Drug & supplement interaction

Elecampane + Chlorpheniramine Maleate, Dextromethorphan Hydrobromide

Chlorpheniramine Maleate, Dextromethorphan Hydrobromide brand names: Coricidin HBP Cough & Cold, Coricidin II Cough & Cold, Pediatric Vicks Formula 44m Cough & Cold Relief.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Elecampane in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elecampane safety at a glance

Elecampane overall Use caution Generally used in small amounts in tea and tinctures, but it can cause allergic reactions and stomach upset.
Pregnancy Likely Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Likely Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Elecampane? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Chlorpheniramine Maleate, Dextromethorphan Hydrobromide

Interactions in our licensed database are recorded against drug classes, not just single drug names. Chlorpheniramine Maleate, Dextromethorphan Hydrobromide is filed under 11 classifications — including cytochrome p450 2e1 (cyp2e1) substrates, cytochrome p450 2d6 (cyp2d6) inhibitors, serotonergic drugs. Elecampane has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Chlorpheniramine Maleate, Dextromethorphan Hydrobromide’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Elecampane Does Interact With Other Medications

Elecampane has 248 moderate known drug interactions in our database — Chlorpheniramine Maleate, Dextromethorphan Hydrobromide isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Chlorpheniramine Maleate, Dextromethorphan Hydrobromide)
Taking anything else?

Check Another of Your Medications Against Elecampane

Covers the 2,830 medications we’ve checked against Elecampane. Pick one to open its full report.

What to actually watch for

What Elecampane Itself Has Been Linked To

This is not an interaction — nothing below involves Chlorpheniramine Maleate, Dextromethorphan Hydrobromide. It is the side-effect record for Elecampane on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Elecampane, this list is the first place to look.

  • Diarrhea / Vomiting Additional detail

    “Orally, large doses of elecampane may cause vomiting and diarrhea (12).”

    Elecampane · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  • A skin rash Additional detail

    “Topically, elecampane can cause allergic contact dermatitis, especially in individuals sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many other herbs.”

    Elecampane · Natural Medicines adverse-effect record, reported in dermatitis.

    3 sources cited
    1. 6958. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
    2. 48729. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
    3. 48731. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Elecampane — expand a row for the licensed statement it rests on. We haven’t matched Chlorpheniramine Maleate, Dextromethorphan Hydrobromide to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Chlorpheniramine Maleate, Dextromethorphan Hydrobromide.

Special populations

Elecampane in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Chlorpheniramine Maleate, Dextromethorphan Hydrobromide

This page covers Elecampane only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Chlorpheniramine Maleate, Dextromethorphan Hydrobromide page lists 218 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Henbane (major), Lithium (major) and Scopolia (major).

By severity: 6 major · 170 moderate · 42 minor.

From our pharmacist’s overview on the Chlorpheniramine Maleate, Dextromethorphan Hydrobromide page

“Grapefruit is the interaction I would flag first for anyone taking chlorpheniramine with dextromethorphan (Coricidin HBP Cough & Cold). It blocks the enzyme that clears these ingredients, so levels and side effects can climb.”

Reviewed by 2 · Jul 18, 2026

Open the Chlorpheniramine Maleate, Dextromethorphan Hydrobromide interaction page

One more smart check

Taking Elecampane as Part of a Dietary Supplement Product? Check It for Interactions

We hold 332 real supplement products containing Elecampane, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Elecampane. Even though Elecampane itself has no known interaction with Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elecampane
Top half

#434 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Chlorpheniramine Maleate, Dextromethorphan Hydrobromide
Top 5%

#130 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elecampane reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Elecampane

What is Elecampane?

Elecampane
  • Cough and bronchitis
  • Asthma symptoms
  • Loosening mucus (expectorant)
  • Digestive upset
  • Intestinal worms (traditional)

Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Inula helenium · Asteraceae · Roots and rhizomes · Tea, tincture, dried root, capsules, lozenges, syrup

An interaction check asks whether these two react with each other — it does not ask whether Elecampane is a good idea for someone in your situation. Here is what our Elecampane record says about it on its own.

Elecampane: dosing

There is no standardized, well-established dose for elecampane. It is commonly taken as a tea made from the dried root, as a tincture, or in syrups and lozenges, with the amount varying by product and tradition.Because the strength of products varies and reliable dosing studies are lacking, the safest approach is to follow the directions on the product label and start with a small amount.

From our Elecampane monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elecampane monograph & all interactions
Keep checking

Other Drugs & Elecampane

Browse every other medication we’ve checked against Elecampane — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
248Moderate
0Minor
2,581No known interaction
248 Moderate 2,581 No interaction
Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Elecampane page.

No interaction 2,581 drugs checked — show the list

We also checked Elecampane against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Elecampane list.

See the full Elecampane interactions page
See every supplement checked against Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, ranked by severity
Evidence & sources

Elecampane References

The 5 references that drive our Elecampane monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
  4. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
  5. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide Together: Common Questions

Is it safe to take Elecampane with Chlorpheniramine Maleate, Dextromethorphan Hydrobromide?
We do not list a known interaction between Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Elecampane and Chlorpheniramine Maleate, Dextromethorphan Hydrobromide combination checked?
Interactions in our licensed database are recorded against drug classes. Chlorpheniramine Maleate, Dextromethorphan Hydrobromide is filed under 11 classifications, and Elecampane has documented interactions with 1 drug class — none of Chlorpheniramine Maleate, Dextromethorphan Hydrobromide's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Elecampane interact with any other medications?
Yes. Elecampane has 248 documented drug interactions in our database — Chlorpheniramine Maleate, Dextromethorphan Hydrobromide is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Chlorpheniramine Maleate, Dextromethorphan Hydrobromide interact with any supplements?
Yes. Chlorpheniramine Maleate, Dextromethorphan Hydrobromide has documented interactions with 218 supplements in our database — Elecampane is not one of them. The Chlorpheniramine Maleate, Dextromethorphan Hydrobromide interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Elecampane monograph Uses, safety profile, and every drug interaction in one place Chlorpheniramine Maleate, Dextromethorphan Hydrobromide supplement interactions Every supplement checked against Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Chlorpheniramine Maleate, Dextromethorphan Hydrobromide and Elecampane?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.