Drug & supplement interaction

Corn Poppy + Relugolix

Relugolix brand name: Orgovyx.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Corn Poppy and Relugolix in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Corn Poppy and Relugolix

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Relugolix and Corn Poppy in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Corn Poppy safety at a glance

Corn Poppy overall Use caution Generally low in strong alkaloids, but human safety data are limited and it should be used cautiously.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Relugolix and Corn Poppy? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Relugolix

Interactions in our licensed database are recorded against drug classes, not just single drug names. Relugolix is filed under 4 classifications — including qt interval-prolonging drugs, p-glycoprotein substrates, cytochrome p450 3a4 (cyp3a4) substrates. Corn Poppy has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Relugolix’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Corn Poppy Does Interact With Other Medications

Corn Poppy has 248 moderate known drug interactions in our database — Relugolix isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Relugolix)
Taking anything else?

Check Another of Your Medications Against Corn Poppy

Covers the 2,830 medications we’ve checked against Corn Poppy. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Corn Poppy and Relugolix May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. One of them is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    Corn Poppy

    “Topically, corn poppy flowers may cause allergic contact urticaria.”

    Corn Poppy · Natural Medicines adverse-effect record, reported in urticaria.

    1 source cited
    1. 46284. Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

    Relugolix

    Listed in the ADVERSE REACTIONS section of the FDA label for Relugolix. Read the label on DailyMed ›

Effects for Relugolix come from the ADVERSE REACTIONS section of its FDA label; effects for Corn Poppy come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 24,018 voluntary FDA FAERS reports for Relugolix that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Corn Poppy or Relugolix

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Corn Poppy or Relugolix, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Relugolix

This page covers Corn Poppy only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Relugolix page lists 152 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 107 moderate · 37 minor.

From our pharmacist’s overview on the Relugolix page

“Relugolix (Orgovyx) shuts down testosterone to treat prostate cancer, and I would handle its supplement list with genuine care, since 8 of the 152 entries carry a major rating. The bulk of the list, 121 ingredients, can change how much relugolix stays in your blood by acting on the CYP3A4 enzyme that clears it.”

Reviewed by 2 · Jul 18, 2026

Open the Relugolix interaction page

One more smart check

Taking Corn Poppy as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Corn Poppy, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Corn Poppy. Even though Corn Poppy itself has no known interaction with Relugolix, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Corn Poppy and Relugolix Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Corn Poppy
Steady interest

#927 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Relugolix
Steady interest

#1,683 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Corn Poppy reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Corn Poppy and Relugolix records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Corn Poppy

What is Corn Poppy?

Corn Poppy
  • Cough and sore throat
  • Sleep and restlessness
  • Mild pain
  • Anxiety and nervousness
  • Digestive complaints

Corn poppy is a red-flowered plant traditionally used in teas and syrups for cough, sleep, and mild pain. Solid human research is very limited, so its benefits are not well proven, and unlike its relative the opium poppy, it contains only small amounts of weak alkaloids. Talk to a pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Papaver rhoeas · Papaveraceae · Flowers (petals) and leaves · Tea, syrup, dried petals, tincture, capsules

An interaction check asks whether these two react with each other — it does not ask whether Corn Poppy is a good idea for someone in your situation. Here is what our Corn Poppy record says about it on its own.

Corn Poppy: dosing

There is no well-established or standardized dose for corn poppy. Traditional use generally involves small amounts of the dried petals made into a tea or syrup.Because products vary widely in strength, follow the directions on the product label and do not exceed the suggested amount. Avoid giving it to infants or young children.

From our Corn Poppy monograph — the full record covers uses, side effects and every documented interaction.

Read the full Corn Poppy monograph & all interactions
Medication

About Relugolix

What Is Relugolix Used For?

Brand name: Orgovyx

Orgovyx (relugolix) tablets are used to treat advanced prostate cancer in adults. It works by sharply lowering testosterone levels, which helps slow the growth of prostate cancer cells that depend on testosterone to grow.

Most-Reported Side Effects for Relugolix

From FAERS, the FDA’s public side-effect reporting system (24,939 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Hot flush 7,500 reports
Fatigue 5,784 reports
Therapy interrupted 3,831 reports
Asthenia 1,930 reports
Arthralgia 1,564 reports
See full Relugolix drug information
Keep checking

Other Drugs & Corn Poppy

Browse every other medication we’ve checked against Corn Poppy — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
248 Moderate 2,581 No interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Corn Poppy page.

No interaction 2,581 drugs checked — show the list

We also checked Corn Poppy against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Corn Poppy list.

See the full Corn Poppy interactions page
See every supplement checked against Relugolix, ranked by severity
Evidence & sources

Corn Poppy References

The 2 references that drive our Corn Poppy monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Soulimani, R., Younos, C., Jarmouni-Idrissi, S., Bousta, D., Khalouki, F., and Laila, A. Behavioral and pharmaco-toxicological study of Papaver rhoeas L. in mice. J Ethnopharmacol 3-3-2001;74(3):265-274. PubMed
  2. Gamboa, P. M., Jauregui, I., Urrutia, I., Gonzalez, G., Barturen, P., and Antepara, I. Allergic contact urticaria from poppy flowers (Papaver rhoeas). Contact Dermatitis 1997;37(3):140-141.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Corn Poppy and Relugolix Together: Common Questions

Is it safe to take Corn Poppy with Relugolix?
We do not list a known interaction between Corn Poppy and Relugolix. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Corn Poppy and Relugolix have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Corn Poppy and Relugolix combination checked?
Interactions in our licensed database are recorded against drug classes. Relugolix is filed under 4 classifications, and Corn Poppy has documented interactions with 1 drug class — none of Relugolix's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Corn Poppy interact with any other medications?
Yes. Corn Poppy has 248 documented drug interactions in our database — Relugolix is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Relugolix interact with any supplements?
Yes. Relugolix has documented interactions with 152 supplements in our database — Corn Poppy is not one of them. The Relugolix interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Corn Poppy monograph Uses, safety profile, and every drug interaction in one place Relugolix drug information The full plain-English guide to this medication Relugolix supplement interactions Every supplement checked against Relugolix, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Relugolix and Corn Poppy?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.