Drug & supplement interaction

7-beta-hydroxy-dhea + Doxylamine Succinate, Pyridoxine Hydrochloride

Doxylamine Succinate, Pyridoxine Hydrochloride brand names: Diclegis, Bonjesta.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Doxylamine Succinate, Pyridoxine Hydrochloride states a food rule worth keeping to.

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Interaction report

7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Doxylamine Succinate, Pyridoxine Hydrochloride and 7-beta-hydroxy-dhea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 7-beta-hydroxy-dhea at all — not against Doxylamine Succinate, Pyridoxine Hydrochloride, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

7-beta-hydroxy-dhea safety at a glance

7-beta-hydroxy-dhe... overall Not established Human safety data are very limited, so use with caution.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Doxylamine Succinate, Pyridoxine Hydrochloride and 7-beta-hydroxy-dhea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Doxylamine Succinate, Pyridoxine Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves 7-beta-hydroxy-dhea. These are the most notable effects listed in the ADVERSE REACTIONS section of Doxylamine Succinate, Pyridoxine Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 6 of them are worth acting on rather than waiting out — marked below.

  • Pain or burning when passing urine Worth acting on
  • Trouble passing urine Worth acting on
  • Confusion Worth acting on
  • Chest pain Worth acting on
  • Shortness of breath Worth acting on
  • An allergic reaction Worth acting on
  • Vivid dreams or nightmares
  • Migraine
  • Mood changes or irritability
  • Bloating or gas

Showing the 10 most notable of 27 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Doxylamine Succinate, Pyridoxine Hydrochloride. Read the label on DailyMed › 7-beta-hydroxy-dhea’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no 7-beta-hydroxy-dhea side to compare — that is a limit of the record, not a statement that 7-beta-hydroxy-dhea has no side effects.

Special populations

7-beta-hydroxy-dhea in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

How to take them

Some Doxylamine Succinate, Pyridoxine Hydrochloride Products Have a Food Rule — 7-beta-hydroxy-dhea Should Not Break It

At least one FDA label for a product containing Doxylamine Succinate, Pyridoxine Hydrochloride says to take it on an empty stomach. Most supplements — 7-beta-hydroxy-dhea included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Doxylamine Succinate, Pyridoxine Hydrochloride on its own and move 7-beta-hydroxy-dhea to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Doxylamine Succinate, Pyridoxine Hydrochloride products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Take on an empty stomach with a glass of water [ see Clinical Pharmacology (12.3) ].

From the Dosage and Administration section of the FDA label we read for Doxylamine Succinate, Pyridoxine Hydrochloride — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Doxylamine Succinate, Pyridoxine Hydrochloride

This page covers 7-beta-hydroxy-dhea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Doxylamine Succinate, Pyridoxine Hydrochloride page lists 46 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Henbane (major), Scopolia (major), Angel's Trumpet (moderate) and Bacopa (moderate).

By severity: 3 major · 32 moderate · 11 minor.

From our pharmacist’s overview on the Doxylamine Succinate, Pyridoxine Hydrochloride page

“If you take doxylamine and pyridoxine (Diclegis, Bonjesta) for pregnancy nausea, this list deserves genuine care, because three of its 46 entries carry a major rating. The risk splits two ways.”

Reviewed by 2 · Jul 18, 2026

Open the Doxylamine Succinate, Pyridoxine Hydrochloride interaction page

One more smart check

Taking 7-beta-hydroxy-dhea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing 7-beta-hydroxy-dhea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 7-beta-hydroxy-dhea. Even though 7-beta-hydroxy-dhea itself has no known interaction with Doxylamine Succinate, Pyridoxine Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 7-beta-hydroxy-dhea
Steady interest

#771 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Doxylamine Succinate, Pyridoxine Hydrochloride
Steady interest

#2,702 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 7-beta-hydroxy-dhea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 7-beta-hydroxy-dhea

What is 7-beta-hydroxy-dhea?

  • Weight management
  • Immune support
  • Anti-aging
  • Memory and cognition
  • General hormone support

7-beta-hydroxy-DHEA is a natural breakdown product (metabolite) of the hormone DHEA, and it is sometimes sold as a supplement marketed for weight loss, immune support, and anti-aging. There is very little solid human research to support these uses, and its long-term safety is not well understood, so caution is warranted. Talk with your pharmacist or doctor before trying it.

Not a plant product; a metabolite of DHEA produced in the body or made synthetically · Capsules, tablets

An interaction check asks whether these two react with each other — it does not ask whether 7-beta-hydroxy-dhea is a good idea for someone in your situation. Here is what our 7-beta-hydroxy-dhea record says about it on its own.

7-beta-hydroxy-dhea: dosing

There is no established, well-studied dose for 7-beta-hydroxy-DHEA. Because reliable human studies are lacking, no one can confidently recommend a safe and effective amount.If you choose to use a product despite the limited evidence, follow the directions on the label and do not exceed them. Choosing products that have been independently tested for quality can help reduce the risk of contamination or inaccurate labeling.

From our 7-beta-hydroxy-dhea monograph — the full record covers uses, side effects and every documented interaction.

Read the full 7-beta-hydroxy-dhea monograph & all interactions
Medication

About Doxylamine and Pyridoxine

What Is Doxylamine and Pyridoxine Used For?

Brand names: Diclegis, Bonjesta

Doxylamine and pyridoxine is indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management. This applies to the delayed-release tablets (including Diclegis and the generic doxylamine succinate and pyridoxine hydrochloride delayed-release tablets) as well as to Bonjesta, the extended-release tablet formulation.

None of these products have been studied in women with hyperemesis gravidarum (severe, persistent vomiting in pregnancy), so their use in that setting is not established.

See full Doxylamine and Pyridoxine drug information
Keep checking

Other Drugs & 7-beta-hydroxy-dhea

Browse every other medication we’ve checked against 7-beta-hydroxy-dhea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

7-beta-hydroxy-dhea References

The 1 references that drive our 7-beta-hydroxy-dhea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride Together: Common Questions

Is it safe to take 7-beta-hydroxy-dhea with Doxylamine Succinate, Pyridoxine Hydrochloride?
We do not list a known interaction between 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take 7-beta-hydroxy-dhea and Doxylamine Succinate, Pyridoxine Hydrochloride at the same time of day?
At least one FDA label for a product containing Doxylamine Succinate, Pyridoxine Hydrochloride says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Doxylamine Succinate, Pyridoxine Hydrochloride on its own and move 7-beta-hydroxy-dhea to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
Does Doxylamine Succinate, Pyridoxine Hydrochloride interact with any supplements?
Yes. Doxylamine Succinate, Pyridoxine Hydrochloride has documented interactions with 46 supplements in our database — 7-beta-hydroxy-dhea is not one of them. The Doxylamine Succinate, Pyridoxine Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Doxylamine Succinate, Pyridoxine Hydrochloride and 7-beta-hydroxy-dhea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.