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Aspirin 325 mg Tablet, Film Coated, 100-count — NDC 70000-0253-02 package photo
Label image from the product's FDA listing (DailyMed) — may show a different pack size or an older label revision.

Aspirin 325 mg Tablet, Film Coated, 100-count — NDC 70000-0253-2 (Billing 70000-0253-02)

by Cardinal Health 110, LLC. DBA Leader · 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC

This is a package of 100 tablets of Aspirin 325 mg Tablet, Film Coated from Cardinal Health 110, LLC. DBA Leader, marketed since Feb 1996 and currently FDA-listed; retail pharmacies pay about $0.0166 per tablet (NADAC).

NDC 70000-0253-02
🏷️ FDA NDC (as labeled) 70000-0253-2 billing pads the package segment with a zero
This package
Contains100-count Cost per ea$0.0166 NADAC Per package$1.66 / 100 tablets Pack sizes2 compare ↓
Also priced by: Medicaid pays $0.1787/unit — full pricing hub ↓
Product page 70000-0253-04 Also comes in: 500 tablets 70000-0253-4
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

NDC database record

One package, one record: these facts belong to NDC 70000-0253-2 alone.

Record
FDA NDC Directory package listing · Human OTC drug
Code segments
70000 labeler · 0253 product · 2 package
Package marketed since
Feb 10, 1996
Sample package
No — commercial package
Listing certified through
Dec 31, 2027
Billing quantity
100 EA per package
Barcode (UPC)
0096295131475
Medicaid fills, this package
1,219 prescriptions in the last four reported quarters
FDA record last changed
Jul 24, 2026

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 70000-0253-2
Product NDC 70000-0253
11-digit billing NDC 70000025302
NCPDP billing unit EA — each (per item)
RxCUI 212033
UNII R16CO5Y76E
UPC 0096295131475
Application # M013
SPL Set ID 318cc982-23a9-4804-b6fb-248f772d7a38
Established class (EPC) Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor
Mechanism of action Cyclooxygenase Inhibitors
Physiologic effect Decreased Prostaglandin Production; Decreased Platelet Aggregation
Chemical class Anti-Inflammatory Agents, Non-Steroidal
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 1996-02-10
Route ORAL
Dosage form TABLET, FILM COATED
Substance ASPIRIN

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 64100010000315
GPI class Aspirin
GCN Seq No 004376
GCN 16701
HICL code 001820
Ingredient (HICL) Aspirin
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H3
Therapeutic class — intermediate (HIC2) Analgesics
HIC3 code H3D
Therapeutic class — specific (HIC3) Analgesic/Antipyretics, Salicylates
AHFS code 20:12.18.00
AHFS class Platelet-Aggregation Inhibitors
FDB label name ASPIRIN 325 MG TABLET
FDB brand name Aspirin
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 004376
  • GCN: 16701
  • GPI-14 (Medi-Span): 64100010000315
  • HICL (First Databank): 001820
  • AHFS class code: 20:12.18.00
  • RxCUI (RxNorm): 212033
Why two NDCs? The FDA registers this code as 70000-0253-2 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70000-0253-02. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Platelet Aggregation Inhibitor class.

Pharmacologic class Platelet Aggregation Inhibitor, Nonsteroidal Anti-inflammatory Drug
Drug family (ATC) Other agents for local oral treatment, Platelet aggregation inhibitors excl. heparin, Salicylic acid and derivatives
How it works Cyclooxygenase Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name ASPIRIN 325 MG TABLET Ingredient Aspirin
📖 What it is MedlinePlus · NLM

Aspirin is used to: reduce fever relieve mild to moderate pain and inflammation prevent heart attacks, strokes or mini-strokes reduce the risk of death in people who are experiencing or who have had a heart attack Aspirin is in a group of medications called salicylates. It works by blocking natural substances that cause fever, pain, swelling, and blood clots. Aspirin is also available in combination with other medications such as pain relievers and cough and cold medications. This monograph only includes information about the use of aspirin alone. If you are taking a combination product,...

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Aspirin is used to temporarily relieve common minor pains — things like headaches, backaches, muscle aches, toothaches, menstrual cramps, and discomfort from a cold — and to reduce...
  • Generally, no — aspirin should not be given to children under 12. More importantly, children and teenagers who have or are recovering from chickenpox or a flu-like illness should n...
  • Yes, stomach upset, heartburn, and nausea are real possibilities with aspirin. Taking it with a full glass of water helps. Some people tolerate enteric-coated or delayed-release fo...
  • Does aspirin upset your stomach? What can I do about it?
📖 Read our full Aspirin guide →
3
Nutrient depletion considerations

Aspirin may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Aspirin nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eaPer package
Retail pharmacies payNADAC · weekly $0.017 $1.66 / 100 tablets
Medicaid paysCMS SDUD · 12 mo $0.1787 $17.87 / 100 tablets
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per ea) — tap or hover for the price & month
Mar 2022 Oct 2022 Feb 2026 Sep 2026 $0.017 $0.010
▲ Up 64% over the last 22 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Per unit Per pack Marketing startMarketing endStatus
70000-0253-02 You're viewing this 100 TABLET, FILM COATED in 1 BOTTLE, PLASTIC $0.0166 / ea $1.66 1996-02-10 — Active
70000-0253-04 70000-0253-4 Main listing 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC $0.0153 / ea $7.65 1996-02-10 — Active

You're viewing the smallest of 2 pack sizes for this product.

Per ea, this pack runs about 8% above the cheapest pack (500-count, $0.0153 vs $0.0166 NADAC).

In Medicaid, this is the most-dispensed pack of this product — about 54% of fills over the last four reported quarters. See all packs ↓

Pack size FAQ

What quantity is in this package?
This is a 100-count package — 100 tablet, film coated in 1 bottle, plastic.
How does this package differ from NDC 70000-0253-04?
Both are Aspirin 325 mg Tablet, Film Coated — the drug itself is identical. This page's package is the 100-count one, while NDC 70000-0253-04 is the 500 tablets package. Per-ea NADAC also differs: $0.0166 here vs $0.0153 for the 500 tablets pack.
What NDC number is used to bill for this package of Aspirin 325 mg Tablet, Film Coated?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Prices are the latest CMS NADAC pharmacy acquisition cost per NDC; per-pack figures are per-unit × pack quantity, shown only when the pack is denominated in the same measure NADAC prices.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Aspirin 325 mg 00536-1054-05 Rugby 500 tablets $0.011 — Discontinued save 33%
Aspirin 325 mg 63868-0352-03 CHAIN 300 tablets $0.011 — Discontinued save 33%
Aspirin 325 mg 46122-0691-78 Amerisource 100 tablets $0.017 — Availability likely —
McKesson Aspirin 325 mg 68599-1311-03 McKesson 2 tablets $0.017 — Availability likely —
Aspirin 325 mgthis 70000-0253-02 Cardinal 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 70677-1189-01 Strategic 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 83324-0066-01 Chain 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 83324-0205-01 CHAIN 100 tablets $0.017 — Availability likely —
Tri-Buffered Aspirin 325 mg 00904-2015-59 Major 100 tablets $0.021 — Discontinued +24%
Buffered Aspirin 325 mg 70000-0147-01 Cardinal 130 tablets $0.021 — Availability likely +24%
Regular Strength Aspirin 325 mg 70000-0014-01 CARDINAL 300 tablets $0.022 — Availability likely +33%
Bayer Genuine Aspirin 325 mg 00280-2000-01 Bayer 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 00363-0157-14 Walgreen 500 tablets — — FDA listed —
Physicians Care Aspirin 325 mg 00924-0105-00 Acme 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 00924-6020-02 Acme 100 tablets — — FDA listed —
Regular strength aspirin 325 mg 11673-0188-53 TARGET 500 tablets — — FDA listed —
Pain Relief Aspirin 325 mg 11822-0157-02 Rite 100 tablets — — FDA listed —
Aspirin 325 mg 17714-0010-01 Advance 100 tablets — — FDA listed —
Aspirin 325 mg 21130-0758-53 BETTER 500 tablets — — FDA listed —
Aspirin 325 mg 21130-0957-14 Better 500 tablets — — Discontinued —
Aspirin 325 mg 36800-0157-12 Topco 100 tablets — — FDA listed —
Aspirin 325 mg 37808-0157-12 H 100 tablets — — Discontinued —
Aspirin 325 mg 37835-0577-01 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 37835-0738-02 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 41163-0157-12 United 100 tablets — — FDA listed —
Regular Strength Aspirin 325 mg 41226-0011-32 Kroger 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 41250-0118-11 Meijer 100 tablets — — Discontinued —
Aspirin Regular Strength 325 mg 41520-0157-78 FOODHOLD 100 tablets — — FDA listed —
ASPIRIN 325 mg 42507-0018-11 HYVEE 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 47682-0456-47 Unifirst 2 tablets — — FDA listed —
Medique at Home Aspirin 325 mg 47682-0533-33 Unifirst 2 tablets — — FDA listed —
Medique Products Aspirin 325 mg 47682-0616-13 Unifirst 2 tablets — — FDA listed —
Medi-First Aspirin 325 mg 47682-0617-13 Unifirst 2 tablets — — FDA listed —
Medi-First Plus Aspirin 325 mg 47682-0618-33 Unifirst 2 tablets — — FDA listed —
Aspirin 325 mg 49035-0157-06 Wal-Mart 200 tablets — — Discontinued —
Unishield Aspirin 325 mg 49314-1163-03 Unishield 2 tablets — — FDA listed —
Aspirin 325 mg 49483-0011-00 TIME 100000 tablets — — FDA listed —
Bufferin Regular Strength Pain Relief 325 mg 50066-0610-13 Genomma 130 tablets — — FDA listed —
Aspirin 325 mg 50090-6195-08 A-S 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0005-06 JC 24 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0006-06 JC 12 tablets — — FDA listed —
Aspirin 325 mg 50332-0139-03 HART 50 tablets — — FDA listed —
Aspirin 325 mg 50804-0157-12 Geiss, 100 tablets — — FDA listed —
Aspirin 325 mg 50844-0157-12 L.N.K. 100 tablets — — FDA listed —
Coated Aspirin 325 mg 50844-0254-12 L.N.K. 100 tablets — — FDA listed —
Aspirn 325 mg 51662-1583-01 HF 2 tablets — — FDA listed —
Aspirin 325 mg 53185-0249-12 Athlete's 100 tablets — — FDA listed —
Aspirin 325 mg 53943-0157-12 Discount 100 tablets — — FDA listed —
Geritrex Aspirin 325 mg 54162-0940-90 Geritrex 1000 tablets — — FDA listed —
Aspirin 325 mg 54738-0541-01 Richmond 100 tablets — — FDA listed —
Aspirin 325 mg 55301-0157-12 ARMY 100 tablets — — FDA listed —
Rapidol Aspirin 325 mg 55758-0363-60 Pharmadel 60 tablets — — FDA listed —
Aspirin 325 mg 55910-0249-29 DOLGENCORP, 150 tablets — — FDA listed —
aspirin 325 mg 56062-0118-11 PUBLIX 100 tablets — — FDA listed —
Aspirin 325 mg 57243-0157-12 Salado 100 tablets — — FDA listed —
Aspirin 325 mg 57344-0018-11 AAA 100 tablets — — FDA listed —
Aspirin 325 mg 57896-0901-01 Geri-Care 100 tablets — — FDA listed —
Aspirin 325 mg 58228-0071-01 PROSTAT 20000 tablets — — FDA listed —
Travel Savvy Aspirin 325 mg 59961-0616-15 Bellegrove 2 tablets — — FDA listed —
Aspirin 325 mg 60760-0930-24 St. 24 tablets — — Discontinued —
Direct Safety Aspirin 325 mg 61245-0616-13 Direct 2 tablets — — FDA listed —
Aspirin 325 mg 63941-0118-19 VALU 300 tablets — — FDA listed —
Aspirin NSAID 325 mg 63941-0157-12 Valu 100 tablets — — FDA listed —
Aspirin 325 mg 63941-0249-12 Valu 100 tablets — — Discontinued —
Circle K Aspirin 325 325 mg 66715-5504-04 Lil 100 tablets — — FDA listed —
BAYER Aspirin Original, TRAVEL BASIX 325 mg 66715-6426-02 Lil' 4 tablets — — FDA listed —
BAYER Aspirin Original, CVP HEALTH 325 mg 66715-6526-02 Lil' 4 tablets — — FDA listed —
Lil Drug Store Aspirin 325 325 mg 66715-6840-06 Lil 100 tablets — — FDA listed —
Bayer 325 mg 66715-9726-02 Lil' 4 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 67751-0129-01 Navajo 2 tablets — — FDA listed —
Aspirin 325 mg 68788-8256-01 Preferred 100 tablets — — FDA listed —
Aspirin 325 mg 68998-0018-11 Marc 100 tablets — — FDA listed —
Aspirin 325 mg 69168-0312-01 Allegiant 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0158-01 Trifecta 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0173-01 Trifecta 1000 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 69517-0002-05 HealthLife 500 tablets — — Discontinued —
Aspirin 325 mg 69732-0008-01 Hi-Tech 200 tablets — — FDA listed —
ULINE Aspirin 325 mg 69790-0616-33 ULINE 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 70264-0013-01 R 100 tablets — — FDA listed —
Aspirin Packs 325 mg 70385-2006-02 Sina 2 tablets — — FDA listed —
Tri-Buffered Aspirin 325 mg 71205-0517-30 Proficient 30 tablets — — FDA listed —
Aspirin 325 mg 71679-0302-00 Health 28500 tablets — — FDA listed —
Aspirin 325 mg 72036-0018-11 HARRIS 100 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 72476-0018-11 RETAIL 100 tablets — — FDA listed —
Aspirin 325 mg 72789-0574-25 PD-Rx 25 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 73057-0365-08 Ulai 100 tablets — — FDA listed —
Thompson Aspirin 325 mg 73408-0618-33 Thompson 2 tablets — — FDA listed —
Aspirin 50 CT 325 mg 73598-1112-01 JHK 50 tablets — — FDA listed —
Aspirin 325 mg 77333-0050-20 Gendose 1 tablet — — FDA listed —
Aspirin 325 mg 79481-1570-01 Meijer 100 tablets — — FDA listed —
Aspirin 325 mg 82804-0167-60 Proficient 60 tablets — — FDA listed —
Aspirin 325 mg 82804-0237-04 Proficient 4 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 83586-0115-01 HHH 100 tablets — — FDA listed —
Aspirin 325 mg 85111-0901-10 RMT 1000 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 85237-1828-01 Select 1 tablet — — FDA listed —
Medique at Home Aspirin 325 mg 85766-0125-01 Sportpharm 2 tablets — — FDA listed —
Aspirin 325 mg 17714-0011-01 Advance 100 tablets — — FDA listed —
Aspirin 325 mg 54738-0111-01 Richmond 100 tablets — — FDA listed —
Aspirin 325 mg 71610-0034-65 Aphena 100 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 57896-0921-01 Geri-Care 100 tablets — — FDA listed —
Drug Mart Effervescent Pain Relief 325 mg 53943-0431-36 Discount 2 tablets — — FDA listed —
Dollar General Effervescent Pain Reliever 325 mg 55910-0040-36 Dolgencorp, 2 tablets — — FDA listed —
Publix Fast Relief Effervescent - Original Flavor 325 mg 56062-0358-36 PUBLIX 2 tablets — — FDA listed —
Best Choice Effervescent Pain Reliever 36 325 mg 63941-0241-12 VALU 2 tablets — — FDA listed —
Aspirin 325 mg 85111-0921-10 RMT 1000 tablets — — FDA listed —
HEB Effervescent Pain Relief 325 mg 37808-0861-36 H. 2 tablets — — FDA listed —
Signature Select Effervescent Pain Relief 325 mg 21130-0295-36 Safeway 2 tablets — — FDA listed —
TopCare Effervescent Pain Relief 325 mg 36800-0789-36 TOPCO 2 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 60760-0799-24 St. 24 tablets — — Discontinued —
Aspirin 325 mg 80425-0293-01 Advanced 30 tablets — — FDA listed —
Aspirin 325 Mg Ec 71335-1800-01 Bryant 30 tablets — — FDA listed —
Aspirin 325 mg 72789-0556-07 PD-Rx 7 tablets — — FDA listed —
Aspirin 325 mg 84269-2501-01 Wildman 2 tablets — — FDA listed —
Winco Foods Effervescent Pain Relief 325 mg 67091-0448-36 Winco 2 tablets — — FDA listed —
Family Wellness Pain Reliever 325 mg 55319-0870-36 FAMILY 2 tablets — — FDA listed —
Bayer Aspirin Regimen enteric coated 325 mg 00280-2110-10 Bayer 100 tablets — — FDA listed —
Aspirin 325 mg 67091-0110-10 WinCo 100 tablets — — Discontinued —
Aspirin 325 Mg Ec 69618-0015-01 Reliable 100 tablets — — FDA listed —
Aspirin 325 Mg Ec 71205-0318-20 Proficient 20 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 17856-0922-01 ATLANTIC 1 tablet — — FDA listed —
Aspirin 325 mg 37808-0174-32 H-E-B 300 tablets — — FDA listed —
CVS Effervescent Pain Reliever 325 mg 51316-0359-36 CVS 2 tablets — — FDA listed —
Aspirin 325 mg 59779-0157-14 CVS 500 tablets — — FDA listed —
Meijer Effervescent Pain Relief 325 mg 79481-0073-06 Meijer 2 tablets — — FDA listed —
Quality Choice Effervescent Pain Relief 325 mg 83324-0018-36 CHAIN 2 tablets — — FDA listed —
Aspirin 325 mg 51662-1494-01 HF 100 tablets — — FDA listed —
Aspirin 325 mg 00363-6453-53 WALGREENS 500 tablets — — FDA listed —
Aspirin 325 mg 81522-0018-11 FSA 100 tablets — — FDA listed —
Equaline Effervescent Pain Reliever 325 mg 41163-0741-36 UNITED 2 tablets — — FDA listed —
Good Sense Effervescent Pain Relief 325 mg 50804-0422-36 Perrigo 2 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 71335-0513-01 Bryant 30 tablets — — FDA listed —
Market Basket Effervescent Pain Relief 325 mg 53942-0883-36 DEMOULAS 2 tablets — — FDA listed —
Ecotrin Regular Strength 325 mg 63029-0302-01 Medtech 300 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
1996
On the market since
Feb 1996
📍
2026
Currently FDA-listed
30 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color white
ShapeRound
ImprintAspirin;44;157
Size1 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerCardinal Health 110, LLC. DBA Leader
FDA applicationM013 (OTC MONOGRAPH DRUG)
Labeler code70000
First marketedFeb 1996
Product typeHuman Otc Drug
Portfolio163 products on file

More NDCs from Cardinal Health 110, LLC. DBA Leader labeler code 70000

The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 18 words ▾

Uses temporarily relieves: minor pain of arthritis headache muscle pain menstrual pain toothache pain and fever of colds

⏱️ Dosage and Administration 62 words ▾

Directions do not take more than directed drink a full glass of water with each dose adults and children 12 years and over: take 1 or 2 tablets every 4 hours or 3 tablets every 6 hours not to exceed 12 tablets in 24 hours unless directed by a doctor children under 12 years: do not use unless directed by a doctor

⚠️ Warnings ~2 min read ▾

Warnings Reye’s syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction, which may include: facial swelling shock hives asthma (wheezing) Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if you are age 60 or older take a blood thinning (anticoagulant) or steroid drug have 3 or more alcoholic drinks every day while using this product have had stomach ulcers or bleeding problems take more or for a longer time than directed take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others] Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you are taking a diuretic you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you have asthma Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis Stop use and ask a doctor if an allergic reaction occurs.

Seek medical help right away. you experience any of the following signs of stomach bleeding: vomit blood have bloody or black stools feel faint have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

📦 Storage and Handling 17 words ▾

Other information use by expiration date on package store at 25°C (77°F); excursions permitted between 15°-30°C (59°-86°F)

🧪 Active Ingredient 12 words ▾

Active ingredient (in each tablet) Aspirin 325 mg (NSAID)* *nonsteroidal anti-inflammatory drug

🧪 Inactive Ingredients 9 words ▾

Inactive ingredients corn starch, hypromellose, polyethylene glycol, propylene glycol

🎯 Purpose 4 words ▾

Purpose Pain reliever/fever reducer

📄 Do Not Use 31 words ▾

Do not use if you are allergic to aspirin or any other pain reliever/fever reducer if you have ever had an allergic reaction to this product or any of its ingredients

📄 Ask a Doctor Before Use If 42 words ▾

Ask a doctor before use if stomach bleeding warning applies to you you have a history of stomach problems, such as heartburn you are taking a diuretic you have high blood pressure, heart disease, liver cirrhosis, or kidney disease you have asthma

📄 Ask a Doctor or Pharmacist Before Use If 18 words ▾

Ask a doctor or pharmacist before use if you are taking a prescription drug for gout diabetes arthritis

📄 Stop Use and Ask a Doctor If 87 words ▾

Stop use and ask a doctor if an allergic reaction occurs. Seek medical help right away. you experience any of the following signs of stomach bleeding: vomit blood have bloody or black stools feel faint have stomach pain that does not get better ringing in the ears or a loss of hearing occurs pain gets worse or lasts more than 10 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur These could be signs of a serious condition.

🤰 If Pregnant or Breast-Feeding 47 words ▾

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

📄 Keep Out of Reach of Children 21 words ▾

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.

📄 Questions or Comments 4 words ▾

Questions or comments? 1-800-200-6313

📄 Package Label / Principal Display Panel 119 words ▾

Principal display panel LEADER ™ NDC 70000-0253-2 Genuine Aspirin Tablets , 325 mg | Pain Reliever Fever Reducer (NSAID) Actual Size 100 TABLETS COMPARE TO GENUINE BAYER ® ASPIRIN active ingredient † 100% Money Back Guarantee TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING † This product is not manufactured or distributed by Bayer AG, owner of the registered trademark Genuine Bayer ® Aspirin. 50844 REV0122B15712 ©2022 CARDINAL HEALTH, LEADER, and LOGOs are trademarks of Cardinal Health.

All other marks are the property of their respective owners. 100% Money Back Guarantee Return to place of purchase if not satisfied. DISTRIBUTED BY CARDINAL HEALTH, DUBLIN, OHIO 43017 www.myleader.com 1-800-200-6313 Leader 44-157 Leader 44-157

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Medicaid utilization & spend

📍 This exact package only: Medicaid data is reported per full 11-digit NDC — labeler, product and pack size — so every number here is for this package alone, not the drug overall. Other pack sizes report separately.
💊 Pharmacy benefit only: These are Medicaid outpatient pharmacy claims, billed by NDC. They exclude the medical benefit — clinic- or hospital-administered drugs billed under HCPCS J-codes — so drugs used mostly that way (e.g. Avastin, Lucentis, Keytruda) can look low or missing here. That’s expected, not an error.
📅 Q1 2025 – Q1 2026 · 5 quarters of data
ⓘ The newest quarter is usually incomplete when first published; states restate recent quarters in later CMS releases, so the latest figures typically revise upward. State coverage-policy changes can also shift quarter-to-quarter totals.
Prescriptions last 4 qtrs
1.2K
Units reimbursed last 4 qtrs
43.1K
Gross reimbursed last 4 qtrs
$7.7K
Avg / prescription
$6.31
Avg / unit
$0.1787
Latest quarter Q1 2026
297Rx
Medicaid pays / ea
$0.1787
gross reimbursed
vs
NADAC / ea
$0.0166
acquisition cost
=
Spread
+$0.1621
+977% vs cost
What Medicaid paid per ea (before rebates; includes the pharmacy’s dispensing fee) compared with NADAC — the average price pharmacies pay to buy the drug. A positive spread means Medicaid reimbursed more than the purchase price, before manufacturer rebates.
Fee-for-service vs managed care ⓘ
35% FFS 65% MCO
Fee-for-service · 421 Rx Managed care · 798 Rx
State Medicaid map
Alaska: no data reported AK Maine: no data reported ME Washington: no data reported WA Idaho: no data reported ID Montana: no data reported MT North Dakota: no data reported ND Minnesota: 6,258 units · 109 per 100k residents MN Wisconsin: 811 units · 13.7 per 100k residents WI Michigan: 2,756 units · 27.5 per 100k residents MI New York: 5,899 units · 30.1 per 100k residents NY Vermont: no data reported VT New Hampshire: no data reported NH Oregon: no data reported OR Nevada: no data reported NV Wyoming: no data reported WY South Dakota: no data reported SD Iowa: no data reported IA Illinois: no data reported IL Indiana: 2,395 units · 34.9 per 100k residents IN Ohio: no data reported OH Pennsylvania: 2,626 units · 20.3 per 100k residents PA New Jersey: no data reported NJ Massachusetts: no data reported MA California: 6,684 units · 17.2 per 100k residents CA Utah: no data reported UT Colorado: no data reported CO Nebraska: no data reported NE Missouri: no data reported MO Kentucky: 1,730 units · 38.2 per 100k residents KY West Virginia: no data reported WV Virginia: 725 units · 8.3 per 100k residents VA Maryland: 1,212 units · 19.6 per 100k residents MD Connecticut: no data reported CT Rhode Island: no data reported RI Arizona: no data reported AZ New Mexico: no data reported NM Kansas: 863 units · 29.4 per 100k residents KS Arkansas: no data reported AR Tennessee: no data reported TN North Carolina: no data reported NC South Carolina: no data reported SC Delaware: no data reported DE Oklahoma: no data reported OK Louisiana: no data reported LA Mississippi: no data reported MS Alabama: no data reported AL Georgia: no data reported GA D.C.: no data reported DC Hawaii: no data reported HI Texas: no data reported TX Florida: no data reported FL
Units reimbursed · per 100k residents
8.3109
gray = no data reported ⓘ
Colors are per 100,000 residents, so big states don’t automatically dominate. Tap or hover a state for its actual totals.
Tap or hover a state
…for its Medicaid breakdown
🏆 Top states by units · per 100k residents
1 Minnesota 109 /100k
2 Kentucky 38.2 /100k
3 Indiana 34.9 /100k
4 New York 30.1 /100k
5 Kansas 29.4 /100k
6 Michigan 27.5 /100k
7 Pennsylvania 20.3 /100k
8 Maryland 19.6 /100k
National units — by quarter
💵 About the dollar figures: “reimbursed” is what Medicaid paid pharmacies before confidential manufacturer rebates, so the program’s real net cost is lower than these numbers. Fee-for-service and managed-care claims are combined unless split above. Source: CMS State Drug Utilization Data; per-100k rates use 2023 Census population estimates.

Medicaid utilization by pack size

Medicaid (SDUD) totals over the four most recent reported quarters for every package size of this drug — handy when a specific package (e.g. a starter/titration pack) carries little or no Medicaid volume on its own.
100 tablets this page70000-0253-02 1,219 Rx · $7,691
500 tablets70000-0253-04 1,033 Rx · $7,362
Drug total (last 4 qtrs): 2,252 Rx · 80,096 units · $15,053 gross reimbursed
Tap a pack size to open its page. Source: CMS State Drug Utilization Data, last 4 quarters.
← 70000-0247-01 · Cardinal 70000-0260-01 · Cardinal →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.