AER Pre-moistened Witch Hazel Pad 500 mg/mL Solution, 40 applicators
by Birchwood Laboratories LLC · 40 APPLICATOR in 1 JAR (50289-3250-1) / 2.8 mL in 1 APPLICATOR
NDC 50289-3250-01
🏷️ FDA NDC (as labeled)
50289-3250-1
billing pads the package segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
50289-3250-1
Product NDC
50289-3250
11-digit billing NDC
50289325001
NCPDP billing unit
EA — each (per item)
UNII
101I4J0U34
UPC
0350289325012
Application #
M015
SPL Set ID
1cca622f-0a6b-4f35-9355-34c249ee705e
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2018-06-28
Route
RECTAL, TOPICAL
Dosage form
SOLUTION
Substance
WITCH HAZEL
GPI-14
90971040004300
GPI class
A.E.R. Witch Hazel
GCN Seq No
059607
GCN
25328
HICL code
033165
Ingredient (HICL)
Glycerin/Witch Hazel
HIC1 code
L
Therapeutic class — broad (HIC1)
Skin/Subcutaneous Tissue
HIC2 code
L4
Therapeutic class — intermediate (HIC2)
Astringents
HIC3 code
L4A
Therapeutic class — specific (HIC3)
Astringents
AHFS code
84:12.00.00
AHFS class
Astringents (84:12)
FDB label name
A.E.R PADS
FDB brand name
A.e.r
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 50289-3250-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 50289-3250-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerBirchwood Laboratories LLC
FDA applicationM015 (OTC MONOGRAPH DRUG)
Labeler code50289
First marketedJun 2018
Product typeHuman Otc Drug
Portfolio3 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name A.E.R PADS Ingredient Glycerin/Witch Hazel
🧪 What is this product?
This product is an over-the-counter witch hazel solution packaged as a pre-moistened pad for topical and rectal use. Witch hazel is commonly used as an astringent, meaning it may help tighten tissue and reduce irritation. This preparation follows an FDA monograph standard for OTC products in its category rather than undergoing individual review as a new drug application.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Witch Hazel?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Size108 mm
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII XF417D3PSL
Anhydrous citric acid is a sour, crystalline powder derived from citric acid with water removed. In medicines, it acts as a buffer to control pH, adds tartness to improve taste, and helps tablets disintegrate.
-
UNII F5UM2KM3W7
Benzalkonium chloride is a chemical compound that works as a preservative and antimicrobial agent in medications. It prevents bacterial and fungal growth in liquid formulations to keep the product safe during storage and use.
-
UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
-
UNII A2I8C7HI9T
Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
-
UNII 1Q73Q2JULR
Sodium citrate is a salt derived from citric acid. It works as a buffer to maintain the medicine's pH level and may also help improve taste or act as a preservative in the formulation.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
6 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesBenzalkonium Chloride, Citric Acid, Glycerin, Methylparaben, Purified Water, Sodium Citrate
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Major Medi-Pads 50 g/100g 00904-6829-60 | Major | 100 packets | $0.044 | — | Availability likely | — |
| Medicated Hemorrhoidal Pads 500 mg/mL 70000-0364-01 | Cardinal | 1 jar | $0.044 | — | Availability likely | — |
| QC Medicated Cooling 500 mg 83324-0311-01 | Chain | 1 jar | $0.044 | — | Availability likely | — |
| Pre-moistened Medicated Wipes, Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent, Walgreens Pre-moistened Medicated Wipes, Walgreens Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent 50 mg/100mg 00363-1740-48 | Walgreens | 48 patches | — | — | FDA listed | — |
| Preparation H Medicated Wipes 5 g 00573-0556-07 | Haleon | 10 packets | — | — | FDA listed | — |
| Preparation H Medicated Wipes 5 g 00573-0557-01 | Haleon | 48 cloths | — | — | FDA listed | — |
| Preparation H Totables Irritation Relief Wipes 5 g 00573-0558-07 | Haleon | 10 packets | — | — | FDA listed | — |
| Tucks Medicated Cooling Pads 500 mg/mL 10157-2103-01 | Blistex | 1 jar | — | — | FDA listed | — |
| up and up medicated wipes manixim strength .5 g/g 11673-0404-48 | Target | 48 applicators | — | — | FDA listed | — |
| medicated pads 50 mg/100mg 11673-0614-10 | TARGET | 100 patches | — | — | FDA listed | — |
| Signature Care Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 mg/mL 21130-0800-48 | Better | 252 ml | — | — | FDA listed | — |
| Signature Care Medicated Cooling 500 mg 21130-0928-00 | Better | 100 cloths | — | — | FDA listed | — |
| Kroger Medicated Wipes Hemorrhoidal Wipe With Witch Hazel And Aloe .5 g/g 30142-0791-71 | The | 252 g | — | — | FDA listed | — |
| hemorrhoidal pads 500 mg/1000mg 41250-0868-10 | Meijer | 100 patches | — | — | FDA listed | — |
| medicated wipes 500 mg/1000mg 41250-0988-48 | Meijer | 48 patches | — | — | FDA listed | — |
| Maximum Strength Hemorrhoidal Pads 500 mg 49035-0465-10 | Walmart, | 100 cloths | — | — | FDA listed | — |
| Equate Hemorrhoidal Medicated Wipes .5 mg/mL 49035-0793-41 | Walmart | 252 ml | — | — | FDA listed | — |
| AER Pre-moistened Witch Hazel Pad 500 mg/mLthis 50289-3250-01 | Birchwood | 40 applicators | — | — | FDA listed | — |
| AER Traveler Towelette .5 g 50289-4200-01 | Birchwood | 50 packets | — | — | FDA listed | — |
| B-SURE Traveler Towelette .5 g/g 50289-9250-01 | Birchwood | 4 g | — | — | FDA listed | — |
| Good Sense Medicated 500 mg 50804-0047-60 | Geiss, | 100 cloths | — | — | FDA listed | — |
| GOODSENSE Maximum Strength Medicated 50 g/100g 50804-0211-48 | GEISS, | 48 packets | — | — | FDA listed | — |
| Perineal Cooling Liners 500 mg/g 51316-0716-00 | CVS | 24 patches | — | — | FDA listed | — |
| TN Dickinsons Witch Hazel Hemorrhoidal Pads 1.2 g 52651-0003-01 | Dickinson | 1 jar | — | — | FDA listed | — |
| T.N. Dickinsons Witch Hazel Medicated Cooling Pads Hemorrhoidal Relief .034 g 52651-0010-01 | Dickinson | 1 jar | — | — | FDA listed | — |
| The Pharma-C Company Medicated Hemorrhoidal Pads 500 mg/mL 55239-0359-00 | Kleen | 100 patches | — | — | FDA listed | — |
| Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 55319-0402-00 | FAMILY | 48 patches | — | — | Discontinued | — |
| FAMILY Wellness MEDICATED HEMORRHOIDAL WIPES 50 g/100mL 55319-0774-01 | Family | 1 pouch | — | — | FDA listed | — |
| Rexall Medicated WipesHemorrhoidal wipe Hemorrhoidal wipes with witch hazel 129 g/258g 55910-0105-48 | Old | 258 g | — | — | FDA listed | — |
| Witch Hazel 50 g/1001 56194-0550-01 | Giant | 48 cloths | — | — | FDA listed | — |
| Geri Care Medicated Pads 50 mg/mL 57896-0115-01 | Geri-Care | 100 patches | — | — | FDA listed | — |
| Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 g/g 59779-0607-10 | CVS | 48 applicators | — | — | FDA listed | — |
| CVS Health Medicated 500 mg 59779-0747-01 | CVS | 1 jar | — | — | FDA listed | — |
| Meicated Wipe 50 g/100g 64709-0120-01 | Diamond | 195.09 g | — | — | FDA listed | — |
| Dr Talbots Cooling Perineal Pad .5 g/g 70797-0104-01 | Talbot's | 120 g | — | — | FDA listed | — |
| Dr Butlers Hemorrhoid 50 g/100g 70942-0100-48 | Beyond | 3 g | — | — | FDA listed | — |
| Hemorrhoidal Hygiene pads 50 g/100mL 71399-0110-01 | Akron | 175 ml | — | — | FDA listed | — |
| Flushable Hemorrhoidal Medicated Wipes Maximum Strength .5 g 72288-0923-01 | Amazon.com | 48 cloths | — | — | FDA listed | — |
| frida mom Perineal Cooling Pad Liners .5 g 72705-0100-01 | Fridababy, | 24 cloths | — | — | FDA listed | — |
| Perineal Cooling Pad Liners 50 g/100g 72705-0420-01 | Fridababy, | 100 g | — | — | FDA listed | — |
| Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 72932-0009-00 | Wuhan | 48 patches | — | — | FDA listed | — |
| Medicated Multipurpose Wipes 50 mg/100mg 78691-0050-15 | QUEST | 15 patches | — | — | FDA listed | — |
| Soothing Hemorrhoidal Wipes 50 Witch Hazel 500 mg/mL 82637-0059-01 | The | 30 patches | — | — | FDA listed | — |
| Pura 50 mg 84217-0050-48 | Mypura.com | 48 patches | — | — | FDA listed | — |
| Norms Medicated Wipes .5 g/g 85996-0001-01 | Totally | 1 g | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2018
On the market since
Jun 2018
📍
2026
Currently FDA-listed
8 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for AER Pre-moistened Witch Hazel Pad (this brand).
Top reported reactions
Reporter sex
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 50289-3250-01 You're viewing this | 40 APPLICATOR in 1 JAR (50289-3250-1) / 2.8 mL in 1 APPLICATOR | 2018-06-28 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 50289-3250-1, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 50289-3250-01, written without dashes as 50289325001. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 50289-3250-01, the first segment (50289) is the labeler code FDA assigned to Birchwood Laboratories LLC; the middle segment (3250) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (01) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Birchwood Laboratories LLC. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Birchwood Laboratories LLC is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses Temporary relief of anal itching and burning Temporarily protects irritated tissues
⏱️ Dosage and Administration ▾
Directions Gently apply to affected areas by patting and then discard
⚠️ Warnings ▾
Warnings For external rectal use only Stop use and ask doctor if rectal bleeding or continued irritation occurs
🧪 Active Ingredient ▾
Active Ingredient Witch Hazel 50%
🧪 Inactive Ingredients ▾
Inactive Ingredients Benzalkonium Chloride, Citric Acid, Glycerin, Methylparaben, Purified Water, Sodium Citrate
🎯 Purpose ▾
Purpose Astringent
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.