Interactions on record — worth a quick check against your medications. Based on 3 of 10 ingredients. Check your meds →
Dietary supplement

VigorCare For Men Ingredients & Drug Interactions

by Himalaya

VigorCare For Men label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking VigorCare For Men against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

VigorCare For Men is a dietary supplement by Himalaya with 10 active ingredients. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 521 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Saffron, Tribulus extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against VigorCare For Men by Himalaya

Ask about any prescription or over-the-counter medication and we check it for interactions with VigorCare For Men by Himalaya — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of VigorCare For Men by Himalaya

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (600 mg) without saying how much of each component you get.

VigorCare For Men contains 10 ingredients, organized around a proprietary herbal blend. The active components include tribulus extract and plain tribulus, saffron and saffron extract, almond and almond extract, blepharis, hygrophilia, and hygrophilia extract.

The only inactive ingredient listed is plant-based cellulose, which serves as a capsule material. The tribulus and saffron are the primary actives linked to the product's intended effects on sexual function.

Almond is included for its nutritional profile, while blepharis and hygrophilia are traditional herbal ingredients whose roles are less well documented in modern research.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: sexual performance and energetic intimacy.
  • We looked for evidence on: Erectile dysfunction (ED), Male infertility, Sexual dysfunction, Premature ejaculation, Antidepressant-induced sexual dysfunction, libido — and 3 related terms.
  • The strongest evidence on file: Tribulus is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Premature ejaculation, Male infertility.
  • Also on file: Saffron is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction, Erectile dysfunction (ED), Male infertility.

Tribulus has possibly effective evidence for sexual dysfunction. For athletic performance, the evidence leans toward possibly ineffective.

There isn't enough reliable data to rate it for benign prostatic hyperplasia (BPH). Saffron and saffron extract show possibly effective evidence for chemotherapy-induced peripheral neuropathy (nerve pain from cancer treatment) and Alzheimer disease.

Almond has insufficient evidence for the health conditions listed in our data. The effectiveness of blepharis and hygrophilia isn't established in the information we hold.

The evidence, ingredient by ingredient Tribulus Saffron Sweet Almond

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is often well tolerated in the short term in healthy adults, but long-term and quality safety data are limited. Gastrointestinal complaints like nausea, diarrhea, and vomiting can occur, though in one study these rates were similar to placebo.

Rare serious effects including liver and kidney injury and seizures have been reported. Avoid tribulus during pregnancy because it may affect hormones and safety isn't established.

Also avoid it while breastfeeding due to lack of safety information. Saffron extract is generally well tolerated but carries rare risk of anaphylaxis.

Common side effects include gastrointestinal upset, nausea, and sedation. High doses can be toxic.

Avoid saffron in supplement amounts during pregnancy because it may stimulate the uterus. There isn't enough reliable safety information for breastfeeding, so it's best to avoid supplement amounts.

Almond is safe as a food in pregnancy and breastfeeding if you're not allergic, but tree-nut allergy is a serious concern — almonds are classified as a major food allergen in the U.S.

Side effects, ingredient by ingredient Tribulus Saffron Sweet Almond

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Tribulus, Saffron.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 521 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking VigorCare For Men, check with your doctor or pharmacist if you take blood pressure medications (antihypertensive drugs), diabetes medications, lithium, sedatives or sleep aids (CNS depressants), or caffeine supplements. All of these carry Moderate-severity interaction risks with the tribulus and saffron in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

VigorCare For Men may help with sexual dysfunction if you don't take blood pressure or diabetes medications, mood stabilizers, CNS depressants, or caffeine supplements. If you're on any prescription medications, use the search tool on this page to check them before you start.

Talk with your doctor or pharmacist about whether this product makes sense for you and your current regimen — especially if you're pregnant, breastfeeding, or have a tree-nut allergy.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about VigorCare For Men, straight from the product label.

Brand Himalaya
Barcode (UPC) 605069015028
Net contents 60 Vegetarian Capsules
Market status On market
Date entered into DSLD Nov 20, 2017
DSLD ID 80235
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Male (18-50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for VigorCare For Men by Himalaya, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
605069015028
IngredientAmount% DV
Proprietary Herbal Blend600 mg--
Tribulus extract0 NP--
Tribulus0 NP--
Saffron0 NP--
Saffron extract0 NP--
Almond0 NP--
Almond extract0 NP--
Blepharis0 NP--
Hygrophilia0 NP--
Hygrophilia extract0 NP--
Blepharis extract0 NP--

Other ingredients: Plant Based Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Ayurveda teaches that intimacy is a sacred act and describes it as a critical factor for a healthy, emotionally satisfying relationship. The ancient text suggest the sacredness with which a society approaches intimacy mirrors the health of the society at large.

With this in mind, Ayurveda identified important plants that can evoke a healthy, satisfying desire that honors the role of intimacy.

cGMP

Happiness through wellness

Crafting traditional medicines based on Ayurveda, a 5,000 year old science that believes the journey back to wholeness begins with nurturing the capacity for joy.

Trusting the gifts of nature and the irreplaceable relationship between the plant and its native soil for consistent healing properties.

Contributing to the wellness of the earth by teaching our family of farmers to grow native plants sustainably on their land and reduce the demand on the local environment.

Building communities by advocating women in farming, protecting fair prices, providing maternal health, sponsoring clinical services and offering school wellness programs.

Believing that if wellness is the path to happiness, we must contribute to the wellness of all things. Wellness of people, wellness of the environment, wellness of our communities.

Family owned for more than 85 years

Since 1930

Boosts libido & performance Enhances desire & energy

Happiness through wellness

1 month supply

Mfg. Lic. No. AUS-83

Product of India

Questions? Please call 1-800-869-4640 or visit www.himalayausa.com

Formula

VigorCare for men combines those herbs to promote sexual performance and energetic intimacy.

Featured herbs on front: Almonds (seeds), Blepharis (aerial parts) & Saffron (flower)

Contains: Almond

Formulation

Gluten free

Vegan friendly

Wheat, corn, soy, dairy

No ingredients of animal origin

Non-GMO Gluten free

General

HUS-5033347

Seals/Symbols

Non GMO Project Verified nongmoproject.org

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Adults take 2 capsules daily, one hour before bedtime.

Precautions

Contains: Almond

Caution: As with any supplement, consult a healthcare practitioner before use if you are taking medication, have a medical condition or are planning any medical procedure.

Discontinue use and consult a healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

VigorCare For Men by Himalaya label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

VigorCare For Men label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in VigorCare For Men by Himalaya

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

600 mg per serving

Other (inactive) ingredients: Plant Based Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

VigorCare For Men by Himalaya Drug Interactions

Want to check YOUR meds against VigorCare For Men?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
521Drugs
521 Moderate

Ingredients driving the most interactions

Saffron 521
Tribulus extract 259

Individual Drug Interactions

The ingredients in VigorCare For Men interact with 521 drugs. Click any drug to see the details.

2 of the 10 ingredients in VigorCare For Men interact with drugs. Each result below shows which ingredient is responsible. Saffron Tribulus extract

Each ingredient & the kinds of drugs it affects

For each ingredient in VigorCare For Men with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Saffron4 drug types · 521 drugs

Antidiabetes Drugs

Theoretically, concomitant use of saffron with antidiabetes drugs might increase the risk of hypoglycemia.
Some clinical research shows that taking saffron extract reduces fasting levels of glucose when used in addition to hypoglycemic agents. However, saffron powder itself has not been shown to reduce fasting glucose levels.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of saffron with antihypertensive drugs might have additive effects.
Animal and human research suggests that saffron extract can decrease blood pressure.

Likelihood Possible Evidence D
Caffeine

Theoretically, saffron might inhibit the metabolism of caffeine.
A small clinical study suggests that taking saffron powder 300 mg in 150 mL water daily for 5 days and then taking caffeine 200 mg seems to reduce caffeine metabolite levels in the saliva and urine in males, but not females. Theoretically, this may be due to the inhibition of cytochrome P450 1A2 by saffron.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, concomitant use of saffron and CNS depressants might have additive sedative effects.
Clinical research shows that taking saffron extract 60 mg orally daily for 26 weeks can cause drowsiness and sedation. Animal research suggests that adding saffron to hexobarbital further increases sleeping and slows motor activity.

Likelihood Possible Evidence D
Saffron full monograph & interactions

Tribulus extract3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for VigorCare For Men, from the product label.

Himalaya

See all Himalaya products
Name
The Himalaya Drug Company
City
Makali
State
Bangalore
ZipCode
562 162
Pharmacist Counseling Corner

VigorCare For Men by Himalaya: Common Questions

Does VigorCare For Men by Himalaya interact with any medications?
Yes. Based on its ingredients, VigorCare For Men has a known interaction with 521 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
VigorCare For Men contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take VigorCare For Men if I'm on blood pressure medication?
Both tribulus and saffron in this product can lower blood pressure. If you're already taking a blood pressure medication, adding this product could push your pressure too low. You need to check with your doctor or pharmacist before combining them — they may need to monitor you or adjust your dose.
Can I take this if I have diabetes or take diabetes medication?
Tribulus and saffron can both lower blood sugar levels. If you're taking diabetes medication, this product could increase your risk of low blood sugar (hypoglycemia). Talk with your doctor or pharmacist before starting it.
What are the most common side effects I might notice?
The most common complaints from the herbal ingredients are gastrointestinal — nausea, abdominal pain, diarrhea, and vomiting. Saffron may also cause drowsiness. These happen in a small number of people, and in one study the rates were similar to placebo. Allergic reactions to almond are possible if you have a tree-nut allergy.
Does tribulus actually help with sexual dysfunction?
Tribulus shows possibly effective evidence for sexual dysfunction, meaning there's some research backing it, but the evidence isn't definitive. Results vary person to person, and long-term safety data are limited.
Is it okay to take this if I'm pregnant or breastfeeding?
No. Tribulus should be avoided — it may affect hormones and safety isn't established. Saffron at supplement doses should also be avoided in pregnancy because it may stimulate the uterus, and there isn't enough safety data for breastfeeding. Almond as food is safe if you're not allergic, but this product is a supplement, not a food.
What if I take caffeine or energy drinks?
Saffron may slow how your body clears caffeine from your system, which could make caffeine's effects stronger. If you regularly consume caffeine, mention that to your doctor or pharmacist before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if VigorCare For Men is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

VigorCare For Men label
Go deeper

The Full Monographs Behind VigorCare For Men’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph → Herb & supplement monograph

Saffron

Interacts with 521 drugs

Saffron is a costly spice that has shown promise in early studies for mild-to-moderate depression and some mood and PMS symptoms, but most research uses small trials, so results are not defi...

Read the full Saffron monograph → Herb & supplement monograph

Sweet Almond

Sweet almonds are a nutritious tree nut rich in healthy fats, fiber, protein, vitamin E, and minerals, and they are generally safe and healthy to eat as part of a balanced diet. Almond oil i...

Read the full Sweet Almond monograph →
Sources

Sources & How We Checked

VigorCare For Men's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 36 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Saffron 22 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Feo F, Martinez J, Martinez A, et al. Occupational allergy in saffron workers. Allergy 1997;52:633-41. PubMed
  5. Wuthrich B, Schmid-Grendelmeyer P, Lundberg M. Anaphylaxis to saffron. Allergy 1997;52:476-7. PubMed
  6. Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. Phytother Res 2005;19:148-51.
  7. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasth
  8. Fatehi, M., Rashidabady, T., and Fatehi-Hassanabad, Z. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. J Ethnopharmacol. 2003; PubMed
  9. Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine. 2008;15(12):1032-1037. PubMed
  10. Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. Phytother.Res 12-9-2009;
  11. Zhang, Y., Shoyama, Y., Sugiura, M., and Saito, H. Effects of Crocus sativus L. on the ethanol-induced impairment of passive avoidance performances in mice. Biol.Pharm Bull. 1994;17(2):217-221. PubMed
  12. Wuthrich, B., Schmid-Grendelmeyer, P., and Lundberg, M. Anaphylaxis to saffron. Allergy 1997;52(4):476-477. PubMed
  13. Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi A. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and plac
  14. Kashani L, Eslatmanesh S, Saedi N, Niroomand N, Ebrahimi M, Hosseinian M, Foroughifar T, Salimi S, Akhondzadeh S. Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial. Ph PubMed
  15. Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res. 2011 Dec;25(12):1801-5. PubMed
  16. Mazidi M, Shemshian M, Mousavi SH, Norouzy A, Kermani T, Moghiman T, Sadeghi A, Mokhber N, Ghayour-Mobarhan M, Ferns GA. A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. J C
  17. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment. Int J Impo PubMed
  18. Talaei A, Hassanpour Moghadam M, Sajadi Tabassi SA, Mohajeri SA. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. J Affect Disord. 2 PubMed
  19. Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Effects of cinnamon, cardamom, saffron, and ginger consumption on markers of glycemic control, lipid profile, oxidative stress, and inflammation in type 2 diabetes. Rev Diabet Stud. 2014 Fall-Winter;11(3-4
  20. Begas E, Bounitsi M, Kilindris T, et al. Effects of short-term saffron (Crocus sativus L.) intake on the in vivo activities of xenobiotic metabolizing enzymes in healthy volunteers. Food Chem Toxicol. 2019;130:32-43. PubMed
  21. Moravej Aleali A, Amani R, Shahbazian H, Namjooyan F, Latifi SM, Cheraghian B. The effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabet
  22. Abbaszadeh-Mashkani S, Hoque SS, Banafshe HR, Ghaderi A. The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment. Phytother Res. 2021; PubMed

See these in context on the Saffron monograph →

Sweet Almond 4 references
  1. Motaharifard MS, Effatpanah M, Karimi M, et al. Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial. Complement Ther Clin Pract. 2019;36:170-175. PubMed
  2. Simon D, Nobbe S, Nägeli M, et al. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Dermatol Ther. 2018;31(6):e12692. PubMed
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
  4. Salama M, Tebben PJ, Al Nofal A. An infant developing hypercalcemia and hypophosphatemia due to the use of exclusively almond milk. J Pediatr Endocrinol Metab 2024;37(4):375-379. PubMed

See these in context on the Sweet Almond monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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