Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

White Mulbery Ultra Ingredients & Drug Interactions

by Thrive Naturals

White Mulbery Ultra label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking White Mulbery Ultra against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

White Mulbery Ultra is a dietary supplement by Thrive Naturals with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Mulberry leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against White Mulbery Ultra by Thrive Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with White Mulbery Ultra by Thrive Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of White Mulbery Ultra by Thrive Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

White Mulberry Ultra contains one active ingredient: mulberry leaf extract. This comes from the leaves of the white mulberry plant and is the component responsible for the supplement's effects.

The capsules also contain vegetable cellulose as an inactive ingredient to hold the extract together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see White Mulberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight loss and appetite control with metabolism support.
  • We looked for evidence on: Obesity, Hyperlipidemia, Hypertension, Diabetes, Impaired glucose tolerance (prediabetes), Metabolic support — and 2 related terms.
  • The closest evidence on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia, Hypertension, Obesity, Impaired glucose tolerance (prediabetes).

The evidence for mulberry leaf extract isn't yet established in reliable clinical data. Our information shows insufficient evidence to rate it for androgenic alopecia (hair loss), osteoporosis, common cold, diabetes, and high cholesterol.

While research suggests mulberry leaf may lower blood glucose, that's not the same as proof it works as a diabetes treatment or prevents these other conditions. If you're considering this for a specific health goal, that's worth discussing with your doctor.

The evidence, ingredient by ingredient White Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mulberry leaf extract is generally well tolerated when taken by mouth. The most common side effects in clinical trials were bloating and flatulence — reported in about half of participants taking 4.6 grams three times daily — along with loose stools in about a quarter and constipation in a fifth.

The good news is that these digestive effects often lessened over time, suggesting they may be temporary for some people. The safety data available is limited for concentrated supplements, especially in pregnancy and breastfeeding.

Because there isn't enough data to know whether medicinal amounts are safe during pregnancy or while breastfeeding, you should avoid this product in those situations and talk with your doctor or pharmacist.

Side effects, ingredient by ingredient White Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — White Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product before taking it if you use antidiabetes drugs or insulin — mulberry leaf can lower blood sugar and increase the risk of hypoglycemia (Moderate severity). Also check any medications that are OCT2 substrates, especially if you take metformin, as the supplement may slow how your body clears these drugs (Moderate severity).

Use the search tool on this page to verify your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Mulberry leaf extract may appeal to you if you're exploring natural approaches to blood sugar or other concerns — but the evidence for its effectiveness isn't well established yet. If you take any diabetes medication, blood sugar medication, or drugs processed through your kidneys (like metformin), check with your pharmacist before starting this.

Anyone pregnant or breastfeeding should skip it until you've talked with your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about White Mulbery Ultra, straight from the product label.

Brand Thrive Naturals
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2015
DSLD ID 47505
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for White Mulbery Ultra by Thrive Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Mulberry leaf extract500 mg--

Other ingredients: Vegetable Cellulose, May contain one or both of the following

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

All Natural weight loss & appetite control

Pure & Potent Promotes increased metabolism Promotes Cardiovascular health

Supports weight loss for all body types

Benefits 100% All natural weight loss Promotes increased metabolism Helps suppress appetite Promotes Cardiovascular health

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Made in USA(R)

GMP Good Manufacturing Practice Consistent Quality

Formulation

Contains NO Wheat, yeast, egg, soy, starch, gluten, lactose, sugar, or artificial color

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one (1) capsule, twice daily, 30 minutes before meals with an 8 oz glass of water.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

White Mulbery Ultra by Thrive Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

White Mulbery Ultra label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in White Mulbery Ultra by Thrive Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Mulberry leaf extract

Interacts with
87 drugs
500 mg per serving Form: Alkaloids, Flavonoids

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...

Mulberry leaf extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, May contain one or both of the following. These complete the product’s ingredient list but are not active constituents.

Interaction report

White Mulbery Ultra by Thrive Naturals Drug Interactions

Want to check YOUR meds against White Mulbery Ultra?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

Mulberry leaf extract 87

Individual Drug Interactions

The ingredients in White Mulbery Ultra interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in White Mulbery Ultra interact with drugs. Each result below shows which ingredient is responsible. Mulberry leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in White Mulbery Ultra with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mulberry leaf extract2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
Mulberry leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for White Mulbery Ultra, from the product label.

Thrive Naturals

See all Thrive Naturals products
Name
Thrive Naturals
Phone Number
1-818-817-8000
Pharmacist Counseling Corner

White Mulbery Ultra by Thrive Naturals: Common Questions

Does White Mulbery Ultra by Thrive Naturals interact with any medications?
Yes. Based on its ingredients, White Mulbery Ultra has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
White Mulbery Ultra contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the side effects?
Mulberry leaf extract is generally well tolerated. The most common side effects are bloating, flatulence, loose stools, and constipation — but these happened in about half or fewer of trial participants and often went away over time. Digestive upset is the main thing to watch for.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety data, so medicinal amounts aren't recommended during pregnancy or while breastfeeding. Talk with your doctor about what's right for you.
Does this actually work for blood sugar?
The evidence isn't reliable enough to say. Our data shows insufficient evidence to rate mulberry leaf for diabetes. While research suggests it may lower blood glucose, that's different from proof it works as a treatment.
Why can't I take this with my diabetes medication?
Mulberry leaf can lower blood glucose on its own, so taking it with diabetes medication could drop your blood sugar too low (hypoglycemia). You'd need to monitor your blood sugar closely, and your doctor might need to adjust your medication — so check with them first.
How many active ingredients are in this?
There's one active ingredient: mulberry leaf extract. The capsule itself is made from vegetable cellulose, which is just the container.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if White Mulbery Ultra is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

White Mulbery Ultra label
Go deeper

The Full Monographs Behind White Mulbery Ultra’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph →
Sources

Sources & How We Checked

White Mulbery Ultra's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Mulberry 6 references
  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed

See these in context on the White Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team