Ascorbigen + Glecaprevir, Pibrentasvir
Glecaprevir, Pibrentasvir brand name: Mavyret.
We found no known interaction between Ascorbigen and Glecaprevir, Pibrentasvir in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Glecaprevir, Pibrentasvir states a food rule worth keeping to.
Ascorbigen and Glecaprevir, Pibrentasvir
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Glecaprevir, Pibrentasvir and Ascorbigen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Ascorbigen at all — not against Glecaprevir, Pibrentasvir, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Ascorbigen safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Glecaprevir, Pibrentasvir Products Have a Food Rule — Ascorbigen Should Not Break It
At least one FDA label for a product containing Glecaprevir, Pibrentasvir says to take it with food. If you take Ascorbigen on an empty stomach out of habit, keep them separate — and take Glecaprevir, Pibrentasvir with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Glecaprevir, Pibrentasvir products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
Recommended dosage in adults: Three tablets taken at the same time orally once daily (total daily dose: glecaprevir 300 mg and pibrentasvir 120 mg) with food.
From the Dosage and Administration section of the FDA label we read for Glecaprevir, Pibrentasvir — where that label names a specific product, the instruction is that product's. See the Glecaprevir, Pibrentasvir drug page ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Glecaprevir, Pibrentasvir
This page covers Ascorbigen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Glecaprevir, Pibrentasvir page lists 144 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 103 moderate · 38 minor.
From our pharmacist’s overview on the Glecaprevir, Pibrentasvir page
“Mavyret (glecaprevir and pibrentasvir) is a short course of pills meant to cure hepatitis C, so I read its supplement list with real caution. Nearly everything on it can shift how much of the drug reaches your blood, mostly through the CYP3A4 enzyme or the P-glycoprotein transporter that handles it.”
Reviewed by 2 · Jul 18, 2026
Taking Ascorbigen as Part of a Dietary Supplement Product? Check It for Interactions
We hold 2 real supplement products containing Ascorbigen, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ascorbigen. Even though Ascorbigen itself has no known interaction with Glecaprevir, Pibrentasvir, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Ascorbigen and Glecaprevir, Pibrentasvir Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,029 of 1,452 supplements looked up here in the last 7 days
#397 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ascorbigen reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Ascorbigen and Glecaprevir, Pibrentasvir records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Ascorbigen
What is Ascorbigen?
- Antioxidant support
- Immune support
- Fibromyalgia symptoms
- General wellness
- Detoxification support
Ascorbigen is a natural compound formed when indole-3-carbinol (from cruciferous vegetables) combines with vitamin C, and it is mainly studied in the lab and in early research. There is not enough good human evidence to confirm it helps any specific health condition, and its safety as a supplement is not well established. Talk with your pharmacist or doctor before taking it.
Derived from cruciferous vegetables (such as cabbage, broccoli, Brussels sprouts) · Capsules, tablets, found naturally in cruciferous vegetables and some combination supplements
An interaction check asks whether these two react with each other — it does not ask whether Ascorbigen is a good idea for someone in your situation. Here is what our Ascorbigen record says about it on its own.
Ascorbigen: dosing
There is no established standard dose for ascorbigen. It has not been studied enough in humans to know a safe and effective amount.If you choose to use a product that contains ascorbigen, follow the directions on the label and do not exceed the recommended amount.
From our Ascorbigen monograph — the full record covers uses, side effects and every documented interaction.
About Glecaprevir and Pibrentasvir
What Is Glecaprevir and Pibrentasvir Used For?
Brand name: Mavyret
Mavyret treats acute or chronic hepatitis C virus (HCV) infection caused by genotypes 1, 2, 3, 4, 5, or 6 in adults and children 3 years and older who have no cirrhosis or have compensated cirrhosis (mild liver scarring that is still functioning).
Mavyret is also approved for adults and children 3 years and older with genotype 1 HCV who were previously treated with either an NS5A inhibitor or an NS3/4A protease inhibitor (two earlier classes of hepatitis C drugs) — but not both at the same time.
Other Drugs & Ascorbigen
Browse every other medication we’ve checked against Ascorbigen — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Ascorbigen against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Amlodipine Besylate ›
- Methotrexate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Clonazepam ›
- Quetiapine ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Ascorbigen list.
Ascorbigen References
The 1 references that drive our Ascorbigen monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Ascorbigen and Glecaprevir, Pibrentasvir Together: Common Questions
Is it safe to take Ascorbigen with Glecaprevir, Pibrentasvir?
Should I take Ascorbigen and Glecaprevir, Pibrentasvir at the same time of day?
Does Glecaprevir, Pibrentasvir interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Glecaprevir, Pibrentasvir and Ascorbigen?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.