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up and up medicated wipes manixim strength gentle hemorrhoidal care .5 g/g Swab, 48 applicators — NDC 11673-0404-48 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

up and up medicated wipes manixim strength gentle hemorrhoidal care .5 g/g Swab, 48 applicators — NDC 11673-404-48 (Billing 11673-0404-48)

by Target Corporation · 48 APPLICATOR in 1 CELLO PACK / 5.375 g in 1 APPLICATOR

This is a package of 48 applicators of up and up medicated wipes manixim strength gentle hemorrhoidal care .5 g/g Swab from Target Corporation, marketed since Jan 2015 and currently FDA-listed. It is the main listing for this product, which comes in 2 package sizes.

NDC 11673-0404-48
🏷️ FDA NDC (as labeled) 11673-404-48 billing pads the product segment with a zero
This package
Contains48 applicators Pack sizes2 compare ↓
Main listing for product 11673-404 · Also comes in: 2 cellos 11673-404-96
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Sep 17, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 11673-404-48
Product NDC 11673-404
11-digit billing NDC 11673040448
RxCUI 844379
UNII 101I4J0U34
Application # M015
SPL Set ID 271eab2b-ed13-39f1-e054-00144ff88e88
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2015-01-01
Route TOPICAL
Dosage form SWAB
Substance WITCH HAZEL
Quick answers
  • RxCUI (RxNorm): 844379
Why two NDCs? The FDA registers this code as 11673-404-48 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 11673-0404-48. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is a topical swab product containing witch hazel, marketed as an over-the-counter hemorrhoidal care wipe under FDA's monograph rules for external hemorrhoidal products. Witch hazel is typically used in hemorrhoidal preparations for its astringent properties, which are believed to help reduce swelling and soothe irritated tissue in the rectal area. The swab format allows for direct topical application to affected areas.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 2 cellos
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
11673-0404-48 You're viewing this Main listing 48 APPLICATOR in 1 CELLO PACK / 5.375 g in 1 APPLICATOR 2015-01-01 — Active
11673-0404-96 11673-404-96 2 CELLO PACK in 1 CARTON / 48 APPLICATOR in 1 CELLO PACK / 5.375 g in 1 APPLICATOR 2019-04-03 — Active

Pack size FAQ

What quantity is in this package?
This package contains 48 applicators — 48 applicator in 1 cello pack / 5.375 g in 1 applicator.
What NDC number is used to bill for this package of up and up medicated wipes manixim strength gentle hemorrhoidal care .5 g/g Swab?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Major Medi-Pads 50 g/100g 00904-6829-60 Major 100 packets $0.044 — Availability likely —
Medicated Hemorrhoidal Pads 500 mg/mL 70000-0364-01 Cardinal 1 jar $0.044 — Availability likely —
QC Medicated Cooling 500 mg 83324-0311-01 Chain 1 jar $0.044 — Availability likely —
Pre-moistened Medicated Wipes, Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent, Walgreens Pre-moistened Medicated Wipes, Walgreens Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent 50 mg/100mg 00363-1740-48 Walgreens 48 patches — — FDA listed —
Preparation H Medicated Wipes 5 g 00573-0556-07 Haleon 10 packets — — FDA listed —
Preparation H Medicated Wipes 5 g 00573-0557-01 Haleon 48 cloths — — FDA listed —
Preparation H Totables Irritation Relief Wipes 5 g 00573-0558-07 Haleon 10 packets — — FDA listed —
Tucks Medicated Cooling Pads 500 mg/mL 10157-2103-01 Blistex 1 jar — — FDA listed —
up and up medicated wipes manixim strength .5 g/gthis 11673-0404-48 Target 48 applicators — — FDA listed —
medicated pads 50 mg/100mg 11673-0614-10 TARGET 100 patches — — FDA listed —
Signature Care Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 mg/mL 21130-0800-48 Better 252 ml — — FDA listed —
Signature Care Medicated Cooling 500 mg 21130-0928-00 Better 100 cloths — — FDA listed —
Kroger Medicated Wipes Hemorrhoidal Wipe With Witch Hazel And Aloe .5 g/g 30142-0791-71 The 252 g — — FDA listed —
hemorrhoidal pads 500 mg/1000mg 41250-0868-10 Meijer 100 patches — — FDA listed —
medicated wipes 500 mg/1000mg 41250-0988-48 Meijer 48 patches — — FDA listed —
Maximum Strength Hemorrhoidal Pads 500 mg 49035-0465-10 Walmart, 100 cloths — — FDA listed —
Equate Hemorrhoidal Medicated Wipes .5 mg/mL 49035-0793-41 Walmart 252 ml — — FDA listed —
AER Pre-moistened Witch Hazel Pad 500 mg/mL 50289-3250-01 Birchwood 40 applicators — — FDA listed —
AER Traveler Towelette .5 g 50289-4200-01 Birchwood 50 packets — — FDA listed —
B-SURE Traveler Towelette .5 g/g 50289-9250-01 Birchwood 4 g — — FDA listed —
Good Sense Medicated 500 mg 50804-0047-60 Geiss, 100 cloths — — FDA listed —
GOODSENSE Maximum Strength Medicated 50 g/100g 50804-0211-48 GEISS, 48 packets — — FDA listed —
Perineal Cooling Liners 500 mg/g 51316-0716-00 CVS 24 patches — — FDA listed —
TN Dickinsons Witch Hazel Hemorrhoidal Pads 1.2 g 52651-0003-01 Dickinson 1 jar — — FDA listed —
T.N. Dickinsons Witch Hazel Medicated Cooling Pads Hemorrhoidal Relief .034 g 52651-0010-01 Dickinson 1 jar — — FDA listed —
The Pharma-C Company Medicated Hemorrhoidal Pads 500 mg/mL 55239-0359-00 Kleen 100 patches — — FDA listed —
Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 55319-0402-00 FAMILY 48 patches — — Discontinued —
FAMILY Wellness MEDICATED HEMORRHOIDAL WIPES 50 g/100mL 55319-0774-01 Family 1 pouch — — FDA listed —
Rexall Medicated WipesHemorrhoidal wipe Hemorrhoidal wipes with witch hazel 129 g/258g 55910-0105-48 Old 258 g — — FDA listed —
Witch Hazel 50 g/1001 56194-0550-01 Giant 48 cloths — — FDA listed —
Geri Care Medicated Pads 50 mg/mL 57896-0115-01 Geri-Care 100 patches — — FDA listed —
Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 g/g 59779-0607-10 CVS 48 applicators — — FDA listed —
CVS Health Medicated 500 mg 59779-0747-01 CVS 1 jar — — FDA listed —
Meicated Wipe 50 g/100g 64709-0120-01 Diamond 195.09 g — — FDA listed —
Dr Talbots Cooling Perineal Pad .5 g/g 70797-0104-01 Talbot's 120 g — — FDA listed —
Dr Butlers Hemorrhoid 50 g/100g 70942-0100-48 Beyond 3 g — — FDA listed —
Hemorrhoidal Hygiene pads 50 g/100mL 71399-0110-01 Akron 175 ml — — FDA listed —
Flushable Hemorrhoidal Medicated Wipes Maximum Strength .5 g 72288-0923-01 Amazon.com 48 cloths — — FDA listed —
frida mom Perineal Cooling Pad Liners .5 g 72705-0100-01 Fridababy, 24 cloths — — FDA listed —
Perineal Cooling Pad Liners 50 g/100g 72705-0420-01 Fridababy, 100 g — — FDA listed —
Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 72932-0009-00 Wuhan 48 patches — — FDA listed —
Medicated Multipurpose Wipes 50 mg/100mg 78691-0050-15 QUEST 15 patches — — FDA listed —
Soothing Hemorrhoidal Wipes 50 Witch Hazel 500 mg/mL 82637-0059-01 The 30 patches — — FDA listed —
Pura 50 mg 84217-0050-48 Mypura.com 48 patches — — FDA listed —
Norms Medicated Wipes .5 g/g 85996-0001-01 Totally 1 g — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2015
On the market since
Jan 2015
📍
2026
Currently FDA-listed
11 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII ZY81Z83H0X
    Aloe vera leaf is a plant extract derived from the aloe plant. It is used in medicines as a natural moisturizer and skin-soothing agent in topical formulations.
  • UNII XF417D3PSL
    Anhydrous citric acid is a sour, crystalline powder derived from citric acid with water removed. In medicines, it acts as a buffer to control pH, adds tartness to improve taste, and helps tablets disintegrate.
  • UNII 6PU1E16C9W
    Bronopol is a synthetic antimicrobial preservative used in liquid and semi-solid medicines to prevent the growth of bacteria and fungi, helping keep the product safe and stable throughout its shelf life.
  • UNII 18L9G3U51M
    A gentle cleansing agent derived from coconut oil. It acts as a surfactant and emulsifier, helping mix oil and water-based ingredients together and improve how the product spreads or cleanses on skin.
  • UNII PDC6A3C0OX
    Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
  • UNII 603P14DHEB
    A synthetic antimicrobial chemical used as a preservative in topical and cosmetic formulations. It prevents bacterial and fungal growth in products to maintain stability and safety during storage and use.
  • UNII 09179OX7TB
    PEG-75 Lanolin is a waxy substance derived from sheep's wool that has been chemically modified to mix easily with water and oil. It acts as an emulsifier and moisturizer in topical formulations, helping blend different ingredients and soften the skin.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 1Q73Q2JULR
    Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
  • UNII 059QF0KO0R
    Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.

10 inactive ingredients listed in the exact product block matched to this NDC.

The official label also states2-Bromo-2-Nitropropane-1,3-Diol, Aloe Barbadensis Leaf Juice, Citric Acid, Disodium Cocoamphodiacetate, Glycerin, Iodopropynyl Butylcarbamate, PEG-75 Lanolin, Propylene Glycol, Sodium Citrate, Water

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerTarget Corporation
FDA applicationM015 (OTC MONOGRAPH DRUG)
Labeler code11673
First marketedJan 2015
Product typeHuman Otc Drug
Portfolio409 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🤒 Adverse Reactions 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Other Information 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 23 words ▾

Uses helps relieve the local itching and discomfort associated with hemorrhoids temporary relief of irritation and burning aids in protecting irritated anorectal areas

⏱️ Dosage and Administration 54 words ▾

Directions adult: unfold wipe and cleanse the area by gently wiping, patting or blotting. If necessary, repeat until all matter is removed from the area. Use up to 6 times daily or after each bowel movement and before applying topical hemorrhoidal treatments, and then discard children under 12 years of age: consult a doctor

⚠️ Warnings 5 words ▾

Warnings For external use only

🤒 Adverse Reactions 37 words ▾

Adverse Reaction Distributed by Target Corporation Minneapolis, MN 55403 Made in USA of domestic and imported materials Satisfaction guaranteed - Love it or your money back. We welcome any questions you may have at Target.com/comments or 1-800-910-6874.

🧪 Active Ingredient 5 words ▾

Active ingredient Witch hazel 50%

🧪 Inactive Ingredients 21 words ▾

Inactive ingredients 2-Bromo-2-Nitropropane-1,3-Diol, Aloe Barbadensis Leaf Juice, Citric Acid, Disodium Cocoamphodiacetate, Glycerin, Iodopropynyl Butylcarbamate, PEG-75 Lanolin, Propylene Glycol, Sodium Citrate, Water

🎯 Purpose 2 words ▾

Purpose Astringent

📄 When Using This Product 33 words ▾

When using this product do not exceed the recommended daily dosage unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator

📄 Stop Use and Ask a Doctor If 18 words ▾

Stop use and ask a doctor if bleeding occurs condition worsens or does not improve within 7 days

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.(1-800-222-1222)

📄 Other Information 8 words ▾

Other information store at room temperature 20-25ºC (68-77ºF)

📄 Package Label / Principal Display Panel 52 words ▾

Principal display panel Compare to active ingredient in Preparation H ® Medicated Wipes* Maximum Strength Hemmorrhoidal Wipes Gentle Hemorrhoidal Care with witch hazel and aloe to cool No fragrance added up & up™ FLUSHABLE 48 Count 48 MEDICATED WIPES 6 in x 5 in (15.2cm x 12.7 cm) image description image description

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Target Corporation. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 1 other package presentation of this same product, including 2 cellos (11673-0404-96). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Target Corporation is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 11673-0399-02 · TARGET 11673-0410-06 · TARGET →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.