Urinary Bladder Support Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Urinary Bladder Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Urinary Bladder Support is a dietary supplement by Herbal Terra with 4 active ingredients. Its ingredients are commonly taken for urinary tract complaints, mild bladder irritation, increasing urine flow (diuretic).Based on those ingredients, 2,143 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow Leaf Extract, Dry, Uva Ursi Herb Extract, Corn Silk, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Urinary Bladder Support by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Urinary Bladder Support by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Urinary Bladder Support by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Urinary Bladder Support contains four active ingredients. Three are herbal extracts: couch grass root, uva ursi (bearberry leaf), and marshmallow leaf — all traditional botanicals used for urinary tract health.
The fourth is corn silk, a diuretic plant extract. The product also contains inactive ingredients: alcohol, water, and glycerin, which form the liquid base.
Does it work?
Leans against
The evidence for these ingredients is limited. Uva ursi is rated possibly ineffective for urinary tract infections and has insufficient reliable evidence for bronchitis and benign prostate enlargement.
Marshmallow leaf and corn silk have insufficient reliable evidence for their use in any of the conditions listed. Couch grass effectiveness data aren't on file.
If you're taking this product for urinary tract support, know that proof of benefit is thin in the data we hold.
How safe is it?
Well-documented data
Uva ursi is generally well tolerated at low doses for short periods, but carries a caution: at very high doses (20 grams of dried herb or more), it can cause serious effects like convulsions and delirium — and 30 grams or more may be fatal. Common lower-dose side effects include nausea, vomiting, diarrhea, and stomach upset.
Couch grass, marshmallow leaf, and corn silk are generally well tolerated short-term, though human safety data are limited for all three. Uva ursi is not safe in pregnancy and should be avoided while breastfeeding; marshmallow leaf and couch grass should also be avoided in pregnancy and breastfeeding due to insufficient safety information.
Corn silk may be possibly safe while breastfeeding, but should be avoided in pregnancy. Do not use any of these ingredients long-term without professional guidance.
Meds to double-check
Moderate interaction found
Before taking this product, double-check if you use any blood pressure medications, diabetes drugs, blood thinners (especially warfarin), diuretics, corticosteroids, or lithium. Uva ursi may also affect medications metabolized by your liver (CYP2C19 and CYP3A4 substrates) — ask your pharmacist if any of yours fit that category.
These are Moderate-severity concerns, and the search tool below will help you confirm your specific medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines herbal diuretics and urinary tract remedies with weak evidence of benefit and several drug interactions to watch for. If you take any medications — especially for blood pressure, diabetes, blood clotting, potassium balance, or lithium — talk to your pharmacist before starting.
Pregnant and breastfeeding individuals should avoid it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Urinary Bladder Support, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7439500734741 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 325476 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Urinary Bladder Support by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 983 mg | -- |
| Couch Root Extract, Dry | 0 NP | -- |
| Uva Ursi Herb Extract | 0 NP | -- |
| Marshmallow Leaf Extract, Dry | 0 NP | -- |
| Corn Silk, Dry | 0 NP | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Organic alcohol
FDA Statement of Identity
Herbal Supplement
General Statements
Extraction rate: about 1/3-4 (up to 333 mg of dry material per 1 ml of extract).
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Urinary Bladder Support by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Urinary Bladder Support by Herbal Terra
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Urinary Bladder Support by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Urinary Bladder Support by Herbal Terra contains four active ingredients, and three of them have documented interactions with medications.
Uva ursi is the ingredient with the most serious concerns — it may slow how your body metabolizes certain drugs (CYP2C19 and CYP3A4 substrates) and theoretically could raise lithium levels, both Moderate severity interactions. It may also interfere with drugs that acidify your urine, which could reduce uva ursi's own effectiveness in the urinary tract.
Read the full breakdown — every affected drug type, severity by severity
Corn silk carries Moderate interactions with blood pressure medications (antihypertensive drugs), diabetes medications, blood thinners like warfarin, diuretics (water pills), and corticosteroids — chiefly because it lowers blood pressure, affects blood sugar, contains vitamin K, and increases potassium loss in the urine. Marshmallow leaf has Moderate risk with lithium and Minor risk with oral medications generally and with blood thinners (anticoagulants/antiplatelets), mainly because it may have diuretic properties and its mucilage can interfere with drug absorption.
Couch grass root extract was not checked — we hold no data on its interactions. Altogether, these interactions span 2,124 individual medications.
Check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Urinary Bladder Support?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Urinary Bladder Support interact with 2,143 drugs. Click any drug to see the details.
3 of the 4 ingredients in Urinary Bladder Support interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Leaf Extract, Dry Uva Ursi Herb Extract Corn Silk, Dry
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Urinary Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Abemaciclib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Abiraterone interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Abiraterone Acetate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Uva Ursi Herb Extract + Abrocitinib interactionMarshmallow Leaf Extract, DryOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acalabrutinib interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Corn Silk, Dry + Acarbose interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Corn Silk, DryAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Corn Silk, Dry + Acebutolol interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acebutolol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Aspirin interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Aspirin, Caffeine interactionMarshmallow Leaf Extract, DryAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Butalbital interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Butalbital, Caffeine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Butalbital, Codeine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Codeine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Isometheptene interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Urinary Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Caffeine, Pyrilamine interactionCorn Silk, DryDiuretic Drugs Moderate
Interaction Summary
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Read the full Corn Silk, Dry + Acetaminophen, Caffeine, Pyrilamine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractGlucuronidated Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Urinary Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Uva Ursi Herb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Uva Ursi Herb Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionMarshmallow Leaf Extract, DryOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow Leaf Extract, Dry + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Urinary Bladder Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Marshmallow Leaf Extract, Dry
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
Uva Ursi Herb Extract
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
Corn Silk, Dry
Antidiabetes Drugs
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.
Antihypertensive Drugs
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.
Corticosteroids
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.
Diuretic Drugs
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.
Warfarin (Coumadin)
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.
Brand information
Manufacturer and brand details for Urinary Bladder Support, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Urinary Bladder Support by Herbal Terra: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Urinary Bladder Support’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Couch Grass
Couch grass is a common lawn weed whose rhizome has long been used in traditional European herbal medicine, mainly for urinary and bladder complaints. High-quality human studies are lacking,...
Read the full Couch Grass monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph → Herb & supplement monographMarshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph → Herb & supplement monographCorn Silk
Interacts with 290 drugsCorn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...
Read the full Corn Silk monograph →Sources & How We Checked
Urinary Bladder Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Marshmallow 5 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.
Corn Silk 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
- Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC