Olopatadine Hydrochloride 2 mg/mL Solution/ Drops, 1 bottle — NDC 0536-1307-23 (Billing 00536-1307-23)
This is a package of 1 bottle of Olopatadine Hydrochloride 2 mg/mL Solution/ Drops from Rugby Laboratories, marketed since Jan 2021 and currently FDA-listed; retail pharmacies pay about $2.96 per mL (NADAC). It is this product's only package size.
NDC database record
One package, one record: these facts belong to NDC 0536-1307-23 alone.
- Record
- FDA NDC Directory package listing · Human OTC drug
- Code segments
- 0536 labeler · 1307 product · 23 package
- Package marketed since
- Jan 15, 2021
- Sample package
- No — commercial package
- Listing certified through
- Dec 31, 2027
- Barcode (UPC-A, from the NDC)
- 3 0536130723 3
- Medicaid fills, this package
- 71,262 prescriptions in the last four reported quarters
- FDA record last changed
- Jul 24, 2026
Identity & classification
Regulatory identifiers FDA, NLM and CMS codes for this package
Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification
- GSN (GCN sequence number): 062065
- GCN: 97848
- GPI-14 (Medi-Span): 86802065102030
- HICL (First Databank): 012815
- AHFS class code: 52:02.00.00
- RxCUI (RxNorm): 1111343
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
- RxNorm (NLM RxNav) · catalog refreshed Oct 1, 2026
- Medi-Span GPI (licensed)
- First Databank (licensed) · refreshed Oct 1, 2026
RxNorm drug class
This medicine belongs to the Histamine-1 Receptor Inhibitor class.
Where does this data come from?
- RxClass (NLM) · catalog refreshed Oct 1, 2026
Clinical
Prescription ophthalmic olopatadine (Pazeo) and nonprescription ophthalmic olopatadine (Pataday) are used to relieve itchy eyes caused by allergic reactions to pollen, ragweed, grass, animal hair, or pet dander. Olopatadine is in a class of medications called mast cell stabilizers. It works by preventing the release of substances that cause eye itching.
Read the full MedlinePlus article ↗- The eye drops relieve itchy eyes from allergies, and some products relieve redness too. The nasal spray relieves seasonal allergic rhinitis symptoms in adults and children 6 and ol...
- It depends on the product. Some eye drops are twice daily, 6 to 8 hours apart, and others once daily. The nasal spray is twice daily. Follow your label or prescriber.
- Take your lenses out before using the drops and wait at least 10 minutes before putting them back. Don't wear lenses if your eyes are red. These drops aren't for contact lens irrit...
- With the nasal spray, a bitter taste, headache, nosebleeds and sore throat are common. It can also make you drowsy, so be careful driving and skip alcohol.
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Olopatadine Hydrochloride — tap one for details:
Where does this data come from?
- MedlinePlus (NLM) · refreshed Oct 1, 2026
- FDA label on DailyMed · label index refreshed Oct 5, 2026
Ask a licensed pharmacist directly — free, answered by our team.
Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $2.964 | $7.41 / 2.5 ml |
| Medicaid paysCMS SDUD · 12 mo | $6.36 | $15.90 / 2.5 ml |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
- CMS NADAC weekly file · file of Sep 30, 2026
- CMS ASP pricing files · refreshed Sep 20, 2026
- CMS Medicaid State Drug Utilization Data · through Q4 2025
- CMS Part D plan pricing files · refreshed Sep 24, 2026
- VA National Acquisition Center price file
Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Marketing end | Status |
|---|---|---|---|---|
| 00536-1307-23 You're viewing this Main listing | 1 BOTTLE, PLASTIC in 1 CARTON / 2.5 mL in 1 BOTTLE, PLASTIC | 2021-01-15 | — | Active |
Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Olopatadine Hydrochloride 2 mg/mL 24208-0617-01 | Bausch | 1 bottle | $1.983 | — | Availability likely | save 33% |
| Leader Olopatadine Hydrochloride 2 mg/mL 70000-0716-01 | CARDINAL | 1 bottle | $1.983 | — | Availability likely | save 33% |
| Olopatadine Hydrochloride 2 mg/mLthis 00536-1307-23 | Rugby | 1 bottle | $2.964 | — | Availability likely | — |
| olopatadine hydrochloride 2 mg/mL 16571-0861-25 | Rising | 2.5 ml | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 43598-0764-02 | Dr. | 1 bottle | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride 2 mg/mL 46122-0671-27 | Amerisource | 1 bottle | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride 2 mg/mL 68001-0530-69 | BluePoint | 1 bottle | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride 2 mg/mL 68001-0674-92 | BluePoint | 1 bottle | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride 2 mg/mL 70069-0491-01 | Somerset | 1 bottle | $2.964 | — | Availability likely | — |
| Eye Allergy Itch Relief Once Daily Relief 2 mg/mL 70677-1155-01 | Strategic | 1 bottle | $2.964 | — | Availability likely | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 83324-0120-25 | Chain | 1 bottle | $2.964 | — | Availability likely | — |
| Eye Allergy Itch Relief 2 mg/mL 70000-0053-01 | CARDINAL | 1 bottle | $3.096 | — | Availability likely | +4% |
| Pataday Once Daily Relief 2 mg/mL 00065-8150-01 | Alcon | 1 bottle | $5.893 | — | Availability likely | +99% |
| Olopatadine Hydrochloride 2 mg/mL 00363-0869-01 | WALGREEN | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 00363-7131-25 | Walgreens | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 00363-8022-39 | WALGREEN | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 11673-0688-25 | Target | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 11822-0063-02 | RITE | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 11822-9975-02 | Rite | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 21130-0105-02 | Albertsons | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 24208-0967-01 | Bausch | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 30142-0026-27 | Kroger | 1 bottle | — | — | FDA listed | — |
| Once Daily Relief 2 mg/mL 37808-0045-25 | H | 1 bottle | — | — | FDA listed | — |
| Eye Allergy Itch Relief Once Daily Relief 2 mg/mL 43598-0827-02 | Dr. | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 46122-0824-29 | AmerisourceBergen | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 46708-0710-03 | Alembic | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 50090-5613-00 | A-S | 1 bottle | — | — | FDA listed | — |
| Allergy Relief Eye Drops 2 mg/mL 51316-0675-25 | CVS | 1 bottle | — | — | FDA listed | — |
| Retaine Allergy 5 mg/2.5mL 54799-0920-25 | OCuSOFT | 2.5 ml | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution Once Daily 2 mg/mL 55910-0137-25 | DOLGENCORP, | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 58602-0007-39 | Aurohealth | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 58602-0010-39 | Aurohealth | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 58602-0013-39 | Aurohealth | 1 bottle | — | — | FDA listed | — |
| Olopatadine hydrochloride 2 mg/mL 60505-6222-02 | Apotex | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 62332-0502-03 | Alembic | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 62332-0710-03 | Alembic | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 63868-0821-25 | Chain | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 63941-0024-39 | Best | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic 2 mg/mL 68083-0231-01 | Gland | 1 bottle | — | — | FDA listed | — |
| Eye Allergy Itch Relief 2 mg/mL 69168-0495-77 | Allegiant | 2 bottles | — | — | FDA listed | — |
| CVS Eye Allergy Itch Relief Once Daily 2 mg/mL 69842-0269-25 | CVS | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 72036-0009-39 | Harris | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 72476-0851-21 | Retail | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 72657-0194-11 | GLENMARK | 2 bottles | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 73581-0709-02 | YYBA | 2 bottles | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 76162-0044-39 | TOPCO | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 79481-1001-02 | Meijer | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 79903-0001-39 | Wal-Mart | 1 bottle | — | — | FDA listed | — |
| Equate Olopatadine Hydrochloride 2 mg/mL 79903-0318-01 | WAL-MART | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 80539-0001-39 | Allwell | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride Ophthalmic Solution 2 mg/mL 82442-0967-02 | TARGET | 1 bottle | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 73581-0712-02 | YYBA | 2 bottles | — | — | FDA listed | — |
| Olopatadine Hydrochloride 2 mg/mL 73581-0713-02 | YYBA | 2 bottles | — | — | FDA listed | — |
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- FDA Orange Book · refreshed Oct 3, 2026
- CMS NADAC weekly file · file of Sep 30, 2026
Availability & generic status
This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.
Where does this data come from?
- FDA Orange Book · refreshed Oct 3, 2026
Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
🧪 Avoiding an ingredient? See Olopatadine inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.
Where does this data come from?
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.- FDA label on DailyMed · label index refreshed Oct 5, 2026
- FDA openFDA NDC Directory · synced Oct 1, 2026
Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
Manufacturer & labeler
More NDCs from Rugby Laboratories labeler code 00536
- Rugby Famotidine 20 mg Tablet, Film Coated NDC 0536-1298-01
- Meclizine Hydrochloride 25 mg Tablet, Chewable NDC 0536-1299-01
- Anti Nausea dextrose(glucose),Levulose(fructose),Phosphoric acid 1.87 g/5mL; 1.87 g/5mL; 21.5 mg/5mL Liquid NDC 0536-1302-97
- Infants Simethicone 20 mg/.3mL Suspension/ Drops NDC 0536-1303-75
- Docusate Sodium Liquid 50 mg/5mL Liquid NDC 0536-1304-85
- Gas Relief Ultra Strength Simethicone 180 mg Capsule, Liquid Filled NDC 0536-1306-08
- Olopatadine Hydrochloride Ophthalmic Solution 1 mg/mL Solution/ Drops NDC 0536-1308-40
- Rugby Chest Congestion Relief PE Guaifenesin/phenylephrine 400 mg; 10 mg Tablet NDC 0536-1309-07
- Rugby Chest Congestion Relief G450 Guaifenesin 400 mg Tablet NDC 0536-1311-08
- Rugby Chest Congestion Relief DM Dextromethorphan Hydrobromide / Guaifenesin 20 mg; 400 mg Tablet NDC 0536-1312-08
- Chest Congestion Relief DM Dextromethorphan Hydrobromide, Guaifenesin 10 mg/5mL; 100 mg/5mL Liquid NDC 0536-1313-85
- Chest Congestion Relief Guaifenesin 100 mg/5mL Liquid NDC 0536-1314-85
Where does this data come from?
- FDA openFDA NDC Directory · synced Oct 1, 2026
- Drugs@FDA
FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
USE temporarily relieves itchy eyes due to pollen, ragweed, grass, animal hair and dander
⏱️ Dosage and Administration ▾
DIRECTIONS adults and children 2 years of age and older: put 1 drop in the affected eye(s) once daily, no more than once per day if using other ophthalmic products while using this product, wait at least 5 minutes between each product replace cap after each use children under 2 years of age: consult a doctor
⚠️ Warnings ▾
WARNINGS For external use only
🧪 Active Ingredient ▾
ACTIVE INGREDIENT Olopatadine (0.2%) (equivalent to olopatadine hydrochloride 0.222%)
🧪 Inactive Ingredients ▾
INACTIVE INGREDIENTS Benzalkonium chloride 0.01%, Dibasic sodium phosphate, Edetate disodium, Hydrochloric acid/Sodium hydroxide (adjust pH), Povidone, Sodium chloride, and Water for Injection.
🎯 Purpose ▾
PURPOSE Antihistamine
📄 Do Not Use ▾
DO NOT USE if solution changes color or becomes cloudy if you are sensitive to any ingredient in this product to treat contact lens related irritation
📄 When Using This Product ▾
WHEN USING THIS PRODUCT do not touch tip of container to any surface to avoid contamination remove contact lenses before use wait at least 10 minutes before reinserting contact lenses after use do not wear a contact lens if your eye is red
📄 Stop Use and Ask a Doctor If ▾
STOP USE AND ASK DOCTOR IF you experience: eye pain changes in vision increased redness of the eye itching worsens or lasts for more than 72 hours
📄 Keep Out of Reach of Children ▾
KEEP OUT OF REACH OF CHILDREN If swallowed, get medical help or contact a Poison Control Center right away.
📄 Package Label / Principal Display Panel ▾
PRINCIPAL DISPLAY PANEL NDC 0536-1307-23 Olopatadine HCl Ophthalmic Solution USP, 0.2% antihistamine once daily eye allergy itch relief original prescription strength works in minutes relief from allergens: • pet dander • pollen • grass • ragweed 2.5 mL (0.085 FL OZ) sterile Compare to active ingredient in Pataday Once Daily Relief* Packaged with Tamper-Evident bottle cap. Do Not Use if breakable ring is separated or missing. For Ages 2 and Older 30 DAY SUPPLY