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Dietary supplement

Vitamin A 10,000 IU Ingredients & Drug Interactions

by Country Life

Softgel Capsule Category: Vitamin
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Vitamin A 10,000 IU is a dietary supplement by Country Life with 1 active ingredient. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 387 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vitamin A 10,000 IU by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: vitamin A, at 10,000 IU per softgel. The inactive ingredients are gelatin, glycerin, purified water, and medium chain triglycerides—standard capsule materials and carriers.

This product is a straightforward, single-ingredient supplement.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports immune, skin, and eye health.
  • We looked for evidence on: Acne, Aging skin, Atopic dermatitis (eczema), Cataracts, Corneal abrasion, Night vision — and 4 related terms.
  • The strongest evidence on file: Vitamin A is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Vitamin A is rated "Possibly Effective" for Night vision, Retinitis pigmentosa.
  • Also on file: Vitamin A is rated "Possibly Ineffective" for Melanoma.

Vitamin A is effective for treating vitamin A deficiency. The evidence supporting it for other uses—oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia—is rated possibly effective, meaning the research is suggestive but not yet conclusive.

The evidence, ingredient by ingredient Vitamin A

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A is generally well tolerated at recommended doses, but it's fat-soluble, so it builds up in your body over time and can become toxic at high doses. High-dose vitamin A—particularly in the retinol form—carries a risk of birth defects and should be avoided in pregnancy.

The safety data advises against high-dose use unless a clinician directs it. At very high doses, vitamin A can cause serious effects like pseudotumor cerebri (swelling inside the skull), liver damage, headache, vision changes, and in rare cases, coma.

Chronic overuse causes dry, itchy, peeling skin, hair loss, and brittle nails.

Side effects, ingredient by ingredient Vitamin A

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 388 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this if you use retinoids (like tretinoin or isotretinoin for acne), warfarin or other blood thinners, tetracycline antibiotics, or drugs that stress the liver. Major interactions exist with retinoids; Moderate interactions affect blood thinners, tetracyclines, and hepatotoxic drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is a good fit if you're correcting a vitamin A deficiency and aren't taking retinoid medications or blood thinners. If you take warfarin, tetracycline antibiotics, or other liver-sensitive drugs, or if you're pregnant, check with your pharmacist first.

At the 10,000 IU dose per softgel, stick to recommended intake levels and don't exceed them—vitamin A toxicity is real with chronic overuse.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin A 10,000 IU, straight from the product label.

Brand Country Life
Barcode (UPC) 015794055419
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Apr 22, 2016
DSLD ID 59220
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin A 10,000 IU by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
015794055419
IngredientAmount% DV
Vitamin A10000 IU200%

Other ingredients: Gelatin, Glycerin, purified Water, Capsule Shell, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Vitamin A is an important essential vitamin that supports immune, skin, and eye health. As it is derived from fish liver oil, it is third party tested for heavy metals such as mercury to endure purity and safety.

Established 1971

~ Supports immune skin and eye health

Our PLEDGE of INTEGRITY AUTHENTICITY - CLEANLINESS - FRESHNESS CONSISTENCY - ACCURACY

YES RECYCLABLE PACKAGING YES MANUFACTURING SUPPORTS WIND POWER

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Yes Certified Gluten-Free by GFCO.ORG

Certified Gluten-Free

No Yeast, Corn or Wheat No Soy or Milk No Salt or Sugar No Preservatives No Artificial Color No Magnesium Stearate No GMOs

Seals/Symbols

Third Party Tested

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) softgel daily with food.

Precautions

As a reminder, discuss supplements and medications that you take with your healthcare provider.

Contains fish (cod).

Caution: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

If any adverse reactions occur, stop taking the product and consult your doctor.

Not intended for people under the age of 18.

Not recommended for people who regularly consume liver. Do not exceed 10,000 I.U. of vitamin A per day.

Pregnant women and women of childbearing age, do not exceed 8,000 I.U. of vitamin A per day.

Keep out of reach of children.

Do not accept if seal is broken.

Formula

Contains fish (cod).

100% bovine gelatin, BSE-free

Storage

Store between 59(0)-86(0) F.

General

01L14NL

See for yourself

Vitamin A 10,000 IU by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vitamin A 10,000 IU by Country Life

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Vitamin A

Interacts with
387 drugs
10000 IU per serving Form: Cod Liver Oil, Retinyl Palmitate

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water, Capsule Shell, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin A 10,000 IU by Country Life Drug Interactions

Want to check YOUR meds against Vitamin A 10,000 IU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
387Drugs
9 Major 378 Moderate

Ingredients driving the most interactions

Vitamin A 387

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin A 10,000 IU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Vitamin A 10,000 IU, from the product label.

Country Life

See all Country Life products
Name
Country Life
Pharmacist Counseling Corner

Vitamin A 10,000 IU by Country Life: Common Questions

Does Vitamin A 10,000 IU by Country Life interact with any medications?
Yes. Based on its ingredients, Vitamin A 10,000 IU has a known interaction with 387 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin A 10,000 IU contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is vitamin A used for?
Vitamin A is proven effective for treating vitamin A deficiency. It's also possibly effective for oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia, though the evidence for those uses is not yet conclusive.
Is it safe to take high doses of vitamin A?
No. Vitamin A is fat-soluble and builds up in your body, so high doses become toxic. Stick to recommended amounts. Very high doses can cause liver damage, brain swelling, vision problems, and serious neurological effects. Chronic overuse causes skin peeling, hair loss, and brittle nails.
Can I take this if I'm pregnant?
The safety data is mixed: normal dietary and recommended supplement amounts are considered likely safe, but high-dose vitamin A—especially the retinol form—is rated possibly unsafe and can cause birth defects. Talk with your pharmacist or doctor about what's appropriate for you during pregnancy.
Can I take this with warfarin?
High doses of vitamin A may increase bleeding risk with warfarin. The safety data advises keeping vitamin A intake at or below 10,000 IU daily if you're on warfarin. Check with your pharmacist before starting.
What are the side effects?
At recommended doses below the upper limit, vitamin A is generally well tolerated. At high doses, it can cause fatigue, headache, blurred vision, dry and peeling skin, hair loss, and brittle nails. In very high doses or acute overdose, especially in children, it can cause dizziness, delirium, and coma.
How much vitamin A is in this softgel?
Each softgel contains 10,000 IU of vitamin A. That's at the upper limit of recommended intake for adults, so don't exceed the recommended dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vitamin A 10,000 IU is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin A 10,000 IU label
Go deeper

The Full Monographs Behind Vitamin A 10,000 IU’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vitamin A 10,000 IU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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