, but concentrated supplement doses haven't been well studied in pregnancy or lactation. Talk with your doctor or pharmacist for personalized advice before starting.
What are EPA and DHA, and what are they supposed to do?
EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are omega-3 fatty acids from fish oil. We don't hold effectiveness data for them in our system, so we can't tell you what conditions this product targets based on those ingredients.
Can this interact with my diabetes medication?
Yes — oleic acid may increase the effects of antidiabetes drugs and lower your blood sugar further. If you take any diabetes medication, use the checker on this page to search your exact prescriptions, and talk with your pharmacist about whether you need a dose adjustment.
Are there any fillers or artificial ingredients I should know about?
The inactive ingredients include fish body oil, borage seed oil, flax seed oil, gelatin capsules, glycerin, olive oil, caramel color, and mixed tocopherols. No artificial sweeteners or colors are listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Triple Strength Omega Complex Lemon Natural Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Triple Strength Omega Complex Lemon Natural Flavor label
Go deeper

The Full Monographs Behind Triple Strength Omega Complex Lemon Natural Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

Triple Strength Omega Complex Lemon Natural Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 19 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. Gillingham, L. G., Gustafson, J. A., Han, S. Y., Jassal, D. S., and Jones, P. J. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr 2011;105(3):417-427. PubMed
  3. Jones PJ, Senanayake VK, Pu S, Jenkins DJ, Connelly PW, Lamarche B, Couture P, Charest A, Baril-Gravel L, West SG, Liu X, Fleming JA, McCrea CE, Kris-Etherton PM. DHA-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiova
  4. Cater, N. B., Heller, H. J., and Denke, M. A. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am.J Clin.Nutr PubMed
  5. Mozaffarian D, Clarke R. Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils. Eur J Clin Nutr. 2009;63(Suppl 2):S22-33. PubMed
  6. Cao Y, Hou L, Wang W. Dietary total fat and fatty acids intake, serum fatty acids and risk of breast cancer: A meta-analysis of prospective cohort studies. Int J Cancer. 2016;138(8):1894-904. doi: 10.1002/ijc.29938. PubMed
  7. FDA completes review of qualified health claim petition for oleic acid and the risk of coronary heart disease. November 2018. Available at: www.fda.gov/Food/NewsEvents/ConstituentUpdates/ucm624758.htm. Accessed January 25, 2019.
  8. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity. 2016;24(11):2261-2268. PubMed
  9. Bowen KJ, Kris-Etherton PM, West SG, et al. Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity. J Nutr. 2019;149(3 PubMed
  10. Steffen BT, Duprez D, Szklo M, Guan W, Tsai MY. Circulating oleic acid levels are related to greater risks of cardiovascular events and all-cause mortality: The Multi-Ethnic Study of Atherosclerosis. J Clin Lipidol. 2018;12(6):1404-1412. PubMed
  11. Banim PJ, Luben R, Khaw KT, Hart AR. Dietary oleic acid is inversely associated with pancreatic cancer - Data from food diaries in a cohort study. Pancreatology. 2018;18(6):655-660. PubMed
  12. Morin SJ, Gaziano JM, Djoussé L. Relation between plasma phospholipid oleic acid and risk of heart failure. Eur J Nutr. 2018;57(8):2937-2942. PubMed
  13. Samieri C, Féart C, Proust-Lima C, et al. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study. Neurology. 2011;77(5):418-25. PubMed
  14. Compher CW, Kinosian BP, Rubesin SE, Ratcliffe SJ, Metz DC. Energy absorption is reduced with oleic acid supplements in human short bowel syndrome. JPEN J Parenter Enteral Nutr. 2009;33(1):102-8. PubMed
  15. Ben Fradj MK, Ouanes Y, Hadj-Taieb S, et al. Decreased oleic acid and marine n?-?3 polyunsaturated fatty acids in Tunisian patients with urothelial bladder cancer. Nutr Cancer. 2018;70(7):1043-1050.
  16. de Silva PS, Luben R, Shrestha SS, Khaw KT, Hart AR. Dietary arachidonic and oleic acid intake in ulcerative colitis etiology: a prospective cohort study using 7-day food diaries. Eur J Gastroenterol Hepatol. 2014;26(1):11-8. PubMed
  17. Higashi K, Shige H, Ito T, et al. Effect of a low-fat diet enriched with oleic acid on postprandial lipemia in patients with type 2 diabetes mellitus. Lipids. 2001;36(1):1-6. PubMed
  18. Lin HC, van Citters GW, Heimer F, Bonorris G. Slowing of gastrointestinal transit by oleic acid: a preliminary report of a novel, nutrient-based treatment in humans. Dig Dis Sci. 2001;46(2):223-9. PubMed
  19. Li D, Tong Y, Li Y. Associations between dietary oleic acid and linoleic acid and depressive symptoms in perimenopausal women: The Study of Women's Health Across the Nation. Nutrition. 2020 Mar;71:110602. PubMed

See these in context on the Oleic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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