Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Tulsi-Holy Basil Positive Stress Response Ingredients & Drug Interactions

by Organic India

Tulsi-Holy Basil Positive Stress Response label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tulsi-Holy Basil Positive Stress Response against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tulsi-Holy Basil Positive Stress Response is a dietary supplement by Organic India with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Holy Basil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tulsi-Holy Basil Positive Stress Response by Organic India

Ask about any prescription or over-the-counter medication and we check it for interactions with Tulsi-Holy Basil Positive Stress Response by Organic India — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tulsi-Holy Basil Positive Stress Response by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Proprietary Organic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

This product contains 2 active ingredients, both forms of holy basil — listed as a Proprietary Organic Blend and as East Indian Holy Basil. Holy basil is a plant traditionally used for stress and relaxation.

The capsule also contains pullulan, an inactive ingredient used as a capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Holy Basil's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support immunity, stress response and detoxification.
  • We looked for evidence on: Stress, Generalized anxiety disorder (GAD), Respiratory tract infections, immune function, detoxification.
  • The closest evidence on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Holy Basil is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections, Stress.

We don't have strong evidence that holy basil works for stress, anxiety, asthma, headaches, respiratory infections, dental plaque, or diabetes. The data we hold rates all of those uses as having insufficient reliable evidence.

That doesn't mean it doesn't work — it means larger, higher-quality studies haven't been done yet. If you're thinking about this for a specific health concern, talk with us about what the research actually shows.

The evidence, ingredient by ingredient Holy Basil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Holy basil is generally well tolerated in the short term, though we don't have high-quality long-term safety data. The most common side effects from oral use are loose stools and nausea — a small number of people in trials reported these.

The safety data advises against this product during pregnancy and while breastfeeding, since animal research raised concerns and human safety isn't established.

Side effects, ingredient by ingredient Holy Basil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Holy Basil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with us if you're on blood thinners (like warfarin or clopidogrel), diabetes medications, or pentobarbital. These are the medication types with documented moderate-level interactions with holy basil.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is for people interested in trying holy basil for stress support who don't take blood thinners, diabetes medications, or barbiturates. If you're pregnant, breastfeeding, or on any prescription, check with us first.

We can help you see whether it's right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tulsi-Holy Basil Positive Stress Response, straight from the product label.

Brand Organic India
Barcode (UPC) 851469000793
Net contents 90 Vegetarian Cap(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 327601
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tulsi-Holy Basil Positive Stress Response by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
851469000793
IngredientAmount% DV
Proprietary Organic Blend0 NP--
Holy Basil600 mg--
East Indian Holy Basil300 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Love & consciousness in action: Whole herb solutions grown by small family farmers using regenerative organic agriculture.

Visit www.info.fairtrade.net

Mfg. Lic. No. A-2755

Formulation

Vegan Vegetarian

Gluten free

Positive Stress Response

Certified Organic by Control Union-CU 801983. Product produced and processed according to NPOP standard of India & USDA-NOP

Non GMO Project Verified nongmoproject.org

Product of India For export to USA only

Formula

Holy Basil: Fairtrade certified and sourced from Fairtrade Producers. Total 100%, excluding the capsule.

Tulsi has traditionally been used to support immunity, stress response and detoxification.

Halal Mumbai India Halal Committee Registration No. 0854

OU Kosher

Suggested/Recommended/Usage/Directions

Suggested use: 3 caps once daily with food and water.

Precautions

Do not use if pregnant or nursing without consulting a physician.

Warning: Reproductive harm - www.P65Warnings.ca.gov

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org Fairtrade Control Union Certified NPOP/NAB/0010 Halal Mumbai India Halal Committee Registration No. 0854 OU Kosher Certified B Corporation

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tulsi-Holy Basil Positive Stress Response by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tulsi-Holy Basil Positive Stress Response label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tulsi-Holy Basil Positive Stress Response by Organic India

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Organic Blend

0 NP per serving

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tulsi-Holy Basil Positive Stress Response by Organic India Drug Interactions

Want to check YOUR meds against Tulsi-Holy Basil Positive Stress Response?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Holy Basil 212

Individual Drug Interactions

The ingredients in Tulsi-Holy Basil Positive Stress Response interact with 212 drugs. Click any drug to see the details.

1 of the 2 ingredients in Tulsi-Holy Basil Positive Stress Response interact with drugs. Each result below shows which ingredient is responsible. Holy Basil

Each ingredient & the kinds of drugs it affects

For each ingredient in Tulsi-Holy Basil Positive Stress Response with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Holy Basil3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tulsi-Holy Basil Positive Stress Response, from the product label.

Organic India

See all Organic India products
Name
Organic India USA
City
Boulder
State
CO
ZipCode
80301
Phone Number
1-888-550-8332
Web Address
OrganicIndiaUSA.com
Pharmacist Counseling Corner

Tulsi-Holy Basil Positive Stress Response by Organic India: Common Questions

Does Tulsi-Holy Basil Positive Stress Response by Organic India interact with any medications?
Yes. Based on its ingredients, Tulsi-Holy Basil Positive Stress Response has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tulsi-Holy Basil Positive Stress Response contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against it during pregnancy because animal research raised concerns and human safety isn't established. The same goes for breastfeeding — there isn't enough reliable safety information. Talk with your doctor or pharmacist about what might be right for you.
What are the most common side effects?
Loose stools and nausea. In one clinical study, a small number of participants taking holy basil capsules reported these. Overall, it's well tolerated, but we don't have a lot of long-term safety data.
Does this actually work for stress and anxiety?
The evidence we hold rates it as insufficient — we don't have reliable studies showing it works for stress, anxiety, or the other uses listed on the label. That doesn't mean it doesn't help, just that we need better research to know for sure.
Is this safe to use long-term?
We know it's generally well tolerated short-term in adults, but high-quality long-term safety data are limited. If you're thinking of taking it regularly, it's worth checking in with us about what the data shows.
What is holy basil, and why is it in this product?
Holy basil is a plant used traditionally for relaxation and stress support. This product contains two forms of it — a proprietary blend and East Indian holy basil — both meant to support a positive stress response.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tulsi-Holy Basil Positive Stress Response is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tulsi-Holy Basil Positive Stress Response label
Go deeper

The Full Monographs Behind Tulsi-Holy Basil Positive Stress Response’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph →
Sources

Sources & How We Checked

Tulsi-Holy Basil Positive Stress Response's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Holy Basil 8 references
  1. Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
  2. Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
  3. Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
  4. Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
  5. Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
  6. Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
  7. Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
  8. Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.

See these in context on the Holy Basil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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