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Witch Hazel 860 mg/mL Liquid, 473 mL — NDC 37808-0822-43 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Witch Hazel 860 mg/mL Liquid, 473 mL — NDC 37808-822-43 (Billing 37808-0822-43)

by H E B · 473 mL in 1 BOTTLE, PLASTIC

This is a package of 473 mL of Witch Hazel 860 mg/mL Liquid from H E B, marketed since Jun 2015 and currently FDA-listed. It is the main listing for this product, which comes in 3 package sizes.

NDC 37808-0822-43
🏷️ FDA NDC (as labeled) 37808-822-43 billing pads the product segment with a zero
This package
Contains473 mL Pack sizes3 compare ↓
Main listing for product 37808-822 · Also comes in: 236 ml 37808-822-99 946 ml 37808-822-45
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 8, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 37808-822-43 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
37808 labeler · 822 product · 43 package
Package marketed since
Jun 18, 2015
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Barcode (UPC-A, from the NDC)
3 3780882243 6
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 37808-822-43
Product NDC 37808-822
11-digit billing NDC 37808082243
RxCUI 200295
UNII 101I4J0U34
Application # M015
SPL Set ID 09b814f4-86b5-4810-bf52-cc88396451c2
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2015-06-18
Route TOPICAL
Dosage form LIQUID
Substance WITCH HAZEL
Quick answers
  • RxCUI (RxNorm): 200295
Why two NDCs? The FDA registers this code as 37808-822-43 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 37808-0822-43. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

Clinical

🧪 What is this product?

This is a topical liquid product containing witch hazel, an herbal extract commonly applied to the skin. Witch hazel is traditionally used in over-the-counter products for cleansing and as an astringent, meaning it is thought to help tighten or tone the skin. This product is marketed as an OTC monograph drug, which means it follows established FDA guidelines for this category rather than undergoing individual new drug review. The liquid form allows for easy application directly to the skin.

Supplement & herbal interactions

🌿 Drug–supplement interaction checker →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 236 ml 946 ml
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
37808-0822-43 You're viewing this Main listing 473 mL in 1 BOTTLE, PLASTIC 2015-06-18 — Active
37808-0822-45 37808-822-45 946 mL in 1 BOTTLE, PLASTIC 2015-06-18 — Discontinued by firm
37808-0822-99 37808-822-99 236 mL in 1 BOTTLE, PUMP 2015-06-18 — Discontinued by firm

You're viewing one of 3 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This package contains 473 mL — 473 ml in 1 bottle, plastic.
How does this package differ from NDC 37808-0822-99?
Both are Witch Hazel 860 mg/mL Liquid — the drug itself is identical. This page's package is the 473 mL one, while NDC 37808-0822-99 is the 236 ml package.
What NDC number is used to bill for this package of Witch Hazel 860 mg/mL Liquid?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Health Mart Witch Hazel 855 mg/mL 62011-0268-01 Strategic 473 ml $0.006 — FDA listed —
Sunmark Witch Hazel 855 mg/mL 49348-0181-38 Strategic 473 ml $0.007 — Availability likely —
GNP Witch Hazel 855 mg/mL 46122-0335-43 Amerisource 473 ml $0.008 — Availability likely —
Witch Hazel 842 mg/mL 70000-0615-01 Cardinal 473 ml $0.008 — Availability likely —
Witch Hazel 842 mg/mL 70677-1252-01 Strategic 473 ml $0.008 — Availability likely —
Witch Hazel 860 mg/mL 00363-0803-43 Walgreen 473 ml — — FDA listed —
Witch Hazel 86 g/100mL 10565-0040-16 Hydrox 473 ml — — FDA listed —
Witch Hazel 86 g/100mL 10733-0801-08 Medical 236 ml — — FDA listed —
Witch Hazel 860 mg/mL 11344-0822-43 Nice-Pak 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 21130-0822-43 Better 473 ml — — FDA listed —
Kroger Witch Hazel .86 g/mL 30142-0418-16 Kroger 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 30142-0822-43 The 473 ml — — FDA listed —
Witch Hazel 860 mg/mLthis 37808-0822-43 H 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 41163-0822-43 United 473 ml — — FDA listed —
Witch Hazel 86 kg/100L 41250-0822-43 Meijer, 473 l — — FDA listed —
Witch Hazel 860 mg/mL 41520-0822-43 ADUSA 473 ml — — FDA listed —
Witch Hazel ReadyInCase 86 g/100mL 49580-0390-06 P 473 ml — — FDA listed —
TN Dickinsons Witch Hazel Astringent 86 g/100mL 52651-0001-04 Dickinson 3785 ml — — FDA listed —
Witch Hazel 860 mg/mL 55301-0822-43 Your 473 l — — FDA listed —
Witch Hazel 860 mg/mL 56062-0822-43 Publix 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 59779-0045-43 CVS 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 63941-0822-43 Valu 473 ml — — FDA listed —
Witch Hazel 86 g/100mL 70082-0008-16 DealMed 473 ml — — FDA listed —
Witch Hazel 86 g/100mL 71990-0001-01 Arcadia 473 ml — — FDA listed —
Witch Hazel 860 mg/mL 72288-0922-26 Amazon.com 118 ml — — Discontinued —
Witch Hazel 860 mg/mL 76162-0822-43 Topco 473 ml — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2015
On the market since
Jun 2015
📍
2026
Currently FDA-listed
11 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 3K9958V90M
    A liquid solvent derived from fermentation or chemical synthesis. In medicines, alcohol dissolves active ingredients, helps preserve the product, and improves how the body absorbs certain drugs.

1 inactive ingredient listed in the exact product block matched to this NDC.

The official label also statesNone

Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerH E B
FDA applicationM015 (OTC MONOGRAPH DRUG)
Labeler code37808
First marketedJun 2015
Product typeHuman Otc Drug
Portfolio264 products on file

More NDCs from H E B labeler code 37808

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 🤒 Adverse Reactions 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 When Using This Product 📄 Stop Use and Ask a Doctor If 📄 Keep Out of Reach of Children 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 15 words ▾

Use for relief of minor skin irritations due to: insect bites minor cuts minor scrapes

⏱️ Dosage and Administration 6 words ▾

Directions apply as often as needed

⚠️ Warnings 5 words ▾

Warnings For external use only

🤒 Adverse Reactions 44 words ▾

adverse reaction MADE WITH PRIDE & CARE FOR H-E-B ® SAN ANTONIO, TX 78204 100% GUARANTEE promise If you aren't completely pleased with this product, we'll be happy to replace it or refund your money. You have our word on it. Pat. D675, 101

🧪 Active Ingredient 10 words ▾

Active ingredient Witch hazel 100% (containing alcohol 14% by volume)

🧪 Inactive Ingredients 3 words ▾

Inactive ingredient None

🎯 Purpose 2 words ▾

Purpose Astringent

📄 When Using This Product 16 words ▾

When using this product avoid contact with the eyes. If contact occurs, rinse thoroughly with water.

📄 Stop Use and Ask a Doctor If 17 words ▾

Stop use and ask a doctor if condition worsens or symptoms lasts for more than 7 days

📄 Keep Out of Reach of Children 19 words ▾

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

📄 Package Label / Principal Display Panel 39 words ▾

principal display panel H-E-B ® Witch Hazel U.S.P. Astringent Cleans & Refreshes For Relief of Minor Skin Irritations due to: Insects Bites - Minor Cuts - Minor Scrapes 16 FL OZ (1 PT) 473 mL image description image description

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by H E B. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 236 ml (37808-0822-99), 946 ml (37808-0822-45). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
H E B is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 37808-0821-16 · H 37808-0825-29 · H →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.