Systane ULTRA polyethylene glycol 400 and propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops, 25 vials — NDC 0065-1432-06 (Billing 00065-1432-06)
This is a package of 25 vials of Systane ULTRA polyethylene glycol 400 and propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops from Alcon Laboratories, Inc., marketed since Jul 2009 and currently FDA-listed; retail pharmacies pay about $0.4408 per vial (NADAC). It is the main listing for this product, which comes in 3 package sizes.
NDC database record
One package, one record: these facts belong to NDC 0065-1432-06 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 0065 labeler · 1432 product · 06 package
- Package marketed since
- Jul 27, 2009
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2026
- Billing quantity
- 25 EA per package
- Barcode (UPC-A, from the NDC)
- 3 0065143206 0
- Medicaid fills, this package
- 6,428 prescriptions in the last four reported quarters
- FDA record last changed
- Jul 24, 2026
Other active recalls for Polyethylene Glycol 400 And Propylene Glycol (different manufacturers) — 1 · tap to view
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
- GSN (GCN sequence number): 058288
- GCN: 23696
- GPI-14 (Medi-Span): 86209902482022
- HICL (First Databank): 038529
- AHFS class code: 52:92.00.00
- RxCUI (RxNorm): 477589
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 6, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
Clinical
Systane ULTRA is an over-the-counter eye drop solution marketed under FDA's OTC monograph rules for ophthalmic products. It contains two lubricating agents, polyethylene glycol 400 and propylene glycol, which are typically used to moisturize and relieve dryness and irritation of the eye surface. This product functions as an artificial tear replacement for temporary comfort of dry eyes.
Patient education
Supplement & herbal interactions
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 6, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per ea | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.441 | $11.02 / 25 vials |
| Medicaid paysCMS SDUD · 12 mo | $0.8520 | $21.30 / 25 vials |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file · file of Jan 28, 2026
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · through Q1 2026
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Per unit | Per pack | Marketing start | Marketing end | Status |
|---|---|---|---|---|---|---|
| 00065-1432-04 0065-1432-04 | 5 VIAL in 1 CARTON / .7 mL in 1 VIAL | — | — | 2009-07-27 | — | Active |
| 00065-1432-05 0065-1432-05 | 60 VIAL in 1 CARTON / .7 mL in 1 VIAL | $0.3601 / ea | $21.60 | 2009-07-27 | — | Active |
| 00065-1432-06 You're viewing this Main listing | 25 VIAL in 1 CARTON / .7 mL in 1 VIAL | $0.4408 / ea | $11.02 | 2009-07-27 | — | Active |
Per ea, this pack runs about 22% above the cheapest pack (NDC 00065-1432-05, $0.3601 vs $0.4408 NADAC).
In Medicaid, this is the most-dispensed pack of this product — about 89% of fills over the last four reported quarters. See all packs ↓
Pack size FAQ
What quantity is in this package?
How does this package differ from NDC 00065-1432-04?
What NDC number is used to bill for this package of Systane ULTRA polyethylene glycol 400 and propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops?
Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.
Therapeutic equivalents
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file · file of Jan 28, 2026
Availability & generic status
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII LU49E6626Q
A synthetic organic compound used as a pH buffer and neutralizing agent in medicines. It helps maintain the proper acidity level in liquid formulations to improve stability and comfort.
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UNII R57ZHV85D4
Boric acid is a weak acid derived from boron. In medicines, it typically serves as a buffer to help maintain the product's pH level and may act as a preservative in certain formulations.
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UNII E89I1637KE
Guar gum is a natural thickener made from guar bean seeds. It's used in medicines as a binder and thickening agent to hold ingredients together and create the right texture and consistency.
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UNII QTT17582CB
A strong acid used to adjust and maintain the proper pH level in liquid medicines, ensuring stability and preventing breakdown of active ingredients.
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UNII 660YQ98I10
Potassium chloride is a mineral salt used in medicines as a buffer and to help maintain the proper pH balance and stability of the formulation during storage and use.
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UNII 451W47IQ8X
Sodium chloride is common table salt. It's used in medicines as a buffer to maintain proper pH, as a filler to add bulk, or to adjust the osmotic balance in liquid formulations.
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UNII 55X04QC32I
A strong alkaline chemical used to adjust and maintain the pH balance of liquid medicines. It helps keep the medicine stable and ensures it stays effective during storage.
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UNII 506T60A25R
Sorbitol is a natural sugar alcohol derived from glucose. It serves as a sweetener, humectant, and bulking agent in medications to improve taste and help maintain moisture in the product.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
9 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.- FDA label on DailyMed · label index refreshed Oct 6, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Alcon Laboratories, Inc. labeler code 00065
- Tetracaine Hydrochloride 5 mg/mL Solution NDC 0065-0741-14
- BSS balanced salt solution 6.4 mg/mL; .75 mg/mL; .48 mg/mL; .3 mg/mL; 3.9 mg/mL; 1.7 mg/mL Solution NDC 0065-0795-15
- BSS PLUS balanced salt solution enriched with bicarbonate, dextrose, and glutathione Kit NDC 0065-0800-50
- PATADAY ONCE DAILY RELIEF OLOPATADINE HYDROCHLORIDE 7 mg/mL Solution NDC 0065-0816-01
- atropine sulfate 10 mg/mL Solution NDC 0065-0817-01
- Systane Ultra Polyethylene Glycol 400 and Propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-1431-01
- Systane Balance propylene glycol .06 mg/mL Emulsion NDC 0065-1433-02
- SYSTANE HYDRATION PF PRESERVATIVE FREE Polyethylene Glycol 400 and Propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-1437-04
- Systane Day and Night Value Pack Polyethylene Glycol 400, Propylene Glycol 0.3% Kit NDC 0065-1502-10
- Systane Ultra Preservative Free Polyethylene Glycol 400 and Propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-1507-82
- Systane COMPLETE PF propylene glycol .06 mg/mL Emulsion NDC 0065-1509-28
- SYSTANE HYDRATION PF PRESERVATIVE FREE Polyethylene Glycol 400 and Propylene 400 4 mg/mL; 3 mg/mL Solution/ Drops NDC 0065-1510-00
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
Uses For the temporary relief of burning and irritation due to dryness of the eye for temporary relief of discomfort due to minor irritation of the eye or to exposure to wind or sun
⏱️ Dosage and Administration ▾
Directions Put 1 or 2 drops in the affected eye(s) as needed.
⚠️ Warnings ▾
Warnings For external use only. Do not use if this product changes color or becomes cloudy if you are sensitive to any ingredient in this product When using this product do not touch tip of container to any surface to avoid contamination do not reuse once opened, discard Stop use and ask a doctor if you experience any of the following: eye pain changes in vision Continued redness or irritation of the eye Condition worsens or persists for more than 72 hours Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
Active Ingredients Purpose Polyethylene Glycol 400 0.4% Lubricant Propylene Glycol 0.3% Lubricant
🧪 Inactive Ingredients ▾
Inactive Ingredients Aminomethylpropanol, boric acid, hydroxypropyl guar, potassium chloride, purified water, sodium chloride, sorbitol. May contain hydrochloric acid and/or sodium hydroxide to adjust pH.
📄 Do Not Use ▾
For external use only. Do not use if this product changes color or becomes cloudy if you are sensitive to any ingredient in this product
📄 When Using This Product ▾
When using this product do not touch tip of container to any surface to avoid contamination do not reuse once opened, discard
📄 Stop Use and Ask a Doctor If ▾
Stop use and ask a doctor if you experience any of the following: eye pain changes in vision Continued redness or irritation of the eye Condition worsens or persists for more than 72 hours
📄 Keep Out of Reach of Children ▾
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📄 Questions or Comments ▾
Questions? In the U.S. call 1-800-757-9195 www.systane.com
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL Systane ® LUBRICANT EYE DROPS ULTRA PF PRESERVATIVE-FREE DRY EYE RELIEF Convenient Single Vials On-The-Go Great for sensitive eyes Fast-acting hydration and lasting relief Moisture-rich formula #1 Doctor Recommended Brand 1 STERILE 60 Vials 0.7 mL Each Alcon SIDE DISPLAY PANEL Systane ® LUBRICANT EYE DROPS ULTRA PF PRESERVATIVE-FREE DRY EYE RELIEF Convenient Single Vials On-The-Go Open your eyes to a breakthrough in comfort with SYSTANE ® ULTRA Lubricant Eye Drops. SYSTANE ® ULTRA preservative-free vials elevates the science of dry eye therapy to a new level so you can have relief from dry eye anytime, anywhere.
From first blink eyes feel lubricated and refreshed. Feel the difference in dry eye relief with SYSTANE ® ULTRA TAMPER EVIDENT: Do not use if vial is damaged or opened at time of purchase. 1 Based on a survey of eye care professionals.
Data on file. www.alconpatents.com Made in France W435221-0919