Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Wild Blueberry Ingredients & Drug Interactions

by Fruit Advantage

Wild Blueberry label
See full label image
Capsule Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Blueberry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Wild Blueberry is a dietary supplement by Fruit Advantage with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Wild Blueberry powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Blueberry by Fruit Advantage

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Blueberry by Fruit Advantage — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Blueberry by Fruit Advantage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Wild Blueberry by Fruit Advantage is a single-ingredient supplement: wild blueberry powder in capsule form. The product also contains inactive ingredients — cellulose, magnesium stearate, and silicon dioxide — which are fillers and binders used to hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Brain support and healthy brain function.
  • We looked for evidence on: Age-related cognitive decline, Cognitive function, Memory, Neuroprotection.
  • The closest evidence on file: Blueberry is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Blueberry is rated "Insufficient Reliable Evidence To Rate" for Cognitive function.

The data we hold on blueberry effectiveness is mixed. It's rated possibly ineffective for high blood pressure.

For five other uses — age-related cognitive decline, anxiety, athletic performance, high cholesterol, and heart disease — the evidence isn't established enough to rate. If you're taking this for one of those conditions, talk with us or your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are widely eaten and well tolerated. Freeze-dried blueberry supplements like this one are generally well tolerated too, though some people experience constipation, diarrhea, nausea, or vomiting — in one trial, about one in four participants stopped taking it in the first week due to stomach complaints.

For pregnancy and breastfeeding: eating blueberries is fine, but the safety data on concentrated supplements like this one isn't firm enough yet. Talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take antidiabetes drugs (for low blood sugar risk), flurbiprofen (an anti-inflammatory), or buspirone (for anxiety). All three interactions are rated Minor, but they're worth verifying against your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

This is a simple, single-ingredient blueberry powder that's generally well tolerated. If you take antidiabetes medication, flurbiprofen, or buspirone, check with your pharmacist first.

If you're pregnant, nursing, or experiencing stomach upset with it, talk with us before continuing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Blueberry, straight from the product label.

Brand Fruit Advantage
Barcode (UPC) 824716006138
Net contents 60 Easy-To-Swallow Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276475
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Blueberry by Fruit Advantage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
824716006138
IngredientAmount% DV
Wild Blueberry powder425 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Brain support

Helps support healthy brain function

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Fruit Advantage Fruit for a healthy you!

Formula

Numerous studies and articles have been written about the amazing health benefits of this powerhouse blue fruit. Research indicates blueberries have potent health-promoting antioxidants. These antioxidants, including anthocyanins, may assist in combating free radicals. Free radicals cause cellular damage and place oxidative stress on the body. The compounds in wild blueberries may assist in Maintaining healthy brain function Promoting urinary tract health (similar to cranberries) Maintaining a healthy body Promoting a healthy lifestyle

Suggested/Recommended/Usage/Directions

Recommendations: As a dietary supplement for adults, take one capsule daily with meals or a full glass of water.

Precautions

Keep out of reach of children.

If pregnant or already taking prescription medications, consult a health professional before using this product.

Do not use if safety seal is broken or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Download a FREE copy of the Blueberry Health Report from our website: www.FruitAdvantage.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Blueberry by Fruit Advantage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Blueberry label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Blueberry by Fruit Advantage

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Wild Blueberry powder

Interacts with
88 drugs
425 mg per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Wild Blueberry powder monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wild Blueberry by Fruit Advantage Drug Interactions

Want to check YOUR meds against Wild Blueberry?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Wild Blueberry powder 88

Individual Drug Interactions

The ingredients in Wild Blueberry interact with 88 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Blueberry interact with drugs. Each result below shows which ingredient is responsible. Wild Blueberry powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Blueberry with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Blueberry powder3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Wild Blueberry powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Blueberry, from the product label.

Fruit Advantage

See all Fruit Advantage products
Name
Fruit Advantage
Street Address
7053 M-88 South
City
Bellaire
State
MI
ZipCode
49615
Phone Number
1-877-746-7477
Web Address
www.fruitadvantage.com
Pharmacist Counseling Corner

Wild Blueberry by Fruit Advantage: Common Questions

Does Wild Blueberry by Fruit Advantage interact with any medications?
Yes. Based on its ingredients, Wild Blueberry has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Blueberry contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is wild blueberry safe during pregnancy or breastfeeding?
There isn't enough data yet to know for sure. Eating blueberries as food is fine, but the safety of concentrated supplements like this one during pregnancy and breastfeeding isn't well studied. Talk with your doctor or pharmacist for personalized advice.
What stomach side effects might I get from this?
Constipation, diarrhea, nausea, and vomiting are possible with freeze-dried blueberry supplements. In one trial, about one in four people taking 50 grams daily dropped out in the first week due to these complaints. Start with a lower dose if your stomach is sensitive.
Does blueberry actually lower blood pressure?
The data rates it as possibly ineffective for high blood pressure, so it's not a reliable choice for that. There isn't enough evidence to say whether it works for age-related cognitive decline, anxiety, athletic performance, high cholesterol, or heart disease either.
Can I take this if I'm on diabetes medication?
Check with your pharmacist first. Blueberry may theoretically increase the risk of low blood sugar when combined with antidiabetes drugs, based on research showing it can lower blood glucose.
What's actually in this capsule besides the blueberry?
The capsule contains cellulose, magnesium stearate, and silicon dioxide — these are inactive fillers and binders. The active ingredient is the wild blueberry powder itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Blueberry is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Blueberry label
Go deeper

The Full Monographs Behind Wild Blueberry’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Blueberry

Interacts with 88 drugs

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are mark...

Read the full Blueberry monograph →
Sources

Sources & How We Checked

Wild Blueberry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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