Home › NDC Lookup › Ingredients › Simethicone › 00536-1306-08
Gas Relief Ultra Strength Simethicone 180 mg Capsule, Liquid Filled, 60-count — NDC 00536-1306-08 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Gas Relief Ultra Strength Simethicone 180 mg Capsule, Liquid Filled, 60-count — NDC 0536-1306-08 (Billing 00536-1306-08)

by Rugby Laboratories, Inc. · 60 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC

This is a package of 60 capsules of Gas Relief Ultra Strength Simethicone 180 mg Capsule, Liquid Filled from Rugby Laboratories, Inc., marketed since Jul 2020 and currently FDA-listed, this package's marketing is listed to end Oct 2026; retail pharmacies pay about $0.0541 per capsule (NADAC). It is this product's only package size.

NDC 00536-1306-08
🏷️ FDA NDC (as labeled) 0536-1306-08 billing pads the labeler segment with a zero
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 0536-1306-08 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
0536 labeler · 1306 product · 08 package
Package marketed since
Jul 24, 2020
Package marketing ended
Oct 28, 2026
Sample package
No — commercial package
Billing quantity
60 EA per package
Barcode (UPC)
0305361306083
Medicaid fills, this package
716 prescriptions in the last four reported quarters
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 0536-1306-08
Product NDC 0536-1306
11-digit billing NDC 00536130608
NCPDP billing unit EA — each (per item)
RxCUI 252294
UNII 92RU3N3Y1O
UPC 0305361306083
Application # M002
SPL Set ID 24731f4b-ca2b-483f-beed-dfc8104f8133
Physiologic effect Skin Barrier Activity
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2020-07-24
Marketing end 2026-10-28
Route ORAL
Dosage form CAPSULE, LIQUID FILLED
Substance DIMETHICONE

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 52200020000135
GPI class Simethicone Ultra Strength
GCN Seq No 040944
GCN 94652
HICL code 001224
Ingredient (HICL) Simethicone
HIC1 code D
Therapeutic class — broad (HIC1) Biliary System/Gastro-Intestinal System
HIC2 code D4
Therapeutic class — intermediate (HIC2) Drugs Acting Principally On The Alimentary Tract
HIC3 code D4N
Therapeutic class — specific (HIC3) Antiflatulents
AHFS code 56:10.00.00
AHFS class Antiflatulents
FDB label name SIMETHICONE 180 MG SOFTGEL
FDB brand name Simethicone
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 040944
  • GCN: 94652
  • GPI-14 (Medi-Span): 52200020000135
  • HICL (First Databank): 001224
  • AHFS class code: 56:10.00.00
  • RxCUI (RxNorm): 252294
Why two NDCs? The FDA registers this code as 0536-1306-08 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00536-1306-08. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

Label name SIMETHICONE 180 MG SOFTGEL Ingredient Simethicone
📗 Our plain-language guide HelloPharmacist
  • It relieves the discomfort of gas. For adults, that means pressure, bloating and fullness. Infant drops are for baby gas, often caused by swallowed air or certain formulas or foods...
  • Shake the bottle well. Use only the syringe or dropper that came with it. Dispense it slowly toward the inner cheek. You can also mix it with 1 oz. of cool water, formula or anothe...
  • Doses can be repeated as needed after meals and at bedtime. Do not go over 12 doses in a day. Follow your product’s label and your doctor’s advice.
  • If you can, use your child’s weight. If not, use age. Check the chart on your product, and ask me or your doctor if you are unsure.
📖 Read our full Simethicone guide →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.054 $3.25 / 60 capsules
Medicaid paysCMS SDUD · 12 mo $0.1381 $8.29 / 60 capsules
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Jan 2022 Aug 2022 Jan 2026 Sep 2026 $0.066 $0.047
▼ Down 9% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
00536-1306-08 You're viewing this Main listing 60 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC 2020-07-24 Oct 28, 2026 Active

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
good sense gas relief 180 mg 00113-0657-72 L. 60 capsules $0.054 — Availability likely —
Gas Relief Ultra Strength 180 mgthis 00536-1306-08 Rugby 60 capsules $0.054 — Availability likely —
Gas Relief 180 mg 00536-1421-08 Rugby 60 capsules $0.054 — Availability likely —
Gas Relief 180 mg 46122-0769-64 AmerisourceBergen 60 capsules $0.054 — Availability likely —
Gas Relief 180 mg 70677-1093-01 Strategic 60 capsules $0.054 — Availability likely —
Gas Relief 180 mg 70677-1254-01 Strategic 60 capsules $0.054 — Availability likely —
Phazyme 180 mg 00132-0208-12 C.B. 12 capsules $0.228 — FDA listed +321%
Gas-X Ultra Strength AntiGas Softgels 180 mg 00067-6274-18 Haleon 9 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 00363-0833-50 Walgreens 1 capsule — — FDA listed —
Gas Relief Ultra Strength 180 mg 00363-0932-20 Walgreens 1 capsule — — FDA listed —
Gas Relief 180 mg 00363-1510-20 Walgreens 1 capsule — — FDA listed —
Gas Relief Ultra Strength 180 mg 00363-8730-20 Walgreens 1 capsule — — FDA listed —
Gas Relief Ultra Strength 180 mg 00363-8740-20 Walgreens 1 capsule — — FDA listed —
Ultra Strength Gas Relief 180 mg 00363-9941-09 Walgreen 10 capsules — — FDA listed —
Ultra Strength Gas Relief 180 mg 00363-9942-22 Walgreen 60 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 21130-0073-60 Safeway, 1 capsule — — FDA listed —
Gas Relief 180 mg 21130-0446-60 Safeway, 60 capsules — — FDA listed —
Ultra Strength Gas Relief 180 mg 21130-0717-06 BETTER 60 capsules — — FDA listed —
Simethicone 180 mg 35916-1939-01 SOFTGEL 1000 capsules — — Discontinued —
Gas Relief Ultra Strength 180 mg 36800-0324-05 TOPCO 25 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 37808-0874-60 H 60 capsules — — FDA listed —
Gas Relief 180 mg 41163-0773-60 United 60 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 41163-0832-60 United 60 capsules — — FDA listed —
Ultra Strength Gas Relief 180 mg 41226-0717-30 KROGER 60 capsules — — FDA listed —
Care One Gas Relief 180 mg 41520-0657-72 American 60 capsules — — FDA listed —
Ultra Strength Gas Relief 180 mg 49035-0585-21 Wal-Mart 50 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 50090-6088-00 A-S 1440 capsules — — FDA listed —
Gas Relief 180 mg 51316-0152-20 CVS 1 capsule — — FDA listed —
Ultrastrength Gas Relief 180 mg 51316-0621-76 CVS 50 capsules — — FDA listed —
Gas Relief Ultra Strength 410 180 mg 53345-0003-03 Humanwell 25000 capsules — — FDA listed —
Simethicone 180 mg 53345-0036-01 Humanwell 25000 capsules — — FDA listed —
Gas Relief 180 mg 56062-0657-72 Publix 60 capsules — — FDA listed —
Gas Relief 180 mg 59726-0152-60 P 60 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 59726-0773-20 P 1 capsule — — FDA listed —
Gas Relief 180 mg 63941-0152-60 Best 60 capsules — — FDA listed —
Anti-Gas Ultra Strength 180 mg 63941-0773-60 Best 60 capsules — — FDA listed —
good sense gas relief 180 mg 68788-4101-03 Preferred 30 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 68788-7890-03 Preferred 30 capsules — — Discontinued —
Gas Relief 180 mg 69168-0433-06 Allegiant 120 capsules — — FDA listed —
ultra strength gas relief 180 mg 69452-0543-83 BIONPHARMA 300 capsules — — FDA listed —
Gas Relief Ultra Strength 180 mg 69842-0832-20 CVS 20 capsules — — FDA listed —
Gas Relief 180 mg 70000-0668-01 CARDINAL 60 capsules — — FDA listed —
Gas Relief 180 mg 72090-0015-01 Pioneer 180 capsules — — FDA listed —
basic care gas relief 180 mg 72288-0657-72 Amazon.com 60 capsules — — FDA listed —
Curist Gas Relief 180 mg/180mg 72559-0041-48 Little 365 mg — — FDA listed —
Simethicone 180 mg 73629-0002-18 AMZ789 180 capsules — — FDA listed —
ULTRA STRENGTH Gas Relief Softgels 180 mg 76162-0840-05 Topco 25 capsules — — FDA listed —
meijer ULTRA STRENGTH Gas Relief SOFTGEL 180 mg 79481-0814-05 Meijer, 25 capsules — — FDA listed —
Gas Relief 180 mg 83455-0152-60 United 60 capsules — — FDA listed —
Gas Relief Simethicone 180mg Softgel 180 mg 84324-0015-01 NUVICARE 100 capsules — — FDA listed —
Simethicone 180 MG 85786-0401-24 Farmacias 24 capsules — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2020
On the market since
Jul 2020
📍
2026
Currently FDA-listed
6 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Simethicone inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII WZB9127XOA
    A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
  • UNII H77VEI93A8
    A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.

4 inactive ingredients listed in the exact product block matched to this NDC.

The official label also statesFD&C red #40, FD&C yellow #6, gelatin, glycerin

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerRugby Laboratories, Inc.
FDA applicationM002 (OTC MONOGRAPH DRUG)
Labeler code00536
First marketedJul 2020
Product typeHuman Otc Drug
Portfolio14 products on file

More NDCs from Rugby Laboratories, Inc. labeler code 00536

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 11 words ▾

Uses relieves bloating, pressure, or fullness commonly referred to as gas

⏱️ Dosage and Administration 26 words ▾

Directions swallow one or two softgels as symptoms occur do not exceed two softgels per 24 hours except under the advice and supervision of a physician

⚠️ Warnings 26 words ▾

Warnings Stop use and ask a doctor if condition persists. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.

📦 Storage and Handling 11 words ▾

Other information store between 15-30ºC (59-86ºF) protect from heat and moisture

🧪 Active Ingredient 8 words ▾

Active ingredient (in each softgel) Simethicone 180 mg

🧪 Inactive Ingredients 10 words ▾

Inactive ingredients FD&C red #40, FD&C yellow #6, gelatin, glycerin

🎯 Purpose 2 words ▾

Purpose Antigas

📄 Stop Use and Ask a Doctor If 9 words ▾

Stop use and ask a doctor if condition persists.

🤰 If Pregnant or Breast-Feeding 10 words ▾

If pregnant or breast-feeding, ask a health professional before use.

📄 Keep Out of Reach of Children 6 words ▾

Keep out of reach of children.

📄 Questions or Comments 5 words ▾

Questions or comments? Call 1-800-645-2158

📄 Package Label / Principal Display Panel 76 words ▾

Principal Display Panel Compare to the active ingredient in Phazyme® Ultra Strength† Ultra Strength Simethicone 180 mg Antigas Fast relief of Gas Pressure Bloating Discomfort †This product is not manufactured or distributed by C.B. Fleet Company Inc., distributor of Phazyme® Ultra Strength TAMPER EVIDENT: DO NOT USE IF PRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING Distributed by: RUGBY® LABORATORIES Livonia, MI 48152 www.rugbylaboratories.om .

Product Label RUGBY Ultra Strength Gas Relief Simethicone 180 mg

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
716
Units reimbursed last 4 qtrs
40.2K
Gross reimbursed last 4 qtrs
$5.6K
Avg / prescription
$7.76
Avg / unit
$0.1381
Latest quarter Q1 2026
48Rx
Medicaid pays / ea
$0.1381
gross reimbursed
vs
NADAC / ea
$0.0541
acquisition cost
=
Spread
+$0.0840
+155% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
33% FFS 67% MCO
Fee-for-service · 233 Rx Managed care · 483 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 828 units · 14.4 per 100k residents MN Wisconsin: no data reported WI Michigan: no data reported MI New York: no data reported NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: 823 units · 6.6 per 100k residents IL Indiana: 590 units · 8.6 per 100k residents IN Ohio: no data reported OH Pennsylvania: 298 units · 2.3 per 100k residents PA New Jersey: 666 units · 7.2 per 100k residents NJ Massachusetts: 13,121 units · 187 per 100k residents MA California: 6,664 units · 17.1 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: no data reported NE Missouri: no data reported MO Kentucky: 6,328 units · 140 per 100k residents KY West Virginia: no data reported WV Virginia: no data reported VA Maryland: no data reported MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: 3,918 units · 52.7 per 100k residents AZ New Mexico: no data reported NM Kansas: no data reported KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: 7,008 units · 23.0 per 100k residents TX Florida: no data reported FL
Units reimbursed · per 100k residents
2.3187
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Massachusetts 187 /100k
2 Kentucky 140 /100k
3 Arizona 52.7 /100k
4 Texas 23.0 /100k
5 California 17.1 /100k
6 Minnesota 14.4 /100k
7 Indiana 8.6 /100k
8 New Jersey 7.2 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
← 00536-1304-85 · RUGBY 00536-1307-23 · Rugby →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.