Drug & supplement interaction

Bladderwort + Canagliflozin

Canagliflozin brand name: Invokana.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Bladderwort and Canagliflozin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Bladderwort and Canagliflozin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Canagliflozin and Bladderwort in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Bladderwort at all — not against Canagliflozin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Bladderwort safety at a glance

Bladderwort overall Not established There is almost no human safety data for bladderwort taken as a supplement.
Pregnancy Avoid No safety data exists, so it is best avoided during pregnancy.
Breastfeeding Avoid No safety data exists, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Canagliflozin and Bladderwort? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Canagliflozin’s Own FDA Label Lists

This is not an interaction — none of it involves Bladderwort. These are the most notable effects listed in the ADVERSE REACTIONS section of Canagliflozin’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Bone thinning Worth acting on
  • Dehydration Worth acting on
  • High blood sugar Worth acting on mentioned in 4.2% of FDA reports for Canagliflozin
  • High potassium Worth acting on
  • Low blood sugar Worth acting on
  • Pancreatitis Worth acting on
  • Heart failure Worth acting on
  • Kidney problems Worth acting on mentioned in 6.6% of FDA reports for Canagliflozin
  • Fainting Worth acting on
  • Seizures Worth acting on

Showing the 10 most notable of 26 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Canagliflozin. Read the label on DailyMed › Where a percentage is shown, it is the share of 31,055 voluntary FDA FAERS reports for Canagliflozin that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Bladderwort’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Bladderwort side to compare — that is a limit of the record, not a statement that Bladderwort has no side effects.

Everything else you take

See Every Supplement That Interacts With Canagliflozin

This page covers Bladderwort only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Canagliflozin page lists 256 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Siberian Cocklebur (major), Acai (moderate), African Wild Potato (moderate) and Agaricus Mushroom (moderate).

By severity: 2 major · 215 moderate · 39 minor.

From our pharmacist’s overview on the Canagliflozin page

“Canagliflozin (Invokana) lowers blood sugar, and that is precisely why this list deserves genuine care. Nearly every ingredient on it works on glucose one way or another: most can push it too low when stacked with the drug, while a few, niacin among them, raise it and work against the medicine.”

Reviewed by 2 · Jul 18, 2026

Open the Canagliflozin interaction page

How much people look this up

Where Bladderwort and Canagliflozin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Bladderwort
Steady interest

#749 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Canagliflozin
Top half

#898 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Bladderwort is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Bladderwort reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Bladderwort and Canagliflozin records this page draws on were last updated June 20, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Bladderwort

What is Bladderwort?

  • Wound care and skin irritation (traditional)
  • Urinary complaints (traditional)
  • General 'detox' or tonic claims
  • Coughs and respiratory complaints (folk use)

Bladderwort is a group of small carnivorous wetland plants (Utricularia) that have been used in some folk traditions, but there is very little human research to support any health benefit. Because its safety, effectiveness, and proper dose have not been studied in people, it is hard to recommend, and you should talk to a pharmacist or doctor before trying it.

Utricularia spp. · Lentibulariaceae · Whole plant (above-ground parts), traditionally used fresh or dried · Dried herb, teas/infusions, tinctures, and topical preparations (availability is very limited)

An interaction check asks whether these two react with each other — it does not ask whether Bladderwort is a good idea for someone in your situation. Here is what our Bladderwort record says about it on its own.

Bladderwort: dosing

There is no established or standardized dose for bladderwort. Because it has not been studied in people, no safe and effective amount has been defined.If you choose to use a commercial product, follow the directions on the label and do not exceed them.

From our Bladderwort monograph — the full record covers uses, side effects and every documented interaction.

Read the full Bladderwort monograph & all interactions
Medication

About Canagliflozin

What Is Canagliflozin Used For?

Brand name: Invokana

Invokana (canagliflozin) is used alongside diet and exercise to improve blood sugar control in adults and children aged 10 and older with type 2 diabetes. It is not for type 1 diabetes.

In adults with type 2 diabetes, Invokana is also used to lower the risk of heart attack, stroke, and cardiovascular death in those with established cardiovascular disease, and to reduce the risk of serious kidney complications — including end-stage kidney disease, cardiovascular death, and hospitalization for heart failure — in those with diabetic kidney disease and high levels of protein in the urine.

Most-Reported Side Effects for Canagliflozin

From FAERS, the FDA’s public side-effect reporting system (31,055 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diabetic ketoacidosis 3,520 reports
Toe amputation 2,263 reports
Osteomyelitis 2,233 reports
Acute kidney injury 2,038 reports
Fungal infection 1,490 reports
See full Canagliflozin drug information
Keep checking

Other Drugs & Bladderwort

Browse every other medication we’ve checked against Bladderwort — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Bladderwort References

The 1 sources that drive our Bladderwort monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Bladderwort is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.

  1. Using Dietary Supplements Wisely — NIH NCCIH Source

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Bladderwort and Canagliflozin Together: Common Questions

Is it safe to take Bladderwort with Canagliflozin?
We do not list a known interaction between Bladderwort and Canagliflozin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Canagliflozin interact with any supplements?
Yes. Canagliflozin has documented interactions with 256 supplements in our database — Bladderwort is not one of them. The Canagliflozin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Canagliflozin and Bladderwort?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.