Drug & supplement interaction

7-beta-hydroxy-dhea + Abemaciclib

Abemaciclib brand name: Verzenio.

No Known Interaction
The bottom line No known interaction

We found no known interaction between 7-beta-hydroxy-dhea and Abemaciclib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

7-beta-hydroxy-dhea and Abemaciclib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Abemaciclib and 7-beta-hydroxy-dhea in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for 7-beta-hydroxy-dhea at all — not against Abemaciclib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

7-beta-hydroxy-dhea safety at a glance

7-beta-hydroxy-dhe... overall Not established Human safety data are very limited, so use with caution.
Pregnancy Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced ferti... Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Abemaciclib and 7-beta-hydroxy-dhea? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Abemaciclib’s Own FDA Label Lists

This is not an interaction — none of it involves 7-beta-hydroxy-dhea. These are the most notable effects listed in the ADVERSE REACTIONS section of Abemaciclib’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • A stroke or mini-stroke Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Heart failure Worth acting on
  • A low platelet count Worth acting on
  • Anemia Worth acting on
  • A low white blood cell count Worth acting on
  • Liver problems Worth acting on
  • Bleeding or bruising Worth acting on
  • A higher chance of infection Worth acting on

Showing the 10 most notable of 21 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Abemaciclib. Read the label on DailyMed › Where a percentage is shown, it is the share of 19,870 voluntary FDA FAERS reports for Abemaciclib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. 7-beta-hydroxy-dhea’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no 7-beta-hydroxy-dhea side to compare — that is a limit of the record, not a statement that 7-beta-hydroxy-dhea has no side effects.

Special populations

7-beta-hydroxy-dhea in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally or parenterally. Anabolic androgenic steroids can disrupt the body's hormonal balance and cause various adverse effects including reduced fertility, hair loss, acne, and behavioral changes. Anabolic androgenic steroid use has also been associated with hepatotoxicity and increased risk for heart disease. The U.S. Food and Drug Administration and other regulatory agencies warn that dietary supplements containing anabolic steroids are dangerous. Avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Abemaciclib

This page covers 7-beta-hydroxy-dhea only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Abemaciclib page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Abemaciclib page

“A daily pill for a common form of advanced breast cancer, abemaciclib (Verzenio) only helps when its blood level stays steady, so this list of 138 supplements deserves genuine care. Nearly all of them act on CYP3A4, the liver enzyme that clears abemaciclib, meaning a supplement can push its level up and intensify side effects, or drag…”

Reviewed by 2 · Jul 18, 2026

Open the Abemaciclib interaction page

One more smart check

Taking 7-beta-hydroxy-dhea as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing 7-beta-hydroxy-dhea, each one broken down to its full ingredient list — and combination products often carry several ingredients besides 7-beta-hydroxy-dhea. Even though 7-beta-hydroxy-dhea itself has no known interaction with Abemaciclib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where 7-beta-hydroxy-dhea and Abemaciclib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement 7-beta-hydroxy-dhea
Steady interest

#940 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Abemaciclib
Top 10

#6 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every 7-beta-hydroxy-dhea reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The 7-beta-hydroxy-dhea and Abemaciclib records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About 7-beta-hydroxy-dhea

What is 7-beta-hydroxy-dhea?

  • Weight management
  • Immune support
  • Anti-aging
  • Memory and cognition
  • General hormone support

7-beta-hydroxy-DHEA is a natural breakdown product (metabolite) of the hormone DHEA, and it is sometimes sold as a supplement marketed for weight loss, immune support, and anti-aging. There is very little solid human research to support these uses, and its long-term safety is not well understood, so caution is warranted. Talk with your pharmacist or doctor before trying it.

Not a plant product; a metabolite of DHEA produced in the body or made synthetically · Capsules, tablets

An interaction check asks whether these two react with each other — it does not ask whether 7-beta-hydroxy-dhea is a good idea for someone in your situation. Here is what our 7-beta-hydroxy-dhea record says about it on its own.

7-beta-hydroxy-dhea: dosing

There is no established, well-studied dose for 7-beta-hydroxy-DHEA. Because reliable human studies are lacking, no one can confidently recommend a safe and effective amount.If you choose to use a product despite the limited evidence, follow the directions on the label and do not exceed them. Choosing products that have been independently tested for quality can help reduce the risk of contamination or inaccurate labeling.

From our 7-beta-hydroxy-dhea monograph — the full record covers uses, side effects and every documented interaction.

Read the full 7-beta-hydroxy-dhea monograph & all interactions
Medication

About Abemaciclib

What Is Abemaciclib Used For?

Brand name: Verzenio

Verzenio (abemaciclib) is used to treat adults with hormone receptor (HR)-positive, HER2-negative breast cancer. For early breast cancer at high risk of returning, Verzenio is taken alongside endocrine therapy (tamoxifen or an aromatase inhibitor) after surgery to help prevent recurrence.

For advanced or metastatic breast cancer, Verzenio can be used in three ways: combined with an aromatase inhibitor as a first hormonal treatment; combined with fulvestrant after the cancer has progressed on prior hormone therapy; or on its own after both hormone therapy and prior chemotherapy have stopped working.

Most-Reported Side Effects for Abemaciclib

From FAERS, the FDA’s public side-effect reporting system (19,870 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 6,094 reports
Fatigue 2,551 reports
Nausea 2,124 reports
Vomiting 1,119 reports
Malignant neoplasm progression 1,095 reports
See full Abemaciclib drug information
Keep checking

Other Drugs & 7-beta-hydroxy-dhea

Browse every other medication we’ve checked against 7-beta-hydroxy-dhea — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

7-beta-hydroxy-dhea References

The 1 references that drive our 7-beta-hydroxy-dhea monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking 7-beta-hydroxy-dhea and Abemaciclib Together: Common Questions

Is it safe to take 7-beta-hydroxy-dhea with Abemaciclib?
We do not list a known interaction between 7-beta-hydroxy-dhea and Abemaciclib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Abemaciclib interact with any supplements?
Yes. Abemaciclib has documented interactions with 138 supplements in our database — 7-beta-hydroxy-dhea is not one of them. The Abemaciclib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Abemaciclib and 7-beta-hydroxy-dhea?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.