Drug & supplement interaction

Celery + Caramiphen Edisylate, Phenylpropanolamine

Caramiphen Edisylate, Phenylpropanolamine brand names: Ordrine AT, Tuss-Ornade.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Celery and Caramiphen Edisylate, Phenylpropanolamine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Celery and Caramiphen Edisylate, Phenylpropanolamine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Caramiphen Edisylate, Phenylpropanolamine and Celery in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Celery safety at a glance

Celery overall Use caution Generally safe as food, but concentrated supplements and allergy risk call for some caution.
Pregnancy Likely Unsafe When celery oil or seeds are used orally in larger amounts; celery might have uterine stimulant or abortifacient effects. Read the full pregnancy detail
Breastfeeding Use caution Not enough reliable information on celery supplements while breastfeeding, so it is best avoided.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Caramiphen Edisylate, Phenylpropanolamine and Celery? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Caramiphen Edisylate, Phenylpropanolamine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Caramiphen Edisylate, Phenylpropanolamine is filed under 4 classifications — including phenylpropanolamine, alpha-adrenergic agonists, stimulant drugs. Celery has documented interactions with 8 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate), antihypertensive drugs (moderate) and cytochrome p450 1a2 (cyp1a2) substrates (moderate) — and none of Caramiphen Edisylate, Phenylpropanolamine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Celery Does Interact With Other Medications

Celery has 449 moderate, 202 minor known drug interactions in our database — Caramiphen Edisylate, Phenylpropanolamine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Celery

Covers the 2,830 medications we’ve checked against Celery. Pick one to open its full report.

What to actually watch for

What Celery Itself Has Been Linked To

This is not an interaction — nothing below involves Caramiphen Edisylate, Phenylpropanolamine. It is the side-effect record for Celery on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Celery, this list is the first place to look. 4 entries are worth acting on rather than waiting out — marked below.

  • A change in thyroid levels Worth acting on Additional detail

    “Celery has been associated with hyperthyroidism in otherwise healthy adults. In one case report a 36-year-old female presented with weight loss, blurred vision, nausea, palpitations, sweating, exophthalmos, elevated serum T4 levels, and low thyroid stimulating hormone (TSH) levels after taking 8 grams of a powdered celery extract for 78 days.”

    Celery · Natural Medicines adverse-effect record, reported in dry skin.

    3 sources cited
    1. 102912. Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. Effect of celery extract on thyroid function; is herbal therapy safe in obesity? Int J Prev Med 2019;10:55. doi: 10.4103/ijpvm.IJPVM_209_17. PubMed
    2. 102914. Rouhi-Boroujeni H, Hosseini M, Gharipour M, Rouhi-Boroujeni H. Is herbal therapy safe in obesity? A case of Apium graveolens (Celery) induced hyperthyroidism. ARYA Atheroscler 2016;12(5):248-9.
    3. 10646. Moses, G. Thyroxine interacts with celery seed tablets? Australian Prescriber 2001;24:6-7. DOI
  • Wheezing / Shortness of breath / An allergic reaction Worth acting on Additional detail

    “Raw celery, cooked celery, and celery juice can all cause allergic reactions. Symptoms of celery allergy include laryngeal edema, skin reactions, nasal congestion and discharge, an urticaria-edema-anaphylactic shock syndrome, celery-dependent exercise-induced anaphylaxis, and anaphylactic shock.”

    Celery · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    6 sources cited
    1. 40908. Rueff, F., Eberlein-Konig, B., and Przybilla, B. Oral hyposensitization with celery juice. Allergy 2001;56(1):82-83. PubMed
    2. 40926. Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy PubMed
    3. 41118. Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Ann.Allergy 1984;53(6 Pt 2):665-672.
    4. 41131. Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery]. Allerg.Immunol.(Paris) 1995;27(6):209.
    5. 92852. Baek CH, Bae YJ, Cho YS, Moon HB, Kim TB. Food-dependent exercise-induced anaphylaxis in the celery-mugwort-birch-spice syndrome. Allergy. 2010;65(6):792-3. PubMed
    6. 92855. Palgan K, Götz-Zbikowska M, Tykwinska M, Napiórkowska K, Bartuzi Z. Celery-cause of severe anaphylactic shock. Postepy Hig Med Dosw (Online). 2012;66:132-4.
  • A severe allergic reaction Worth acting on Additional detail

    “Orally, celery seems to be well tolerated.

    Most Common Adverse Effects:

    Orally: Photosensitivity. Oral allergy syndrome in sensitive individuals.

    Topically: Photosensitivity. Contact dermatitis in sensitive individuals.

    Serious Adverse Effects (Rare):

    Orally: Anaphylaxis in sensitive individuals.”

    Celery · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

  • Hives Worth acting on Additional detail

    “Due to its psoralen content, contact with or ingestion of celery and exposure to ultraviolet radiation may cause photodermatitis (4,34347,40968,40969,40986,41085,41087,41143,41146,41151). Acute symptoms include skin eruption with edema and erythema; the main chronic symptom is hyperpigmentation at the eruption site.

    Celery can also cause contact or atopic dermatitis (19,41118,41124) and urticaria pigmentosa.”

    Celery · Natural Medicines adverse-effect record, reported in dermatitis.

    6 sources cited
    1. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
    2. 34347. Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
    3. 40968. DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed
    4. 40969. Groot, B. J., Belinfante-van Gelder, M. E., and Jans, H. W. [An epidemic of dermatitis caused by blanched celery]. Ned.Tijdschr.Geneeskd. 6-20-1992;136(25):1210-1213.
    5. 40986. Jeanmougin, M., Varroud-Vial, C., and Dubertret, L. [Phototoxic side-effect following celery ingestion during puvatherapy]. Ann.Dermatol Venereol 2005;132(6-7 Pt 1):566-567.
    6. 41085. Maso, M. J., Ruszkowski, A. M., Bauerle, J., DeLeo, V. A., and Gasparro, F. P. Celery phytophotodermatitis in a chef. Arch.Dermatol. 1991;127(6):912-913. DOI
  • Dry skin / Weight loss Additional detail

    Recorded for Celery in the same Natural Medicines adverse-effect record shown under A change in thyroid levels above.

  • Sun sensitivity Additional detail

    Recorded for Celery in the same Natural Medicines adverse-effect record shown under A severe allergic reaction above.

  • Mouth irritation or sores Additional detail

    “Symptoms of celery allergy have included oral allergy syndrome, characterized by itching and burning in the mouth and throat, and laryngeal edema.”

    Celery · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    4 sources cited
    1. 41159. Wuthrich, B., Borga, A., and Yman, L. Oral allergy syndrome to a jackfruit (Artocarpus integrifolia). Allergy 1997;52(4):428-431.
    2. 40977. Erdmann, S. M., Sachs, B., Schmidt, A., Merk, H. F., Scheiner, O., Moll-Slodowy, S., Sauer, I., Kwiecien, R., Maderegger, B., and Hoffmann-Sommergruber, K. In vitro analysis of birch-pollen-associated food allergy by use of recombinant allergens in the b
    3. 115301. Ukleja-Sokolowska N, Lis K, Graczyk M, Bartuzi M, Bartuzi Z. The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report. Int J Immunopathol Pharmacol 2024;38:3946320231223004. PubMed
    4. 40953. Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. Am.J.Emerg.Med. 1992;10(6):613. PubMed

Showing the 10 most notable of 22 recorded effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

Everything above comes from the Natural Medicines adverse-effect record for Celery — expand a row for the licensed statement it rests on. We haven’t matched Caramiphen Edisylate, Phenylpropanolamine to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Caramiphen Edisylate, Phenylpropanolamine.

Special populations

Celery in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When celery oil or seeds are used orally in larger amounts; celery might have uterine stimulant or abortifacient effects.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Caramiphen Edisylate, Phenylpropanolamine

This page covers Celery only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Caramiphen Edisylate, Phenylpropanolamine page lists 62 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Ephedra (major), Peyote (major), Rauvolfia Vomitoria (major) and Sida Cordifolia (major).

By severity: 5 major · 44 moderate · 13 minor.

Open the Caramiphen Edisylate, Phenylpropanolamine interaction page

One more smart check

Taking Celery as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,687 real supplement products containing Celery, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Celery. Even though Celery itself has no known interaction with Caramiphen Edisylate, Phenylpropanolamine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Celery and Caramiphen Edisylate, Phenylpropanolamine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Celery
Top 25%

#168 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Caramiphen Edisylate, Phenylpropanolamine
Top 5%

#117 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Celery reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Celery and Caramiphen Edisylate, Phenylpropanolamine records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Celery

What is Celery?

Celery
  • High blood pressure
  • Fluid retention (diuretic)
  • Joint pain and inflammation
  • Anxiety and sleep
  • Digestive support

Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement uses is limited and mostly preliminary, so it should not replace proven treatments. Celery is generally safe as food, but concentrated supplements and possible allergic reactions warrant caution.

Apium graveolens · Apiaceae · Stalks, seeds, and seed oil (sometimes the whole plant and root) · Fresh vegetable, juice, seed powder, capsules, tablets, and seed oil extract

An interaction check asks whether these two react with each other — it does not ask whether Celery is a good idea for someone in your situation. Here is what our Celery record says about it on its own.

Celery: dosing

There is no official or well-established standardized dose for celery supplements. Products vary widely in strength, especially celery seed extracts and oils.The safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Celery monograph — the full record covers uses, side effects and every documented interaction.

Read the full Celery monograph & all interactions
Keep checking

Other Drugs & Celery

Browse every other medication we’ve checked against Celery — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
449Moderate
202Minor
2,178No known interaction
Moderate

449 interactions

Showing 60 of 449 moderate interactions — see all 449 on the Celery page.

Minor

202 interactions

Showing 60 of 202 minor interactions — see all 202 on the Celery page.

No interaction 2,178 drugs checked — show the list
Evidence & sources

Celery References

The 48 references that drive our Celery monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  5. Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
  6. Moses, G. Thyroxine interacts with celery seed tablets? Australian Prescriber 2001;24:6-7. DOI
  7. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  8. Jakovljevic, V., Raskovic, A., Popovic, M., and Sabo, J. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. Eur.J Drug Metab Pharmacokinet. 2002;27(3):153-156. PubMed
  9. Wang, L., Sterling, B., and Don, P. Berloque dermatitis induced by "Florida water". Cutis 2002;70(1):29-30.
  10. Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
  11. Rueff, F., Eberlein-Konig, B., and Przybilla, B. Oral hyposensitization with celery juice. Allergy 2001;56(1):82-83. PubMed
  12. Lombaert, G. A., Siemens, K. H., Pellaers, P., Mankotia, M., and Ng, W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int 2001;84(4):1135-1143. DOI
  13. Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy PubMed
  14. Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. Am.J.Emerg.Med. 1992;10(6):613. PubMed
  15. DeLeo, V. A. Photocontact dermatitis. Dermatol Ther 2004;17(4):279-288. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Celery and Caramiphen Edisylate, Phenylpropanolamine Together: Common Questions

Is it safe to take Celery with Caramiphen Edisylate, Phenylpropanolamine?
We do not list a known interaction between Celery and Caramiphen Edisylate, Phenylpropanolamine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Celery and Caramiphen Edisylate, Phenylpropanolamine combination checked?
Interactions in our licensed database are recorded against drug classes. Caramiphen Edisylate, Phenylpropanolamine is filed under 4 classifications, and Celery has documented interactions with 8 drug classes — none of Caramiphen Edisylate, Phenylpropanolamine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Celery interact with any other medications?
Yes. Celery has 651 documented drug interactions in our database — Caramiphen Edisylate, Phenylpropanolamine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Caramiphen Edisylate, Phenylpropanolamine interact with any supplements?
Yes. Caramiphen Edisylate, Phenylpropanolamine has documented interactions with 62 supplements in our database — Celery is not one of them. The Caramiphen Edisylate, Phenylpropanolamine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Caramiphen Edisylate, Phenylpropanolamine and Celery?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.