Drug & supplement interaction

Black Root + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Aluminum Hydroxide, Aspirin, Magnesium Hydroxide brand name: Ascriptin.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Black Root in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Black Root safety at a glance

Black Root overall Use caution Modern safety data are limited and the fresh root can cause significant digestive toxicity.
Pregnancy Possibly Unsafe When the fresh root is used orally. Anecdotally, fresh black root has been reported for have abortifacient and teratogenic effects. However, there is no reliabl... Read the full pregnancy detail
Breastfeeding Avoid Avoid while breastfeeding due to insufficient safety information.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Black Root? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide is filed under 9 classifications — including antacids, aspirin, nonsteroidal anti-inflammatory drugs (nsaids). Black Root has documented interactions with 3 drug classes — the most serious being digoxin (lanoxin) (moderate), diuretic drugs (moderate) and warfarin (coumadin) (moderate) — and none of Aluminum Hydroxide, Aspirin, Magnesium Hydroxide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Black Root Does Interact With Other Medications

Black Root has 78 moderate known drug interactions in our database — Aluminum Hydroxide, Aspirin, Magnesium Hydroxide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 78 No known interaction 2,752 (incl. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide)
Taking anything else?

Check Another of Your Medications Against Black Root

Covers the 2,830 medications we’ve checked against Black Root. Pick one to open its full report.

What to actually watch for

What Black Root Itself Has Been Linked To

This is not an interaction — nothing below involves Aluminum Hydroxide, Aspirin, Magnesium Hydroxide. It is the side-effect record for Black Root on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Black Root, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Liver problems Worth acting on Additional detail

    “Orally, black root can cause abdominal pain or cramps, changes in stool color or odor, drowsiness, headache, nausea, and vomiting. Hepatotoxicity has been reported after ingestion of large amounts.”

    Black Root · Natural Medicines adverse-effect record, reported in cluster headache.

    1 source cited
    1. 6002. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  • Drowsiness / Stomach pain / Vomiting / Headache / Nausea Additional detail

    Recorded for Black Root in the same Natural Medicines adverse-effect record shown under Liver problems above.

Everything above comes from the Natural Medicines adverse-effect record for Black Root — expand a row for the licensed statement it rests on. We haven’t matched Aluminum Hydroxide, Aspirin, Magnesium Hydroxide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Aluminum Hydroxide, Aspirin, Magnesium Hydroxide.

Special populations

Black Root in Pregnancy & Breastfeeding

Pregnancy Possibly Unsafe

When the fresh root is used orally. Anecdotally, fresh black root has been reported for have abortifacient and teratogenic effects. However, there is no reliable scientific evidence about the effects of black root on pregnancy. Until more is known, black root should not be used during pregnancy.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Black Root or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Black Root or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

This page covers Black Root only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page lists 255 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Piracetam (major).

By severity: 7 major · 211 moderate · 37 minor.

From our pharmacist’s overview on the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page

“Ascriptin combines aspirin with two antacids, aluminum hydroxide and magnesium hydroxide, and the aspirin part already thins the blood on its own. That is why more than 200 of the 255 ingredients listed here can raise bleeding risk, and why this page deserves a careful read rather than a quick skim.”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction page

One more smart check

Taking Black Root as Part of a Dietary Supplement Product? Check It for Interactions

We hold 41 real supplement products containing Black Root, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Black Root. Even though Black Root itself has no known interaction with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Black Root
Top half

#595 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aluminum Hydroxide, Aspirin, Magnesium Hydroxide
Top half

#1,408 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Black Root reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Black Root

What is Black Root?

  • Constipation
  • Liver and gallbladder complaints
  • Digestive upset
  • Stimulating bile flow

Black Root is a traditional North American herb that was historically used as a strong laxative and to support digestion and liver function. There is very little modern scientific evidence to support these uses, and the fresh root can be toxic, so it should be used cautiously, if at all, and never during pregnancy or breastfeeding.

Veronicastrum virginicum · Plantaginaceae · Dried root and rhizome · Dried root, tincture, liquid extract, capsules, tea

An interaction check asks whether these two react with each other — it does not ask whether Black Root is a good idea for someone in your situation. Here is what our Black Root record says about it on its own.

Black Root: dosing

There is no established, standardized dose for Black Root, and modern dosing guidelines are lacking. Traditional preparations used the dried, aged root rather than the fresh root.Because of the risk of toxicity and strong laxative effects, you should not guess at a dose.

From our Black Root monograph — the full record covers uses, side effects and every documented interaction.

Read the full Black Root monograph & all interactions
Medication

About Aspirin

What Is Aspirin Used For?

Brand name: Ascriptin

Aspirin is used to temporarily relieve minor aches and pains from headaches, backaches, muscle aches, toothaches, menstrual cramps, the common cold, and minor arthritis pain. It also temporarily reduces fever.

Some coated aspirin tablet products note that, under a doctor's supervision, aspirin can help prevent another heart attack or stroke in adults who have already had one. Because of their delayed-release design, those coated products will not give fast relief for headaches or other symptoms needing quick relief.

See full Aspirin drug information
Keep checking

Other Drugs & Black Root

Browse every other medication we’ve checked against Black Root — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
78Moderate
0Minor
2,751No known interaction
78 Moderate 2,751 No interaction
Moderate

78 interactions

Showing 60 of 78 moderate interactions — see all 78 on the Black Root page.

No interaction 2,751 drugs checked — show the list

We also checked Black Root against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,751 medications checked with no known interaction — see the full Black Root list.

See the full Black Root interactions page
See every supplement checked against Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, ranked by severity
Evidence & sources

Black Root References

The 2 references that drive our Black Root monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Together: Common Questions

Is it safe to take Black Root with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide?
We do not list a known interaction between Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Black Root and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide combination checked?
Interactions in our licensed database are recorded against drug classes. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide is filed under 9 classifications, and Black Root has documented interactions with 3 drug classes — none of Aluminum Hydroxide, Aspirin, Magnesium Hydroxide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Black Root interact with any other medications?
Yes. Black Root has 78 documented drug interactions in our database — Aluminum Hydroxide, Aspirin, Magnesium Hydroxide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interact with any supplements?
Yes. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide has documented interactions with 255 supplements in our database — Black Root is not one of them. The Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Black Root monograph Uses, safety profile, and every drug interaction in one place Aspirin drug information The full plain-English guide to this medication Aluminum Hydroxide, Aspirin, Magnesium Hydroxide supplement interactions Every supplement checked against Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Black Root?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.