American Dogwood - Unisom (Doxylamine Succinate) Interaction
Herbal: American Dogwood
Also Known As: Cornus florida, Bitter Redberry, Box Tree, Boxwood, Budwood, Cornejo Florido, Cornel, Cornelian Tree, Cornus, Dog-Tree, Dogwood, False Box, Flowering Dogwood, Green Ozier, Osier, Rose Willow, Silky Cornel, Swamp Dogwood
Drug: Doxylamine Succinate
Brand names:
Unisom
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 25, 2025
Interaction Details
There were no interactions found between Doxylamine Succinate and American Dogwood. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
American Dogwood Overview
Cornus florida, or flowering dogwood, is a deciduous tree native to eastern North America, known for its showy white or pink spring flowers. Its bark is rarely used in medicine. The tree grows 15-30 feet tall with a spreading crown and red berries in late summer, attracting birds. Its oval leaves turn vibrant red in autumn. Popular in landscaping for its beauty and adaptability, Cornus florida's bark may have antiparasitic effects, including antimalarial properties comparable to quinine and sulfadiazine. It also destroys snails carrying the tropical parasite Schistosoma. A methanol extract of its bark can inhibit heart activity, even stopping the heartbeat at high doses. The use of American dogwood in dietary supplements is uncommon.
Doxylamine Succinate Overview
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Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, and to treat insomnia (difficulty falling asleep or staying asleep). Diphenhydramine is also used to control abnormal movements in people who have early stage parkinsonian syndrome (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) or who are experiencing movement problems as a side effect of a medication.
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Diphenhydramine will relieve the symptoms of these conditions but will not treat the cause of the symptoms or speed recovery. Diphenhydramine should not be used to cause sleepiness in children. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
American Dogwood - More Interactions
American Dogwood interacts with 0 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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