Drug & supplement interaction

Dragon Fruit + Mifepristone

Mifepristone brand names: Mifeprex, Korlym.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Dragon Fruit and Mifepristone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Dragon Fruit and Mifepristone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Mifepristone and Dragon Fruit in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Dragon Fruit safety at a glance

Dragon Fruit overall Generally safe Dragon fruit is widely eaten as a food and is generally safe for most people.
Pregnancy Use caution The fruit as food is generally fine, but concentrated supplements or extracts have not been studied in pregnancy, so use caution.
Breastfeeding Use caution The fruit is considered fine in normal food amounts, but supplement forms lack safety data, so use caution.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Mifepristone and Dragon Fruit? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Mifepristone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Mifepristone is filed under 4 classifications — including qt interval-prolonging drugs, cytochrome p450 3a4 (cyp3a4) inhibitors, cytochrome p450 3a4 (cyp3a4) substrates. Dragon Fruit has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Mifepristone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Dragon Fruit Does Interact With Other Medications

Dragon Fruit has 86 moderate known drug interactions in our database — Mifepristone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Mifepristone)
Taking anything else?

Check Another of Your Medications Against Dragon Fruit

Covers the 2,830 medications we’ve checked against Dragon Fruit. Pick one to open its full report.

What to actually watch for

What Dragon Fruit Itself Has Been Linked To

This is not an interaction — nothing below involves Mifepristone. It is the side-effect record for Dragon Fruit on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Dragon Fruit, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    “Allergy to dragon fruit has been reported in case reports with symptoms including vomiting, swollen tongue, skin redness, and hives.”

    Dragon Fruit · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    1 source cited
    1. 93930. Kleinheinz A, Lepp U, Hausen BM, Petersen A, Becker WM. Anaphylactic reaction to (mixed) fruit juice containing dragon fruit. J Allergy Clin Immunol. 2009 Oct;124(4):841-2. PubMed
  • Vomiting Additional detail

    Recorded for Dragon Fruit in the same Natural Medicines adverse-effect record shown under Hives above.

Everything above comes from the Natural Medicines adverse-effect record for Dragon Fruit — expand a row for the licensed statement it rests on. We haven’t matched Mifepristone to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Mifepristone.

Overlapping uses

What Mifepristone Is Prescribed For, and What Dragon Fruit Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Mifepristone is a prescription medicine with approved uses on its FDA label. Dragon Fruit is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Mifepristone is prescribed for: Korlym is prescribed for adults with endogenous Cushing's syndrome — a condition where the body produces too much cortisol — who also have type 2 diabetes or trouble controlling blood sugar. It works to bring those blood sugar levels under control. It is only for blood sugar problems that are directly caused by Cushing's syndrome. It should not be used to treat ordinary type 2 diabetes unrelated to this condition.

Dragon Fruit has been studied for:

  • Diabetes studied, not established Dragon Fruit has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Dragon Fruit for diabetes

    A pooled analysis of three preliminary clinical studies in patients with type 2 diabetes shows that taking dragon fruit does not reduce fasting blood glucose or postprandial glucose levels when compared with no treatment. However, a sub-analysis found that dragon fruit 600 mg daily, but not 180 mg or 400 mg daily, for 4 weeks improves fasting blood glucose when compared with control.

    1 source cited
    1. 100957. Poolsup N, Suksomboon N, Paw NJ. Effect of dragon fruit on glycemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. PLoS One. 2017;12(9):e0184577. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Mifepristone on your own; if you are taking Dragon Fruit for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Mifepristone

This page covers Dragon Fruit only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Mifepristone page lists 151 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).

By severity: 8 major · 104 moderate · 39 minor.

From our pharmacist’s overview on the Mifepristone page

“Mifepristone is a drug where a failed dose has real consequences, whether it is Mifeprex used to end an early pregnancy or Korlym taken daily for Cushing's syndrome, so its interaction list deserves genuine respect. Most of the 151 ingredients on file act on the CYP3A4 enzyme that clears the drug, pushing its blood level up or dragging…”

Reviewed by 2 · Jul 18, 2026

Open the Mifepristone interaction page

One more smart check

Taking Dragon Fruit as Part of a Dietary Supplement Product? Check It for Interactions

We hold 13 real supplement products containing Dragon Fruit, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Dragon Fruit. Even though Dragon Fruit itself has no known interaction with Mifepristone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Dragon Fruit and Mifepristone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Dragon Fruit
Steady interest

#757 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Mifepristone
Top 25%

#620 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Dragon Fruit reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Dragon Fruit and Mifepristone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Dragon Fruit

What is Dragon Fruit?

  • General nutrition and antioxidant support
  • Digestive health and regularity
  • Blood sugar support
  • Heart and cholesterol health
  • Immune support

Dragon fruit is a colorful tropical fruit that is a nutritious, low-calorie source of fiber, vitamin C, and antioxidants. It is safe and healthy to eat as a food for most people, but strong human evidence that supplements or extracts treat any disease is lacking. Enjoy it as part of a balanced diet, and talk to your pharmacist before using concentrated supplements.

Hylocereus undatus · Cactaceae · Fruit (pulp and seeds); sometimes flower and peel · Fresh fruit, juice, smoothies, dried fruit, powder, capsules, and supplements

An interaction check asks whether these two react with each other — it does not ask whether Dragon Fruit is a good idea for someone in your situation. Here is what our Dragon Fruit record says about it on its own.

Dragon Fruit: dosing

There is no official or standardized dose of dragon fruit. As a food, it is simply eaten in normal serving sizes, like any other fruit.For supplements, powders, or capsules, there is no proven effective dose. If you choose to use a product, follow the directions on the label and do not exceed the recommended amount.

From our Dragon Fruit monograph — the full record covers uses, side effects and every documented interaction.

Read the full Dragon Fruit monograph & all interactions
Medication

About Mifepristone (Korlym)

What Is Mifepristone (Korlym) Used For?

Brand names: Mifeprex, Korlym

Korlym is prescribed for adults with endogenous Cushing's syndrome — a condition where the body produces too much cortisol — who also have type 2 diabetes or trouble controlling blood sugar. It works to bring those blood sugar levels under control.

It is only for blood sugar problems that are directly caused by Cushing's syndrome. It should not be used to treat ordinary type 2 diabetes unrelated to this condition.

Most-Reported Side Effects for Mifepristone

From FAERS, the FDA’s public side-effect reporting system (4,696 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Nausea 794 reports
Fatigue 695 reports
Blood potassium decreased 453 reports
Vomiting 435 reports
Dizziness 401 reports
See full Mifepristone (Korlym) drug information
Keep checking

Other Drugs & Dragon Fruit

Browse every other medication we’ve checked against Dragon Fruit — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Dragon Fruit page.

No interaction 2,743 drugs checked — show the list

We also checked Dragon Fruit against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Dragon Fruit list.

See the full Dragon Fruit interactions page
See every supplement checked against Mifepristone, ranked by severity
Evidence & sources

Dragon Fruit References

The 2 references that drive our Dragon Fruit monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Kleinheinz A, Lepp U, Hausen BM, Petersen A, Becker WM. Anaphylactic reaction to (mixed) fruit juice containing dragon fruit. J Allergy Clin Immunol. 2009 Oct;124(4):841-2. PubMed
  2. Poolsup N, Suksomboon N, Paw NJ. Effect of dragon fruit on glycemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. PLoS One. 2017;12(9):e0184577. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Dragon Fruit and Mifepristone Together: Common Questions

Is it safe to take Dragon Fruit with Mifepristone?
We do not list a known interaction between Dragon Fruit and Mifepristone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Dragon Fruit and Mifepristone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Dragon Fruit in each. That is a conversation for your prescriber, especially if Mifepristone is being adjusted to a target.
How was the Dragon Fruit and Mifepristone combination checked?
Interactions in our licensed database are recorded against drug classes. Mifepristone is filed under 4 classifications, and Dragon Fruit has documented interactions with 1 drug class — none of Mifepristone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Dragon Fruit interact with any other medications?
Yes. Dragon Fruit has 86 documented drug interactions in our database — Mifepristone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Mifepristone interact with any supplements?
Yes. Mifepristone has documented interactions with 151 supplements in our database — Dragon Fruit is not one of them. The Mifepristone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Dragon Fruit monograph Uses, safety profile, and every drug interaction in one place Mifepristone (Korlym) drug information The full plain-English guide to this medication Mifepristone supplement interactions Every supplement checked against Mifepristone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Mifepristone and Dragon Fruit?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.