Woman's Choice Ingredients & Drug Interactions
by Herbalife
What is this page for?
First and foremost: checking Woman's Choice against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Woman's Choice is a dietary supplement by Herbalife with 3 active ingredients. Its ingredients are commonly taken for alcohol cravings and reduction, menopausal symptoms, heart and blood vessel health.Based on those ingredients, 1,001 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Soy Isoflavone Concentrate, Kudzu extract, Chasteberry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Woman's Choice by Herbalife
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HelloPharmacist Scorecard of Woman's Choice by Herbalife
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 3 of its 3 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.
Why this rating?
- 3 of the 3 matched ingredients can interact with medications — Kudzu, Vitex Agnus-castus, Soy.
- The most serious interaction on file is rated Major.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
- For scale: 1,002 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 3 of 3.
- General safety write-ups exist for 3 of 3.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Woman's Choice, straight from the product label.
| Brand | Herbalife |
|---|---|
| Barcode (UPC) | 1061 |
| Net contents | 30 Tablet(s) |
| Market status | Off market |
| Date entered into DSLD | Nov 25, 2011 |
| DSLD ID | 2115 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Adult Female (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Woman's Choice by Herbalife, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Kudzu extract | 50 mg | -- |
| Chasteberry extract | 12 mg | -- |
| Soy Isoflavone Concentrate | 150 mg | -- |
Other ingredients: Calcium Carbonate, Microcrystalline Cellulose, Corn Starch, Maltodextrin, Gum Arabic, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Sodium Carboxymethylcellulose, Dextrin, Lecithin, Sodium Citrate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
DIETARY SUPPLEMENT
FDA Disclaimer Statement
* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
For Menopausal Support*
Peel Here
Precautions
CONTAINS SOY
General
L1061US-00
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Woman's Choice by Herbalife label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Woman's Choice by Herbalife
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Kudzu extract
Interacts with584 drugs
Kudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Earl...
Kudzu extract monograph & interactionsChasteberry extract
Interacts with121 drugs
Vitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS sympto...
Chasteberry extract monograph & interactionsSoy Isoflavone Concentrate
Interacts with611 drugs
Soy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones. Eating soy foods as part of a balanced diet is g...
Soy Isoflavone Concentrate monograph & interactionsOther (inactive) ingredients: Calcium Carbonate, Microcrystalline Cellulose, Corn Starch, Maltodextrin, Gum Arabic, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Sodium Carboxymethylcellulose, Dextrin, Lecithin, Sodium Citrate. These complete the product’s ingredient list but are not active constituents.
Woman's Choice by Herbalife Drug Interactions
Woman's Choice contains 3 ingredients, and 3 of them have known drug interactions. Altogether they interact with 1,001 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Woman's Choice?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Woman's Choice interact with 1,001 drugs. Click any drug to see the details.
3 of the 3 ingredients in Woman's Choice interact with drugs. Each result below shows which ingredient is responsible. Soy Isoflavone Concentrate Kudzu extract Chasteberry extract
AmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Amphetamine interactionIsocarboxazidMarplan
How Isocarboxazid interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Isocarboxazid interactionMoclobemideManerix, Moclobemide
How Moclobemide interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Moclobemide interactionOzanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Ozanimod Hydrochloride interactionKudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Ozanimod Hydrochloride interactionPhenelzine SulfateNardil
How Phenelzine Sulfate interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Phenelzine Sulfate interactionRasagilineAzilect
How Rasagiline interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Rasagiline interactionChasteberry ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Extract + Rasagiline interactionSafinamide MesylateXadago
How Safinamide Mesylate interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Safinamide Mesylate interactionChasteberry ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Extract + Safinamide Mesylate interactionSelegilineCarbex, Eldepryl, Emsam, Zelapar
How Selegiline interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Selegiline interactionChasteberry ExtractDopamine Agonists Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Read the full Chasteberry Extract + Selegiline interactionTranylcypromineParnate
How Tranylcypromine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateMonoamine Oxidase Inhibitors (maois) Major
Interaction Summary
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Read the full Soy Isoflavone Concentrate + Tranylcypromine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu Extract + Abciximab interactionAbiraterone
How Abiraterone interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu Extract + Abrocitinib interactionSoy Isoflavone ConcentrateCytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Soy might modestly induce CYP2C9 enzymes.
Read the full Soy Isoflavone Concentrate + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Soy Isoflavone ConcentrateAntidiabetes Drugs Moderate
Interaction Summary
Soy can lower blood glucose and have additive effects with antidiabetes drugs.
Read the full Soy Isoflavone Concentrate + Acarbose interactionKudzu ExtractAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Kudzu Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acebutolol interactionSoy Isoflavone ConcentrateAntihypertensive Drugs Moderate
Interaction Summary
Theoretically soy protein may have additive effects with antihypertensive drugs and increase the risk of hypotension.
Read the full Soy Isoflavone Concentrate + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Chasteberry ExtractAntipsychotic Drugs Moderate
Interaction Summary
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Read the full Chasteberry Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs +1 Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Kudzu Extract + Acetaminophen, Aspirin, Caffeine interactionSoy Isoflavone ConcentrateCaffeine Moderate
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine.
Read the full Soy Isoflavone Concentrate + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Butalbital, Caffeine interactionSoy Isoflavone ConcentrateCaffeine Moderate
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine.
Read the full Soy Isoflavone Concentrate + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractCaffeine, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
Read the full Kudzu Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionSoy Isoflavone ConcentrateCaffeine Moderate
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine.
Read the full Soy Isoflavone Concentrate + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Woman's Choice — through 1 ingredient. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Woman's Choice — through 2 ingredients. Tap an ingredient for the detail:
Kudzu ExtractHepatotoxic Drugs, Caffeine Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Kudzu Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSoy Isoflavone ConcentrateCaffeine Moderate
Interaction Summary
Theoretically, soy might reduce the clearance of caffeine.
Read the full Soy Isoflavone Concentrate + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Woman's Choice with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Soy Isoflavone Concentrate
Monoamine Oxidase Inhibitors (Maois)
Taking soy products containing high amounts of tyramine along with MAOIs can increase the risk of hypertensive crisis.
Fermented soy products such as tofu and soy sauce contain tyramine, a naturally occurring chemical that affects blood pressure regulation. The metabolism of tyramine is decreased by MAOIs. Consuming more than 6 mg of tyramine while taking an MAOI can increase the risk of hypertensive crisis. The amount of tyramine in fermented soy products is usually less than 0.6 mg per serving; however, there can be significant variation depending on the specific product used, storage conditions, and length of storage. Storing one brand of tofu for a week can increase tyramine content from 0.23 mg to 4.8 mg per serving. Advise patients taking MAOIs to avoid fermented soy products that contain high amounts of tyramine.
Antidiabetes Drugs
Soy can lower blood glucose and have additive effects with antidiabetes drugs.
Clinical research shows that whole soy diets and soy-based meals reduce fasting glucose levels in diabetic and non-diabetic individuals. Also, individuals following a soy-based meal replacement plan seem to require lower doses of sulfonylureas and metformin to manage blood glucose levels when compared with individuals following a diet plan recommended by the American Diabetes Association.
Antihypertensive Drugs
Theoretically soy protein may have additive effects with antihypertensive drugs and increase the risk of hypotension.
Although some contradictory research exists, most clinical evidence suggests that consuming soy protein modestly reduces systolic and diastolic blood pressure in individuals with prehypertension or hypertension.
Caffeine
Theoretically, soy might reduce the clearance of caffeine.
Soy contains genistein. Taking genistein 1 gram daily for 14 days seems to inhibit caffeine clearance and metabolism in healthy females. This effect has been attributed to inhibition of the cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if this effect occurs with the lower amounts of genistein found in soy.
Diuretic Drugs
Theoretically, soy might have additive effects when used with diuretic drugs.
Animal research suggests that genistein, a soy isoflavone, increases diuresis within 6 hours of subcutaneous administration in rats. The effects seem to be similar to those of furosemide. This effect has not been reported in humans.
Estrogens
Theoretically, soy might competitively inhibit the effects of estrogen replacement therapy.
Soy contains phytoestrogens and has been shown to have estrogenic activity in some patients. Although this has not been demonstrated in humans, theoretically, concomitant use of soy with estrogen replacement therapy might reduce the effects of the estrogen replacement therapy.
Levothyroxine (Synthroid, Others)
Soy products might reduce the absorption of levothyroxine in some patients.
Preliminary clinical research and a case report suggest that soy-based formulas inhibit the absorption of levothyroxine in infants with congenital hypothyroidism. A levothyroxine dosage increase may be needed for infants with congenital hypothyroidism while using soy-based formulas, and the dose may need to be reduced when soy-based formulas are no longer administered. However, in postmenopausal adults, clinical research shows that taking a single dose of soy extract containing isoflavones 60 mg along with levothyroxine does not affect the oral bioavailability of levothyroxine.
Progesterone
Theoretically, combining soy isoflavones with transdermal progesterone may worsen bone density.
Clinical research suggests that significant bone loss may occur in females with osteoporosis who receive a combination of transdermal progesterone with soy milk containing isoflavones when compared with placebo, soy milk alone, or progesterone alone.
Tamoxifen (Nolvadex)
Theoretically, estrogenic soy isoflavones might alter the effects of tamoxifen.
Laboratory research suggests that genistein and daidzen, isoflavones from soy, can antagonize the antitumor effects of tamoxifen under some circumstances; however, soy isoflavones might have different effects when used at different doses. A relatively low in vitro concentration of soy isoflavones such as 1 microM/L seems to interfere with tamoxifen, whereas high in vitro concentrations such as those >10 microM/L might actually enhance tamoxifen effects. People on a high-soy diet have soy isoflavones levels ranging from 0.1-6 microM/L. Until more is known, advise patients taking tamoxifen to avoid therapeutic use of soy products.
Warfarin (Coumadin)
Theoretically, soy might interfere with the effects of warfarin.
Soy milk has been reported to decrease the international normalized ratio (INR) in a patient taking warfarin. The mechanism of this interaction is not known. However, animal and in vitro research suggests that soy may also inhibit platelet aggregation. Dosing adjustments for warfarin may be necessary.
Antibiotic Drugs
Theoretically, antibiotics may decrease the activity of soy isoflavones.
Intestinal bacteria are responsible in part for converting soy isoflavones into their active forms. Antibiotics may decrease the amount of intestinal bacteria and decrease its ability to convert isoflavones.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Soy might modestly induce CYP2C9 enzymes. However, this effect does not seem to be clinically significant.
In vitro research suggests that an unhydrolyzed soy extract might induce CYP2C9. However, the significance of this interaction is likely minimal. In healthy females taking a specific extract of soy (Genistein Soy Complex, Source Naturals), blood levels of losartan, a CYP2C9 substrate, were not significantly affected.
Kudzu extract
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Chasteberry extract
Antipsychotic Drugs
Theoretically, vitex agnus-castus could interfere with the activity of antipsychotic drugs.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as antipsychotic drugs due to its dopamine agonist effects.
Contraceptive Drugs
Theoretically, vitex agnus-castus could interfere with oral contraceptives.
Vitex agnus-castus might interfere with the efficacy of oral contraceptives due to possible hormone modulating activity.
Dopamine Agonists
Theoretically, vitex agnus-castus could interfere with dopamine agonists.
Vitex agnus-castus might potentiate the actions of dopaminergic agonists due to possible dopaminergic effects.
Estrogens
Theoretically, vitex agnus-castus could interfere with the activity of estrogens.
Vitex agnus-castus has hormone modulating activity that can interfere with the efficacy of hormone replacement therapy.
Metoclopramide (Reglan)
Theoretically, dopaminergic effects of vitex agnus-castus could interfere with metoclopramide.
Vitex agnus-castus might interfere with the action of dopamine antagonists such as metoclopramide due to its possible dopaminergic effects.
Brand information
Manufacturer and brand details for Woman's Choice, from the product label.
Herbalife
- Name
- Herbalife International of America, Inc.
- Street Address
- 800 W. Olympic Blvd., Suite 406
- City
- Los Angeles
- State
- CA
- ZipCode
- 90015
Woman's Choice by Herbalife: Common Questions
Does Woman's Choice by Herbalife interact with any medications?
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The Full Monographs Behind Woman's Choice’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Kudzu
Interacts with 584 drugsKudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...
Read the full Kudzu monograph → Herb & supplement monographVitex Agnus-castus
Interacts with 121 drugsVitex (chasteberry) is an herbal remedy most often used for PMS and menstrual cycle problems, and the strongest evidence is for easing some PMS symptoms. It is generally well tolerated by ma...
Read the full Vitex Agnus-castus monograph → Herb & supplement monographSoy
Interacts with 611 drugsSoy is a nutritious bean that is a staple food and a popular source of plant protein and isoflavones. Eating soy foods as part of a balanced diet is generally considered safe for most people...
Read the full Soy monograph →Sources & How We Checked
Woman's Choice's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 132 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Kudzu 21 references
- Woo J, Lau E, Ho SC, et al. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause. Menopause 2003;10:352-61. PubMed
- Akita H, Sowa J, Makiura M, et al. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48:348-9. PubMed
- Luo ZR, Zheng B. [Effect of Puerarin on platelet activating factors CD63 and CD62P, plasminogen activator inhibitor and C-reactive protein in patients with unstable angia pectoris]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2001;21:31-3 .
- Lee KT, Sohn IC, Kim DH, et al. Hypoglycemic and hypolipidemic effects of tectorigenin and kaikasaponin III in the streptozotocin-lnduced diabetic rat and their antioxidant activity in vitro. Arch Pharm Res 2000;23:461-6.
- Yu Z, Zhang G, Zhao H. [Effects of Puerariae isoflavone on blood viscosity, thrombosis and platelet function]. Zhong Yao Cai 1997;20:468-9.
- Hsu FL, Liu IM, Kuo DH, et al. Antihyperglycemic effect of puerarin in streptozotocin-induced diabetic rats. J Nat Prod 2003;66:788-92. PubMed
- Chiang HM, Fang SH, Wen KC, et al. Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats. Toxicol Appl Pharmacol 2005;209:263-8.
- Zheng, J., Chen, B., Jiang, B., Zeng, L., Tang, Z. R., Fan, L., and Zhou, H. H. The effects of puerarin on CYP2D6 and CYP1A2 activities in vivo. Arch Pharm Res 2010;33(2):243-246. PubMed
- Hsu, H. H., Chang, C. K., Su, H. C., Liu, I. M., and Cheng, J. T. Stimulatory effect of puerarin on alpha1A-adrenoceptor to increase glucose uptake into cultured C2C12 cells of mice. Planta Med 2002;68(11):999-1003.
- Zheng, G., Zhang, X., Zheng, J., Meng, Q., and Zheng, D. [Estrogen-like effects of puerarin and total isoflavones from Pueraria lobata]. Zhong.Yao Cai. 2002;25(8):566-568.
- Qi, B. L. and Qi, B. M. [Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats]. Zhongguo Zhong.Yao Za Zhi. 2002;27(11):850-852.
- Akita, H., Sowa, J., Makiura, M., Akamatsu, H., and Matsunaga, K. Maculopapular drug eruption due to the Japanese herbal medicine Kakkonto (kudzu or arrowroot decoction). Contact Dermatitis 2003;48(6):348-349. PubMed
- Manonai, J., Chittacharoen, A., Theppisai, U., and Theppisai, H. Effect of Pueraria mirifica on vaginal health. Menopause. 2007;14(5):919-924. PubMed
- Chandeying, V. and Sangthawan, M. Efficacy comparison of Pueraria mirifica (PM) against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of climacteric symptoms in perimenopausal women: phase III study. J M
- Virojchaiwong, P., Suvithayasiri, V., and Itharat, A. Comparison of Pueraria mirifica 25 and 50 mg for menopausal symptoms. Arch.Gynecol.Obstet. 2011;284(2):411-419. PubMed
- Hou, Q., Ao, X., Li, G., and Zhang, Y. [Puerarin combined with avandia for diabetic nephropathy]. Zhong.Nan.Da.Xue Xue Bao Yi Xue Ban. 2012;37(1):73-77.
- Kim HJ, Kim H, Ahn JH, Suk JH. Liver injury induced by herbal extracts containing mistletoe and kudzu. J Altern Complement Med 2015;21(3):180-5. PubMed
- Santosh N, Mohan K, Royana S, Yamini TB. Hepatotoxicity of tubers of Indian Kudzu (Pueraria tuberosa) in rats. Food Chem Toxicol. 2010 Apr;48(4):1066-71. PubMed
- Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A. Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol. 2015 Jan-Feb;14(1):7-19. DOI
- Wang D, Qiu L, Wu X, Wei H, Xu F. Evaluation of kudzu root extract-induced hepatotoxicity. J Ethnopharmacol. 2015 Dec 24;176:321-6. PubMed
- Warinsiriruk P, Tantitham C, Cherdshewasart W, Shobeiri SA, Manonai J. Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause. Maturitas 2022;160:4-10. PubMed
Vitex Agnus-castus 23 references
- Wuttke W. Dopaminergic action of extracts of Agnus Castus. Forschende Komplementarmedizen 1996;3:329-30.
- Jarry H, Leonhardt S., Gorkow C, Wuttke W. In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus Castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol 1994;102:448- PubMed
- Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo-controlled study. BMJ 2001;322:134-7. PubMed
- Lauritzen CH, Reuter HD, Repges R, et al. Treatment of premenstrual tension syndrome with Vitex agnus castus: Controlled-double blind versus pyridoxine. Phytomedicine 1997;4:183-9.
- Berger D, Schaffner W, Schrader E, et al. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with premenstrual syndrome (PMS). Arch Gynecol Obstet 2000;264:150-3.
- Loch EG, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend Based Med 2000;9:315-20. PubMed
- Meier B, Berger D, Hoberg E, et al. Pharmacological activities of Vitex agnus-castus extracts in vitro. Phytomedicine 2000;7:373-81. PubMed
- Liu J, Burdette JE, Xu H, et al. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 2001;49:2472-9.. PubMed
- Wuttke W, Jarry H, Christoffel V, et al. Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications. Phytomedicine 2003;10:348-57. PubMed
- Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol 2003;18:191-5..
- Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf 2005;28:319-32..
- Halaska M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. Breast 1999;8:175-81. PubMed
- Prilepskaya VN, Ledina AV, Tagiyeva AV, Revazova FS. Vitex agnus castus: Successful treatment of moderate to severe premenstrual syndrome. Maturitas 2006;55 Suppl 1:S55-63. DOI
- Ma, L., Lin, S., Chen, R., and Wang, X. Treatment of moderate to severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Gynecol.Endocrinol. 2010;26(8):612-616. PubMed
- Ma, L., Lin, S., Chen, R., Zhang, Y., Chen, F., and Wang, X. Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women. Aust.N.Z.J Obstet.Gynaecol. 2010;50(2):189-193. PubMed
- Dinç T, Coskun F. Comparison of fructus agni casti and flurbiprofen in the treatment of cyclic mastalgia in premenopausal women. Ulus Cerrahi Derg. 2014 Mar 1;30(1):34-8 PubMed
- Momoeda M, Sasaki H, Tagashira E, Ogishima M, Takano Y, Ochiai K. Efficacy and safety of Vitex agnus-castus extract for treatment of premenstrual syndrome in Japanese patients: a prospective, open-label study. Adv Ther. 2014 Mar;31(3):362-73. PubMed
- Yavarikia P, Shahnazi M, Hadavand Mirzaie S, Javadzadeh Y, Lutfi R. Comparing the effect of mefenamic Acid and vitex agnus on intrauterine device induced bleeding. J Caring Sci. 2013 Aug 31;2(3):245-54.
- Van Die MD, Burger HC, Teede HG, Bone KM. Vitex agnus castus extracts for female reproductive disorders: a systematic review of clinical trials. Planta Med 2013:79:562-575. PubMed
- Ooi SL, Watts S, McClean R, Pak SC. Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis. J Womens Health (Larchmt). 2020;29(2):262-278. PubMed
- Mollazadeh S, Mirghafourvand M, Abdollahi NG. The effects of Vitex agnus-castus on menstrual bleeding: A systematic review and meta-analysis. J Complement Integr Med. 2019;17(1). pii: /j/jcim.2019.17.issue-1/jcim-2018-0053/jcim-2018-0053.xml.
- Najib FS, Poordast T, Mahmudi MS, Shiravani Z, Namazi N, Omrani GR. Does Vitex Agnus-Castus L. Have Deleterious Effect on Fertility and Pregnancy Outcome? An Experimental Study on Rats for Prediction of Its Safety. J Pharmacopuncture 2022;25(2):106-113. PubMed
- Somuncu E, Solak IHA. Colonic Obstruction Secondary to Phytobezoar Caused by Vitex Agnus-Castus Seeds: A Case Report. J Coll Physicians Surg Pak 2022;32(8):S115-S117. PubMed
Soy 88 references
- Franke AA, Custer LJ, Tanaka Y. Isoflavones in human breast milk and other biological fluids. Am J Clin Nutr 1998;68:1466-73. PubMed
- Albertazzi P, Pansini F, Bonaccorsi G, et al. The effect of dietary soy supplementation on hot flushes. Obstet Gynecol 1998;91:6-11. PubMed
- Lu LJ, Anderson KE, Grady JJ, et al. Decreased ovarian hormones during a soya diet: implications for breast cancer prevention. Cancer Res 2000;60:4112-21.
- Pino AM, Valladares LE, Palma MA, et al. Dietary isoflavones affect sex hormone-binding globulin levels in postmenopausal women. J Clin Endocrinol Metab 2000;85:2797-800. DOI
- Nisley N, Klepser T. Phytoestrogens for the prevention and treatment of osteoporosis. Alt Med Alert 1999 Dec;138-42.
- McMichael-Phillips DF, Harding C, Morton M, et al. Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast. Am J Clin Nutr 1998;68:1431S-5S. PubMed
- Petrakis NL, Barnes S, King EB, et al. Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women. Cancer Epidemiol Biomarkers Prev 1996;5:785-94.
- Baird DD, Umbach DM, Lansdell L, et al. Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women. J Clin Endocrinol Metab 1995;80:1685-90. DOI
- Duncan AM, Underhill KE, Xu X, et al. Modest hormonal effects of soy isoflavones in postmenopausal women. J Clin Endocrinol Metab 1999;84:3479-84. PubMed
- Ginsburg J, Prelevic GM. Lack of significant hormonal effects and controlled trials of phyto-oestrogens. Lancet 2000;355:163-4. PubMed
- Anthony MS. Soy and cardiovascular disease: Cholesterol lowering and beyond. J Nutr 2000;130:662S-3S. PubMed
- Hargreaves DF, Potten CS, Harding C, et al. Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. J Clin Endocrinol Metab 1999;84:4017-24. DOI
- Lamartiniere CA. Protection against breast cancer with genistein: a component of soy. Am J Clin Nutr 2000;71:1705S-7S. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Codina R, Ardusso L, Lockey RF, et al. Sensitization to soybean hull allergens in subjects exposed to different levels of soybean dust inhalation in Argentina. J Allergy Clin Immunol 2000;105:570-6. PubMed
- Anto JM, Sunyer J, Rodriguez-Roisin R, et al. Community outbreaks of asthma associated with inhalation of soybean dust. Toxicoepidemiological Committee. N Engl J Med 1989;320:1097-1102. PubMed
- White MC, Etzel RA, Olson DR, Goldstein IF. Re-examination of epidemic asthma in New Orleans, Louisianna, in relation to the presence of soy at the harbor. Am J Epidemiol 1997;145:432-8.
- Murkies A, Dalais FS, Briganti EM, et al. Phytoestrogens and breast cancer in postmenopausal women: a case control study. Menopause 2000;7:289-96. PubMed
- Setchell KD, Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J Nutr 1999;129:758S-67S. PubMed
- Teixeira SR, Potter SM, Weigel R, et al. Effects of feeding 4 levels of soy protein for 3 and 6 wk on blood lipids and apolipoproteins in moderately hypercholesterolemic men. Am J Clin Nutr 2000;71:1077-84. PubMed
- White LR, Petrovitch H, Ross GW, et al. Brain aging and midlife tofu consumption. J Am Coll Nutr 2000;19:242-55. PubMed
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- Divi RL, Chang HC, Doerge DR. Anti-thyroid isoflavones from soybean: isolation, characterization, and mechanisms of action. Biochem Pharmacol 1997;54:1087-96. PubMed
- de Lemos ML. Effects of soy phytoestrogens genistein and daidzein on breast cancer growth. Ann Pharmacother 2001;35:1118-21. PubMed
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- Ji BT, Chow WH, Yang G, et al. Correspondence re: AH Wu et al, A meta-analysis of soyfoods and risk of stomach cancer: the problem of potential confounders. Cancer Epidemiol Biomarkers Prev 2001;10:570.
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- Cambria-Kiely JA. Effect of soy milk on warfarin efficacy. Ann Pharmacother 2002;36:1893-6.. PubMed
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- Brown BD, Thomas W, Hutchins A, et al. Types of dietary fat and soy minimally affect hormones and biomarkers associated with breast cancer risk in premenopausal women. Nutr Cancer 2002;43:22-30.. PubMed
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- Balk JL, Whiteside DA, Naus G, et al. A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. J Soc Gynecol Investig 2002;9:238-42.. DOI
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- He J, Gu D, Wu X, et al. Effect of soybean protein on blood pressure: A randomized, controlled trial. Ann Intern Med 2005;143:1-9. PubMed
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- Jones JL, Daley BJ, Enderson BL, et al. Genistein inhibits tamoxifen effects on cell proliferation and cell cycle arrest in T47D breast cancer cells. Am Surg 2002;68:575-7. DOI
- Shulman KI, Walker SE. Refining the MAOI diet: tyramine content of pizzas and soy products. J Clin Psychiatry 1999;60:191-3. DOI
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- Post-Skagegard, M., Vessby, B., and Karlstrom, B. Glucose and insulin responses in healthy women after intake of composite meals containing cod-, milk-, and soy protein. Eur J Clin Nutr 2006;60(8):949-954. PubMed
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- Azadbakht, L., Kimiagar, M., Mehrabi, Y., Esmaillzadeh, A., Padyab, M., Hu, F. B., and Willett, W. C. Soy inclusion in the diet improves features of the metabolic syndrome: a randomized crossover study in postmenopausal women. Am J Clin Nutr 2007;85(3):7 PubMed
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- Freni-Titulaer, L. W., Cordero, J. F., Haddock, L., Lebron, G., Martinez, R., and Mills, J. L. Premature thelarche in Puerto Rico. A search for environmental factors. Am.J Dis.Child 1986;140(12):1263-1267. PubMed
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- EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS). Risk assessment for peri- and post-menopausal women taking food supplements containing isolated isoflavones. EFSA J. 2015;13(10):4246. DOI
- Vitolins MZ, Griffin L, Tomlinson WV, et al. Randomized trial to assess the impact of venlafaxine and soy protein on hot flashes and quality of life in men with prostate cancer. J Clin Oncol. 2013;31(32):4092-8. PubMed
- Persiani S, Sala F, Manzotti C, et al. Evaluation of levothyroxine bioavailability after oral administration of a fixed combination of soy isoflavones in post-menopausal female volunteers. Drug Res (Stuttg). 2016;66(3):136-40. PubMed
- Wu AH, Spicer D, Garcia A, et al. Double-blind randomized 12-month soy intervention had no effects on breast MRI fibroglandular tissue density or mammographic density. Cancer Prev Res (Phila). 2015;8(10):942-51. PubMed
- Yagami A, Suzuki K, Nakamura M, et al. Case of anaphylactic reaction to soy following percutaneous sensitization by soy-based ingredients in cosmetic products. J Dermatol. 2015;42(9):917-8. PubMed
- Zhang XM, Zhang YB, Chi MH. Soy protein supplementation reduces clinical indices in type 2 diabetes and metabolic syndrome. Yonsei Med J. 2016;57(3):681-9. PubMed
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