Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Tulsi Ashwagandha Ingredients & Drug Interactions

by Organic India

Tulsi Ashwagandha label
See full label image
Other (e.g. Tea Bag) Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tulsi Ashwagandha against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tulsi Ashwagandha is a dietary supplement by Organic India with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,430 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Ashwagandha, organic Tulsi (Holy Basil) Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tulsi Ashwagandha by Organic India

Ask about any prescription or over-the-counter medication and we check it for interactions with Tulsi Ashwagandha by Organic India — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tulsi Ashwagandha by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Organic Blend” is a proprietary blend — the label gives one combined amount (2 Gram(s)) without saying how much of each component you get.
  • “organic Tulsi (Holy Basil) Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Tulsi Ashwagandha contains three active ingredients: organic ashwagandha, holy basil (also called East Indian basil or tulsi), and an organic proprietary blend. Ashwagandha is an herb traditionally used to help with stress, anxiety, and sleep.

Holy basil is another adaptogenic herb — it's meant to help your body manage stress. Together, they're designed to work on relaxation and calm.

The product also contains inactive ingredients, including organic fruit flavors, which are just there for taste.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: stress relief, mood uplift, and immune support.
  • We looked for evidence on: Stress, Anxiety, Generalized anxiety disorder (GAD), Depression, Psychological well-being, Fatigue — and 4 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD), Insomnia, Stress.
  • Also on file: Ashwagandha is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chemotherapy-related fatigue, Depression.

The data we have shows ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder (GAD). For holy basil, the evidence isn't established yet — we hold insufficient data to rate it for anxiety, asthma, headache, respiratory infections, dental plaque, or diabetes.

Ashwagandha's track record on sleep and anxiety is the stronger one in this blend.

The evidence, ingredient by ingredient Ashwagandha Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ashwagandha and holy basil are generally well tolerated in the short term for healthy adults, though long-term safety data are limited. The most common side effects are mild — ashwagandha may cause diarrhea, nausea, or stomach upset, and holy basil may cause loose stools or nausea, though these don't happen often at typical doses.

Rarely, ashwagandha has been linked to serious liver problems, drowsiness, headache, and in one case report, bleeding in the brain. You should avoid this product during pregnancy — both ingredients carry safety concerns, and ashwagandha was traditionally thought to risk miscarriage.

Don't use it while breastfeeding either, because there isn't enough safety information.

Side effects, ingredient by ingredient Ashwagandha Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Ashwagandha, Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,431 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check if you're on any immunosuppressants, anticoagulants or antiplatelet drugs (blood thinners), sedatives or anti-anxiety medications (including benzodiazepines and barbiturates), blood pressure medications, diabetes medications, thyroid hormone, or any medication that can affect the liver. Worst severity first, ashwagandha's effect on your immune system and blood pressure are Moderate concerns, as are the bleeding and blood sugar risks from both ashwagandha and holy basil.

Ashwagandha also has a Minor effect on drugs metabolized by CYP1A2 enzymes.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Tulsi Ashwagandha may help with anxiety and sleep, but it interacts with quite a few medication types — especially blood thinners, diabetes drugs, blood pressure medications, sedatives, and immunosuppressants. If you take any prescription medication, check your list against our tool before starting.

Avoid it if you're pregnant or breastfeeding, and talk to your pharmacist if you have any liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tulsi Ashwagandha, straight from the product label.

Brand Organic India
Barcode (UPC) 801541514861
Net contents 18 Infusion Bag(s); 1.27 oz.; 36 Gram(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 222784
Product type Botanical
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tulsi Ashwagandha by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Infusion Bag(s)
Maximum serving Sizes:
1 Infusion Bag(s)
Servings per container
18
UPC/BARCODE
801541514861
IngredientAmount% DV
organic Ashwagandha0 NP--
Holy Basil0 NP--
East Indian Basil0 NP--
Proprietary Organic Blend2 Gram(s)--
organic Tulsi (Holy Basil) Blend0 NP--

Other ingredients: organic Indian Fruit flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Revered in India as "The Queen of Herbs," Tulsi (Holy Basil) is an adaptogenic herb that has been used for more than 5,000 years to: Aid in stress relief & uplift mood Support the immune system Support the natural detoxification process

Renowned adaptogens, Ashwagandha and Tulsi, accented with fruit essence to uplift your spirits and enhance overall vitality.

Halal Mumbai India Halal Committee Jamiat Ulama-E-Maharashtra Registration No.: 0854 OU

Suggested/Recommended/Usage/Directions

Brewing instructions: Use 1 infusion bag per cup of just boiled water. Cover and steep for 5-10 min.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

New

Individually wrapped for freshness

Product of India For export Mfg. Lic. No. A-2755

At the heart of Organic India is our commitment to be a living embodiment of love & consciousness in action. Small family farmers Empowering small family farmers in India to cultivate regenerative, organic farmland Revitalizing communities through fair wages, education, healthcare, access to clean water & job skills training Regenerative Agriculture Regenerating soil health & fertility Improving water retention & sequestering carbon Restoring vibrant health to the environment Healthy conscious living Celebrating the interconnectedness of life Cultivating the health of our planet, our farmers & you Pictured on the front is one of our beloved farmers or a family member.

Organic India is committed to responsible packaging. This carton is made from 100% recycled paperboard, with a minimum of 30% post-consumer content. Our infusion bags are made from unbleached, biodegradable fiber. Please support our environment by recycling this package.

Formulation

Stress Relieving & Balancing

Caffeine free

Non GMO

Vegan Vegetarian

Gluten free

Product processed as per COS standards and Certified Organic by Aditi Organic Certifications Pvt. Ltd. Accreditation No. COR01204046

FDA Statement of Identity

Herbal supplement

Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation

Halal Mumbai India Halal Committee Jamiat Ulama-E-Maharashtra Registration No.: 0854 OU

Precautions

To enjoy while pregnant or nursing, consult a physician before use.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tulsi Ashwagandha by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tulsi Ashwagandha label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tulsi Ashwagandha by Organic India

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Infusion Bag(s) Dosage formOther (e.g. Tea Bag) Servings per container18 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Organic Blend

2 Gram(s) per serving

Other (inactive) ingredients: Organic Indian Fruit flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tulsi Ashwagandha by Organic India Drug Interactions

Want to check YOUR meds against Tulsi Ashwagandha?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,430Drugs
1,002 Moderate 428 Minor

Ingredients driving the most interactions

organic Ashwagandha 1,372
organic Tulsi (Holy Basil) Blend 212

Individual Drug Interactions

The ingredients in Tulsi Ashwagandha interact with 1,430 drugs. Click any drug to see the details.

2 of the 2 ingredients in Tulsi Ashwagandha interact with drugs. Each result below shows which ingredient is responsible. organic Ashwagandha organic Tulsi (Holy Basil) Blend

Each ingredient & the kinds of drugs it affects

For each ingredient in Tulsi Ashwagandha with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Ashwagandha10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
organic Ashwagandha full monograph & interactions

organic Tulsi (Holy Basil) Blend3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
organic Tulsi (Holy Basil) Blend full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tulsi Ashwagandha, from the product label.

Organic India

See all Organic India products
Name
Organic India Pvt. Ltd.
Street Address
Factory: C-5/10, Agro Park Phase -II UPSIDC Industrial Area, Kursi Road
City
Barabanki
State
U.P.
ZipCode
225302
Pharmacist Counseling Corner

Tulsi Ashwagandha by Organic India: Common Questions

Does Tulsi Ashwagandha by Organic India interact with any medications?
Yes. Based on its ingredients, Tulsi Ashwagandha has a known interaction with 1,430 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tulsi Ashwagandha contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant or breastfeeding?
No. Ashwagandha was traditionally thought to risk miscarriage, and holy basil has animal safety concerns — both should be avoided in pregnancy. There isn't enough safety data to use it while breastfeeding either. Talk to your doctor or midwife about what's safe for you.
What are the most common side effects?
Ashwagandha may cause diarrhea, nausea, stomach upset, or vomiting, though these are uncommon at normal doses. Holy basil may cause loose stools or nausea. Both are generally well tolerated, but long-term safety data are limited.
Does ashwagandha really help with sleep and anxiety?
According to the data we hold, ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. For holy basil, the evidence isn't established yet — we don't have enough data to rate it either way.
Is this safe if I have liver problems?
You should be careful. While ashwagandha is generally well tolerated, there are rare case reports of serious liver damage linked to it. If you have liver disease or take medications that can stress your liver, talk to your pharmacist before using this product.
What's the difference between ashwagandha and holy basil in this blend?
Both are adaptogens meant to help with stress and anxiety. Ashwagandha has stronger evidence for sleep and anxiety. Holy basil is traditionally used for similar purposes, but we don't have enough data yet to rate how well it works for those conditions.
Will this make me drowsy?
Ashwagandha has been reported to cause drowsiness, so it's possible this product could make you sleepy — which might actually be helpful if you're taking it for sleep. Just be careful if you're also on sedative medications or driving.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tulsi Ashwagandha label
Go deeper

The Full Monographs Behind Tulsi Ashwagandha’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Tulsi Ashwagandha's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 40 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
  9. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
  10. Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
  11. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
  12. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
  13. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
  14. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
  15. Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
  16. Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
  17. Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
  18. Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
  19. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
  20. Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
  21. Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
  22. Ajgaonkar A, Jain M, Debnath K. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus 2022;14(10):e30787. PubMed
  23. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  24. Lubarska M, Halasinski P, Hryhorowicz S, et al. Liver Dangers of Herbal Products: A Case Report of Ashwagandha-Induced Liver Injury. Int J Environ Res Public Health 2023;20(5):3921. PubMed
  25. Tóth M, Benedek AE, Longerich T, Seitz HK. Ashwagandha-induced acute liver injury: A case report. Clin Case Rep 2023;11(3):e7078.
  26. Bokan G, Glamocanin T, Mavija Z, et al. Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause. Pharmaceuticals (Basel) 2023;16(8):1129. PubMed
  27. Patel PA, Sanborn E, Then R, Williams DM. Recurrent Reversible Cerebral Vasoconstriction Syndrome: A Report of Two Cases. Cureus 2023;15(8):e42992. PubMed
  28. Majeed M, Nagabhushanam K, Murali A, Vishwanathan DT, Mamidala RV, Mundkur L. A Standardized Withania somniferra (Linn.) Root Extract with Piperine Alleviates the Symptoms of Anxiety and Depression by Increasing Serotonin Levels: A Double-Blind, Randomize
  29. Philips CA, Valsan A, Theruvath AH, et al. Ashwagandha-induced liver injury-A case series from India and literature review. Hepatol Commun 2023;7(10):e0270. PubMed
  30. Hayashi M, Hamada H, Azuma SI, Hayashi K. Painless Thyroiditis by Withania somnifera (Ashwagandha). Cureus 2024;16(3):e55352. PubMed
  31. Vazirani S, Kothari A, Fujimoto J, Gomez M. Supplements Are Not a Synonym for Safe: Suspected Liver Injury From Ashwagandha. Fed Pract 2023;40(9):315-319. PubMed
  32. Patel M, Newell R, Hillier M, Ramalingam R. Herbal remedies as a potential cause of hypoadrenalism. Br J Hosp Med (Lond) 2024;85(6):1-4. PubMed

See these in context on the Ashwagandha monograph →

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

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