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doxycycline 100 mg Capsule, 500-count — NDC 65841-0823-05 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

doxycycline 100 mg Capsule, 500-count — NDC 65841-823-05 (Billing 65841-0823-05)

by Zydus Lifesciences Limited · 500 CAPSULE in 1 BOTTLE

This is a package of 500 capsules of doxycycline 100 mg Capsule from Zydus Lifesciences Limited, marketed since Mar 2016 and currently FDA-listed.

NDC 65841-0823-05
🏷️ FDA NDC (as labeled) 65841-823-05 billing pads the product segment with a zero
This package
Contains500-count Pack sizes8 compare ↓
Also priced by: Part D plans $0.2701/unit — full pricing hub ↓
Product page 65841-0823-01 Also comes in: 30 capsules 65841-823-06 50 capsules 65841-823-18 90 capsules 65841-823-16 100 capsules 65841-823-01 100 capsules 65841-823-77 250 capsules 65841-823-21 1000 capsules 65841-823-10
Rx only Generic On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 65841-823-05 alone.

Record
FDA NDC Directory package listing · Human prescription drug
Code segments
65841 labeler · 823 product · 05 package
Package marketed since
Mar 14, 2016
Sample package
No — commercial package
Listing certified through
Dec 31, 2026
Barcode (UPC-A, from the NDC)
3 6584182305 9
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 65841-823-05
Product NDC 65841-823
11-digit billing NDC 65841082305
RxCUI 700408, 1649401, 1649990
UNII N12000U13O
Application # ANDA205115
SPL Set ID aa01035d-8b4a-4fdc-bfdf-2b39df0d8fc9
Established class (EPC) Tetracycline-class Drug
Chemical class Tetracyclines
DEA schedule Non-controlled
Marketing category ANDA
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2016-03-14
Route ORAL
Dosage form CAPSULE
Substance DOXYCYCLINE
TE code (Orange Book) AB · RLD · RS
Quick answers
  • RxCUI (RxNorm): 700408
Why two NDCs? The FDA registers this code as 65841-823-05 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 65841-0823-05. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Tetracycline-class Drug class.

Pharmacologic class Tetracycline-class Drug
Drug family (ATC) Antiinfectives and antiseptics for local oral treatment, Tetracyclines
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

📗 Our plain-language guide HelloPharmacist
  • It is an antibiotic for bacterial infections such as rickettsial infections, sexually transmitted infections, respiratory tract infections and eye infections. Some products are als...
  • Take it exactly as your prescriber and label say. Swallow capsules with a full glass of water and avoid taking them right before lying down. For one capsule product, take it at lea...
  • Diarrhea, nausea, vomiting, stomach upset and loss of appetite are the most common. You may also sunburn much more easily, so cover up and avoid tanning beds. Call me or your docto...
  • Call right away for severe or watery diarrhea, a blistering or peeling rash, headache with vision changes, trouble swallowing, or signs of an allergic reaction. Diarrhea can show u...
📖 Read our full Doxycycline guide →
7
Nutrient depletion considerations

Doxycycline may be associated with lower levels of 7 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Doxycycline nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · Q2 2026 $0.2701 $135.05 / 500 capsules
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
65841-0823-01 65841-823-01 Main listing 100 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-05 You're viewing this 500 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-06 65841-823-06 30 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-10 65841-823-10 1000 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-16 65841-823-16 90 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-18 65841-823-18 50 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-21 65841-823-21 250 CAPSULE in 1 BOTTLE 2016-03-14 — Active
65841-0823-77 65841-823-77 10 BLISTER PACK in 1 CARTON / 10 CAPSULE in 1 BLISTER PACK 2016-03-14 — Active

Pack size FAQ

What quantity is in this package?
This is a 500-count package — 500 capsule in 1 bottle.
How does this package differ from NDC 65841-0823-06?
Both are doxycycline 100 mg Capsule — the drug itself is identical. This page's package is the 500-count one, while NDC 65841-0823-06 is the 30 capsules package.
What NDC number is used to bill for this package of doxycycline 100 mg Capsule?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
doxycycline 100 mg 50268-0281-15 AvPAK 50 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 60687-0716-21 American 30 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 60687-0943-21 American 30 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 64380-0180-01 Strides 50 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 64380-0922-01 Strides 50 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 68180-0652-08 Lupin 50 capsules $0.227 AB Availability likely —
Doxycycline 100 mg 43386-0792-02 Lupin 250 capsules — — FDA listed —
Doxycycline 100 mg 46708-0250-30 Alembic 30 capsules — AB FDA listed —
doxycycline 100 mg 50090-4833-00 A-S 20 capsules — AB FDA listed —
Doxycycline 100 mg 50090-6783-00 A-S 20 capsules — AB FDA listed —
Doxycycline 100 mg 51655-0711-20 Northwind 20 capsules — AB FDA listed —
Doxycycline 100 mg 61919-0276-20 DIRECT 20 capsules — — FDA listed —
Doxycycline Monohydrate 100 mg 61919-0624-14 DIRECT 14 capsules — AB FDA listed —
Doxycycline Monohydrate 100 mg 62135-0262-20 Chartwell 20 capsules — AB FDA listed —
Doxycycline 100 mg 62332-0250-30 Alembic 30 capsules — AB FDA listed —
Doxycycline 100 mg 63187-0672-02 Proficient 2 capsules — AB FDA listed —
doxycycline 100 mg 63187-0712-14 Proficient 14 capsules — AB FDA listed —
Doxycycline 100 mg 63304-0616-01 Sun 100 capsules — AB FDA listed —
doxycycline 100 mgthis 65841-0823-05 Zydus 500 capsules — AB FDA listed —
Doxycycline 100 mg 68071-2152-02 NuCare 20 capsules — AB FDA listed —
Doxycycline 100 mg 68071-3752-02 NuCare 20 capsules — AB FDA listed —
doxycycline 100 mg 68382-0707-01 Zydus 100 capsules — AB FDA listed —
Doxycycline 100 mg 70518-0213-00 REMEDYREPACK 30 capsules — AB FDA listed —
Doxycycline 100 mg 71335-1988-00 Bryant 2 capsules — AB FDA listed —
Doxycycline 100 mg 71335-2417-00 Bryant 2 capsules — AB FDA listed —
Doxycycline 100 mg 71335-3064-00 Bryant 2 capsules — AB FDA listed —
Doxycycline Monohydrate 100 mg 72189-0358-20 Direct_Rx 20 capsules — AB FDA listed —
doxycycline 100 mg 72789-0491-14 PD-Rx 14 capsules — AB FDA listed —
doxycycline 100 mg 72789-0496-02 PD-Rx 2 capsules — AB FDA listed —
Doxycycline 100 mg 82804-0050-02 Proficient 2 capsules — AB FDA listed —
Doxycycline 100 mg 82804-0171-06 Proficient 6 capsules — AB FDA listed —
doxycycline 100 mg 67046-1260-03 Coupler 30 capsules — AB FDA listed —
doxycycline 100 mg 48433-0159-03 Safecor 30 capsules — AB FDA listed —
Doxycycline 100 mg 70518-4762-00 REMEDYREPACK 14 capsules — AB FDA listed —
About this product: this is a generic version of the medicine. FDA equivalence ratings are shown when available, and other versions are listed above, least expensive first.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
2016
On the market since
Mar 2016
📍
2026
Currently FDA-listed
10 years listed
🔓
·
Generic on the market
this product is a generic
✅This is a generic drug

This product is an FDA-approved generic. Other versions of the same drug are listed under Therapeutic equivalents, least expensive first.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color Yellow / White / Orange
ShapeCapsule
Imprint707
Size19 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

🧪 Avoiding an ingredient? See Doxycycline inactive ingredients by manufacturer: every current product's list side by side, so you can ask your pharmacy for the version that does not list it.

💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.

  • UNII 5138Q19F1X
    Ammonia is a colorless gas made from nitrogen and hydrogen. It's used in medicines as a pH buffer to maintain the correct acidity level and help keep the product stable.
  • UNII OP1R32D61U
    Microcrystalline cellulose is a purified form of cellulose, a natural fiber from plant sources. It acts as a binder and filler in tablets and capsules, helping hold ingredients together and give the medicine its shape and size.
  • UNII 35SW5USQ3G
    A synthetic yellow dye used to color medicines. It helps make tablets, capsules, and liquids visually distinct so patients can easily identify their medication.
  • UNII H3R47K3TBD
    FD&C Blue No. 1 is a synthetic blue dye approved for use in foods and medicines. It serves as a colorant to give the medication its distinctive appearance and help with product identification.
  • UNII PN2ZH5LOQY
    A synthetic red dye approved by the FDA for use in foods, medicines, and cosmetics. It serves as a colorant to make tablets, capsules, and liquids visually distinctive for product identification.
  • UNII H77VEI93A8
    A synthetic yellow dye used to color medications. It helps identify the drug and make it visually distinctive, with no effect on how the medicine works.
  • UNII 1K09F3G675
    Ferric oxide red is an inorganic iron compound used as a colorant in medicines. It gives tablets, capsules, or other dosage forms a red or reddish tint for identification and appearance.
  • UNII EX438O2MRT
    Ferric oxide yellow is a naturally occurring iron compound used as a colorant in medications. It gives tablets, capsules, and other forms a yellow or golden hue for identification and appearance.
  • UNII XM0M87F357
    A dark iron oxide compound that gives medicines their black or dark color. It's used as a colorant in tablets and capsules to help identify the product and make it visually distinctive.
  • UNII 2G86QN327L
    Gelatin is a protein derived from animal collagen, commonly used in medicines as a gelling agent and capsule material. It helps create soft or hard capsule shells that hold and release medication, and can also thicken liquid formulations.
  • UNII 70097M6I30
    Magnesium stearate is a salt made from magnesium and stearic acid, a fatty substance. It's used in tablets and capsules as a lubricant and glidant to help ingredients flow smoothly during manufacturing and prevent sticking.
  • UNII WZH3C48M4T
    Potassium hydroxide is a strong alkaline chemical used in medicines to adjust and maintain the pH level of liquid formulations, helping keep the product stable and the active ingredients effective.
  • UNII 6DC9Q167V3
    Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
  • UNII 46N107B71O
    Shellac is a natural resin secreted by the lac beetle. It's used as a coating on tablets and capsules to control how quickly the medicine dissolves and to improve appearance and stability.
  • UNII ETJ7Z6XBU4
    Silicon dioxide is a naturally occurring mineral used as a glidant and anti-caking agent. It helps powder ingredients flow smoothly and prevents clumping during manufacturing and storage.
  • UNII 368GB5141J
    A detergent and foaming agent derived from coconut or palm oil. In medications, it helps break down and mix oil and water-based ingredients, aids in tablet disintegration, and improves how the drug dissolves and spreads in the mouth or digestive system.
  • UNII 5856J3G2A2
    A starch-based powder made from potatoes and processed with sodium. It acts as a disintegrant, helping the tablet or capsule break apart quickly in the stomach so the medicine can be absorbed.
  • UNII 15FIX9V2JP
    Titanium dioxide is a bright white mineral powder commonly used as a colorant and opacifying agent. It makes pills and tablets white or lighter in color and helps make coatings non-transparent.

18 inactive ingredients listed in the exact product block matched to this NDC.

Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed — ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerZydus Lifesciences Limited
Application holderZYDUS PHARMACEUTICALS USA INC
FDA applicationANDA205115 (ANDA)
Labeler code65841
First marketedMar 2016
Product typeHuman Prescription Drug
Portfolio720 products on file

More NDCs from Zydus Lifesciences Limited labeler code 65841

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

Full prescribing information FDA SPL

The complete FDA label for this product — the official prescribing information, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
📄 Package Label / Principal Display Panel
📄 Package Label / Principal Display Panel 64 words ▾

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL NDC 65841-821-01 in bottle of 100 Capsules Doxycycline Capsules USP, 50 mg Rx Only 100 Capsules NDC 65841-822-01 in bottle of 100 Capsules Doxycycline Capsules USP, 75 mg Rx Only 100 Capsules NDC 65841-823-01 in bottle of 100 Capsules Doxycycline Capsules USP, 100 mg Rx Only 100 Capsules Doxycycline Capsules 50 mg Doxycycline Capsules 75 mg Doxycycline Capsules 100 mg

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

About this NDC listing & data coverage

Finished prescription product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos ✓ Available
Inactive ingredients (structured) ✓ Available
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data ✓ Available
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Zydus Lifesciences Limited. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 7 other package presentations of this same product, including 30 capsules (65841-0823-06), 50 capsules (65841-0823-18), 90 capsules (65841-0823-16). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Zydus Lifesciences Limited is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as a prescription product, so it is dispensed under a prescriber's order. Your pharmacist can tell you whether any over-the-counter forms of the same medication exist.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 65841-0822-01 · Zydus 65841-0824-01 · Zydus →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.