Vitamin B2 300 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Vitamin B2 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vitamin B2 300 mg is a dietary supplement by Dr. Clark Store with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vitamin B2 300 mg by Dr. Clark Store
Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B2 300 mg by Dr. Clark Store — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vitamin B2 300 mg by Dr. Clark Store
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: 300 mg of Vitamin B2 (riboflavin), a B vitamin your body uses for energy production and cell growth. It comes in a gelatin capsule.
Does it work?
Couldn't assess
The product facts don't include effectiveness data for Vitamin B2 at this dose, so we can't tell you what the evidence shows it works for based on the information we hold.
How safe is it?
Well-documented data
Riboflavin is generally well tolerated. The most common side effects are dose-related nausea and bright yellow urine—the urine color is harmless and just means your body is getting rid of what it doesn't use.
A small number of people have reported diarrhea or increased urination at higher doses. Riboflavin is needed during pregnancy and is generally safe at recommended amounts, but check with your provider before using this high-dose supplement.
It's also needed while breastfeeding and generally safe at recommended amounts; talk to your provider about whether higher doses are right for you.
Meds to double-check
Moderate interaction found
If you take tetracycline antibiotics (like doxycycline, tetracycline, or minocycline), check with your doctor or pharmacist before starting this supplement. Riboflavin may theoretically reduce how well these antibiotics work, and while this hasn't been seen in actual patients, it's worth confirming with your provider that it's safe for your situation.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Vitamin B2 is a safe, well-tolerated nutrient for most people. The main thing to watch is if you take tetracycline antibiotics—check with your doctor or pharmacist first to make sure it's okay to use them together.
If you're pregnant or breastfeeding, or have any questions about whether this supplement fits your health picture, talk it over with your own provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vitamin B2 300 mg, straight from the product label.
| Brand | Dr. Clark Store |
|---|---|
| Barcode (UPC) | 652384104661 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2020 |
| DSLD ID | 215841 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vitamin B2 300 mg by Dr. Clark Store, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Take 1 capsule, preferably with a meal, or as directed by a healthcare professional.
Formulation
Our products don't contain flow agents like magnesium stearate. Not now, not ever.
Supports energy metabolism
Seals/Symbols
Made in USA
Quality Assured GMP
General Statements
Leader in purity Established by Dr. Clark's Family in 1993
Company does not adopt any Dr. Clark claims.
FDA Statement of Identity
Dietary Supplement
Storage
Store at room temperature.
Precautions
Keep away from children.
Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.
If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vitamin B2 300 mg by Dr. Clark Store label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vitamin B2 300 mg by Dr. Clark Store
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Vitamin B2
Interacts with20 drugs
Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...
Vitamin B2 monograph & interactionsOther (inactive) ingredients: Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.
Vitamin B2 300 mg by Dr. Clark Store Drug Interactions
HelloPharmacist Interaction Report
Vitamin B2 300 mg by Dr.
Clark Store contains one active ingredient—riboflavin—which has documented interactions with tetracycline antibiotics (a class of antibiotics used for bacterial infections). The concern is Moderate: in laboratory studies, riboflavin may reduce how well these antibiotics work, though this effect hasn't been reported in actual patients yet, so we don't know if it matters in real life.
Read the full breakdown — every affected drug type, severity by severity
Tetracycline antibiotics are the main medication type to watch. If you take any tetracycline antibiotic (such as doxycycline, tetracycline, or minocycline), check with your doctor or pharmacist before adding this supplement—they can advise you on timing or whether you need to adjust anything.
Altogether, these interactions span 20 individual medications. Use the search tool on this page to check your exact prescriptions.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vitamin B2 300 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vitamin B2 300 mg interact with 20 drugs. Click any drug to see the details.
1 of the 1 ingredient in Vitamin B2 300 mg interact with drugs. Each result below shows which ingredient is responsible. Vitamin B2
Amphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Chlortetracycline interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Demeclocycline interactionDoripenemDoribax
How Doripenem interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycyline interactionEravacyclineXerava
How Eravacycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Eravacycline interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline Hydrochloride interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (oral) interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Retapamulin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tetracycline interactionTigecyclineTygacil
How Tigecycline interacts with Vitamin B2 300 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tigecycline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vitamin B2 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B2
Tetracycline Antibiotics
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Vitamin B2 300 mg, from the product label.
Dr. Clark Store
See all Dr. Clark Store products- Name
- Self Health Resource Center
- Street Address
- 1055 Bay Blvd., Ste A
- City
- Chula Vista
- State
- CA
- ZipCode
- 91911
- Phone Number
- 866-372-5275
- Web Address
- www.DrClarkStore.com
Vitamin B2 300 mg by Dr. Clark Store: Common Questions
Does Vitamin B2 300 mg by Dr. Clark Store interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this turn my urine yellow?
Can I take this if I'm pregnant?
Is it safe to take while breastfeeding?
What side effects should I expect?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vitamin B2 300 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vitamin B2 300 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Vitamin B2 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Riboflavin 5 references
- Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
- MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
- Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC