Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Women's Vitality Spore Probiotic Ingredients & Drug Interactions

by Probiogen

Women's Vitality Spore Probiotic label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Women's Vitality Spore Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Women's Vitality Spore Probiotic is a dietary supplement by Probiogen with 6 active ingredients. Its ingredients are commonly taken for candida and yeast overgrowth, gut health support, antimicrobial.Based on those ingredients, 1,050 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cranberry (Vaccinium macrocarpon) whole fruit concentrate, Caprylic Acid, Lactobacillus acidophilus DDS-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Women's Vitality Spore Probiotic by Probiogen

Ask about any prescription or over-the-counter medication and we check it for interactions with Women's Vitality Spore Probiotic by Probiogen — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Women's Vitality Spore Probiotic by Probiogen

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 6 active ingredients.
  • “Women's Probiotic Blend” is a proprietary blend — the label gives one combined amount (57.50 mg) without saying how much of each component you get.

Women's Vitality Spore Probiotic contains 6 active ingredients. Three are spore-forming probiotics—Bacillus coagulans HC, Bacillus subtilis HU58, and Bacillus clausii—along with the common probiotic Lactobacillus acidophilus DDS-1.

These live bacteria are intended to support digestive health. The product also contains caprylic acid (a naturally occurring fatty acid) and cranberry whole fruit concentrate.

The capsules are made from hydroxypropyl methylcellulose and contain cellulose plant fiber as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: women's digestive, urinary and vaginal health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Constipation, Diarrhea, Flatulence, Irritable bowel syndrome (IBS) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Cranberry is rated "Possibly Effective" for Urinary tract infections (UTIs).

Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, bacterial vaginosis, antibiotic-associated diarrhea, and Helicobacter pylori infection. Bacillus coagulans is possibly effective for constipation and irritable bowel syndrome.

Bacillus subtilis is possibly effective for antibiotic-associated diarrhea. Cranberry is possibly effective for urinary tract infections.

For other conditions listed—such as athletic performance, cancer, liver disease, and atopic disease—the evidence is either insufficient to rate or suggests the ingredient is possibly ineffective. Caprylic acid lacks reliable evidence for epilepsy and essential tremor.

The evidence, ingredient by ingredient Caprylic Acid Cranberry Lactobacillus Acidophilus Bacillus Coagulans Bacillus Subtilis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The probiotics in this product are generally well tolerated in healthy adults. Orally, Lactobacillus acidophilus may rarely cause mild gastrointestinal side effects like abdominal pain, bloating, or diarrhea; serious infections (bacteremia, sepsis) have been reported but mainly in severely ill or immunocompromised patients.

Bacillus coagulans and Bacillus subtilis have similar safety profiles with limited data; rare infections have occurred in severely ill patients with central lines or compromised immunity. Caprylic acid is generally recognized as safe in food but lacks study at supplement doses—it may cause mild abdominal discomfort, taste changes, or rarely dizziness and headache.

Cranberry at normal food amounts is well tolerated but concentrated supplements are less studied; high doses can cause diarrhea and gastrointestinal upset.

Side effects, ingredient by ingredient Caprylic Acid Cranberry Lactobacillus Acidophilus Bacillus Coagulans Bacillus Subtilis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Lactobacillus Acidophilus, Cranberry, Bacillus Coagulans, Caprylic Acid, Bacillus Subtilis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 1,051 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on any blood pressure medications (the caprylic acid may increase the risk of low blood pressure), blood thinners like warfarin, pain relievers such as NSAIDs or diclofenac, cholesterol drugs like atorvastatin, or the blood pressure drug nifedipine. Antibiotics will reduce how well the probiotics work—separate the two by several hours if possible.

No interactions are documented for Bacillus clausii, as we hold no data for that ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with irritable bowel syndrome, constipation, urinary tract infections, and antibiotic-associated diarrhea, though evidence varies by ingredient. Because of its multiple medication interactions—especially with blood pressure drugs, blood thinners, NSAIDs, and drugs processed through the liver—you should check your exact prescriptions with the tool on this page before starting.

If you're on antibiotics, take this product several hours apart from your dose. Talk with your doctor or pharmacist before taking it, especially if you're pregnant, breastfeeding, or have a weakened immune system.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Women's Vitality Spore Probiotic, straight from the product label.

Brand Probiogen
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 24, 2023
DSLD ID 288733
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Women's Vitality Spore Probiotic by Probiogen, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
IngredientAmount% DV
Caprylic Acid100 mg--
Lactobacillus acidophilus DDS-10 NP--
Bacillus coagulans HC0 NP--
Bacillus subtilis HU580 NP--
Bacillus clausii0 NP--
Cranberry (Vaccinium macrocarpon) whole fruit concentrate600 mg--
Women's Probiotic Blend57.5 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Cellulose plant fiber

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Why Probiotics? Poor diet, pollutants and antibiotics can all wreak havoc in our gut. Probiotics provide "friendly" bacteria that regulate your inner ecosystem to keep you feeling your best. Probiotics are naturally found in the body and in the environment. Spore probiotics are among the most effective strains that nature has to offer.

Maintains healthy vaginal flora Supports a healthy urinary tract Digestive health & nutrient absorption Healthy immune system support

Microbiologist formulated & clinically proven to outlive the leading probiotics and yogurt

Supports digestive + immune health

100% better survival DNA verified strains Smart Spore Technology

Dairy free Gluten free Soy free Non GMO

Science-backed formula

Made in the USA with domestic and selectively imported ingredients

Contains No: GMO, dairy, wheat, gluten, soy, added artificial colors or flavors.

The Probiogen advantage Survives 100x better vs. yogurt and other leading brands

With probiotics, it's quality over quantity Many leading brands with up to 200+ billion CFUs only guarantee potency at the time of manufacture. Probiogen provides live, viable CFUs that live and thrive in the gut, colonizing to provide true benefits when you need them most. Feel the Probiogen difference. Smart Spore Technology Spores are nature's best probiotics. Unlike other popular strains, spore-formers make it past the harsh gastric system to colonize in the gut for better digestive and overall health.

Formula

Probiotic + key women's health nutrients

HU 58 Guaranteed potency probiotic with DNA verified strains

Storage

Plus no refrigeration needed

Store in a cool, dry place.

General Statements

Aren't high quality probiotics refrigerated? If a probiotic needs to be refrigerated, how will it survive a much warmer and more intense environment like your gastric system? Likely - it won't. Learn more about probiogen spore probiotics

Complete study available at Probiogen.com

Brand IP Statement(s)

Probiogen Probiotics that thrive!

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 2 capsules twice daily after a meal or as directed by your physician.

Precautions

Warning: If you are pregnant or lactating, consult a healthcare professional before using this product.

Do not use this product if the safety seal on the bottle is broken.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Women's Vitality Spore Probiotic by Probiogen label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Women's Vitality Spore Probiotic label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Women's Vitality Spore Probiotic by Probiogen

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Caprylic Acid

Interacts with
262 drugs
100 mg per serving

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While...

Caprylic Acid monograph & interactions

Cranberry (Vaccinium macrocarpon) whole fruit concentrate

Interacts with
714 drugs
600 mg per serving

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...

Cranberry (Vaccinium macrocarpon) whole fruit concentrate monograph & interactions

Women's Probiotic Blend

57.5 mg per serving

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Cellulose plant fiber. These complete the product’s ingredient list but are not active constituents.

Interaction report

Women's Vitality Spore Probiotic by Probiogen Drug Interactions

Want to check YOUR meds against Women's Vitality Spore Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,050Drugs
1,018 Moderate 32 Minor

Ingredients driving the most interactions

Cranberry (Vaccinium macrocarpon) whole fruit concentrate 714
Caprylic Acid 262
Lactobacillus acidophilus DDS-1 182
Bacillus coagulans HC 182
Bacillus subtilis HU58 182

Individual Drug Interactions

The ingredients in Women's Vitality Spore Probiotic interact with 1,050 drugs. Click any drug to see the details.

5 of the 6 ingredients in Women's Vitality Spore Probiotic interact with drugs. Each result below shows which ingredient is responsible. Cranberry (Vaccinium macrocarpon) whole fruit concentrate Caprylic Acid Lactobacillus acidophilus DDS-1 Bacillus coagulans HC Bacillus subtilis HU58

Each ingredient & the kinds of drugs it affects

For each ingredient in Women's Vitality Spore Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cranberry (Vaccinium macrocarpon) whole fruit concentrate6 drug types · 714 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
Cranberry (Vaccinium macrocarpon) whole fruit concentrate full monograph & interactions

Caprylic Acid3 drug types · 262 drugs

Antihypertensive Drugs

Theoretically, caprylic acid might increase the risk of hypotension when used with antihypertensive drugs.
Animal research suggests that caprylic acid might have positive inotropic effects, resulting in reduced arterial pressure and vascular resistance and increased cardiac output.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

Theoretically, caprylic acid might increase plasma concentrations of NSAIDs.
In vitro research suggests that caprylic acid might displace NSAIDs from binding sites on albumin. This effect has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, caprylic acid might increase plasma concentrations of warfarin.
In vitro research suggests that high doses of caprylic acid might displace warfarin from albumin binding sites. This effect has not been reported in humans.

Likelihood Possible Evidence D
Caprylic Acid full monograph & interactions

Lactobacillus acidophilus DDS-11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus DDS-1 full monograph & interactions

Bacillus coagulans HC1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans HC full monograph & interactions

Bacillus subtilis HU581 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bacillus subtilis HU58 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Women's Vitality Spore Probiotic, from the product label.

Probiogen

See all Probiogen products
Name
Probiogen
Street Address
9160 E. Bahia Dr.
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
probiogen.com
Pharmacist Counseling Corner

Women's Vitality Spore Probiotic by Probiogen: Common Questions

Does Women's Vitality Spore Probiotic by Probiogen interact with any medications?
Yes. Based on its ingredients, Women's Vitality Spore Probiotic has a known interaction with 1,050 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Women's Vitality Spore Probiotic contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will antibiotics kill the probiotics in this product?
Yes, theoretically. The Bacillus and Lactobacillus organisms in this product are live and active, so antibiotics taken at the same time may kill a significant number of them and make the probiotic less effective. You should separate your antibiotic dose from this product by several hours if your doctor agrees.
Can I take this if I'm on warfarin?
Not without checking first. Cranberry and caprylic acid may both raise warfarin levels, which could increase bleeding risk. Talk with your doctor or pharmacist before starting this product—they can monitor your blood-thinning levels if it's safe to combine them.
What does the caprylic acid do?
Caprylic acid is a naturally occurring fatty acid. The evidence for what it does isn't reliable—the product facts show insufficient evidence for epilepsy and essential tremor. It does carry theoretical risks with blood pressure drugs and blood thinners, so that's something to discuss with your provider.
Is this safe to take while pregnant or breastfeeding?
For Lactobacillus acidophilus, the data shows it's possibly safe in pregnancy; however, pregnancy and lactation data aren't on file for the other active ingredients. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while nursing.
Can this help prevent urinary tract infections?
Cranberry, one ingredient in this product, is possibly effective for urinary tract infections. However, cranberry is not a substitute for medical treatment if you have an active infection—see your doctor if you think you have a UTI.
What side effects might I notice?
Most common are mild gastrointestinal effects—abdominal discomfort, bloating, diarrhea, or changes in taste. These are usually uncommon. At high doses, cranberry can cause diarrhea and nausea. If you have a weakened immune system, there's a small theoretical risk of serious infection from live probiotics, so talk with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Women's Vitality Spore Probiotic label
Go deeper

The Full Monographs Behind Women's Vitality Spore Probiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Caprylic Acid

Interacts with 262 drugs

Caprylic acid is a medium-chain fatty acid found in coconut oil and palm kernel oil that is popularly used for yeast overgrowth and gut health. While laboratory studies show it has antimicro...

Read the full Caprylic Acid monograph → Herb & supplement monograph

Cranberry

Interacts with 714 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Bacillus Subtilis

Interacts with 182 drugs

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...

Read the full Bacillus Subtilis monograph →
Sources

Sources & How We Checked

Women's Vitality Spore Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 91 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Caprylic Acid 5 references
  1. Massolini G, Aubry AF, McGann A, Wainer IW. Determination of the magnitude and enantioselectivity of ligand binding to rat and rabbit serum albumins using immobilized-protein high performance liquid chromatography stationary phases. Biochem Pharmacol 1993 PubMed
  2. Kristev A, Mitkov D, Lukanov Y, Chapkynov P. The effect of octanoic fatty acid on the cardiovascular system of the guinea pig. Cor Vasa 1989;31(4):321-7.
  3. Hayball PF, Holman JW, Nation RL. Influence of octanoic acid on the reversible protein binding of ketorolac enantiomers to human serum albumin (HSA): comparative liquid chromatographic studies using a HSA chiral stationary phase. J Chromatogr B Biomed App PubMed
  4. Noctor TA, Wainer IW, Hage DS. Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase. J Chromatogr 1992;5 PubMed
  5. Voller B, Lines E, McCrossin G, et al. Dose-escalation study of octanoic acid in patients with essential tremor. J Clin Invest. 2016;126(4):1451-7. PubMed

See these in context on the Caprylic Acid monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
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See these in context on the Lactobacillus Acidophilus monograph →

Bacillus Coagulans 28 references
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See these in context on the Bacillus Coagulans monograph →

Bacillus Subtilis 10 references
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See these in context on the Bacillus Subtilis monograph →

Cranberry 33 references
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See these in context on the Cranberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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