Drug & supplement interaction

Combretum Micranthum + Erlotinib

Erlotinib brand name: Tarceva.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 27, 2026
The bottom line No known interaction

We found no known interaction between Combretum Micranthum and Erlotinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Erlotinib states a food rule worth keeping to.

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Interaction report

Combretum Micranthum and Erlotinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Erlotinib and Combretum Micranthum in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Combretum Micranthum safety at a glance

Combretum Micranth... overall Use caution Used widely as a traditional tea, but human safety data are very limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data while breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Erlotinib and Combretum Micranthum? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Erlotinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Erlotinib is filed under 2 classifications — including oral drugs. Combretum Micranthum has documented interactions with 3 drug classes — the most serious being antidiabetes drugs (moderate), antihypertensive drugs (moderate) and diuretic drugs (moderate) — and none of Erlotinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Combretum Micranthum Does Interact With Other Medications

Combretum Micranthum has 265 moderate known drug interactions in our database — Erlotinib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 265 No known interaction 2,565 (incl. Erlotinib)
Taking anything else?

Check Another of Your Medications Against Combretum Micranthum

Covers the 2,830 medications we’ve checked against Combretum Micranthum. Pick one to open its full report.

What to actually watch for

What Combretum Micranthum Itself Has Been Linked To

This is not an interaction — nothing below involves Erlotinib. It is the side-effect record for Combretum Micranthum on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Combretum Micranthum, this list is the first place to look.

  • Passing urine more often / Trouble sleeping Additional detail

    “Orally, nocturia resulting in insomnia has been reported rarely.”

    Combretum Micranthum · Natural Medicines adverse-effect record, reported in insomnia.

    1 source cited
    1. 106180. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
  • Stomach pain Additional detail

    “Orally, abdominal pain has been reported.”

    Combretum Micranthum · Natural Medicines adverse-effect record, reported in pain.

    2 sources cited
    1. 106180. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
    2. 106191. Seck SM, Doupa D, Dia DG, et al. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. J Hum Hypertens 2017;32(1):75-81. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Combretum Micranthum — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Erlotinib’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Erlotinib column appears here.

How to take them

Some Erlotinib Products Have a Food Rule — Combretum Micranthum Should Not Break It

At least one FDA label for a product containing Erlotinib says to take it on an empty stomach. Most supplements — Combretum Micranthum included — are taken with a meal, so the easy mistake is swallowing both together at breakfast. Where that rule applies, keep Erlotinib on its own and move Combretum Micranthum to a meal later in the day.

This may not be true of your version. Food instructions belong to the product, not the ingredient: two Erlotinib products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.

Recommended Dose – NSCLC The recommended daily dose of erlotinib tablets for NSCLC is 150 mg taken on an empty stomach, i.e., at least one hour before or two hours after the ingestion of food.

From the Dosage and Administration section of the FDA label we read for Erlotinib — where that label names a specific product, the instruction is that product's. See the Erlotinib drug page ›

A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.

Everything else you take

See Every Supplement That Interacts With Erlotinib

This page covers Combretum Micranthum only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Erlotinib page lists 18 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Bilberry (moderate), Coffee Charcoal (moderate), European Mandrake (moderate) and Glucomannan (moderate).

By severity: 1 major · 8 moderate · 9 minor.

From our pharmacist’s overview on the Erlotinib page

“Activated charcoal is the entry I would flag first for anyone taking erlotinib (Tarceva), an oral targeted therapy for certain lung cancers. Charcoal can adsorb the drug in the gut and cut how much reaches the bloodstream, and with a cancer pill, less absorbed means less cancer fought.”

Reviewed by 2 · Jul 18, 2026

Open the Erlotinib interaction page

How much people look this up

Where Combretum Micranthum and Erlotinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Combretum Micranthum
Top half

#612 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Erlotinib
Steady interest

#2,520 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Combretum Micranthum reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Combretum Micranthum and Erlotinib records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Combretum Micranthum

What is Combretum Micranthum?

Combretum Micranthum
  • Digestive upset
  • Liver and gallbladder support
  • Fever
  • Weight management
  • Mild urinary or fluid retention
  • Traditional opium withdrawal aid

Combretum micranthum (kinkeliba) is a West African shrub whose leaves are brewed into a traditional tea for digestion, liver complaints, and fever. Solid human studies are lacking, so its benefits remain unproven, and people who are pregnant, breastfeeding, or have liver or kidney problems should be cautious and talk to a healthcare professional first.

Combretum micranthum · Combretaceae · Leaves (mainly), and sometimes stems and roots · Tea (herbal infusion or decoction), dried leaf powder, capsules, liquid extracts

An interaction check asks whether these two react with each other — it does not ask whether Combretum Micranthum is a good idea for someone in your situation. Here is what our Combretum Micranthum record says about it on its own.

Combretum Micranthum: dosing

There is no established standardized dose for Combretum micranthum. Traditionally, a handful of dried leaves is steeped in hot water to make a tea, but the strength varies widely from one preparation to another.If you choose to use a commercial product, follow the directions on the label and do not exceed the recommended amount.

From our Combretum Micranthum monograph — the full record covers uses, side effects and every documented interaction.

Read the full Combretum Micranthum monograph & all interactions
Medication

About Erlotinib

What Is Erlotinib Used For?

Brand name: Tarceva

Erlotinib tablets are used to treat metastatic non-small cell lung cancer (NSCLC) in patients whose tumors carry specific gene changes — EGFR exon 19 deletions or exon 21 (L858R) mutations — confirmed by an FDA-approved test. It can be used as a first-line treatment, as maintenance therapy, or after at least one prior chemotherapy has stopped working.

Erlotinib tablets are also used for the first-line treatment of locally advanced, unresectable, or metastatic pancreatic cancer — but only in combination with another chemotherapy drug called gemcitabine. Erlotinib is not recommended alongside platinum-based chemotherapy regimens.

Most-Reported Side Effects for Erlotinib

From FAERS, the FDA’s public side-effect reporting system (12,441 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Diarrhea 1,339 reports
Rash 1,317 reports
Malignant neoplasm progression 890 reports
Fatigue 718 reports
Nausea 696 reports
See full Erlotinib drug information
Keep checking

Other Drugs & Combretum Micranthum

Browse every other medication we’ve checked against Combretum Micranthum — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
265Moderate
0Minor
2,564No known interaction
265 Moderate 2,564 No interaction
Moderate

265 interactions

Showing 60 of 265 moderate interactions — see all 265 on the Combretum Micranthum page.

No interaction 2,564 drugs checked — show the list

We also checked Combretum Micranthum against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,564 medications checked with no known interaction — see the full Combretum Micranthum list.

See the full Combretum Micranthum interactions page
See every supplement checked against Erlotinib, ranked by severity
Evidence & sources

Combretum Micranthum References

The 4 references that drive our Combretum Micranthum monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Bourqui A, Niang EAB, Graz B, et al. Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. J Hum Hypertens 2020. PubMed
  2. Kpemissi M, Potârniche AV, Lawson-Evi P, et al. Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and in-silico experiments. J Ethnopharmacol 2020;261:113133. PubMed
  3. Chika A, Bello SO. Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats. J Ethnopharmacol 2010;129(1):34-7. PubMed
  4. Seck SM, Doupa D, Dia DG, et al. Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. J Hum Hypertens 2017;32(1):75-81. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Combretum Micranthum and Erlotinib Together: Common Questions

Is it safe to take Combretum Micranthum with Erlotinib?
We do not list a known interaction between Combretum Micranthum and Erlotinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Should I take Combretum Micranthum and Erlotinib at the same time of day?
At least one FDA label for a product containing Erlotinib says to take it on an empty stomach, and supplements are usually taken with a meal — so taking them together at breakfast is the easy mistake. Where that applies, keep Erlotinib on its own and move Combretum Micranthum to a meal later in the day. Food instructions belong to the product rather than the ingredient, so check the directions on your own box. This is about absorption, not an interaction.
How was the Combretum Micranthum and Erlotinib combination checked?
Interactions in our licensed database are recorded against drug classes. Erlotinib is filed under 2 classifications, and Combretum Micranthum has documented interactions with 3 drug classes — none of Erlotinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Combretum Micranthum interact with any other medications?
Yes. Combretum Micranthum has 265 documented drug interactions in our database — Erlotinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Erlotinib interact with any supplements?
Yes. Erlotinib has documented interactions with 18 supplements in our database — Combretum Micranthum is not one of them. The Erlotinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Combretum Micranthum monograph Uses, safety profile, and every drug interaction in one place Erlotinib drug information The full plain-English guide to this medication Erlotinib supplement interactions Every supplement checked against Erlotinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Erlotinib and Combretum Micranthum?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.