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Trihexyphenidyl

Trihexyphenidyl is an anticholinergic medicine used alongside other treatment for parkinsonism and to control movement side effects caused by certain psychiatric and other brain-acting medicines.

Brand names ArtaneTremin
Rx Forms 2
Dr. Brian Staiger, PharmD, BCPS
Reviewed by Last reviewed Jul 10, 2026 Content updated Oct 2, 2026
🧬 Where this information comes from Click to expand

The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 13 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →

✓No current FDA shortage listed · checked Oct 6, 2026
Trihexyphenidyl at a glance The quick version — the full detail is in the Patient Information Guide below.
Dr. Brian Staiger, PharmD, BCPS
The Pharmacist’s Take By · Clinical pharmacist · Written

Trihexyphenidyl (Artane) is an older anticholinergic, meaning it blocks acetylcholine, a nerve messenger, used as an add-on for parkinsonism and to ease the stiffness and tremor some antipsychotic medicines cause; it has been on the market since at least the 1980s and is available as a generic. Dry mouth, blurred vision and constipation are what most people notice, and older adults are more prone to confusion and memory slips, so it starts low after 60. Get prompt help for eye pain or vision changes, overheating with little sweating, or new confusion or hallucinations. Never stop it abruptly, which can bring rebound parkinsonism or neuroleptic malignant syndrome, a dangerous reaction.

Clinical pearls

  • Taking it before meals helps if dry mouth is the problem, while after meals suits people who drool or get stomach upset.
  • Go easy in hot weather, saunas and hard physical work, since it cuts sweating and can let your body overheat.
  • Ask for an eye exam that checks your eye's drainage angle (gonioscopy) before starting, plus eye pressure checks over time.
  • If you also take levodopa, new writhing or jerky movements may mean one dose needs lowering, so report them.
How you get itPrescription only
Comes asTablet, Oral solution
Earliest FDA record1949
Companies listing it with the FDA9
FDA label last updatedJul 2, 2025
FDA’s strongest warning (boxed)None on the label

Patient information guide A plain-language walkthrough of Trihexyphenidyl, written from its FDA label.

What Trihexyphenidyl is used for

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Trihexyphenidyl is used for these conditions:

  • Add-on treatment for all forms of parkinsonism (postencephalitic, arteriosclerotic, and idiopathic).
  • Add-on to levodopa in these forms of parkinsonism.
  • Control of extrapyramidal disorders (movement problems) caused by drugs such as dibenzoxazepines, phenothiazines, thioxanthenes, and butyrophenones.

These uses are listed for Trihexyphenidyl Hydrochloride tablets, oral solution, and syrup.

How Trihexyphenidyl works

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Trihexyphenidyl directly blocks activity of the parasympathetic nervous system. It also relaxes smooth muscle, both directly and indirectly through that nerve effect.

Its effects are similar to atropine, but side effects are usually less frequent and less severe.

Trihexyphenidyl dosage

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Trihexyphenidyl is taken by mouth. Your dose is individualized, starts low, and is increased gradually, especially if you are over 60.

  • It may be taken before or after meals, depending on how you react.
  • If your mouth gets very dry, before meals may be better unless it upsets your stomach.
  • If taken after meals and you get thirsty, mint candies, gum, or water can help.
  • With levodopa, the dose of each may need to be lowered.
  • Do not stop suddenly.

Follow your prescriber and the label.

Dosing details from the FDA-approved label

From the Trihexyphenidyl prescribing information (“Dosage and Administration”). Doses are set by your prescriber for your product, condition, kidney function and age — never change a dose on your own.

  • Idiopathic Parkinsonism
    • 1 mg of trihexyphenidyl HCl may be administered the first day
    • The dose may then be increased by 2 mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily
    • Some patients, chiefly those in the postencephalitic group, may require a total daily dose of 12 to 15 mg
    • Initial dose should be low and increased gradually, especially in patients over 60 years of age; total daily intake is tolerated best divided into 3 doses taken at mealtimes; high doses (>10 mg daily) may be divided into 4 parts, with the fourth at bedtime
  • Drug-Induced Parkinsonism
    • Total daily dosage usually ranges between 5 and 15 mg, although in some cases as little as 1 mg daily has controlled reactions
    • It may be advisable to commence therapy with a single 1 mg dose
    • If extrapyramidal manifestations are not controlled in a few hours, subsequent doses may be progressively increased until satisfactory control is achieved
    • Size and frequency of dose must be determined empirically; the tranquilizer dose may be temporarily reduced when starting trihexyphenidyl
  • Concomitant use with levodopa
    • 3 to 6 mg daily, in divided doses, is usually adequate
    • The usual dose of each may need to be reduced; careful adjustment depending on side effects and degree of symptom control
  • Concomitant use with other parasympathetic inhibitors
    • May be substituted, in whole or in part, for other parasympathetic inhibitors
    • Usual technique is partial substitution initially, with progressive reduction in the other medication as the trihexyphenidyl dose is increased
Read the label’s full dosing text

DOSAGE AND ADMINISTRATION Dosage should be individualized. The initial dose should be low and then increased gradually, especially in patients over 60 years of age. Whether trihexyphenidyl HCl may best be given before or after meals should be determined by the way the patient reacts. Postencephalitic patients, who are usually more prone to excessive salivation, may prefer to take it after meals and may, in addition, require small amounts of atropine which, under such circumstances, is sometimes an effective adjuvant. If trihexyphenidyl HCl tends to dry the mouth excessively, it may be .better to take it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, chewing gum or water. Abrupt withdrawal of treatment for parkinsonism may result in acute exacerbation of parkinsonism symptoms; therefore, abrupt withdrawal should be avoided. Abrupt withdrawal of treatment may result in neuroleptic malignant syndrome (NMS) ( see WARNINGS ). Idiopathic Parkinsonism As initial therapy for parkinsonism, 1 mg of trihexyphenidyl HCl in tablet form may be administered the first day. The dose may then be increased by 2 mg increments at intervals of three to five days, until a total of 6 to 10 mg is given daily. The total daily dose will depend upon what is found to be the optimal level. Many patients derive maximum benefit from this daily total of 6 to 10 mg, but some patients, chiefly those in the postencephalitic group, may require a total daily dose of 12 to 15 mg. Drug-Induced Parkinsonism The size and frequency of the trihexyphenidyl HCl dose needed to control extrapyramidal reactions to commonly employed tranquilizers, notably the phenothiazines, thioxanthenes, and butyrophenones, must be determined empirically. The total daily dosage usually ranges between 5 and 15 mg although, in some cases, these reactions have been satisfactorily controlled with as little as 1 mg daily. It may be advisable to commence therapy with a single 1 mg dose. If the extrapyramidal manifestations are not controlled in a few hours, the subsequent doses may be progressively increased until satisfactory control is achieved.

Excerpted — the section continues on the label. Read the full Dosage and Administration section on DailyMed →

Trihexyphenidyl side effects

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Minor side effects are common, affecting 30 to 50 percent of patients. They often lessen as treatment continues.

Common side effects

  • Dry mouth
  • Blurred vision
  • Dizziness
  • Mild nausea
  • Nervousness
  • Constipation
  • Drowsiness
  • Urinary hesitancy or trouble urinating
  • Trouble starting urination or emptying the bladder

When to get medical help

  • Blurred vision or eye problems: narrow angle glaucoma can worsen, and blindness has been reported. Contact your doctor promptly.
  • Fever, muscle stiffness, confusion, or irregular pulse or blood pressure, especially after reducing or stopping the medicine. These can be signs of neuroleptic malignant syndrome, which can be fatal.
  • Little or no sweating, or overheating, especially in hot weather. Severe lack of sweating and fatal overheating have occurred with anticholinergics.
  • New confusion, memory problems, hallucinations, delusions, or paranoia.
  • Severe constipation or belly swelling, or being unable to pass urine.
  • Worsening parkinsonism symptoms after missing doses or stopping.

Contact your doctor about eye problems, confusion, hallucinations, overheating, or severe constipation or urinary retention.

Trihexyphenidyl warnings and precautions

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  • Glaucoma: it can precipitate angle closure and raise eye pressure. Blindness has been reported.
  • Overheating: reduced sweating can lead to hyperthermia (dangerously high body temperature), especially in hot weather.
  • Neuroleptic malignant syndrome: a potentially fatal reaction reported with dose reduction or stopping. Signs include very high fever, muscle rigidity, altered mental status, and an unstable pulse or blood pressure.
  • Stopping suddenly can also worsen parkinsonism.

Trihexyphenidyl interactions

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Trihexyphenidyl can clash with several types of medicines and substances.

  • Alcohol and CNS depressants: more sedation.
  • Cannabinoids, barbiturates, opiates: additive effects and abuse potential.
  • MAO inhibitors and some tricyclic antidepressants: stronger anticholinergic effects.
  • Levodopa: may increase involuntary movements, so doses may need lowering.
  • Neuroleptics: possible increased risk of tardive dyskinesia (uncontrolled movements).

Interactions listed in the FDA-approved label

From the Trihexyphenidyl prescribing information (“Drug Interactions”): what the manufacturer studied or reported to the FDA.

  • Cannabinoids, barbiturates, opiates, and alcohol: May have additive effects with trihexyphenidyl HCl, and thus an abuse potential exists.
  • Alcohol or other CNS depressants: Concurrent use with trihexyphenidyl HCl may cause increased sedative effects.
  • Monoamine oxidase inhibitors and tricyclic antidepressants with significant anticholinergic activity: May intensify the anticholinergic effects of antidyskinetic agents because of their secondary anticholinergic activities.
  • Neuroleptics: There may be an increased risk for the development of tardive dyskinesia during concomitant administration of anticholinergics and neuroleptics. Prophylactic administration of anticholinergic agents such as trihexyphenidyl to prevent drug-induced parkinsonism during neuroleptic therapy is not recommended.
  • Levodopa: Concomitant administration may increase drug-induced involuntary movements. The usual dose of either trihexyphenidyl or levodopa may need to be reduced during concomitant therapy.
Read the label’s full interactions text

Drug Interactions Cannabinoids, barbiturates, opiates, and alcohol may have additive effects with trihexyphenidyl HCl, and thus, an abuse potential exists. Concurrent use of alcohol or other CNS depressants with trihexyphenidyl HCl may cause increased sedative effects. Monoamine oxidase inhibitors and tricyclic antidepressants possessing significant anticholinergic activity may intensify the anticholinergic effects of antidyskinetic agents because of the secondary anticholinergic activities of these medications. Prophylactic administration of anticholinergic agents, such as trihexyphenidyl, as a prevention of drug-induced parkinsonism during neuroleptic therapy is not recommended. There may be an increased risk for the development of tardive dyskinesia during concomitant administration of anticholinergics and neuroleptics ( see PRECAUTIONS , General ) . The usual dose of either trihexyphenidyl or levodopa may need to be reduced during concomitant therapy, since concomitant administration may increase drug-induced involuntary movements ( see DOSAGE AND ADMINISTRATION ).

Read the full Drug Interactions section on DailyMed →

Not a complete list. The label covers the interactions the manufacturer studied or reported, and our own interaction database does not cover every medicine either. Bring your full medication list, including vitamins and herbal products, to your pharmacist.

Before taking Trihexyphenidyl

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  • Do not use if allergic to trihexyphenidyl or any ingredient.
  • Do not use with narrow angle glaucoma.
  • An eye exam and eye pressure monitoring are advised before and during treatment.
  • Use caution in hot weather or hot work environments.
  • Use extra caution if chronically ill, an alcoholic, or if you have central nervous system disease.
  • Over age 60: a low start and slow increases are advised.

Trihexyphenidyl overdose

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Too much can cause central anticholinergic syndrome: dilated pupils, warm dry flushed skin, fast heartbeat, fever, urinary retention, confusion, agitation, hallucinations, and seizures. It can progress to coma, breathing and heart stopping, and death. Treatment is supportive and symptom-based, and limiting absorption of the drug should be started. Get emergency help right away.

What Trihexyphenidyl does in the body

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Trihexyphenidyl inhibits the parasympathetic nervous system and relaxes smooth muscle. Its effects resemble atropine, but with side effects that are ordinarily less frequent and severe.

How to store Trihexyphenidyl

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Store at 20° to 25°C (68° to 77°F) .

Written from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

46

Supplements & herbs that interact with Trihexyphenidyl

46 supplements and herbal products have documented interactions with Trihexyphenidyl in the licensed clinical database we use. Most are manageable — but your pharmacist should know about everything you take, including vitamins and herbals.

Severity mix
  • Major · 3
  • Moderate · 32
  • Minor · 11
Every supplement checked against Trihexyphenidyl — ranked by severity The full interaction hub: 3 major · 32 moderate · 11 minor · every one linked to its full report. Check Trihexyphenidyl against your exact supplements

Educational information from a licensed clinical database (Natural Medicines) — see our data sources & update cadence. Not medical advice: an interaction being documented does not mean it will happen to you; do not start or stop medications or supplements without professional guidance.

Trihexyphenidyl: pharmacist answers to common questions

Quick, plain-English answers to the questions patients ask most about Trihexyphenidyl — the kind of thing our pharmacy team would talk through with you at the counter.

What am I taking this for?

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Trihexyphenidyl is used with other treatment for parkinsonism, and it often works well alongside levodopa. It is also used to control movement problems caused by certain medicines such as phenothiazines. Your prescriber will tell you which applies to you.

Should I take it with food?

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It can be taken before or after meals, depending on how you feel. If your mouth gets very dry, before meals may help, unless it upsets your stomach. If thirst bothers you after meals, try water, gum, or mint candies.

What side effects should I expect?

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Dry mouth, blurred vision, dizziness, mild nausea, and nervousness are common. They often ease as your body adjusts. Tell your doctor if they bother you, because adjusting the dose can help.

Can I stop it if I feel better?

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Please don't stop it suddenly. Stopping abruptly can make parkinsonism symptoms flare and may cause a serious reaction called neuroleptic malignant syndrome. Talk with your prescriber first.

When should I call my doctor?

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Call about vision changes or eye pain, confusion, hallucinations, trouble urinating, severe constipation, or if you stop sweating or feel overheated. Fever with stiff muscles needs urgent care.

Is it okay to drink alcohol?

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It's best to avoid it. Alcohol can add to the sleepiness this medicine can cause. Tell me about any sedatives, opiates, or antidepressants you take as well.

Is Trihexyphenidyl available over the counter?

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No. Trihexyphenidyl is a prescription medicine: every Trihexyphenidyl product listed with the FDA is prescription only, so it is not sold over the counter. Your prescriber decides whether it is appropriate for you, and your pharmacist dispenses it.

When was Trihexyphenidyl first available?

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The earliest FDA record we hold for Trihexyphenidyl is from 1949: its first approval in Drugs@FDA or its earliest product listing in the NDC Directory, whichever is older. Many older medicines were in use before their first formal FDA approval, so this is the earliest date on record, not necessarily when Trihexyphenidyl was first used.

Who makes Trihexyphenidyl?

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9 companies currently list Trihexyphenidyl products in the FDA's NDC Directory, including Remedyrepack Inc., Actavis Pharma, Inc., Golden State Medical Supply Inc.. That count includes repackagers and distributors as well as manufacturers (companies that sell only the raw ingredient are not counted), so fewer companies actually make it; the label on your bottle names the one that supplied yours.

Answers drafted from the FDA-approved label with AI and reviewed by our pharmacy team. How we use AI →

More about Trihexyphenidyl on HelloPharmacist

Detailed data & references for Trihexyphenidyl Forms & strengths, pricing, billing codes, manufacturers, safety reports and sourcing — the data behind the page. Most people can stop here. Each section below opens on a tap.

Trihexyphenidyl forms and strengths (how it comes)

Trihexyphenidyl is available in 2 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.

Need a version that does not list lactose, a gluten source, a dye or gelatin? Inactive ingredients differ by manufacturer: see Trihexyphenidyl inactive ingredients by manufacturer.

Tablet

By mouth
How this form is used
What it may be used for
  • Trihexyphenidyl Hydrochloride tablets are used as an add-on treatment for parkinsonism.
  • Trihexyphenidyl Hydrochloride tablets are used to control movement side effects caused by certain central nervous system drugs.
Important instructions
  • Trihexyphenidyl Hydrochloride tablets are taken by mouth, with dosing individualized and raised gradually.
  • Trihexyphenidyl Hydrochloride tablets should not be stopped abruptly.
Available strengths 2 strengths
36 FDA-listed product records ⓘ

Oral solution

By mouth
How this form is used
What it may be used for
  • Trihexyphenidyl Hydrochloride oral solution is used as an add-on treatment for parkinsonism.
  • Trihexyphenidyl Hydrochloride oral solution is used to control movement side effects caused by certain central nervous system drugs.
Important instructions
  • Trihexyphenidyl Hydrochloride oral solution is taken by mouth, with dosing individualized and raised gradually.
  • Trihexyphenidyl Hydrochloride oral solution should not be stopped abruptly.
Available strengths 1 strength
5 FDA-listed product records ⓘ

Trihexyphenidyl on the U.S. market: products, makers and brands

How Trihexyphenidyl appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.

9 companies list 17 Trihexyphenidyl product records with the FDA, mostly as tablet, oral solution; the earliest marketing or approval year on record is 1949. Brand names on the directory include Artane, Tremin; the rest are generics.

2
Dose forms ⓘ
9
Labelers (makers, repackagers, distributors)
1
Brand names
17
FDA-listed product records ⓘ
1949
Earliest FDA record ⓘ

FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

Also listed with the FDA, not a patient dose form: Powder (4) — bulk drug substance sold to compounders/manufacturers and multi-item kits. These aren’t counted in the dose-form total above.

Remedyrepack Inc.29%
Actavis Pharma, Inc.12%
Golden State Medical Supply Inc.12%
Natco Pharma Limited12%
Novitium Pharma LLC12%
Akorn6%
Other makers18%

Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.

How widely Trihexyphenidyl is used (Medicaid data)

A general measure of how commonly Trihexyphenidyl is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.

Think of this as a proxy for how widely Trihexyphenidyl is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.

102,119
Medicaid prescriptions filled (Q1–Q4 2025)
$1.6M gross Medicaid reimbursement (before mandatory rebates — net cost is lower)

How commonly is Trihexyphenidyl prescribed? Of the 1,601 medications we measure, Trihexyphenidyl ranks #508 by Medicaid prescriptions — more than 68% of them.

Where Trihexyphenidyl ranks among the drugs we measure · Q1–Q4 2025 · neighbors ±5

Utilization by Trihexyphenidyl product

Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.

The 2 mg oral tablet is the most-dispensed Trihexyphenidyl product — about 57% of these Medicaid prescriptions.

trihexyphenidyl hydrochloride 2 MG Oral Tablet Most dispensed

58,587 Medicaid prescriptions (Q1–Q4 2025) 57% of Trihexyphenidyl prescriptions shown $768,370 gross reimbursement (before rebates) ≈ $13 per prescription (gross)

Summed across the 5 of 29 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 905269

trihexyphenidyl hydrochloride 5 MG Oral Tablet

36,253 Medicaid prescriptions (Q1–Q4 2025) 36% of Trihexyphenidyl prescriptions shown $572,912 gross reimbursement (before rebates) ≈ $16 per prescription (gross)

Summed across the 4 of 31 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 905283

trihexyphenidyl hydrochloride 0.4 MG/ML Oral Solution

7,279 Medicaid prescriptions (Q1–Q4 2025) 7% of Trihexyphenidyl prescriptions shown $306,114 gross reimbursement (before rebates) ≈ $42 per prescription (gross)

Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 905273

Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.

Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Trihexyphenidyl, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 10 of 62 listed Trihexyphenidyl NDCs with Medicaid activity.

Compare Trihexyphenidyl products

A representative set of FDA-listed product records for Trihexyphenidyl — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)

Showing 17 of 17 products — FDA National Drug Code Directory. See every product, package size and price: browse all 17 Trihexyphenidyl NDCs →

Trihexyphenidyl recall history

A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.

The FDA’s enforcement reports list no Trihexyphenidyl recalls since July 2021.

✅No Trihexyphenidyl recalls on record since July 2021

Source: FDA enforcement (recall) reports, via openFDA; our copy was last updated Sep 24, 2026.

RxNorm Concept Web — From Ingredient to Every Form and Strength

This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.

Ingredient (IN) Trihexyphenidyl RxCUI 10811 2 dose forms · 4 strengths
  1. Dose form (SCDF) Oral Solution RxCUI 374213 In current FDA listings
    Clinical drug / strength (SCD) hydrochloride 0.4 MG/ML RxCUI 905273 hydrochloride 1 MG/ML RxCUI 905292

Look up RxCUI 10811 in the RxCUI Atlas →

RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.

💵 What Trihexyphenidyl costs pharmacies (NADAC benchmark)

The national average invoice price pharmacies pay for the drug itself, from CMS's NADAC survey (data as of Sep 30, 2026). This is a supply-cost benchmark — not a retail price and not what you'd pay at the counter.

FormStrengthPharmacy acquisition benchmark
Tablet · Oral 5 mg $0.119 per tablet NDC details & price history
Tablet · Oral 2 mg $0.088 per tablet NDC details & price history
Solution · Oral 2 mg/5 mL $0.159 per mL NDC details & price history
Tablet 2 mg $0.088 per tablet NDC details & price history
Tablet 5 mg $0.119 per tablet NDC details & price history
Why show this? Your out-of-pocket cost depends on insurance, pharmacy markup, and discounts — but the acquisition benchmark tells you whether the medication itself is inexpensive or costly, which strengths cost more per dose, and whether a cash-price quote is in a reasonable range. Each row links to the NDC-level record with its full price history.

Source: CMS National Average Drug Acquisition Cost (NADAC), a survey of retail pharmacy invoice prices. Benchmarks shown are the range across package sizes of a representative product for each form and strength — other manufacturers' products may differ.

Trihexyphenidyl brand names

Trihexyphenidyl is sold under 2 brand names in the FDA directory — Artane, Tremin. A brand and its generic contain the same active ingredient; the brand name belongs to one company's product.

Artane Tremin

Who makes Trihexyphenidyl: manufacturers and labelers

9 companies list Trihexyphenidyl products with the FDA. By number of product records, the largest are Remedyrepack Inc., Actavis Pharma, Inc., Golden State Medical Supply Inc.. Labelers include manufacturers and repackagers; the product in your bottle depends on which one your pharmacy stocks.

Remedyrepack Inc. 5 Actavis Pharma, Inc. 2 Golden State Medical Supply Inc. 2 Natco Pharma Limited 2 Novitium Pharma LLC 2 Akorn 1 Bionpharma Inc. 1 Chartwell RX, LLC 1 PAI Holdings, LLC dba PAI Pharma 1

Trihexyphenidyl drug class (RxNorm)

Trihexyphenidyl belongs to the Tertiary amines class.

Drug family (ATC) Tertiary amines

Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.

Sources for this Trihexyphenidyl page

Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.

📄
FDA-filed drug labels (SPL) Uses, dosing, warnings & side effects from SPL records retrieved through openFDA; the linked representative set can be verified on DailyMed. ✓ Linked label effective Jul 2, 2025
🏭
Forms, brands & labelersAggregated from ingredient-matched FDA National Drug Code Directory product records for Trihexyphenidyl.
📈
Real-world reportsThe FDA Adverse Event Reporting System (FAERS), served through openFDA.
🚨
Recalls & shortagesopenFDA drug-enforcement reports and the FDA drug-shortage database.
🧾 Clinical label set — FDA-filed SPL labels retained for Trihexyphenidyl after exact ingredient or ingredient-combination matching and applicable route/form matching
Clinical labels in scope
13
Finished products in the current FDA directory
17
Companies listing them (makers, repackagers, distributors)
9
FDA labeler codes behind them ⓘ
9
Linked representative label ⓘ
Bionpharma Inc.
Linked label effective
Jul 2, 2025
Composite sections available
17
Linked SPL Set ID
4d4d473e-4f84-43e7-bb17-49e8dc1e97fd
Linked SPL Document ID
38f3f3f8-6374-9981-e063-6294a90aa5df
Open the linked representative label on DailyMed ↗

How this page is built

HelloPharmacist combines public FDA and NLM records and does not author the underlying clinical facts. The plain-language sections are written with AI from the FDA-approved label text and reviewed by our pharmacy team before publication. Bionpharma Inc. is the representative DailyMed label linked for verification and dates. This is general education, not medical advice: always talk to your doctor or pharmacist about your own medicines. How we build and review drug pages →