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Dietary supplement

Wild Yam Root Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Wild Yam Root Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wild Yam Root Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wild Yam Root Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, menstrual cramps, hormone balance (popular belief).Based on those ingredients, 41 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Yam powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wild Yam Root Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Wild Yam Root Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wild Yam Root Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 24, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wild yam powder. Wild yam has been used traditionally to support various aspects of female health, though modern evidence for most of those uses is limited or mixed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Wild Yam product and its label doesn't state a use — see Wild Yam's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for wild yam is modest. It's rated possibly ineffective for menopausal symptoms.

For gallbladder disease, sexual dysfunction, painful menstrual periods (dysmenorrhea), and infertility, we don't have enough reliable evidence to say whether it works. If you're considering wild yam for one of these reasons, talk with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Wild Yam

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wild yam is generally well tolerated when taken orally for short-term use in healthy adults. Common side effects include fever, headache, upset stomach, and vomiting — especially at higher doses.

Long-term safety hasn't been well studied, so we don't know what happens with ongoing use. Rarely, anaphylaxis (a severe allergic reaction) has been reported.

During pregnancy and breastfeeding, there isn't enough safety data, so the evidence advises against use in both cases — talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Wild Yam

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wild Yam.
  • The most serious interaction on file is rated Moderate.
  • For scale: 41 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take wild yam, double-check any estrogen-based medications with your doctor or pharmacist — birth control pills, hormone replacement therapy, and similar drugs. Wild yam might increase or decrease their effects, and you need to know how your dose should be managed alongside it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wild yam root may appeal to people exploring traditional options for female reproductive health, but the evidence for most uses is weak or unclear. If you take any estrogen-based medication, check with your doctor or pharmacist first — wild yam's effects on hormone therapy are unpredictable and could be significant.

Avoid it during pregnancy and breastfeeding, and stick to short-term use rather than long-term daily dosing until more safety data exists.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wild Yam Root Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435114749
Net contents 1 Ounce(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282340
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wild Yam Root Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
28
UPC/BARCODE
064435114749
IngredientAmount% DV
Wild Yam powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wild Yam Root Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wild Yam Root Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wild Yam Root Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Wild Yam powder

Interacts with
41 drugs
1000 mg per serving

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for t...

Wild Yam powder monograph & interactions
Interaction report

Wild Yam Root Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Wild Yam Root Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
41Drugs
41 Moderate

Ingredients driving the most interactions

Wild Yam powder 41

Individual Drug Interactions

The ingredients in Wild Yam Root Powder interact with 41 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wild Yam Root Powder interact with drugs. Each result below shows which ingredient is responsible. Wild Yam powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Wild Yam Root Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Yam powder1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Wild Yam powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wild Yam Root Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Wild Yam Root Powder by TerraVita Premium Collection: Common Questions

Does Wild Yam Root Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Wild Yam Root Powder has a known interaction with 41 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wild Yam Root Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take wild yam if I'm on birth control or hormone therapy?
Not without checking with your doctor or pharmacist first. Wild yam can theoretically increase or decrease how estrogen works in your body, so your provider needs to weigh the risk and may adjust your dose or monitoring. Don't start wild yam on your own if you're on hormone medications.
Will wild yam help with hot flashes and night sweats?
The evidence suggests it's likely ineffective for menopausal symptoms. If you're looking for relief from hot flashes or other menopause signs, talk with your doctor about options with stronger evidence behind them.
What are the most common side effects?
Fever, headache, upset stomach, and vomiting are the most common, especially at higher doses. These are usually mild, but if they persist or worsen, stop taking it and speak with your pharmacist or doctor.
Is wild yam safe to take long-term?
The safety data we have covers short-term use in healthy adults, but long-term safety hasn't been well studied. It's best to use it short-term rather than as an ongoing daily supplement until more information is available.
Can I take wild yam while I'm pregnant or breastfeeding?
No — there isn't enough safety data for either pregnancy or breastfeeding, so the evidence advises against it. Talk with your doctor or pharmacist if you're considering it during these times.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wild Yam Root Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wild Yam Root Powder label
Go deeper

The Full Monographs Behind Wild Yam Root Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph →
Sources

Sources & How We Checked

Wild Yam Root Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wild Yam 7 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  3. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  4. Rosenberg Zand, R. S., Jenkins, D. J., and Diamandis, E. P. Effects of natural products and nutraceuticals on steroid hormone-regulated gene expression. Clin Chim.Acta 2001;312(1-2):213-219. PubMed
  5. Araghiniknam M, Chung S, Nelson-White T, and et al. Antioxidant activity of Dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sciences 1996;59:L147-L157.
  6. Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
  7. Lu J, Wong RN, Zhang L, et al. Comparative analysis of proteins with stimulating activity on ovarian estradiol biosynthesis from four different Dioscorea species in vitro using both phenotypic and target-based approaches: implication for treating menopaus

See these in context on the Wild Yam monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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