Ultra Strength Gas Relief Simethicone 180 mg Capsule, 60-count
by KROGER COMPANY · 1 BOTTLE in 1 CARTON (41226-717-30) / 60 CAPSULE in 1 BOTTLE
NDC 41226-0717-30
🏷️ FDA NDC (as labeled)
41226-717-30
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
41226-717-30
Product NDC
41226-717
11-digit billing NDC
41226071730
RxCUI
252294
UNII
92RU3N3Y1O
UPC
0041260018435
Application #
M002
SPL Set ID
ea1c4aa8-bde6-2072-e053-2995a90a93ba
Physiologic effect
Skin Barrier Activity
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2023-05-05
Route
ORAL
Dosage form
CAPSULE
Substance
DIMETHICONE
Why two NDCs?
The FDA registers this code as 41226-717-30 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 41226-0717-30. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerKROGER COMPANY
FDA applicationM002 (OTC MONOGRAPH DRUG)
Labeler code41226
First marketedMay 2023
Product typeHuman Otc Drug
Portfolio261 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
📖 What it is MedlinePlus · NLM
Simethicone is used to treat the symptoms of gas such as uncomfortable or painful pressure, fullness, and bloating. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- Simethicone works to relieve the uncomfortable pressure, bloating, and full or stuffed feeling that comes from trapped gas in your stomach or intestines. It's used when gas builds...
- What exactly does simethicone do for gas?
- Yes — there are infant-specific simethicone products, like Mylicon Infants Gas Relief and similar infant drops, designed just for babies. They're used to relieve gas discomfort tha...
- Can I give simethicone drops to my baby?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Simethicone — tap one for details:
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Simethicone?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
orange
ShapeOval
Imprint104
Size11 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII H77VEI93A8
A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
-
UNII 2G86QN327L
Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
-
UNII C9H2L21V7U
A fat derived from coconut or palm oil containing shorter fatty acid chains. It serves as a solvent and carrier to help dissolve or suspend active ingredients, improving absorption and stability in liquid formulations.
-
UNII AV092KU4JH
A natural oil extracted from peppermint plants. It's used as a flavoring agent to mask bitter tastes and add a refreshing mint flavor to medicines, making them easier to take.
-
UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
-
UNII 46N107B71O
Shellac is a natural resin secreted by the lac beetle. It's used as a coating on tablets and capsules to control how quickly the medicine dissolves and to improve appearance and stability.
-
UNII 6O92ICV9RU
A waxy substance derived from sorbitol that helps mix oil and water together in medicines. It's used as an emulsifier to keep ingredients evenly blended and stable.
-
UNII 8KW3E207O2
A liquid sweetener made from sorbitol, a sugar alcohol derived from glucose. It sweetens the medicine and also acts as a humectant to help retain moisture and improve texture in liquid formulations.
-
UNII 15FIX9V2JP
Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
11 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesInactive ingredients FD&C Yellow No. 6, gelatin, glycerol, medium chain triglyceride, peppermint oil, propylene glycol, purified water, shellac, sorbitol sorbitan solution, titanium dioxide
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| good sense gas relief 180 mg 00113-0657-72 | L. | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief Ultra Strength 180 mg 00536-1306-08 | Rugby | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 00536-1421-08 | Rugby | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 46122-0769-64 | AmerisourceBergen | 60 capsules | $0.053 | — | Availability likely | — |
| Gas Relief 180 mg 70677-1093-01 | Strategic | 60 capsules | $0.053 | — | Availability likely | — |
| Phazyme 180 mg 00132-0208-12 | C.B. | 12 capsules | $0.228 | — | FDA listed | — |
| Gas-X Ultra Strength AntiGas Softgels 180 mg 00067-6274-18 | Haleon | 9 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-0833-50 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-0932-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 00363-1510-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-8730-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 00363-8740-20 | Walgreens | 1 capsule | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 00363-9941-09 | Walgreen | 10 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 00363-9942-22 | Walgreen | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 21130-0073-60 | Safeway, | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 21130-0446-60 | Safeway, | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 21130-0717-06 | BETTER | 60 capsules | — | — | FDA listed | — |
| Simethicone 180 mg 35916-1939-01 | SOFTGEL | 1000 capsules | — | — | Discontinued | — |
| Gas Relief Ultra Strength 180 mg 36800-0324-05 | TOPCO | 25 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 37808-0874-60 | H | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 41163-0773-60 | United | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 41163-0832-60 | United | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mgthis 41226-0717-30 | KROGER | 60 capsules | — | — | FDA listed | — |
| Care One Gas Relief 180 mg 41520-0657-72 | American | 60 capsules | — | — | FDA listed | — |
| Ultra Strength Gas Relief 180 mg 49035-0585-21 | Wal-Mart | 50 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 50090-6088-00 | A-S | 1440 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 51316-0152-20 | CVS | 1 capsule | — | — | FDA listed | — |
| Ultrastrength Gas Relief 180 mg 51316-0621-76 | CVS | 50 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 410 180 mg 53345-0003-03 | Humanwell | 25000 capsules | — | — | FDA listed | — |
| Simethicone 180 mg 53345-0036-01 | Humanwell | 25000 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 56062-0657-72 | Publix | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 59726-0152-60 | P | 60 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 59726-0773-20 | P | 1 capsule | — | — | FDA listed | — |
| Gas Relief 180 mg 63941-0152-60 | Best | 60 capsules | — | — | FDA listed | — |
| Anti-Gas Ultra Strength 180 mg 63941-0773-60 | Best | 60 capsules | — | — | FDA listed | — |
| good sense gas relief 180 mg 68788-4101-03 | Preferred | 30 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 68788-7890-03 | Preferred | 30 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 69168-0433-06 | Allegiant | 120 capsules | — | — | FDA listed | — |
| ultra strength gas relief 180 mg 69452-0543-83 | BIONPHARMA | 300 capsules | — | — | FDA listed | — |
| Gas Relief Ultra Strength 180 mg 69842-0832-20 | CVS | 20 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 70000-0668-01 | CARDINAL | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 70677-1254-01 | Strategic | 60 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 72090-0015-01 | Pioneer | 180 capsules | — | — | FDA listed | — |
| basic care gas relief 180 mg 72288-0657-72 | Amazon.com | 60 capsules | — | — | FDA listed | — |
| Curist Gas Relief 180 mg/180mg 72559-0041-48 | Little | 365 mg | — | — | FDA listed | — |
| Simethicone 180 mg 73629-0002-18 | AMZ789 | 180 capsules | — | — | FDA listed | — |
| ULTRA STRENGTH Gas Relief Softgels 180 mg 76162-0840-05 | Topco | 25 capsules | — | — | FDA listed | — |
| meijer ULTRA STRENGTH Gas Relief SOFTGEL 180 mg 79481-0814-05 | Meijer, | 25 capsules | — | — | FDA listed | — |
| Gas Relief 180 mg 83455-0152-60 | United | 60 capsules | — | — | FDA listed | — |
| Gas Relief Simethicone 180mg Softgel 180 mg 84324-0015-01 | NUVICARE | 100 capsules | — | — | FDA listed | — |
| Simethicone 180 MG 85786-0401-24 | Farmacias | 24 capsules | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2023
On the market since
May 2023
📍
2026
Currently FDA-listed
3 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Ultra Strength Gas Relief (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 49%
Female · 51%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 41226-0717-30 You're viewing this | 1 BOTTLE in 1 CARTON (41226-717-30) / 60 CAPSULE in 1 BOTTLE | 2023-05-05 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 41226-717-30, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 41226-0717-30, written without dashes as 41226071730. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 41226-0717-30, the first segment (41226) is the labeler code FDA assigned to KROGER COMPANY; the middle segment (0717) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (30) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by KROGER COMPANY. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
KROGER COMPANY is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses • Relieves bloating, pressure or fullness commonly referred to as gas.
⏱️ Dosage and Administration ▾
Directions • Swallow one or two softgels as symptoms occur. • Do not exceed two softgels per 24 hours except under the advice and supervision of a physician.
⚠️ Warnings ▾
Warnings Stop use and ask a doctor if condition persists. Keep out of reach of children.
📦 Storage and Handling ▾
Other information • Store at room temperature
🧪 Active Ingredient ▾
Active ingredient (in each softgel) Simethicone 180 mg
🧪 Inactive Ingredients ▾
Inactive ingredients FD&C Yellow No. 6, gelatin, glycerol, medium chain triglyceride, peppermint oil, propylene glycol, purified water, shellac, sorbitol sorbitan solution, titanium dioxide
🎯 Purpose ▾
Purpose Anti-gas
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.