Drug & supplement interaction

Elecampane + Lorlatinib

Lorlatinib brand name: Lorbrena.

No Known Interaction

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated July 2026 · Pair last verified Sep 20, 2026

The bottom line No known interaction

We found no known interaction between Elecampane and Lorlatinib in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Elecampane and Lorlatinib

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Lorlatinib and Elecampane in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Elecampane safety at a glance

Elecampane overall Use caution Generally used in small amounts in tea and tinctures, but it can cause allergic reactions and stomach upset.

Pregnancy Likely Unsafe When used orally; avoid using. Read the full pregnancy detail

Breastfeeding Likely Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Lorlatinib and Elecampane? Ask Dr. Brian Staiger, PharmD, BCPS directly ›

How we checked

Why No Interaction Is Listed for Lorlatinib

Interactions in our licensed database are recorded against drug classes, not just single drug names. Lorlatinib is filed under 3 classifications — cytochrome p450 3a4 (cyp3a4) inducers, cytochrome p450 3a4 (cyp3a4) substrates, oral drugs. Elecampane has documented interactions with 1 drug class — the most serious being cns depressants (moderate) — and none of Lorlatinib’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Elecampane Does Interact With Other Medications

Elecampane has 248 moderate known drug interactions in our database — Lorlatinib isn’t one of them. If you take anything else, check it against the full list below.

Moderate 248 No known interaction 2,582 (incl. Lorlatinib)

Taking anything else?

Check Another of Your Medications Against Elecampane

Covers the 2,830 medications we’ve checked against Elecampane. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Elecampane and Lorlatinib May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

Diarrhea / Vomiting Additional detail
Elecampane
“Orally, large doses of elecampane may cause vomiting and diarrhea (12).”

Elecampane · Natural Medicines adverse-effect record, reported in diarrhea.
1 source cited

12. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Lorlatinib

Listed in the ADVERSE REACTIONS section of the FDA label for Lorlatinib. Read the label on DailyMed ›
A skin rash Additional detail
Elecampane
“Topically, elecampane can cause allergic contact dermatitis, especially in individuals sensitive to the Asteraceae/Compositae family. Members of this family include ragweed, chrysanthemums, marigolds, daisies, and many other herbs.”

Elecampane · Natural Medicines adverse-effect record, reported in dermatitis.
3 sources cited

6958. Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed

48729. Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.

48731. Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed
Lorlatinib

Listed in the ADVERSE REACTIONS section of the FDA label for Lorlatinib. Read the label on DailyMed ›

Effects for Lorlatinib come from the ADVERSE REACTIONS section of its FDA label; effects for Elecampane come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 6,977 voluntary FDA FAERS reports for Lorlatinib that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Elecampane in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Lorlatinib

This page covers Elecampane only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Lorlatinib page lists 153 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).

By severity: 3 major · 110 moderate · 40 minor.

From our pharmacist’s overview on the Lorlatinib page

“Lorlatinib (Lorbrena) treats ALK-positive lung cancer, and keeping its blood level steady is central to keeping the cancer controlled, so I treat this list with genuine vigilance. Nearly all 153 interactions on file run through CYP3A4, the enzyme that clears the drug.”

Reviewed by 2 · Jul 18, 2026

Open the Lorlatinib interaction page

One more smart check

Taking Elecampane as Part of a Dietary Supplement Product? Check It for Interactions

We hold 332 real supplement products containing Elecampane, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Elecampane. Even though Elecampane itself has no known interaction with Lorlatinib, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Elecampane and Lorlatinib Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Elecampane

Top half

#384 of 1,452 supplements looked up here in the last 7 days

29 days ago today

Medication Lorlatinib

Steady interest

#2,010 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?

Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Elecampane reference on this page ↓
Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Elecampane and Lorlatinib records this page draws on were last updated July 10, 2026.
What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.

Data structure & sourcing designed and verified by Dr. Brian Staiger, PharmD, BCPS.

Supplement

About Elecampane

What is Elecampane?

Cough and bronchitis
Asthma symptoms
Loosening mucus (expectorant)
Digestive upset
Intestinal worms (traditional)

Elecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Inula helenium · Asteraceae · Roots and rhizomes · Tea, tincture, dried root, capsules, lozenges, syrup

An interaction check asks whether these two react with each other — it does not ask whether Elecampane is a good idea for someone in your situation. Here is what our Elecampane record says about it on its own.

Elecampane: dosing

There is no standardized, well-established dose for elecampane. It is commonly taken as a tea made from the dried root, as a tincture, or in syrups and lozenges, with the amount varying by product and tradition.Because the strength of products varies and reliable dosing studies are lacking, the safest approach is to follow the directions on the product label and start with a small amount.

From our Elecampane monograph — the full record covers uses, side effects and every documented interaction.

Read the full Elecampane monograph & all interactions

Medication

About Lorlatinib

What Is Lorlatinib Used For?

Brand name: Lorbrena

Lorbrena (lorlatinib) is used to treat adults with metastatic non-small cell lung cancer (NSCLC) — meaning lung cancer that has spread — when lab testing confirms the tumor is ALK-positive (has a specific gene change that drives cancer growth). Patients must be tested with an FDA-approved diagnostic test before starting treatment.

Lorbrena has been studied in patients who have not yet received treatment for advanced disease, as well as in patients whose cancer progressed on other ALK-targeting medicines.

Most-Reported Side Effects for Lorlatinib

From FAERS, the FDA’s public side-effect reporting system (6,977 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Neoplasm progression 621 reports

Hallucination 404 reports

Weight increased 399 reports

Blood cholesterol increased 348 reports

Dyspnea 270 reports

See full Lorlatinib drug information

Keep checking

Other Drugs & Elecampane

Browse every other medication we’ve checked against Elecampane — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major

248Moderate

0Minor

2,581No known interaction

248 Moderate 2,581 No interaction

Moderate

248 interactions

Showing 60 of 248 moderate interactions — see all 248 on the Elecampane page.

No interaction 2,581 drugs checked — show the list

We also checked Elecampane against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,581 medications checked with no known interaction — see the full Elecampane list.

See the full Elecampane interactions page

See every supplement checked against Lorlatinib, ranked by severity

Evidence & sources

Elecampane References

The 5 references that drive our Elecampane monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Lamminpaa A, Estlander T, Jolanki R, Kanerva L. Occupational allergic contact dermatitis caused by decorative plants. Contact Dermatitis 1996;34:330-5. PubMed
Pazzaglia, M., Venturo, N., Borda, G., and Tosti, A. Contact dermatitis due to a massage liniment containing Inula helenium extract. Contact Dermatitis 1995;33(4):267.
Aalto-Korte, K., Alanko, K., Kuuliala, O., and Jolanki, R. Late reactions in patch tests: a 4-year review from a clinic of occupational dermatology. Contact Dermatitis 2007;56(2):81-86. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Elecampane and Lorlatinib Together: Common Questions

Is it safe to take Elecampane with Lorlatinib?

We do not list a known interaction between Elecampane and Lorlatinib. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.

Do Elecampane and Lorlatinib have any of the same side effects?

Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.

How was the Elecampane and Lorlatinib combination checked?

Interactions in our licensed database are recorded against drug classes. Lorlatinib is filed under 3 classifications, and Elecampane has documented interactions with 1 drug class — none of Lorlatinib's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.

Does Elecampane interact with any other medications?

Yes. Elecampane has 248 documented drug interactions in our database — Lorlatinib is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.

Does Lorlatinib interact with any supplements?

Yes. Lorlatinib has documented interactions with 153 supplements in our database — Elecampane is not one of them. The Lorlatinib interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Elecampane monograph Uses, safety profile, and every drug interaction in one place Lorlatinib drug information The full plain-English guide to this medication Lorlatinib supplement interactions Every supplement checked against Lorlatinib, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Lorlatinib and Elecampane?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.