Senna UD Sennosides 26.4 mg/15mL Syrup
by Patrin Pharma, Inc. · 5 TRAY in 1 CASE (39328-220-50) / 10 CUP, UNIT-DOSE in 1 TRAY / 15 mL in 1 CUP, UNIT-DOSE (39328-220-15)
NDC 39328-0220-50
🏷️ FDA NDC (as labeled)
39328-220-50
billing pads the product segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
39328-220-50
Product NDC
39328-220
11-digit billing NDC
39328022050
NCPDP billing unit
ML — per mL (volume)
RxCUI
702311
UNII
3FYP5M0IJX
UPC
0339328120054, 0339328220150
Application #
M007
SPL Set ID
a9f1ef8d-8700-481f-a709-972bb9d27153
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2023-10-01
Route
ORAL
Dosage form
SYRUP
Substance
SENNOSIDES
GPI-14
46200060201220
GCN Seq No
002922
GCN
08660
HICL code
001289
Ingredient (HICL)
Sennosides
HIC1 code
D
Therapeutic class — broad (HIC1)
Biliary System/Gastro-Intestinal System
HIC2 code
D6
Therapeutic class — intermediate (HIC2)
Drugs Acting Principally On The Colon
HIC3 code
D6S
Therapeutic class — specific (HIC3)
Laxatives And Cathartics
AHFS code
56:12.00.00
AHFS class
Cathartics And Laxatives
FDB label name
SENNA 26.4 MG/15 ML SYRUP CUP
FDB brand name
Senna
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 39328-220-50 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 39328-0220-50. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Contact laxatives class.
Drug family (ATC)
Contact laxatives
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerPatrin Pharma, Inc.
FDA applicationM007 (OTC MONOGRAPH DRUG)
Labeler code39328
First marketedOct 2023
Product typeHuman Otc Drug
Portfolio18 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name SENNA 26.4 MG/15 ML SYRUP CUP Ingredient Sennosides
📖 What it is MedlinePlus · NLM
Senna is used on a short-term basis to treat constipation. It also is used to empty the bowels before surgery and certain medical procedures. Senna is in a class of medications called stimulant laxatives. It works by increasing activity of the intestines to cause a bowel movement.
Read the full MedlinePlus article ↗📗 Our plain-language guide HelloPharmacist
- Senna typically produces a bowel movement within 6 to 12 hours. That's why most people take it at bedtime — so it can do its job overnight and you get results in the morning. If no...
- How long does it take for senna to work?
- Senna is designed for short-term, occasional use. You should not use it for more than 1 week unless your doctor specifically tells you it's okay. Using laxatives too often or for t...
- Laxatives like senna can affect how your body absorbs other medications. To be safe, take senna at least 2 hours before or after any other drugs you use. It's always a good idea to...
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Sennosides (OTC drug) — tap one for details:
3
Nutrient depletion considerations
Sennosides (OTC drug) may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Sennosides?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
💊 What it looks like
Color
Brown
FlavorChocolate
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
-
UNII A2I8C7HI9T
Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
-
UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
-
UNII Z8IX2SC1OH
Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
-
UNII C151H8M554
A natural sugar derived from sugar cane or sugar beets. It's used as a sweetener, filler, and binder to improve taste, add bulk, and help hold tablet or capsule ingredients together.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
5 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statesChocolate flavor, methylparaben, propylene glycol, propylparaben, purified water and sucrose
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per mL | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Senna Liquid 8.8 mg/5mL 00536-1266-59 | RUGBY | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 39328-0020-08 | Patrin | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mL 54859-0808-08 | Llorens | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mL 57237-0301-24 | Rising | 237 ml | $0.038 | — | Availability likely | — |
| Senna Syrup 8.8 mg/5mL 58657-0518-08 | Method | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 82568-0024-08 | AARNA | 237 ml | $0.038 | — | Availability likely | — |
| Senna 8.8 mg/5mL 00121-4967-40 | PAI | 10 cups | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 00536-1483-59 | Rugby | 237 ml | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 00904-7528-94 | Major | 10 cups | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 17856-1127-01 | ATLANTIC | 120 syringes | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 17856-8127-02 | Atlantic | 50 cups | — | — | FDA listed | — |
| Senna UD 8.8 mg/5mL 39328-0120-50 | Patrin | 10 cups | — | — | FDA listed | — |
| Senna UD 26.4 mg/15mLthis 39328-0220-50 | Patrin | 10 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 48433-0219-40 | Safecor | 40 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 50268-0731-24 | AVPAK | 24 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 57237-0310-54 | Rising | 40 cups | — | — | FDA listed | — |
| GeriCare Senna Syrup 8.8 mg/5mL 57896-0472-08 | Geri-Care | 237 ml | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 60687-0851-77 | American | 10 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 63629-9268-01 | Bryant | 237 ml | — | — | FDA listed | — |
| SENNA Syrup 8.8 mg/5mL 66424-0562-08 | SDA | 236 ml | — | — | FDA listed | — |
| Senna 417.12 mg/237mL 68094-0049-62 | Precision | 10 cups | — | — | FDA listed | — |
| Senna 8.8 mg/5mL 69618-0069-58 | Reliable | 237 ml | — | — | FDA listed | — |
| OneLAX SENNA 417.12 mg/237mL 71399-0027-08 | Akron | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 72090-0022-01 | Pioneer | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 72162-1672-02 | Bryant | 237 ml | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 73564-0812-08 | Aldama | 1 bottle | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 81033-0120-50 | Kesin | 50 cups | — | — | FDA listed | — |
| Senna Syrup 8.8 mg/5mL 84415-0021-01 | Everpharm | 100 cups | — | — | FDA listed | — |
| Senna Liquid 8.8 mg/5mL 84447-0120-01 | Belleview | 200000 ml | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2023
On the market since
Oct 2023
📍
2026
Currently FDA-listed
3 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Senna UD (this brand).
Top reported reactions
Age at onset
Reporter sex
Male · 48%
Female · 52%
Unknown · 0%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 39328-0220-50 You're viewing this | 5 TRAY in 1 CASE (39328-220-50) / 10 CUP, UNIT-DOSE in 1 TRAY / 15 mL in 1 CUP, UNIT-DOSE (39328-220-15) | 2023-10-01 | Active |
🧭 About this NDC listing & data coverage
Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | ✓ Available |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.
Questions about this listing
Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The FDA registers it as 39328-220-50, which is what is printed on the packaging and shown on DailyMed. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero: 39328-0220-50, written without dashes as 39328022050. The Identity section at the top of this page lists every form of this code.
What do the three segments of this NDC mean?
In 39328-0220-50, the first segment (39328) is the labeler code FDA assigned to Patrin Pharma, Inc.; the middle segment (0220) identifies this specific product — its ingredient, strength, and dosage form; and the last segment (50) identifies this exact package size and type. Together they name one specific package of one specific product.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Patrin Pharma, Inc.. Listing status can change — the directory data on this page refreshes weekly.
Who lists this product with the FDA?
Patrin Pharma, Inc. is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 How Supplied / Storage and Handling
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses Relieves occasional constipation (irregularity) Generally causes bowel movement in 6 to 12 hours
⏱️ Dosage and Administration ▾
Directions Shake well before using. Do not exceed maximum dose. Take at bedtime or as directed by a doctor.
AGE USUAL DOSE MAXIMUM DOSAGE Adults and children 12 years and older 2-3 teaspoons (10 to 15 mL) once a day 3 teaspoons (15 mL) twice a day 6 to 12 years 1 to 1 1/2 teaspoons (5 to 7.5 mL) once a day 1 1/2 teaspoons (7.5 mL) twice a day 2 to 6 years 1/2 to 3/4 teaspoons (2.5 to 3.75 mL) once a day 3/4 teaspoon (3.75 mL) once a day under 2 years of age Consult a doctor
⚠️ Warnings ▾
Warnings Do not use laxative products for longer than one week unless directed by a doctor. Ask a doctor before use if you have stomach pain, nausea or vomiting notice a change in bowel habits that last over two weeks are pregnant or breast feeding Stop use and ask a doctor if you have rectal bleeding or failure to have a bowel movement after use. Keep out of reach of children.
In case of accidental overdose, get medical help or contact a Poison Control Center immediately.
📦 How Supplied / Storage and Handling ▾
How Supplied A chocolate flavored syrup supplied in the following oral dosage cup: NDC 39328-120-05: NDC 39328-120-50: 5 mL unit dose cup Case contains 50 unit dose cups of 5 mL NDC 39328-220-15: NDC 39328-220-50: 15 mL unit dose cup Case contains 50 unit dose cups of 15 mL
📦 Storage and Handling ▾
Other Information Store at controlled room temperature 20-25°C (68-77°F). Excursions permitted 15-30°C (59-86°F). Tamper-Evident: Do not use if foil seal over cup is torn or broken.
🧪 Active Ingredient ▾
Active ingredient (in each 5 mL = 1 teaspoonful) Sennosides 8.8 mg
🧪 Inactive Ingredients ▾
Inactive Ingredients Chocolate flavor, methylparaben, propylene glycol, propylparaben, purified water and sucrose
🎯 Purpose ▾
Purpose Laxative
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.