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Dietary supplement

Vitamin D3 2000 IU Ingredients & Drug Interactions

by Innate Response Formulas

Vitamin D3 2000 IU label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vitamin D3 2000 IU against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Vitamin D3 2000 IU is a dietary supplement by Innate Response Formulas with 7 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 1,078 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Beet, Vitamin D3, Parsley. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Vitamin D3 2000 IU by Innate Response Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin D3 2000 IU by Innate Response Formulas — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Vitamin D3 2000 IU by Innate Response Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 7 active ingredients.
  • “Nourishing Food & Herb Blend” is a proprietary blend — the label gives one combined amount (605 mg) without saying how much of each component you get.

This product has 7 active ingredients: vitamin D3, beet, parsley, carrot, brown rice, broccoli, and Saccharomyces cerevisiae (a beneficial yeast). The main driver is vitamin D3 at 2000 IU—a form of vitamin D your body uses to support bone health and calcium absorption.

The other ingredients are whole-food sources and vegetable powders that provide additional nutrients and phytocompounds. The product also contains inactive ingredients—cellulose, silica, and stearic acid—which are binders and fillers that help hold the tablet together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Supports immune and bone health.
  • We looked for evidence on: Coronavirus disease 2019 (COVID-19), Corticosteroid-induced osteoporosis, Fractures, Hyperparathyroidism-related bone loss, Kidney transplant-related bone loss, Vitamin D deficiency — and 2 related terms.
  • The strongest evidence on file: Vitamin D is rated "Effective" for Vitamin D deficiency (Natural Medicines).
  • Also on file: Vitamin D is rated "Likely Effective" for Corticosteroid-induced osteoporosis.
  • Also on file: Vitamin D is rated "Possibly Effective" for Hyperparathyroidism-related bone loss, Coronavirus disease 2019 (COVID-19).

Vitamin D3 is effective for treating rickets, osteomalacia (soft bones), renal osteodystrophy, hypoparathyroidism, and familial hypophosphatemia—all conditions where the body can't maintain normal vitamin D or calcium. As for the other ingredients in this blend, beet shows possibly effective evidence for athletic performance and exercise-induced muscle soreness.

Broccoli is possibly effective for colorectal cancer prevention. Carrot is possibly effective for vitamin A deficiency.

For most other uses listed in the data—melasma, osteoarthritis, diabetes, dementia, obesity, and several cancers—the evidence is insufficient to rate. Brown rice and parsley lack established effectiveness ratings in our data.

The evidence, ingredient by ingredient Vitamin D Beet Parsley Carrot Brown Rice Broccoli Brewer's Yeast

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

At recommended doses, vitamin D3 is generally well tolerated, though excessive intake over time can cause vitamin D toxicity with symptoms of high blood calcium (hypercalcemia). Beet and carrot are safe as foods but concentrated supplements lack robust safety data, so use caution with higher doses.

Parsley as a food is fine, but medicinal amounts or concentrated extracts may not be safe in large quantities—the facts note that parsley can stimulate the uterus and should be avoided in medicinal amounts during pregnancy. Broccoli as a food is safe; concentrated extracts are less studied.

Brown rice is a common safe food. Carrot, brown rice, and broccoli are likely safe during pregnancy and lactation at normal food amounts.

Beet and parsley have no pregnancy/lactation safety data on file. A small number of people are allergic to carrot or broccoli; broccoli can cause loose stools or cramping at high doses, and beet may cause red or black stools (harmless) or, rarely, kidney damage in very large amounts.

Side effects, ingredient by ingredient Vitamin D Beet Parsley Carrot Brown Rice Broccoli Brewer's Yeast

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 7 matched ingredients can interact with medications — Beet, Brewer's Yeast, Parsley, Vitamin D, Broccoli.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 1,079 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on anticoagulant or antiplatelet drugs (blood thinners like warfarin or aspirin)—parsley carries Moderate-severity bleeding risk. Also verify if you take thiazide diuretics, verapamil, diltiazem, digoxin, atorvastatin, or calcipotriene, as vitamin D3 can interact with these.

If you're on drugs metabolized by CYP3A4, CYP1A2, or CYP2A6 enzymes, check those too—beet, parsley, and broccoli may affect their blood levels. Ask about antidiabetic medications and diuretics as well, since parsley theoretically affects both.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is a whole-food vitamin D supplement useful if you're deficient in vitamin D and want the extra nutrients from the vegetable blend. If you take any prescription medications—especially blood thinners, heart drugs, diuretics, or cholesterol or diabetes medications—talk to your pharmacist or doctor before starting.

The 2000 IU dose of vitamin D is moderate and generally safe, but the parsley content warrants a quick interaction check with your exact medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vitamin D3 2000 IU, straight from the product label.

Brand Innate Response Formulas
Barcode (UPC) 051494401316
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 309008
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vitamin D3 2000 IU by Innate Response Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
051494401316
IngredientAmount% DV
Beet0 NP--
Parsley0 NP--
Carrot0 NP--
Brown Rice0 NP--
Broccoli0 NP--
Saccharomyces cerevisiae0 NP--
Vitamin D350 mcg250%
Nourishing Food & Herb Blend605 mg--

Other ingredients: Cellulose, Silica, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Please recycle 603-216-0899

To learn about our seals, please visit innateresponse.com/standards.

At Innate Response we share your belief that nothing is more important than supporting your body's innate ability to heal. To that end, we develop nutrient-rich supplements.

See how they're made at innateresponse.com/showme. Satisfaction guaranteed or your money back. Learn more at: www.innateresponse.com

Formulation

Supports immune & bone health

Non GMO Glyphosate Residue Free detoxfreeproject.org Tested 125+ Pesticides & herbicides Tested gluten free Dairy free Soy free

Vegetarian

FDA Statement of Identity

Vitamin Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 1 Tablet daily, or as directed by your healthcare practitioner. May be taken anytime throughout the day.

Seals/Symbols

Certified B Corporation Glyphosate Residue Free detoxfreeproject.org Tested 125+ Pesticides & herbicides Tested gluten free OK (Kosher)

Formula

OK (Kosher)

In this Innate Response product each vitamin is paired with an ideal whole food using our unique process to deliver guaranteed potency and the benefit of health-promoting compounds present in the whole food itself.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vitamin D3 2000 IU by Innate Response Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vitamin D3 2000 IU label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vitamin D3 2000 IU by Innate Response Formulas

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin D3

Interacts with
715 drugs
50 mcg per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D3 monograph & interactions

Nourishing Food & Herb Blend

605 mg per serving

Other (inactive) ingredients: Cellulose, Silica, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vitamin D3 2000 IU by Innate Response Formulas Drug Interactions

Want to check YOUR meds against Vitamin D3 2000 IU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,078Drugs
9 Major 965 Moderate 104 Minor

Ingredients driving the most interactions

Beet 861
Vitamin D3 715
Parsley 443
Broccoli 187
Saccharomyces cerevisiae 136

Individual Drug Interactions

The ingredients in Vitamin D3 2000 IU interact with 1,078 drugs. Click any drug to see the details.

5 of the 7 ingredients in Vitamin D3 2000 IU interact with drugs. Each result below shows which ingredient is responsible. Beet Vitamin D3 Parsley Broccoli Saccharomyces cerevisiae

Each ingredient & the kinds of drugs it affects

For each ingredient in Vitamin D3 2000 IU with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet full monograph & interactions

Vitamin D38 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D3 full monograph & interactions

Parsley8 drug types · 443 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, parsley might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Animal research suggests that parsley has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, parsley might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that parsley might decrease blood glucose. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, parsley might increase serum levels of CYP1A2 substrates.
Laboratory research suggests that parsley can inhibit CYP1A2.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, parsley might enhance or interfere with the effects of diuretic drugs.
Animal research suggests that parsley seed extract increases urine elimination. Parsley leaf and root might also interfere with diuretic therapy due their purported aquaretic effects.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, parsley might increase the duration of pentobarbital effects.
Animal research suggests that parsley juice prolongs the action of pentobarbital, perhaps by decreasing cytochrome P450 levels. It is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Sirolimus (Rapamune)

Theoretically, large quantities of parsley might increase sirolimus levels.
In one case report, an adult female with a history of kidney transplant presented with elevated blood sirolimus levels, approximately 4-7 times greater than previous measures, after daily consumption of a juice containing approximately 30 grams of parsley for 7 days. Sirolimus levels returned to normal a week after the parsley juice was discontinued.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, large amounts of parsley leaf and root might decrease the effects of warfarin.
Parlsey contains vitamin K.

Likelihood Possible Evidence D
Aspirin

Theoretically, aspirin might increase the severity of allergic reactions to parsley.
In one case, severe urticaria and swelling were reported after taking aspirin with parsley in an individual with a known mild parsley allergy.

Likelihood Unlikely Evidence D
Parsley full monograph & interactions

Broccoli2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli full monograph & interactions

Saccharomyces cerevisiae4 drug types · 136 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking brewer's yeast with MAOIs might increase the risk of hypertension.
Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs might increase the risk for hypertensive crisis.

Likelihood Likely Evidence D
Antidiabetes Drugs

Taking brewer's yeast with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking chromium-containing brewer's yeast can decrease levels of blood glucose in diabetic patients being treated with antidiabetes drugs.

Likelihood Possible Evidence B
Lithium

Theoretically, taking brewer's yeast with lithium might cause additive effects and side effects.
Some brewer's yeast products contains lithium.

Likelihood Possible Evidence D
Antifungals

Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.
Some brewer's yeast products contain live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces cerevisiae full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vitamin D3 2000 IU, from the product label.

Innate Response Formulas

See all Innate Response Formulas products
Name
MegaFood
Street Address
P.O. Box 5244
City
Manchester
State
NH
ZipCode
03108
Phone Number
800-634-6342
Web Address
www.innateresponse.com
Pharmacist Counseling Corner

Vitamin D3 2000 IU by Innate Response Formulas: Common Questions

Does Vitamin D3 2000 IU by Innate Response Formulas interact with any medications?
Yes. Based on its ingredients, Vitamin D3 2000 IU has a known interaction with 1,078 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vitamin D3 2000 IU contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any fillers or inactive ingredients?
Yes. The inactive ingredients are cellulose, silica, and stearic acid—these are binders and flow agents that help make the tablet. They're common in supplement manufacturing and are not active ingredients themselves.
Is vitamin D3 2000 IU a safe daily dose?
Vitamin D3 at 2000 IU is below the tolerable upper intake level for adults (4000 IU daily), so it's considered safe for long-term use in most people. However, if you're on certain medications—like thiazide diuretics or heart drugs—very high vitamin D intakes can cause high blood calcium, so check with your doctor about your specific situation.
Can I take this if I'm pregnant?
Carrot, brown rice, and broccoli are likely safe during pregnancy at food amounts. However, parsley has safety notes warning against medicinal amounts during pregnancy because it may stimulate the uterus, and beet and vitamin D don't have pregnancy safety data on file. Talk with your doctor or pharmacist about whether this blend is right for you during pregnancy.
What does vitamin D3 actually do?
Vitamin D3 helps your body absorb calcium and maintain bone strength. It's effective for treating conditions like rickets (soft bones in children), osteomalacia (soft bones in adults), and related disorders where the body can't regulate vitamin D or calcium normally.
Will beet or the other vegetables stain my stool or urine?
Beet can cause red or black-colored stools, which is harmless and not a sign of bleeding. This is a normal pigment effect. It may also rarely cause red urine. Carrot is generally well tolerated with no reported staining effects in the data.
Is there enough evidence that the other ingredients in this blend actually work?
Beet shows possibly effective evidence for athletic performance and exercise soreness. Broccoli is possibly effective for colorectal cancer. Carrot is possibly effective for vitamin A deficiency. For most other health claims, the evidence is insufficient to rate or is limited. This blend is primarily a vitamin D3 product with added whole-food nutrition.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vitamin D3 2000 IU label
Go deeper

The Full Monographs Behind Vitamin D3 2000 IU’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph → Herb & supplement monograph

Parsley

Interacts with 443 drugs

Parsley is a popular culinary herb that is safe to eat in normal food amounts and is a good source of vitamins K and C. It is traditionally used as a diuretic and for digestion, but solid hu...

Read the full Parsley monograph → Herb & supplement monograph

Carrot

Carrot is a common food vegetable that is a rich source of beta-carotene (which the body turns into vitamin A) and other nutrients. Eating carrots is safe and nutritious for most people, but...

Read the full Carrot monograph → Herb & supplement monograph

Brown Rice

Brown rice is a whole grain that keeps its fiber-rich bran and nutrient-packed germ, making it more nutritious than white rice. As part of a balanced diet, it may support heart health, diges...

Read the full Brown Rice monograph → Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Brewer's Yeast

Interacts with 136 drugs

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some types of diarrhea. Most other health cla...

Read the full Brewer's Yeast monograph →
Sources

Sources & How We Checked

Vitamin D3 2000 IU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 87 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
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Parsley 21 references
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Carrot 14 references
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Brown Rice 1 reference
  1. FDA, Center for Food Safety and Applied Nutrition, Office of Premarket Approval, EAFUS: A food additive database. Website: vm.cfsan.fda.gov/~dms/eafus.html (Accessed 23 February 2006).

See these in context on the Brown Rice monograph →

Broccoli 5 references
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Brewer's Yeast 6 references
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Vitamin D 26 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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