Drug & supplement interaction

Ascorbigen + Olaparib

Olaparib brand name: Lynparza.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Ascorbigen and Olaparib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Ascorbigen and Olaparib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Olaparib and Ascorbigen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ascorbigen at all — not against Olaparib, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ascorbigen safety at a glance

Ascorbigen overall Not established There is very little human safety data on ascorbigen as a supplement.
Pregnancy Avoid Safety has not been studied in pregnancy, so it is best to avoid it.
Breastfeeding Avoid No safety data exist for breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Olaparib and Ascorbigen? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Ascorbigen and Olaparib May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Bloating or gas Additional detail

    Ascorbigen

    “Orally, when used in combination with broccoli powder, ascorbigen has been reported to cause flatulence, abdominal distension, and unpleasant after taste. It is unclear if these effects are due to ascorbigen, broccoli powder, or the combination.”

    Ascorbigen · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 15460. Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.

    Olaparib

    Listed in the ADVERSE REACTIONS section of the FDA label for Olaparib. Read the label on DailyMed ›

Effects for Olaparib come from the ADVERSE REACTIONS section of its FDA label; effects for Ascorbigen come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 20,798 voluntary FDA FAERS reports for Olaparib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Olaparib Is Prescribed For, and What Ascorbigen Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Olaparib is a prescription medicine with approved uses on its FDA label. Ascorbigen is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Olaparib is prescribed for: Lynparza (olaparib) is used to treat adults with certain ovarian, fallopian tube, or primary peritoneal cancers that carry BRCA or other DNA-repair gene mutations — both as a maintenance therapy after platinum-based chemotherapy (including in combination with bevacizumab for some patients) and for recurrent disease. It is also approved for HER2-negative breast cancer with a germline BRCA mutation, both in early high-risk disease (adjuvant setting) and in metastatic disease. Lynparza is additionally used as maintenance therapy for adults with germline BRCA-mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on first-line platinum-based chemotherapy, and for adults with certain gene-mutated metastatic castration-resistant prostate cancer — either alone (after prior enzalutamide or abiraterone) or in combination with abiraterone and prednisone or prednisolone. All uses require testing for specific genetic mutations using an FDA-approved companion diagnostic before starting treatment.

Ascorbigen has been studied for:

  • Breast cancer studied, not established Ascorbigen has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Ascorbigen for breast cancer

    Although there has been interest in using oral ascorbigen for the prevention of breast cancer, there is insufficient reliable information about the clinical effects of ascorbigen for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Olaparib on your own; if you are taking Ascorbigen for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Olaparib

This page covers Ascorbigen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Olaparib page lists 138 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 94 moderate · 41 minor.

From our pharmacist’s overview on the Olaparib page

“Grapefruit is the first thing to drop if you take Olaparib (Lynparza). It blocks CYP3A4, the liver enzyme that clears this cancer drug, so levels can climb and side effects with them.”

Reviewed by 2 · Jul 18, 2026

Open the Olaparib interaction page

One more smart check

Taking Ascorbigen as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Ascorbigen, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ascorbigen. Even though Ascorbigen itself has no known interaction with Olaparib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Ascorbigen and Olaparib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ascorbigen
Steady interest

#1,097 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Olaparib
Steady interest

#1,886 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ascorbigen reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Ascorbigen and Olaparib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ascorbigen

What is Ascorbigen?

Ascorbigen
  • Antioxidant support
  • Immune support
  • Fibromyalgia symptoms
  • General wellness
  • Detoxification support

Ascorbigen is a natural compound formed when indole-3-carbinol (from cruciferous vegetables) combines with vitamin C, and it is mainly studied in the lab and in early research. There is not enough good human evidence to confirm it helps any specific health condition, and its safety as a supplement is not well established. Talk with your pharmacist or doctor before taking it.

Derived from cruciferous vegetables (such as cabbage, broccoli, Brussels sprouts) · Capsules, tablets, found naturally in cruciferous vegetables and some combination supplements

An interaction check asks whether these two react with each other — it does not ask whether Ascorbigen is a good idea for someone in your situation. Here is what our Ascorbigen record says about it on its own.

Ascorbigen: dosing

There is no established standard dose for ascorbigen. It has not been studied enough in humans to know a safe and effective amount.If you choose to use a product that contains ascorbigen, follow the directions on the label and do not exceed the recommended amount.

From our Ascorbigen monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ascorbigen monograph & all interactions
Medication

About Olaparib

What Is Olaparib Used For?

Brand name: Lynparza

Lynparza (olaparib) is used to treat adults with certain ovarian, fallopian tube, or primary peritoneal cancers that carry BRCA or other DNA-repair gene mutations — both as a maintenance therapy after platinum-based chemotherapy (including in combination with bevacizumab for some patients) and for recurrent disease. It is also approved for HER2-negative breast cancer with a germline BRCA mutation, both in early high-risk disease (adjuvant setting) and in metastatic disease.

Lynparza is additionally used as maintenance therapy for adults with germline BRCA-mutated metastatic pancreatic adenocarcinoma whose disease has not progressed on first-line platinum-based chemotherapy, and for adults with certain gene-mutated metastatic castration-resistant prostate cancer — either alone (after prior enzalutamide or abiraterone) or in combination with abiraterone and prednisone or prednisolone. All uses require testing for specific genetic mutations using an FDA-approved companion diagnostic before starting treatment.

Most-Reported Side Effects for Olaparib

From FAERS, the FDA’s public side-effect reporting system (20,798 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Malignant neoplasm progression 2,063 reports
Nausea 1,827 reports
Fatigue 1,762 reports
Anemia 1,622 reports
Vomiting 724 reports
See full Olaparib drug information
Keep checking

Other Drugs & Ascorbigen

Browse every other medication we’ve checked against Ascorbigen — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Ascorbigen against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Ascorbigen list.

See the full Ascorbigen interactions page
See every supplement checked against Olaparib, ranked by severity
Evidence & sources

Ascorbigen References

The 1 references that drive our Ascorbigen monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ascorbigen and Olaparib Together: Common Questions

Is it safe to take Ascorbigen with Olaparib?
We do not list a known interaction between Ascorbigen and Olaparib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Ascorbigen and Olaparib have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Ascorbigen and Olaparib used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Ascorbigen in each. That is a conversation for your prescriber, especially if Olaparib is being adjusted to a target.
Does Olaparib interact with any supplements?
Yes. Olaparib has documented interactions with 138 supplements in our database — Ascorbigen is not one of them. The Olaparib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Ascorbigen monograph Uses, safety profile, and every drug interaction in one place Olaparib drug information The full plain-English guide to this medication Olaparib supplement interactions Every supplement checked against Olaparib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Olaparib and Ascorbigen?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.