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Tri-Buffered Aspirin 325 mg Tablet, Film Coated, 90-count — NDC 71205-517-90 (Billing 71205-0517-90)

by Proficient Rx LP · 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC

This is a package of 90 tablets of Tri-Buffered Aspirin 325 mg Tablet, Film Coated from Proficient Rx LP, marketed since Mar 1990 and currently FDA-listed.

NDC 71205-0517-90
🏷️ FDA NDC (as labeled) 71205-517-90 billing pads the product segment with a zero
This package
Contains90-count Pack sizes3 compare ↓
Product page 71205-0517-30 Also comes in: 30 tablets 71205-517-30 60 tablets 71205-517-60
OTC On market Non-controlled ⇄ Compare with another NDC
🗂️ FDA directory synced Oct 1, 2026 · this listing last changed Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

Identity & classification

Regulatory identifiers FDA, NLM and CMS codes for this package

FDA NDC (as labeled) 71205-517-90
Product NDC 71205-517
11-digit billing NDC 71205051790
RxCUI 212033
UNII R16CO5Y76E
UPC 0371205517304
Application # M013
SPL Set ID 640c3311-2abf-40b2-82b9-9fe4d8c1cf1d
Established class (EPC) Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor
Mechanism of action Cyclooxygenase Inhibitors
Physiologic effect Decreased Prostaglandin Production; Decreased Platelet Aggregation
Chemical class Anti-Inflammatory Agents, Non-Steroidal
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 1990-03-30
Route ORAL
Dosage form TABLET, FILM COATED
Substance ASPIRIN

Drug-database identifiers Medi-Span GPI and First Databank GCN / HICL / AHFS classification

GPI-14 64109902040320
GPI class Aspirin Buf(CaCarb-MgCarb-MgO)
GCN Seq No 027896
GCN 71417
HICL code 011792
Ingredient (HICL) Aspirin/Calcium Carb/Magnesium
HIC1 code H
Therapeutic class — broad (HIC1) Nervous System (Except Autonomic)
HIC2 code H3
Therapeutic class — intermediate (HIC2) Analgesics
HIC3 code H3D
Therapeutic class — specific (HIC3) Analgesic/Antipyretics, Salicylates
AHFS code 20:12.18.00
AHFS class Platelet-Aggregation Inhibitors
FDB label name TRI-BUFFERED ASPIRIN 325 MG TB
FDB brand name Tri-Buffered Aspirin
Legend status O — Over-the-counter (OTC) drug or device
Quick answers
  • GSN (GCN sequence number): 027896
  • GCN: 71417
  • GPI-14 (Medi-Span): 64109902040320
  • HICL (First Databank): 011792
  • AHFS class code: 20:12.18.00
  • RxCUI (RxNorm): 212033
Why two NDCs? The FDA registers this code as 71205-517-90 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 71205-0517-90. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

RxNorm drug class

This medicine belongs to the Platelet Aggregation Inhibitor class.

Pharmacologic class Platelet Aggregation Inhibitor, Nonsteroidal Anti-inflammatory Drug
Drug family (ATC) Other agents for local oral treatment, Platelet aggregation inhibitors excl. heparin, Salicylic acid and derivatives
How it works Cyclooxygenase Inhibitors
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.

Clinical

Label name TRI-BUFFERED ASPIRIN 325 MG TB Ingredient Aspirin/Calcium Carb/Magnesium
📗 Our plain-language guide HelloPharmacist
  • Aspirin is used to temporarily relieve common minor pains — things like headaches, backaches, muscle aches, toothaches, menstrual cramps, and discomfort from a cold — and to reduce...
  • Generally, no — aspirin should not be given to children under 12. More importantly, children and teenagers who have or are recovering from chickenpox or a flu-like illness should n...
  • Yes, stomach upset, heartburn, and nausea are real possibilities with aspirin. Taking it with a full glass of water helps. Some people tolerate enteric-coated or delayed-release fo...
  • Does aspirin upset your stomach? What can I do about it?
📖 Read our full Aspirin guide →
3
Nutrient depletion considerations

Aspirin may be associated with lower levels of 3 nutrients — worth a chat with your pharmacist, not a cause for alarm.

🧪 Full Aspirin nutrient depletion report →
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer eachPer package
Retail pharmacies payNADAC · weekly Not in the retail survey — common for institutional, discontinued, or low-volume packs.
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
ℹ️
No price is published for this exact package yet. CMS surveys NADAC per package size, so a different pack of the same drug often has one.
Try another pack size: 30 tablets 60 tablets
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

Packaging — all sizes for this product

Package NDCDescription Marketing startMarketing endStatus
71205-0517-30 71205-517-30 Main listing 30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2020-12-30 — Active
71205-0517-60 71205-517-60 60 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2020-12-30 — Active
71205-0517-90 You're viewing this 90 TABLET, FILM COATED in 1 BOTTLE, PLASTIC 2020-12-30 — Active

You're viewing the largest of 3 pack sizes for this product.

Pack size FAQ

What quantity is in this package?
This is a 90-count package — 90 tablet, film coated in 1 bottle, plastic.
How does this package differ from NDC 71205-0517-30?
Both are Tri-Buffered Aspirin 325 mg Tablet, Film Coated — the drug itself is identical. This page's package is the 90-count one, while NDC 71205-0517-30 is the 30 tablets package.
What NDC number is used to bill for this package of Tri-Buffered Aspirin 325 mg Tablet, Film Coated?
Use the 11-digit billing form listed in the identifiers section of this page. Pharmacy and medical claims use the 11-digit form; the FDA label may print a shorter form of the same code.

Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Aspirin 325 mg 00536-1054-05 Rugby 500 tablets $0.011 — Discontinued —
Aspirin 325 mg 63868-0352-03 CHAIN 300 tablets $0.011 — Discontinued —
Aspirin 325 mg 46122-0691-78 Amerisource 100 tablets $0.017 — Availability likely —
McKesson Aspirin 325 mg 68599-1311-03 McKesson 2 tablets $0.017 — Availability likely —
Aspirin 325 mg 70000-0253-02 Cardinal 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 70677-1189-01 Strategic 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 83324-0066-01 Chain 100 tablets $0.017 — Availability likely —
Aspirin 325 mg 83324-0205-01 CHAIN 100 tablets $0.017 — Availability likely —
Tri-Buffered Aspirin 325 mg 00904-2015-59 Major 100 tablets $0.021 — Discontinued —
Buffered Aspirin 325 mg 70000-0147-01 Cardinal 130 tablets $0.021 — Availability likely —
Regular Strength Aspirin 325 mg 70000-0014-01 CARDINAL 300 tablets $0.022 — Availability likely —
Bayer Genuine Aspirin 325 mg 00280-2000-01 Bayer 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 00363-0157-14 Walgreen 500 tablets — — FDA listed —
Physicians Care Aspirin 325 mg 00924-0105-00 Acme 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 00924-6020-02 Acme 100 tablets — — FDA listed —
Regular strength aspirin 325 mg 11673-0188-53 TARGET 500 tablets — — FDA listed —
Pain Relief Aspirin 325 mg 11822-0157-02 Rite 100 tablets — — FDA listed —
Aspirin 325 mg 17714-0010-01 Advance 100 tablets — — FDA listed —
Aspirin 325 mg 21130-0758-53 BETTER 500 tablets — — FDA listed —
Aspirin 325 mg 21130-0957-14 Better 500 tablets — — Discontinued —
Aspirin 325 mg 36800-0157-12 Topco 100 tablets — — FDA listed —
Aspirin 325 mg 37808-0157-12 H 100 tablets — — Discontinued —
Aspirin 325 mg 37835-0577-01 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 37835-0738-02 Bi-Mart 100 tablets — — FDA listed —
Aspirin 325 mg 41163-0157-12 United 100 tablets — — FDA listed —
Regular Strength Aspirin 325 mg 41226-0011-32 Kroger 300 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 41250-0118-11 Meijer 100 tablets — — Discontinued —
Aspirin Regular Strength 325 mg 41520-0157-78 FOODHOLD 100 tablets — — FDA listed —
ASPIRIN 325 mg 42507-0018-11 HYVEE 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 47682-0456-47 Unifirst 2 tablets — — FDA listed —
Medique at Home Aspirin 325 mg 47682-0533-33 Unifirst 2 tablets — — FDA listed —
Medique Products Aspirin 325 mg 47682-0616-13 Unifirst 2 tablets — — FDA listed —
Medi-First Aspirin 325 mg 47682-0617-13 Unifirst 2 tablets — — FDA listed —
Medi-First Plus Aspirin 325 mg 47682-0618-33 Unifirst 2 tablets — — FDA listed —
Aspirin 325 mg 49035-0157-06 Wal-Mart 200 tablets — — Discontinued —
Unishield Aspirin 325 mg 49314-1163-03 Unishield 2 tablets — — FDA listed —
Aspirin 325 mg 49483-0011-00 TIME 100000 tablets — — FDA listed —
Bufferin Regular Strength Pain Relief 325 mg 50066-0610-13 Genomma 130 tablets — — FDA listed —
Aspirin 325 mg 50090-6195-08 A-S 100 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0005-06 JC 24 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 50269-0006-06 JC 12 tablets — — FDA listed —
Aspirin 325 mg 50332-0139-03 HART 50 tablets — — FDA listed —
Aspirin 325 mg 50804-0157-12 Geiss, 100 tablets — — FDA listed —
Aspirin 325 mg 50844-0157-12 L.N.K. 100 tablets — — FDA listed —
Coated Aspirin 325 mg 50844-0254-12 L.N.K. 100 tablets — — FDA listed —
Aspirn 325 mg 51662-1583-01 HF 2 tablets — — FDA listed —
Aspirin 325 mg 53185-0249-12 Athlete's 100 tablets — — FDA listed —
Aspirin 325 mg 53943-0157-12 Discount 100 tablets — — FDA listed —
Geritrex Aspirin 325 mg 54162-0940-90 Geritrex 1000 tablets — — FDA listed —
Aspirin 325 mg 54738-0541-01 Richmond 100 tablets — — FDA listed —
Aspirin 325 mg 55301-0157-12 ARMY 100 tablets — — FDA listed —
Rapidol Aspirin 325 mg 55758-0363-60 Pharmadel 60 tablets — — FDA listed —
Aspirin 325 mg 55910-0249-29 DOLGENCORP, 150 tablets — — FDA listed —
aspirin 325 mg 56062-0118-11 PUBLIX 100 tablets — — FDA listed —
Aspirin 325 mg 57243-0157-12 Salado 100 tablets — — FDA listed —
Aspirin 325 mg 57344-0018-11 AAA 100 tablets — — FDA listed —
Aspirin 325 mg 57896-0901-01 Geri-Care 100 tablets — — FDA listed —
Aspirin 325 mg 58228-0071-01 PROSTAT 20000 tablets — — FDA listed —
Travel Savvy Aspirin 325 mg 59961-0616-15 Bellegrove 2 tablets — — FDA listed —
Aspirin 325 mg 60760-0930-24 St. 24 tablets — — Discontinued —
Direct Safety Aspirin 325 mg 61245-0616-13 Direct 2 tablets — — FDA listed —
Aspirin 325 mg 63941-0118-19 VALU 300 tablets — — FDA listed —
Aspirin NSAID 325 mg 63941-0157-12 Valu 100 tablets — — FDA listed —
Aspirin 325 mg 63941-0249-12 Valu 100 tablets — — Discontinued —
Circle K Aspirin 325 325 mg 66715-5504-04 Lil 100 tablets — — FDA listed —
BAYER Aspirin Original, TRAVEL BASIX 325 mg 66715-6426-02 Lil' 4 tablets — — FDA listed —
BAYER Aspirin Original, CVP HEALTH 325 mg 66715-6526-02 Lil' 4 tablets — — FDA listed —
Lil Drug Store Aspirin 325 325 mg 66715-6840-06 Lil 100 tablets — — FDA listed —
Bayer 325 mg 66715-9726-02 Lil' 4 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 67751-0129-01 Navajo 2 tablets — — FDA listed —
Aspirin 325 mg 68788-8256-01 Preferred 100 tablets — — FDA listed —
Aspirin 325 mg 68998-0018-11 Marc 100 tablets — — FDA listed —
Aspirin 325 mg 69168-0312-01 Allegiant 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0158-01 Trifecta 100 tablets — — FDA listed —
Aspirin 325 mg 69396-0173-01 Trifecta 1000 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 69517-0002-05 HealthLife 500 tablets — — Discontinued —
Aspirin 325 mg 69732-0008-01 Hi-Tech 200 tablets — — FDA listed —
ULINE Aspirin 325 mg 69790-0616-33 ULINE 2 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 70264-0013-01 R 100 tablets — — FDA listed —
Aspirin Packs 325 mg 70385-2006-02 Sina 2 tablets — — FDA listed —
Tri-Buffered Aspirin 325 mgthis 71205-0517-90 Proficient 90 tablets — — FDA listed —
Aspirin 325 mg 71679-0302-00 Health 28500 tablets — — FDA listed —
Aspirin 325 mg 72036-0018-11 HARRIS 100 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 72476-0018-11 RETAIL 100 tablets — — FDA listed —
Aspirin 325 mg 72789-0574-25 PD-Rx 25 tablets — — FDA listed —
Aspirin Regular Strength 325 mg 73057-0365-08 Ulai 100 tablets — — FDA listed —
Thompson Aspirin 325 mg 73408-0618-33 Thompson 2 tablets — — FDA listed —
Aspirin 50 CT 325 mg 73598-1112-01 JHK 50 tablets — — FDA listed —
Aspirin 325 mg 77333-0050-20 Gendose 1 tablet — — FDA listed —
Aspirin 325 mg 79481-1570-01 Meijer 100 tablets — — FDA listed —
Aspirin 325 mg 82804-0167-60 Proficient 60 tablets — — FDA listed —
Aspirin 325 mg 82804-0237-04 Proficient 4 tablets — — FDA listed —
Extra Strength Aspirin 325 mg 83586-0115-01 HHH 100 tablets — — FDA listed —
Aspirin 325 mg 85111-0901-10 RMT 1000 tablets — — FDA listed —
Bayer Genuine Aspirin 325 mg 85237-1828-01 Select 1 tablet — — FDA listed —
Medique at Home Aspirin 325 mg 85766-0125-01 Sportpharm 2 tablets — — FDA listed —
Aspirin 325 mg 17714-0011-01 Advance 100 tablets — — FDA listed —
Aspirin 325 mg 54738-0111-01 Richmond 100 tablets — — FDA listed —
Aspirin 325 mg 71610-0034-65 Aphena 100 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 57896-0921-01 Geri-Care 100 tablets — — FDA listed —
Drug Mart Effervescent Pain Relief 325 mg 53943-0431-36 Discount 2 tablets — — FDA listed —
Dollar General Effervescent Pain Reliever 325 mg 55910-0040-36 Dolgencorp, 2 tablets — — FDA listed —
Publix Fast Relief Effervescent - Original Flavor 325 mg 56062-0358-36 PUBLIX 2 tablets — — FDA listed —
Best Choice Effervescent Pain Reliever 36 325 mg 63941-0241-12 VALU 2 tablets — — FDA listed —
Aspirin 325 mg 85111-0921-10 RMT 1000 tablets — — FDA listed —
HEB Effervescent Pain Relief 325 mg 37808-0861-36 H. 2 tablets — — FDA listed —
Signature Select Effervescent Pain Relief 325 mg 21130-0295-36 Safeway 2 tablets — — FDA listed —
TopCare Effervescent Pain Relief 325 mg 36800-0789-36 TOPCO 2 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 60760-0799-24 St. 24 tablets — — Discontinued —
Aspirin 325 mg 80425-0293-01 Advanced 30 tablets — — FDA listed —
Aspirin 325 Mg Ec 71335-1800-01 Bryant 30 tablets — — FDA listed —
Aspirin 325 mg 72789-0556-07 PD-Rx 7 tablets — — FDA listed —
Aspirin 325 mg 84269-2501-01 Wildman 2 tablets — — FDA listed —
Winco Foods Effervescent Pain Relief 325 mg 67091-0448-36 Winco 2 tablets — — FDA listed —
Family Wellness Pain Reliever 325 mg 55319-0870-36 FAMILY 2 tablets — — FDA listed —
Bayer Aspirin Regimen enteric coated 325 mg 00280-2110-10 Bayer 100 tablets — — FDA listed —
Aspirin 325 mg 67091-0110-10 WinCo 100 tablets — — Discontinued —
Aspirin 325 Mg Ec 69618-0015-01 Reliable 100 tablets — — FDA listed —
Aspirin 325 Mg Ec 71205-0318-20 Proficient 20 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 17856-0922-01 ATLANTIC 1 tablet — — FDA listed —
Aspirin 325 mg 37808-0174-32 H-E-B 300 tablets — — FDA listed —
CVS Effervescent Pain Reliever 325 mg 51316-0359-36 CVS 2 tablets — — FDA listed —
Aspirin 325 mg 59779-0157-14 CVS 500 tablets — — FDA listed —
Meijer Effervescent Pain Relief 325 mg 79481-0073-06 Meijer 2 tablets — — FDA listed —
Quality Choice Effervescent Pain Relief 325 mg 83324-0018-36 CHAIN 2 tablets — — FDA listed —
Aspirin 325 mg 51662-1494-01 HF 100 tablets — — FDA listed —
Aspirin 325 mg 00363-6453-53 WALGREENS 500 tablets — — FDA listed —
Aspirin 325 mg 81522-0018-11 FSA 100 tablets — — FDA listed —
Equaline Effervescent Pain Reliever 325 mg 41163-0741-36 UNITED 2 tablets — — FDA listed —
Good Sense Effervescent Pain Relief 325 mg 50804-0422-36 Perrigo 2 tablets — — FDA listed —
Regular Strength Enteric coated aspirin 325 mg 71335-0513-01 Bryant 30 tablets — — FDA listed —
Market Basket Effervescent Pain Relief 325 mg 53942-0883-36 DEMOULAS 2 tablets — — FDA listed —
Ecotrin Regular Strength 325 mg 63029-0302-01 Medtech 300 tablets — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

Availability & generic status

🏛️
1990
On the market since
Mar 1990
📍
2026
Currently FDA-listed
36 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

What it looks like

Color White
ShapeRound
Imprint44;183
Size11 mm
ScoringNot scored
One label can cover several strengths, so colors may be combined — always confirm a loose pill against the dispensed prescription label or a pharmacist.
Where does this data come from?
Physical description (imprint, shape, color, scoring, coating) from this product’s FDA Structured Product Labeling (SPL), mirrored from DailyMed / openFDA.

Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

Manufacturer & labeler

LabelerProficient Rx LP
FDA applicationM013 (OTC MONOGRAPH DRUG)
Labeler code71205
First marketedMar 1990
Product typeHuman Otc Drug
Portfolio1,729 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose 📄 Do Not Use 📄 Ask a Doctor Before Use If 📄 Ask a Doctor or Pharmacist Before Use If 📄 Stop Use and Ask a Doctor If 🤰 If Pregnant or Breast-Feeding 📄 Keep Out of Reach of Children 📄 Questions or Comments 📄 Package Label / Principal Display Panel
🎯 Indications and Usage 37 words ▾

Uses • temporarily relieves minor aches and pains associated with: o toothache o minor pain of arthritis o backache o the common cold o headache o muscular aches o premenstrual & menstrual cramps • temporarily reduces fever

⏱️ Dosage and Administration 51 words ▾

Directions • drink a full glass of water with each dose • adults and children 12 years and over: take 2 tablets every 4 hours not to exceed 12 tablets in 24 hours unless directed by a doctor • children under 12 years: do not use unless directed by a doctor

⚠️ Warnings ~2 min read ▾

Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Aspirin may cause a severe allergic reaction, which may include: • hives • facial swelling • shock • asthma (wheezing) Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if you • have had stomach ulcers or bleeding problems • have 3 or more alcoholic drinks every day while using this product • are age 60 or older • take a blood thinning (anticoagulant) or steroid drug • take other drugs containing prescription or nonprescription NSAIDs [aspirin, ibuprofen, naproxen, or others] • take more or for a longer time than directed Do not use • if you are allergic to aspirin or any other pain reliever/fever reducer • if you have ever had an allergic reaction to this product or any of its ingredients Ask a doctor before use if • stomach bleeding warning applies to you • you have a history of stomach problems, such as heartburn • you have asthma • you are taking a diuretic • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease Ask a doctor or pharmacist before use if you are taking a prescription drug for • gout • arthritis • diabetes Stop use and ask a doctor if • an allergic reaction occurs.

Seek medical help right away. • you experience any of the following signs of stomach bleeding: o feel faint o vomit blood o have bloody or black stools o have stomach pain that does not get better • ringing in the ears or a loss of hearing occurs • pain gets worse or lasts more than 10 days • fever gets worse or lasts more than 3 days • redness or swelling is present • new symptoms occur These could be signs of a serious condition. If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📦 Storage and Handling 33 words ▾

Other information • each tablet contains: calcium 35 mg and magnesium 40 mg • store at 25ºC (77ºF); excursions permitted between 15º-30ºC (59º-86ºF) • see end flap for expiration date and lot number

🧪 Active Ingredient 25 words ▾

Active ingredient (in each tablet) Buffered aspirin equal to 325 mg aspirin (NSAID)* (buffered with calcium carbonate, magnesium carbonate, and magnesium oxide) *nonsteroidal anti-inflammatory drug

🧪 Inactive Ingredients 30 words ▾

Inactive ingredients anhydrous citric acid, corn starch, dibasic sodium phosphate anhydrous, hydrogenated vegetable oil, hypromellose, microcrystalline cellulose, polyethylene glycol, propylene glycol, shellac wax, simethicone, sodium lauryl sulfate, talc, titanium dioxide

🎯 Purpose 4 words ▾

Purpose Pain reliever/fever reducer

📄 Do Not Use 33 words ▾

Do not use • if you are allergic to aspirin or any other pain reliever/fever reducer • if you have ever had an allergic reaction to this product or any of its ingredients

📄 Ask a Doctor Before Use If 47 words ▾

Ask a doctor before use if • stomach bleeding warning applies to you • you have a history of stomach problems, such as heartburn • you have asthma • you are taking a diuretic • you have high blood pressure, heart disease, liver cirrhosis, or kidney disease

📄 Ask a Doctor or Pharmacist Before Use If 21 words ▾

Ask a doctor or pharmacist before use if you are taking a prescription drug for • gout • arthritis • diabetes

📄 Stop Use and Ask a Doctor If 98 words ▾

Stop use and ask a doctor if • an allergic reaction occurs. Seek medical help right away. • you experience any of the following signs of stomach bleeding: o feel faint o vomit blood o have bloody or black stools o have stomach pain that does not get better • ringing in the ears or a loss of hearing occurs • pain gets worse or lasts more than 10 days • fever gets worse or lasts more than 3 days • redness or swelling is present • new symptoms occur These could be signs of a serious condition.

🤰 If Pregnant or Breast-Feeding 47 words ▾

If pregnant or breast-feeding, ask a health professional before use. It is especially important not to use aspirin during the last 3 months of pregnancy unless definitely directed to do so by a doctor because it may cause problems in the unborn child or complications during delivery.

📄 Keep Out of Reach of Children 22 words ▾

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away.

📄 Questions or Comments 5 words ▾

Questions or comments? (800) 616-2471

📄 Package Label / Principal Display Panel 93 words ▾

Principal Display Panel NDC 71205-517-30 Compare to the active ingredient in BUFFERIN ®† TRI-BUFFERED ASPIRIN 325 mg pain reliever/fever reducer (NSAID) 30 TABLETS † This product is not manufactured or distributed by Dr. Reddy's Laboratories Inc., owner of the registered trademark Bufferin ® . 50844 REV0318M18312 Distributed by MAJOR ® PHARMACEUTICALS 17177 N Laurel Park Drive, Suite 233 Livonia, MI 48152 USA Repackaged by Proficient Rx LP Thousand Oaks, CA 91320 M-17 Re-order No.

700594 Rev. 07/18 TAMPER EVIDENT: DO NOT USE IF IMPRINTED SAFETY SEAL UNDER CAP IS BROKEN OR MISSING 71205-517-30

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗

Reported adverse events (FAERS)

Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Aspirin — the ingredient across all brands.

Top reported reactions

Fatigue34,118
Nausea28,880
Dyspnoea28,759
Diarrhoea28,193
Dizziness24,025
Headache21,817
Asthenia19,874

Reporter sex

560,732 reports
Male · 50%
Female · 50%
Unknown · 0%

Serious outcomes

Hospitalization212,381
Death49,779
Life-threatening25,790
Disabling16,209
Reports over time (by year) — tap or hover for the count & year
2019 2021 2023 2026 35,973 0
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.

About this NDC listing & data coverage

Over-the-counter (OTC) product
What data is (and isn’t) available for this NDC — tap to expand
NDC identity (package / product / labeler codes) ✓ Available
Labeler ✓ Available
Product & package description ✓ Available
Marketing category & status ✓ Available
Active ingredient / dosage form / route ✓ Available
FDA label (SPL via DailyMed) ✓ Available
Package photos — Not published for this NDC No photo available yet for this listing.
Inactive ingredients (structured) — Not published for this NDC The labeler did not submit a structured excipient list, or no SPL is available.
NADAC pharmacy acquisition price (CMS) — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey.
Orange Book / therapeutic-equivalence data — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope.
HCPCS J-code billing crosswalk — Not published for this NDC Most self-administered / retail products have no J-code — that is normal.
Medicaid utilization (CMS SDUD) — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold.
“Not published” reflects what the public FDA / CMS / NLM sources provide for this exact package code — it is a property of the data feeds, not a judgment about the product.

Questions about this listing

Is this NDC FDA-approved?
An NDC listing does not by itself establish FDA approval — the NDC Directory records that a product is listed with FDA, not that it was reviewed and approved. This listing's marketing category is "Otc Monograph Drug". Products approved under an application carry an NDA, ANDA, or BLA number.
Why is there no price listed?
The pricing shown on our NDC pages comes from CMS NADAC, a voluntary survey of retail community pharmacy invoices. CMS does not publish a NADAC for every NDC — packages outside the retail survey (institutional and hospital products, bulk packages, discontinued items, and many OTC items) may never receive one. A missing price reflects the survey's scope, not this product's actual cost, and does not mean the product is free or unavailable.
Is the NDC printed on the package the same as the 11-digit billing NDC?
Yes, they identify this exact package in different formats. The form printed on the packaging and shown on DailyMed is the one the FDA registered. Insurance claims use a fixed 11-digit 5-4-2 format, so the short segment is padded with a leading zero and the dashes are dropped. The Identity section at the top of this page lists each form of this code.
Is this package still being marketed?
Yes, per the latest FDA NDC Directory data on this page: this package is listed as actively marketed, with no marketing end date reported by Proficient Rx LP. Listing status can change — the directory data on this page refreshes weekly.
Does this product come in other package sizes?
Yes — the FDA directory lists 2 other package presentations of this same product, including 30 tablets (71205-0517-30), 60 tablets (71205-0517-60). Each has its own NDC and its own page — see the package list near the top of this page.
Who lists this product with the FDA?
Proficient Rx LP is the labeler of record for this NDC — the company under whose FDA-assigned code the package is listed. The labeler may be the manufacturer itself or a distributor marketing the product under its own code.
Do I need a prescription for this product?
This NDC is listed with FDA as an over-the-counter product, so it does not require a prescription. Follow the package directions, and ask your pharmacist if you are unsure whether it is right for you.
This page identifies an FDA-listed package (the NDC) and reports public regulatory and pricing data about the listing. It is reference information, not a medical recommendation — talk to your pharmacist or prescriber about your own medication.
Where does this data come from?
Listing facts (marketing category, packager status, marketing dates) from the FDA openFDA NDC Directory; label availability from DailyMed; pricing coverage from CMS NADAC; equivalence scope from the FDA Orange Book.
← 71205-0516-30 · Proficient 71205-0518-02 · Proficient →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.