Gas Relief Ultra Strength Simethicone 180 mg Capsule, Liquid Filled, 60-count
by Rugby Laboratories, Inc. · 60 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0536-1306-08)
NDC 00536-1306-08
🏷️ FDA NDC (as labeled)
0536-1306-08
billing pads the labeler segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
0536-1306-08
Product NDC
0536-1306
11-digit billing NDC
00536130608
NCPDP billing unit
EA — each (per item)
RxCUI
252294
UNII
92RU3N3Y1O
UPC
0305361306083
Application #
M002
SPL Set ID
24731f4b-ca2b-483f-beed-dfc8104f8133
Physiologic effect
Skin Barrier Activity
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2020-07-24
Marketing end
2026-10-28
Route
ORAL
Dosage form
CAPSULE, LIQUID FILLED
Substance
DIMETHICONE
GPI-14
52200020000135
GPI class
Simethicone Ultra Strength
GCN Seq No
040944
GCN
94652
HICL code
001224
Ingredient (HICL)
Simethicone
HIC1 code
D
Therapeutic class — broad (HIC1)
Biliary System/Gastro-Intestinal System
HIC2 code
D4
Therapeutic class — intermediate (HIC2)
Drugs Acting Principally On The Alimentary Tract
HIC3 code
D4N
Therapeutic class — specific (HIC3)
Antiflatulents
AHFS code
56:10.00.00
AHFS class
Antiflatulents
FDB label name
SIMETHICONE 180 MG SOFTGEL
FDB brand name
Simethicone
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 0536-1306-08 — a 4-4-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the labeler segment → 00536-1306-08. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerRugby Laboratories, Inc.
FDA applicationM002 (OTC MONOGRAPH DRUG)
Labeler code00536
First marketedJul 2020
Product typeHuman Otc Drug
Portfolio14 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name SIMETHICONE 180 MG SOFTGEL Ingredient Simethicone
📖 What it is MedlinePlus · NLM
Simethicone is used to treat the symptoms of gas such as uncomfortable or painful pressure, fullness, and bloating. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- Simethicone works to relieve the uncomfortable pressure, bloating, and full or stuffed feeling that comes from trapped gas in your stomach or intestines. It's used when gas builds...
- What exactly does simethicone do for gas?
- Yes — there are infant-specific simethicone products, like Mylicon Infants Gas Relief and similar infant drops, designed just for babies. They're used to relieve gas discomfort tha...
- Can I give simethicone drops to my baby?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Simethicone — tap one for details:
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Simethicone?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
orange
ShapeCapsule
Imprint05A
Size12 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII WZB9127XOA
A synthetic red dye used to color medications and make them easier to identify. It serves as a colorant in tablets, capsules, and liquid formulations.
-
UNII H77VEI93A8
A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
-
UNII 2G86QN327L
Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
4 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesFD&C red #40, FD&C yellow #6, gelatin, glycerin
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per ea | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.053 | $3.18 / 60 capsules |
| Medicaid paysCMS SDUD · 12 mo | $0.1441 | $8.65 / 60 capsules |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per ea) — tap or hover for the price & month
▼ Down 17% over the last 24 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| good sense gas relief 180 mg 00113-0657-72 | L. | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief Ultra Strength 180 mgthis 00536-1306-08 | Rugby | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 00536-1421-08 | Rugby | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 46122-0769-64 | AmerisourceBergen | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 70677-1093-01 | Strategic | 60 capsules | $0.053 | — | Availability likely | — |
| Phazyme 180 mg 00132-0208-12 | C.B. | 12 capsules | $0.228 | — | FDA listed | +330% |
| Gas-X Ultra Strength AntiGas Softgels 180 mg 00067-6274-18 | Haleon | 9 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-0833-50 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-0932-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 00363-1510-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-8730-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-8740-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 00363-9941-09 | Walgreen | 10 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 00363-9942-22 | Walgreen | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 21130-0073-60 | Safeway, | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 21130-0446-60 | Safeway, | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 21130-0717-06 | BETTER | 60 capsules | — | — | FDA listed | — |
| Simethicone 180 mg 35916-1939-01 | SOFTGEL | 1000 capsules | — | — | Discontinued | — |
| Gas Relief Ultra Strength 180 mg 36800-0324-05 | TOPCO | 25 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 37808-0874-60 | H | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 41163-0773-60 | United | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 41163-0832-60 | United | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 41226-0717-30 | KROGER | 60 capsules | — | — | FDA listed | — |
| Care One Gas Relief 180 mg 41520-0657-72 | American | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 49035-0585-21 | Wal-Mart | 50 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 50090-6088-00 | A-S | 1440 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 51316-0152-20 | CVS | 1 capsule | — | — | FDA listed | — |
| Ultrastrength Gas Relief 180 mg 51316-0621-76 | CVS | 50 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 410 180 mg 53345-0003-03 | Humanwell | 25000 capsules | — | — | FDA listed | — |
| Simethicone 180 mg 53345-0036-01 | Humanwell | 25000 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 56062-0657-72 | Publix | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 59726-0152-60 | P | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 59726-0773-20 | P | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 63941-0152-60 | Best | 60 capsules | — | — | FDA listed | — |
| Anti-Gas Ultra Strength 180 mg 63941-0773-60 | Best | 60 capsules | — | — | FDA listed | — |
| good sense gas relief 180 mg 68788-4101-03 | Preferred | 30 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 68788-7890-03 | Preferred | 30 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 69168-0433-06 | Allegiant | 120 capsules | — | — | FDA listed | — |
| ultra strength gas relief 180 mg 69452-0543-83 | BIONPHARMA | 300 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 69842-0832-20 | CVS | 20 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 70000-0668-01 | CARDINAL | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 70677-1254-01 | Strategic | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 72090-0015-01 | Pioneer | 180 capsules | — | — | FDA listed | — |
| basic care gas relief 180 mg 72288-0657-72 | Amazon.com | 60 capsules | — | — | FDA listed | — |
| Curist Gas Relief 180 mg/180mg 72559-0041-48 | Little | 365 mg | — | — | FDA listed | — |
| Simethicone 180 mg 73629-0002-18 | AMZ789 | 180 capsules | — | — | FDA listed | — |
| ULTRA STRENGTH Gas Relief Softgels 180 mg 76162-0840-05 | Topco | 25 capsules | — | — | FDA listed | — |
| meijer ULTRA STRENGTH Gas Relief SOFTGEL 180 mg 79481-0814-05 | Meijer, | 25 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 83455-0152-60 | United | 60 capsules | — | — | FDA listed | — |
| Gas Relief Simethicone 180mg Softgel 180 mg 84324-0015-01 | NUVICARE | 100 capsules | — | — | FDA listed | — |
| Simethicone 180 MG 85786-0401-24 | Farmacias | 24 capsules | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2020
On the market since
Jul 2020
📍
2026
Currently FDA-listed
6 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🗺️ Medicaid utilization & spend
📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for 00536-1306-08, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q4 2025 · 4 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
1.2K
Units reimbursed last 4 qtrs
63.9K
Gross reimbursed last 4 qtrs
$9.2K
Avg / prescription
$7.76
Avg / unit
$0.1441
Latest quarter Q4 2025
61Rx
Medicaid pays / ea
$0.1441
gross reimbursed
vs
NADAC / ea
$0.0530
acquisition cost
=
Spread
+$0.0911
+172% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
Fee-for-service · 394 Rx Managed care · 792 Rx
State Medicaid map
Units reimbursed · per 100k residents
4.5272
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
Prescriptions—
Units—
Reimbursed—
🏆 Top states by units · per 100k residents
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Gas Relief Ultra Strength (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 46%
Female · 53%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 00536-1306-08 You're viewing this | 60 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (0536-1306-08) | 2020-07-24 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses relieves bloating, pressure, or fullness commonly referred to as gas
⏱️ Dosage and Administration ▾
Directions swallow one or two softgels as symptoms occur do not exceed two softgels per 24 hours except under the advice and supervision of a physician
⚠️ Warnings ▾
Warnings Stop use and ask a doctor if condition persists. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.
📦 Storage and Handling ▾
Other information store between 15-30ºC (59-86ºF) protect from heat and moisture
🧪 Active Ingredient ▾
Active ingredient (in each softgel) Simethicone 180 mg
🧪 Inactive Ingredients ▾
Inactive ingredients FD&C red #40, FD&C yellow #6, gelatin, glycerin
🎯 Purpose ▾
Purpose Antigas
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.