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Dietary supplement

TrueAsta Ingredients & Drug Interactions

by NatureCity

TrueAsta label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking TrueAsta against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

TrueAsta is a dietary supplement by NatureCity with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against TrueAsta by NatureCity

Ask about any prescription or over-the-counter medication and we check it for interactions with TrueAsta by NatureCity — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of TrueAsta by NatureCity

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TrueAsta is a single-ingredient supplement: astaxanthin (marketed here as AstaReal), a carotenoid — a natural pigment with antioxidant properties. The capsule itself is filled with extra virgin olive oil and contains gelatin, glycerin, and water as inactive ingredients that help deliver and stabilize the active ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for astaxanthin isn't established yet in the data we hold. Studies have looked at it for age-related cognitive decline, macular degeneration (AMD), skin aging, Alzheimer disease, athletic performance, and carpal tunnel syndrome, but the results so far aren't reliable enough to rate how well it actually works for any of those uses.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are mild: abdominal pain, diarrhea, and red fecal color (a harmless discoloration from the supplement itself).

At standard doses around 6 mg daily, a small number of people reported increased bowel movements or red stool; at much higher doses (40 mg daily), rare cases of severe stomach pain occurred. During pregnancy, the safety data aren't sufficient to know either way — we advise against it based on the information available.

The same applies to breastfeeding. Talk with your doctor or pharmacist about whether this supplement is right for you if you're pregnant or nursing.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take TrueAsta, check whether you're on medications metabolized by CYP3A4 or CYP2B6 enzymes — astaxanthin may theoretically lower their levels in your blood. Statins, blood pressure drugs, immunosuppressants, certain antidepressants, and antiretrovirals are common examples.

Use the medication search tool on this page to verify your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

TrueAsta may interest you if you're exploring antioxidant support, but the evidence for its specific benefits isn't solid yet. The real caution here is for anyone on medications broken down by your liver (CYP3A4 or CYP2B6 drugs) — check with your pharmacist first.

Pregnant or breastfeeding? Skip this one unless your doctor gives you the green light.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about TrueAsta, straight from the product label.

Brand NatureCity
Barcode (UPC) 859003007680
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283366
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for TrueAsta by NatureCity, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
859003007680
IngredientAmount% DV
AstaReal6 mg--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Each soft gel is one (1) serving. Take one (1) to two (2) servings per day or as directed by your healthcare practitioner.

Precautions

Keep out of reach of children

Do not use if seal is broken or missing

Storage

Store in a cool dry place

Formula

AstaReal The Natural Astaxanthin of Choice

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Soy free Non GMO Gluten free

Natural astaxanthin

Seals/Symbols

Blended & packaged in the USA

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

AstaReal is a registered trademark of Fuji Chemical Industries Co., Ltd.

General Statements

To re-order call toll-free: 1-800-593-2563

BPA free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

TrueAsta by NatureCity label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

TrueAsta label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in TrueAsta by NatureCity

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

AstaReal

Interacts with
671 drugs
6 mg per serving Form: Astaxanthin, Natural

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

TrueAsta by NatureCity Drug Interactions

Want to check YOUR meds against TrueAsta?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaReal 671

Individual Drug Interactions

The ingredients in TrueAsta interact with 671 drugs. Click any drug to see the details.

1 of the 1 ingredient in TrueAsta interact with drugs. Each result below shows which ingredient is responsible. AstaReal

Each ingredient & the kinds of drugs it affects

For each ingredient in TrueAsta with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaReal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for TrueAsta, from the product label.

NatureCity

See all NatureCity products
Name
NatureCity
Street Address
990 S. Rogers Circle
City
Boca Raton
State
FL
ZipCode
33487
Phone Number
1-800-593-2563
Web Address
www.naturecity.com
Pharmacist Counseling Corner

TrueAsta by NatureCity: Common Questions

Does TrueAsta by NatureCity interact with any medications?
Yes. Based on its ingredients, TrueAsta has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
TrueAsta contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is astaxanthin?
Astaxanthin is a carotenoid — a natural pigment with antioxidant properties. In TrueAsta, it comes in the form called AstaReal, delivered in a softgel capsule with olive oil to help your body absorb it.
Can I take TrueAsta if I'm pregnant or breastfeeding?
The safety data aren't enough to know either way, so we advise against it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about your personal situation before taking it.
What side effects might I experience?
Most people tolerate it well. The most common side effects are mild: abdominal pain, diarrhea, and red fecal color (a harmless discoloration from the supplement). At very high doses, severe stomach pain has been reported rarely.
Does astaxanthin actually work for anti-aging or memory?
We don't have reliable evidence yet. Studies have looked at it for skin aging, memory, macular degeneration, and other age-related concerns, but the results aren't solid enough to say how well it works.
Is there anything else in the capsule besides astaxanthin?
Yes — the softgel contains extra virgin olive oil, gelatin, glycerin, and water. These are inactive ingredients that help deliver and stabilize the astaxanthin, not active components.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if TrueAsta is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

TrueAsta label
Go deeper

The Full Monographs Behind TrueAsta’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

TrueAsta's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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