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QUALITY CHOICE Phenylephrine Hydrochloride 1 g/100mL Solution/ Drops — NDC 83324-0215-01 package photo

QUALITY CHOICE Phenylephrine Hydrochloride 1 g/100mL Solution/ Drops

by CHAIN DRUG MARKETING ASSOCIATION · 1 BOTTLE, DROPPER in 1 CARTON (83324-215-01) / 30 mL in 1 BOTTLE, DROPPER
NDC 83324-0215-01
🏷️ FDA NDC (as labeled) 83324-215-01 billing pads the product segment with a zero
OTC On market Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →

This page is curated, coded, and maintained by

Compiled from public FDA, CMS, DailyMed, NADAC, and related drug data sources. Editorial policy

🆔 Identity & classification

FDA NDC (as labeled) 83324-215-01
Product NDC 83324-215
11-digit billing NDC 83324021501
UNII 04JA59TNSJ
UPC 0635515992825
Application # M012
SPL Set ID 14596551-dd82-46b3-8eb8-e69efaea105b
Established class (EPC) alpha-1 Adrenergic Agonist
Mechanism of action Adrenergic alpha1-Agonists
DEA schedule Non-controlled
Marketing category OTC MONOGRAPH DRUG
Marketing status On market
FDA listing status Listed (active directory)
Marketing start 2024-10-08
Route NASAL
Dosage form SOLUTION/ DROPS
Substance PHENYLEPHRINE HYDROCHLORIDE
GCN Seq No 008062
GCN 34124
HICL code 002087
Ingredient (HICL) Phenylephrine Hcl
HIC1 code Q
Therapeutic class — broad (HIC1) Ear/Eye/Nose/Rectum/Topical/Vagina/Other
HIC2 code Q7
Therapeutic class — intermediate (HIC2) Nasal Preparations
HIC3 code Q7D
Therapeutic class — specific (HIC3) Nose Preparations, Vasoconstrictors(Otc)
AHFS code 12:12.04.00
AHFS class Alpha-Adrenergic Agonists (12:12)
FDB label name QC NASAL SPRAY 1%
FDB brand name Nasal Spray
Legend status O — Over-the-counter (OTC) drug or device
Why two NDCs? The FDA registers this code as 83324-215-01 — a 5-3-2 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the product segment → 83324-0215-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.

🏭 Manufacturer & labeler

LabelerCHAIN DRUG MARKETING ASSOCIATION
FDA applicationM012 (OTC MONOGRAPH DRUG)
Labeler code83324
First marketedOct 2024
Product typeHuman Otc Drug
Portfolio128 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.

🩺 Clinical

Label name QC NASAL SPRAY 1% Ingredient Phenylephrine Hcl
📖 What it is MedlinePlus · NLM

Phenylephrine nasal spray is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine nasal spray will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Phenylephrine is in a class of medications called nasal decongestants. It works by reducing swelling of the blood vessels in the nasal passages.

Read the full MedlinePlus article ↗
📗 Our plain-language guide HelloPharmacist
  • Yes, it's the same active ingredient, but used in very different ways depending on the form. The nasal spray delivers a tiny amount directly to the nasal lining to temporarily shri...
  • I see phenylephrine in nasal sprays at the pharmacy AND as an IV drug in the hospital — is it really the same medication?
  • You should check with your doctor first. Phenylephrine constricts blood vessels, which can raise blood pressure and put extra strain on the heart — even from a nasal spray. If you...
  • Can I use the nasal spray if I have high blood pressure or heart disease?
📖 Read our full Phenylephrine guide →

Supplement & herbal interactions

Some supplements/herbs that may interact with Phenylephrine Hydrochloride — tap one for details:

Butcher's BroomModerate
🌿 Every supplement checked against Phenylephrine Hydrochloride (1 interactions) — ranked by severity →
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.

🧪 Inactive Ingredients / Excipients

Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.

Loading inactive ingredients from the official FDA label in the background. No external source is being called by this page request.
Where does this data come from?
Source: official FDA Structured Product Labeling (SPL) via DailyMed and the openFDA label index. Structured IACT rows and label-wide narrative are kept separate; availability and product-level specificity depend on the submitted label.

Inactive ingredient FAQ

Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.

💲 Pricing

A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.

Price systemPer mLPer package
Retail pharmacies payNADAC · weekly $0.070 $2.11 / 30 ml
Medicaid paysCMS SDUD · 12 mo No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data.
Medicare drug plans payPart D · quarterly No Part D plan price is available for this NDC in our data.
NADAC price history (per mL) — tap or hover for the price & month
Dec 2025 Mar 2026 Jun 2026 Sep 2026 $0.070 $0.068
▲ Up 3% over the last 10 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.

🔁 Therapeutic equivalents

ProductLabelerPackNADAC/unitTEStatusPrice vs. this
Good Sense Nasal Four 1 g/100mL 00113-0648-10 L. 1 bottle $0.067 — Availability likely save 4%
Extra Strength Sinus Relief Nasal Decongestant 1 g/100mL 70000-0132-01 CARDINAL 1 bottle $0.070 — Availability likely —
Quality Choice 1 g/100mLthis 83324-0215-01 CHAIN 1 bottle $0.070 — Availability likely —
good neighbor pharmacy nasal four 1 g/100mL 46122-0689-03 Amerisource 1 bottle $0.084 — Availability likely +20%
4 Way Fast Acting 10 mg/mL 00067-2086-01 Haleon 1 bottle — — FDA listed —
Neo-Synephrine Maximum 1 g/100mL 00225-0810-47 BF 15 ml — — FDA listed —
Neo-Synephrine Severe 1 g/100mL 00225-0811-47 BF 15 ml — — FDA listed —
nasal 1 g/100mL 00363-0717-10 Walgreen 1 bottle — — FDA listed —
Better Living 1 g/100mL 21130-0728-30 BETTER 1 bottle — — FDA listed —
nasal 1 g/100mL 30142-0539-10 Kroger 1 bottle — — FDA listed —
Topcare Nasal Four 1 g/100mL 36800-0648-10 Topco 1 bottle — — FDA listed —
heb nasal 1 g/100mL 37808-0728-30 H 1 bottle — — FDA listed —
equaline nasal 1 g/100mL 41163-0648-10 United 1 bottle — — FDA listed —
Publix 1 g/100mL 41415-0728-30 PUBLIX 1 bottle — — FDA listed —
CareOne Fast Acting Nasal 1 g/100mL 41520-0729-10 American 1 bottle — — FDA listed —
Nasal Four 1 g/100mL 42507-0648-10 HyVee 1 bottle — — FDA listed —
Equate Nasal 1 g/100mL 49035-0648-10 Wal-Mart 1 bottle — — FDA listed —
No Drip Nasal 10 mg/mL 51316-0648-10 CVS 1 bottle — — FDA listed —
dg health nasal four 1 g/100mL 55910-0802-10 Dolgencorp, 1 bottle — — FDA listed —
Dollar General 1 g/100mL 55910-0827-30 DOLGENCORP, 1 bottle — — FDA listed —
CVS Health Four Actions Nasal Decongestant 10 mg/mL 59779-0838-30 CVS 1 bottle — — FDA listed —
Quality Choice 1 g/100mL 63868-0697-30 CHAIN 1 bottle — — FDA listed —
Extra Strength Nasal 1 g/100mL 69842-0443-30 CVS 1 bottle — — FDA listed —
Nasal 1 g/100mL 69842-0648-10 CVS 1 bottle — — FDA listed —
basic care nasal 1 g/100mL 72288-0648-10 Amazon.com 1 bottle — — FDA listed —
Nasal 1 g/100mL 79481-0101-00 Meijer, 1 bottle — — FDA listed —
Equate Nasal 10 mg/mL 79903-0276-01 WALMART 1 bottle — — FDA listed —
Ephrine Nose Drops 1 g/100mL 00363-2023-10 Walgreens 1 bottle — — FDA listed —
Nasal 1 g/100mL 72288-0742-10 Amazon.com 1 bottle — — FDA listed —
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.

⏳ Availability & generic status

🏛️
2024
On the market since
Oct 2024
📍
2026
Currently FDA-listed
2 years listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found

We did not find an FDA-approved generic match for this exact strength, form and route.

Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.

📦 Packaging — all sizes for this product

Package NDCDescription Marketing startStatus
83324-0215-01 You're viewing this 1 BOTTLE, DROPPER in 1 CARTON (83324-215-01) / 30 mL in 1 BOTTLE, DROPPER 2024-10-08 Active

📄 FDA label — Drug Facts FDA SPL

The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage ⏱️ Dosage and Administration ⚠️ Warnings 📦 Storage and Handling 🧪 Active Ingredient 🧪 Inactive Ingredients 🎯 Purpose
🎯 Indications and Usage 16 words ▾

Uses for the temporarily relief nasal congestion due to: common cold hay fever upper respiratory allergies

⏱️ Dosage and Administration 60 words ▾

Directions adults and children 12 years of age and over: 2 or 3 sprays in each nostril not more than every 4 hours children under 12 years of age: ask a doctor Use instructions: with head in a normal, upright position, put atomizer tip into nostril. Squeeze bottle with firm, quick pressure while inhaling. Wipe nozzle clean after each use.

⚠️ Warnings 126 words ▾

Warnings Ask a doctor before use if you have heart disease high blood pressure thyroid disease diabetes trouble urinating due to an enlarged prostate gland When using this product do not use more than directed do not use for more than 3 days. Use only as directed. Frequent or prolonged use may cause nasal congestion to recur or worsen. temporary discomfort such as burning, stinging, sneezing, or an increase in nasal discharge may occur infection may spread if this container is used by more than one person Stop use and ask a doctor if symptoms persist If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away (1-800-222-1222).

📦 Storage and Handling 6 words ▾

Other information store at room temperature

🧪 Active Ingredient 5 words ▾

Active ingredient Phenylephrine hydrochloride 1%

🧪 Inactive Ingredients 14 words ▾

Inactive ingredients benzalkonium chloride, benzyl alcohol, citric acid, purified water, sodium chloride, sodium citrate

🎯 Purpose 3 words ▾

Purpose Nasal decongestant

Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA. Prefer the government’s original formatting? View this label on DailyMed ↗
← 83324-0211-01 · CHAIN 83324-0217-04 · QUALITY →
For educational and professional reference only — not medical advice. Pricing reflects published NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.