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Dietary supplement

Zea-Tein 20/20 Ingredients & Drug Interactions

by Source Naturals

Zea-Tein 20/20 label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Zea-Tein 20/20 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Zea-Tein 20/20 is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for digestive upset, antimicrobial and antifungal, skin and wound care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Zea-Tein 20/20 by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Zea-Tein 20/20 by Source Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Zea-Tein 20/20 by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Marigold flower extract” is listed as a grouped ingredient — the label gives one combined amount (565 mg) without saying how much of each component you get.

Zea-Tein 20/20 contains two active ingredients: zeaxanthin and lutein, both carotenoids found naturally in the retina and other tissues. The product also includes marigold flower extract, a traditional source of these compounds.

The capsule itself uses hydroxypropyl methylcellulose, a standard inactive ingredient that holds everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Lutein and zeaxanthin for healthy eyes.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Zeaxanthin is possibly effective for age-related macular degeneration (AMD), the leading cause of vision loss in older adults. There isn't enough reliable evidence yet to say whether it helps with cognitive decline or Alzheimer's disease.

Lutein is also possibly effective for AMD and for cataracts. For other conditions the product is sometimes marketed for — retinitis pigmentosa, retinopathy of prematurity, and bronchopulmonary dysplasia — the evidence suggests lutein is likely not effective.

The evidence, ingredient by ingredient Tagetes Zeaxanthin Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both zeaxanthin and lutein are generally well tolerated at the doses typically found in supplements. Lutein at doses up to 20 mg daily has not caused adverse effects in trials.

For pregnancy and breastfeeding, the safety data on concentrated supplements is limited. Both ingredients are rated Likely Safe, but their use during pregnancy and lactation should be discussed with your doctor or pharmacist because supplement safety in these periods hasn't been thoroughly studied — food sources are fine, but supplements are a different story.

Side effects, ingredient by ingredient Tagetes Zeaxanthin Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (insulin, metformin, sulfonylureas, or others), check your specific medications with the tool below before starting — zeaxanthin may increase the risk of low blood sugar. No interactions are documented for lutein.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Zea-Tein 20/20 is for people interested in supporting eye health, particularly for macular degeneration or cataracts. If you take diabetes medications, check with us first — zeaxanthin may lower blood sugar.

Pregnant or breastfeeding? Talk to your pharmacist about whether a supplement is right for you, since the data on concentrated forms is thin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Zea-Tein 20/20, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078026471
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 274009
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Zea-Tein 20/20 by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
021078026471
IngredientAmount% DV
Zeaxanthin20 mg--
Lutein20 mg--
Marigold flower extract565 mg--

Other ingredients: Hydroxypropyl Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formula

Lutein and zeaxanthin for healthy eyes

Lutein and zeaxanthin help shield the eye’s retina from damage by supporting healthy macular pigment density. Source Naturals Zea-Tein 20/20 provides lutein and zeaxanthin, sourced from the marigold flower. These important carotenoid pigments aggregate in the retina and provide protection from the damaging effects of free radicals and ultraviolet light. Clinical studies suggest that this lutein-zeaxanthin dosage can support healthy macular pigment density, visual processing speed, and reaction time. Preliminary evidence also indicates that lutein supplementation may help support healthy cognitive performance.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 capsule daily, preferably with a meal.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

General Statements

Capsules filled by weight, not by volume.

Formulation

Suitable for Vegetarians.

Contains no yeast, dairy, egg, gluten, soy or wheat. Contains no artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright SOURCE NATURALS, INC.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Zea-Tein 20/20 by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Zea-Tein 20/20 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Zea-Tein 20/20 by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Marigold flower extract

No known
interactions
565 mg per serving

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most...

Marigold flower extract monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Zea-Tein 20/20 by Source Naturals Drug Interactions

Want to check YOUR meds against Zea-Tein 20/20?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Zea-Tein 20/20 interact with 86 drugs. Click any drug to see the details.

0 of the 1 ingredient in Zea-Tein 20/20 interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Zea-Tein 20/20 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Zea-Tein 20/20, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Zea-Tein 20/20 by Source Naturals: Common Questions

Does Zea-Tein 20/20 by Source Naturals interact with any medications?
Yes. Based on its ingredients, Zea-Tein 20/20 has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Zea-Tein 20/20 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Zea-Tein 20/20 help prevent or slow down macular degeneration?
Both zeaxanthin and lutein in this product are possibly effective for age-related macular degeneration. That means the evidence supports their use, but it's not ironclad — talk to your eye doctor about whether this supplement fits your overall vision care plan.
Is it safe to take this while breastfeeding?
Both ingredients are rated Likely Safe, but there isn't enough data on concentrated supplement doses during breastfeeding. Lutein is naturally present in breast milk, but higher supplement amounts haven't been well studied. Check with your pharmacist or doctor for personalized advice.
What are zeaxanthin and lutein, and why are they in eye supplements?
They're carotenoids — plant pigments your eye naturally uses, especially in the macula, the part of your retina responsible for sharp central vision. This product gets them from marigold flower extract, a traditional botanical source.
I'm diabetic — can I take this?
Animal studies suggest zeaxanthin may lower blood sugar, which could increase the risk of low blood sugar if you're on diabetes medication. Check your exact drugs with our tool below before you start, and talk to your pharmacist.
Are there any side effects?
Both ingredients are generally well tolerated. Lutein at doses up to 20 mg daily hasn't caused adverse effects in trials. No side effects are documented for zeaxanthin at typical supplement amounts.
Does this product contain fillers or other inactive ingredients I should know about?
It contains hydroxypropyl methylcellulose, which is the capsule material — a standard binder used in supplements. That's the only inactive ingredient listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Zea-Tein 20/20 is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Zea-Tein 20/20 label
Go deeper

The Full Monographs Behind Zea-Tein 20/20’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tagetes

Tagetes (marigold) is a group of flowering plants used in traditional medicine and as a source of plant pigments like lutein. Human evidence for most health benefits is very limited, and the...

Read the full Tagetes monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph →
Sources

Sources & How We Checked

Zea-Tein 20/20's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Tagetes 1 reference
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.

See these in context on the Tagetes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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