Drug & supplement interaction

Deer Velvet + Naltrexone Hydrochloride

Naltrexone Hydrochloride brand name: Revia.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Deer Velvet and Naltrexone Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Deer Velvet and Naltrexone Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Naltrexone Hydrochloride and Deer Velvet in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Deer Velvet safety at a glance

Deer Velvet overall Use caution It appears generally well tolerated in short-term use, but long-term safety and product quality are not well studied.
Pregnancy Avoid There is not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Naltrexone Hydrochloride and Deer Velvet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Naltrexone Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Naltrexone Hydrochloride is filed under 3 classifications — including hepatotoxic drugs, oral drugs. Deer Velvet has documented interactions with 2 drug classes — the most serious being contraceptive drugs (minor) and estrogens (minor) — and none of Naltrexone Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Deer Velvet Does Interact With Other Medications

Deer Velvet has 52 minor known drug interactions in our database — Naltrexone Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Deer Velvet

Covers the 2,830 medications we’ve checked against Deer Velvet. Pick one to open its full report.

What to actually watch for

What Naltrexone Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves Deer Velvet. These are the most notable effects listed in the ADVERSE REACTIONS section of Naltrexone Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Dependence or withdrawal symptoms Worth acting on
  • A stroke or mini-stroke Worth acting on
  • A bowel blockage Worth acting on
  • Dehydration Worth acting on
  • A heart attack Worth acting on
  • Blood clots Worth acting on
  • Pancreatitis Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • An irregular heartbeat Worth acting on

Showing the 10 most notable of 62 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Naltrexone Hydrochloride. Read the label on DailyMed › Where a percentage is shown, it is the share of 9,867 voluntary FDA FAERS reports for Naltrexone Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Deer Velvet’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Deer Velvet side to compare — that is a limit of the record, not a statement that Deer Velvet has no side effects.

Everything else you take

See Every Supplement That Interacts With Naltrexone Hydrochloride

This page covers Deer Velvet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Naltrexone Hydrochloride page lists 56 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Ashwagandha (moderate).

Open the Naltrexone Hydrochloride interaction page

One more smart check

Taking Deer Velvet as Part of a Dietary Supplement Product? Check It for Interactions

We hold 249 real supplement products containing Deer Velvet, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Deer Velvet. Even though Deer Velvet itself has no known interaction with Naltrexone Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Deer Velvet and Naltrexone Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Deer Velvet
Top half

#496 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Naltrexone Hydrochloride
Steady interest

#2,513 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Deer Velvet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Deer Velvet and Naltrexone Hydrochloride records this page draws on were last updated July 3, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Deer Velvet

What is Deer Velvet?

Deer Velvet
  • Athletic performance and strength
  • Energy and fatigue
  • Joint health and arthritis
  • Immune support
  • Sexual function and libido

Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance, and joint health. Good-quality human evidence is limited, and most claims are not well proven. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Cervus nippon · Cervidae · Soft, growing antler (velvet) tissue, including the skin, cartilage, and bone, from male deer or elk · Capsules, tablets, powders, extracts, sprays, and teas

An interaction check asks whether these two react with each other — it does not ask whether Deer Velvet is a good idea for someone in your situation. Here is what our Deer Velvet record says about it on its own.

Deer Velvet: dosing

There is no standardized or well-established dose for deer velvet. Products differ widely in strength, form, and how they are processed, so amounts on labels are not consistent.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.

From our Deer Velvet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Deer Velvet monograph & all interactions
Medication

About Naltrexone

What Is Naltrexone Used For?

Brand name: Revia

Naltrexone Hydrochloride tablets are used to treat alcohol dependence and to block the effects of opioids in people being treated for opioid dependence. It works best as part of a full treatment program that includes counseling and support.

The extended-release injectable suspension (brand name Vivitrol) is used to treat alcohol dependence in patients who are already not drinking before starting treatment, and to prevent relapse to opioid dependence after a patient has completed opioid detoxification. Vivitrol must always be part of a comprehensive treatment program that includes psychosocial support.

See full Naltrexone drug information
Keep checking

Other Drugs & Deer Velvet

Browse every other medication we’ve checked against Deer Velvet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
52Minor
2,777No known interaction
Minor

52 interactions

No interaction 2,777 drugs checked — show the list
Evidence & sources

Deer Velvet References

The 2 references that drive our Deer Velvet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Sleivert, G., Burke, V., Palmer, C., Walmsley, A., Gerrard, D., Haines, S., and Littlejohn, R. The effects of deer antler velvet extract or powder supplementation on aerobic power, erythropoiesis, and muscular strength and endurance characteristics. Int PubMed
  2. Bubenik, G. A., Miller, K. V., Lister, A. L., Osborn, D. A., Bartos, L., and van der Kraak, G. J. Testosterone and estradiol concentrations in serum, velvet skin, and growing antler bone of male white-tailed deer. J Exp Zoolog.A Comp Exp Biol 3-1-2005;30 PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Deer Velvet and Naltrexone Hydrochloride Together: Common Questions

Is it safe to take Deer Velvet with Naltrexone Hydrochloride?
We do not list a known interaction between Deer Velvet and Naltrexone Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Deer Velvet and Naltrexone Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Naltrexone Hydrochloride is filed under 3 classifications, and Deer Velvet has documented interactions with 2 drug classes — none of Naltrexone Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Deer Velvet interact with any other medications?
Yes. Deer Velvet has 52 documented drug interactions in our database — Naltrexone Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Naltrexone Hydrochloride interact with any supplements?
Yes. Naltrexone Hydrochloride has documented interactions with 56 supplements in our database — Deer Velvet is not one of them. The Naltrexone Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Naltrexone Hydrochloride and Deer Velvet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.