Witch Hazel Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Witch Hazel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Witch Hazel is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for skin irritation and inflammation, hemorrhoids, minor cuts and bruises.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Witch Hazel by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: witch hazel leaf and young twig extract. Witch hazel has been used traditionally for its astringent properties—it helps tighten and tone skin.
The extract is suspended in a base of cane alcohol, distilled water, and glycerin.
Does it work?
Moderate evidence
Witch hazel is possibly effective for hemorrhoids. For varicose veins and postmenopausal conditions, the evidence isn't established enough to rate it one way or the other.
For eczema (atopic dermatitis), the data suggest it's likely ineffective. Keep in mind that most of the research and traditional use center on topical application—that's what the evidence backs.
How safe is it?
Well-documented data
Topically, witch hazel is generally well tolerated, though a small number of people develop contact dermatitis—redness or burning where it's applied. The product is not meant to be taken by mouth.
If you do take it orally, appropriate doses seem well tolerated, but high doses may cause adverse effects because of the tannin content; in rare cases, high-dose oral use of tannin-rich preparations has been linked to kidney and liver damage. There's also some concern from older research that regular consumption of high-tannin herbs may be associated with certain cancers, though other evidence suggests tannins may be protective.
Avoid applying to the nipple area. Talk with your doctor before using this product if you're pregnant or breastfeeding, since safety data are limited.
Meds to double-check
No known interactions
No interactions are documented in our data for witch hazel. Still, run your specific medications through the checker on this page if you want to be certain.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Witch hazel is a reasonable choice if you're looking for topical relief from hemorrhoids. It's generally well tolerated on the skin short-term and has no documented drug interactions.
Don't use it orally unless your doctor approves, and if you're pregnant, breastfeeding, or have liver or kidney concerns, check with your pharmacist or doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Witch Hazel, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090800000478 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 307763 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Witch Hazel by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Witch Hazel Leaf & Young Twig Extract | 685 mg | -- |
Other ingredients: Cane Alcohol, Water, Distilled, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Hamamelis virginiana
Witch Hazel liquid extract
Formulation
Optimal well-being
Gluten-free
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Witch Hazel by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Witch Hazel by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Witch Hazel Leaf & Young Twig Extract
No knowninteractions
Witch hazel is a plant-based astringent used mostly on the skin for minor irritation, hemorrhoids, and oily skin. It is generally well tolerated as a...
Witch Hazel Leaf & Young Twig Extract monograph & interactionsOther (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.
Witch Hazel by Herb Pharm Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Witch Hazel. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Witch Hazel, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Witch Hazel by Herb Pharm: Common Questions
Does Witch Hazel by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I use witch hazel if I'm pregnant or breastfeeding?
Will witch hazel help my eczema?
What's the most common side effect if I use it on my skin?
Is it safe to swallow witch hazel?
What does witch hazel do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Witch Hazel is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Witch Hazel’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Witch Hazel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Witch Hazel 7 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
- Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
- Wolff, H. H. and Kieser, M. Hamamelis in children with skin disorders and skin injuries: results of an observational study. Eur.J.Pediatr. 2007;166(9):943-948. PubMed
- Khanna, N. and Datta, Gupta S. Rejuvenating facial massage--a bane or boon? Int J Dermatol. 2002;41(7):407-410. PubMed
- Theisen LL, Erdelmeier CA, Spoden GA, Boukhallouk F, Sausy A, Florin L, Muller CP. Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus. PLoS One. 201 PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC