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Dietary supplement

Wild Yam Extract Ingredients & Drug Interactions

by Herbadiet

Wild Yam Extract label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Yam Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Yam Extract is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, menstrual cramps, hormone balance (popular belief).Based on those ingredients, 41 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Yam root extract powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Yam Extract by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Yam Extract by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Yam Extract by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product is a single-ingredient supplement: wild yam root extract powder. Wild yam has a long history in traditional herbalism and is often used by people looking to support comfort during hormonal transitions, though the scientific evidence for its effectiveness is limited.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Wild Yam's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports women health.
  • We looked for evidence on: Menopausal symptoms, Dysmenorrhea, Premenstrual syndrome (PMS), Postmenopausal conditions, Hormone balance, Menstrual health.
  • The closest evidence on file: Wild Yam is rated "Possibly Ineffective" for Menopausal symptoms (Natural Medicines).
  • Also on file: Wild Yam is rated "Insufficient Reliable Evidence To Rate" for Postmenopausal conditions, Premenstrual syndrome (PMS), Dysmenorrhea.

The evidence supporting wild yam for menopausal symptoms is rated possibly ineffective. For other conditions people take it for—gallbladder disease, sexual dysfunction, difficult menstrual periods (dysmenorrhea), and infertility—we don't have enough reliable evidence to say whether it works.

The research is simply too thin or inconclusive on those fronts right now.

The evidence, ingredient by ingredient Wild Yam

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wild yam is generally well tolerated when taken by mouth in the short term for healthy adults. The most common side effects are fever, headache, upset stomach, and vomiting, especially at higher doses.

A rare serious reaction—anaphylaxis—has been reported. There isn't enough safety data to recommend this during pregnancy or while breastfeeding.

One case report documented vision loss in someone taking a multi-ingredient blend that included wild yam, though it's unclear whether wild yam was the culprit. Long-term safety hasn't been well studied.

Side effects, ingredient by ingredient Wild Yam

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Yam.
  • The most serious interaction on file is rated Moderate.
  • For scale: 41 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any estrogen-containing medications—birth control pills, hormone replacement therapy, or estrogen patches—before using this product. Wild yam might interfere with how your body processes these drugs, potentially weakening or strengthening their effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Wild yam may appeal to you if you're exploring herbal options for hormonal support, but the research doesn't support its use for menopausal symptoms, and evidence for other uses is thin. The key concern is its potential interaction with estrogen medications.

If you take any hormone therapy or birth control, talk to your pharmacist before adding this supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Yam Extract, straight from the product label.

Brand Herbadiet
Net contents 0 Not Present
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244441
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Yam Extract by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
1000 mg
IngredientAmount% DV
Wild Yam root extract powder500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Supports Women Health

Standardized Extract Powder Derived from Dioscorea Villosa Roots

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take up to 1000mg daily, or as directed by physician.

Formulation

Free of fillers, binders, artificial ingredients, dairy, soy, wheat, gluten, yeast

V Vegan

Ethically Sourced Scientifically Tested Premium Grade Ingredients

Precautions

Keep out of reach of children.

Pregnant or lactating women should consult your physician before use.

Storage

Store in a dry, cool & dark.

FDA Disclaimer Statement

Warning: This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Batch No. ARK-P125

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Yam Extract by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Yam Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Yam Extract by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Amounts shown are per serving.

Wild Yam root extract powder

Interacts with
41 drugs
500 mg per serving

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for t...

Wild Yam root extract powder monograph & interactions
Interaction report

Wild Yam Extract by Herbadiet Drug Interactions

Want to check YOUR meds against Wild Yam Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
41Drugs
41 Moderate

Ingredients driving the most interactions

Wild Yam root extract powder 41

Individual Drug Interactions

The ingredients in Wild Yam Extract interact with 41 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Yam Extract interact with drugs. Each result below shows which ingredient is responsible. Wild Yam root extract powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Yam Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Yam root extract powder1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Wild Yam root extract powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Yam Extract, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
Street Address
11, Sector - 14
City
Rohtak
State
Haryana
ZipCode
124001
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Wild Yam Extract by Herbadiet: Common Questions

Does Wild Yam Extract by Herbadiet interact with any medications?
Yes. Based on its ingredients, Wild Yam Extract has a known interaction with 41 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Yam Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does wild yam really help with hot flashes and night sweats?
The evidence suggests it probably doesn't. Research rates wild yam as possibly ineffective for menopausal symptoms, so if that's why you're considering it, it's worth exploring other options first.
What are the most common side effects?
Fever, headache, upset stomach, and vomiting—especially if you take higher doses. Most people tolerate it without problems, but these can happen.
Is it safe to use long-term?
There's good safety data for short-term use in healthy adults, but we don't know much about what happens if you take it for months or years. That's a conversation worth having with your pharmacist.
Can I take this if I'm pregnant or breastfeeding?
The safety data isn't there to say yes. We don't have enough information, so we advise against it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about what's right for your situation.
Can wild yam affect my birth control?
Possibly. Wild yam shows estrogenic and anti-estrogenic effects, which means it might change how your body handles estrogen medications, including birth control. Check with your pharmacist about your specific medication before starting this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Yam Extract label
Go deeper

The Full Monographs Behind Wild Yam Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph →
Sources

Sources & How We Checked

Wild Yam Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Yam 7 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  3. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  4. Rosenberg Zand, R. S., Jenkins, D. J., and Diamandis, E. P. Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim.Acta 2001;312(1-2):213-219. PubMed
  5. Araghiniknam M, Chung S, Nelson-White T, and et al. Antioxidant activity of Dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sciences 1996;59:L147-L157.
  6. Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
  7. Lu J, Wong RN, Zhang L, et al. Comparative analysis of proteins with stimulating activity on ovarian estradiol biosynthesis from four different Dioscorea species in vitro using both phenotypic and target-based approaches: implication for treating menopaus

See these in context on the Wild Yam monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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