Perineal Cooling Liners WITCH HAZEL 500 mg/g Swab, 24 patches
by CVS Pharmacy · 1 BAG in 1 BOX (51316-716-00) / 24 PATCH in 1 BAG / 3.7 g in 1 PATCH
NDC 51316-0716-00
🏷️ FDA NDC (as labeled)
51316-716-00
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
51316-716-00
Product NDC
51316-716
11-digit billing NDC
51316071600
RxCUI
844379
UNII
101I4J0U34
Application #
M016
SPL Set ID
88f44650-8fb7-4eb2-901d-30eb8415dc2b
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2022-10-30
Route
TOPICAL
Dosage form
SWAB
Substance
WITCH HAZEL
Why two NDCs?
The FDA registers this code as 51316-716-00 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 51316-0716-00. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏭 Manufacturer & labeler
LabelerCVS Pharmacy
FDA applicationM016 (OTC MONOGRAPH DRUG)
Labeler code51316
First marketedOct 2022
Product typeHuman Otc Drug
Portfolio550 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
🧪 What is this product?
This is an over-the-counter topical swab product containing witch hazel, an astringent substance typically used as a perineal cooling and soothing agent. Witch hazel is commonly found in products designed to provide comfort and mild astringent action on skin. These swabs are marketed as an OTC monograph drug, meaning they are sold under FDA guidelines for this category of topical astringent products rather than as individually reviewed medications.
Patient education
Supplement & herbal interactions
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about WITCH HAZEL?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured
IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per each | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Major Medi-Pads 50 g/100g 00904-6829-60 | Major | 100 packets | $0.044 | — | Availability likely | — |
| Medicated Hemorrhoidal Pads 500 mg/mL 70000-0364-01 | Cardinal | 1 jar | $0.044 | — | Availability likely | — |
| QC Medicated Cooling 500 mg 83324-0311-01 | Chain | 1 jar | $0.044 | — | Availability likely | — |
| Pre-moistened Medicated Wipes, Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent, Walgreens Pre-moistened Medicated Wipes, Walgreens Pre-moistened Medicated Wipes Witch Hazel 50%/Hemorrhoidal Astringent 50 mg/100mg 00363-1740-48 | Walgreens | 48 patches | — | — | FDA listed | — |
| Preparation H Medicated Wipes 5 g 00573-0556-07 | Haleon | 10 packets | — | — | FDA listed | — |
| Preparation H Medicated Wipes 5 g 00573-0557-01 | Haleon | 48 cloths | — | — | FDA listed | — |
| Preparation H Totables Irritation Relief Wipes 5 g 00573-0558-07 | Haleon | 10 packets | — | — | FDA listed | — |
| Tucks Medicated Cooling Pads 500 mg/mL 10157-2103-01 | Blistex | 1 jar | — | — | FDA listed | — |
| up and up medicated wipes manixim strength .5 g/g 11673-0404-48 | Target | 48 applicators | — | — | FDA listed | — |
| medicated pads 50 mg/100mg 11673-0614-10 | TARGET | 100 patches | — | — | FDA listed | — |
| Signature Care Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 mg/mL 21130-0800-48 | Better | 252 ml | — | — | FDA listed | — |
| Signature Care Medicated Cooling 500 mg 21130-0928-00 | Better | 100 cloths | — | — | FDA listed | — |
| Kroger Medicated Wipes Hemorrhoidal Wipe With Witch Hazel And Aloe .5 g/g 30142-0791-71 | The | 252 g | — | — | FDA listed | — |
| hemorrhoidal pads 500 mg/1000mg 41250-0868-10 | Meijer | 100 patches | — | — | FDA listed | — |
| medicated wipes 500 mg/1000mg 41250-0988-48 | Meijer | 48 patches | — | — | FDA listed | — |
| Maximum Strength Hemorrhoidal Pads 500 mg 49035-0465-10 | Walmart, | 100 cloths | — | — | FDA listed | — |
| Equate Hemorrhoidal Medicated Wipes .5 mg/mL 49035-0793-41 | Walmart | 252 ml | — | — | FDA listed | — |
| AER Pre-moistened Witch Hazel Pad 500 mg/mL 50289-3250-01 | Birchwood | 40 applicators | — | — | FDA listed | — |
| AER Traveler Towelette .5 g 50289-4200-01 | Birchwood | 50 packets | — | — | FDA listed | — |
| B-SURE Traveler Towelette .5 g/g 50289-9250-01 | Birchwood | 4 g | — | — | FDA listed | — |
| Good Sense Medicated 500 mg 50804-0047-60 | Geiss, | 100 cloths | — | — | FDA listed | — |
| GOODSENSE Maximum Strength Medicated 50 g/100g 50804-0211-48 | GEISS, | 48 packets | — | — | FDA listed | — |
| Perineal Cooling Liners 500 mg/gthis 51316-0716-00 | CVS | 24 patches | — | — | FDA listed | — |
| TN Dickinsons Witch Hazel Hemorrhoidal Pads 1.2 g 52651-0003-01 | Dickinson | 1 jar | — | — | FDA listed | — |
| T.N. Dickinsons Witch Hazel Medicated Cooling Pads Hemorrhoidal Relief .034 g 52651-0010-01 | Dickinson | 1 jar | — | — | FDA listed | — |
| The Pharma-C Company Medicated Hemorrhoidal Pads 500 mg/mL 55239-0359-00 | Kleen | 100 patches | — | — | FDA listed | — |
| Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 55319-0402-00 | FAMILY | 48 patches | — | — | Discontinued | — |
| FAMILY Wellness MEDICATED HEMORRHOIDAL WIPES 50 g/100mL 55319-0774-01 | Family | 1 pouch | — | — | FDA listed | — |
| Rexall Medicated WipesHemorrhoidal wipe Hemorrhoidal wipes with witch hazel 129 g/258g 55910-0105-48 | Old | 258 g | — | — | FDA listed | — |
| Witch Hazel 50 g/1001 56194-0550-01 | Giant | 48 cloths | — | — | FDA listed | — |
| Geri Care Medicated Pads 50 mg/mL 57896-0115-01 | Geri-Care | 100 patches | — | — | FDA listed | — |
| Medicated Wipes Hemorrhoidal Wipes with Witch Hazel .5 g/g 59779-0607-10 | CVS | 48 applicators | — | — | FDA listed | — |
| CVS Health Medicated 500 mg 59779-0747-01 | CVS | 1 jar | — | — | FDA listed | — |
| Meicated Wipe 50 g/100g 64709-0120-01 | Diamond | 195.09 g | — | — | FDA listed | — |
| Dr Talbots Cooling Perineal Pad .5 g/g 70797-0104-01 | Talbot's | 120 g | — | — | FDA listed | — |
| Dr Butlers Hemorrhoid 50 g/100g 70942-0100-48 | Beyond | 3 g | — | — | FDA listed | — |
| Hemorrhoidal Hygiene pads 50 g/100mL 71399-0110-01 | Akron | 175 ml | — | — | FDA listed | — |
| Flushable Hemorrhoidal Medicated Wipes Maximum Strength .5 g 72288-0923-01 | Amazon.com | 48 cloths | — | — | FDA listed | — |
| frida mom Perineal Cooling Pad Liners .5 g 72705-0100-01 | Fridababy, | 24 cloths | — | — | FDA listed | — |
| Perineal Cooling Pad Liners 50 g/100g 72705-0420-01 | Fridababy, | 100 g | — | — | FDA listed | — |
| Medicated Wipes Hemorroidal Wipes With Witch Hazel 500 mg/mL 72932-0009-00 | Wuhan | 48 patches | — | — | FDA listed | — |
| Medicated Multipurpose Wipes 50 mg/100mg 78691-0050-15 | QUEST | 15 patches | — | — | FDA listed | — |
| Soothing Hemorrhoidal Wipes 50 Witch Hazel 500 mg/mL 82637-0059-01 | The | 30 patches | — | — | FDA listed | — |
| Pura 50 mg 84217-0050-48 | Mypura.com | 48 patches | — | — | FDA listed | — |
| Norms Medicated Wipes .5 g/g 85996-0001-01 | Totally | 1 g | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2022
On the market since
Oct 2022
📍
2026
Currently FDA-listed
4 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Perineal Cooling Liners (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 35%
Female · 65%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 51316-0716-00 You're viewing this | 1 BAG in 1 BOX (51316-716-00) / 24 PATCH in 1 BAG / 3.7 g in 1 PATCH | 2022-10-30 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available. |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 51316-716-00, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 51316-0716-00, written without dashes as 51316071600. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 51316-0716-00, the first segment (51316) is the labeler code FDA assigned to CVS Pharmacy; the middle segment (0716) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (00) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by CVS Pharmacy. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
CVS Pharmacy is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses Helps relieve pain and swelling from hemorrhoids and childbirth. Temporary relief from: Irritation Burning Discomfort.
⏱️ Dosage and Administration ▾
Directions remove one pad liner from pouch and place on top of maxi pad. close lid after use to retain moisture. replace pad liner with each maxi pad change.
⚠️ Warnings ▾
Warnings For external use only. When using this product avoid contact with eyes. if contact occurs, rinse thoroughly with water. do not exceed the recommended daily dosage unless directed by a doctor. do not put this product into the rectum by using fingers or any mechanical device or applicator. Stop use and ask a doctor if rectal bleeding occurs. condition worsens or does not improve within 7 days.
Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
🧪 Active Ingredient ▾
Active ingredient Witch hazel 50% Purpose Astringent
🧪 Inactive Ingredients ▾
Inactive ingredients water, alcohol, sodium benzoate, phenoxyethanol, sodium lauroamphoacetate, benzalkonium chloride, glycerin, benzoic acid, citric acid, Mentha Piperita (Peppermint) Oil, menthyl lactate, sodium citrate, Chamomilla Recutita (Matricaria) Extract, tocopherol
🎯 Purpose ▾
Purpose Astringent
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.