Drug & supplement interaction

Glossy Privet + Hydrochlorothiazide, Spironolactone

Hydrochlorothiazide, Spironolactone brand names: Spirozine, Aldactazide, Aldactide 25, Aldactide 50.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Glossy Privet and Hydrochlorothiazide, Spironolactone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Glossy Privet and Hydrochlorothiazide, Spironolactone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydrochlorothiazide, Spironolactone and Glossy Privet in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Glossy Privet safety at a glance

Glossy Privet overall Use caution Generally used in small amounts in traditional formulas, but human safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid No reliable safety data exist, so avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydrochlorothiazide, Spironolactone and Glossy Privet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Hydrochlorothiazide, Spironolactone

Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydrochlorothiazide, Spironolactone is filed under 9 classifications — including potassium-sparing diuretics, thiazide diuretics, diuretic drugs. Glossy Privet has documented interactions with 1 drug class — the most serious being lithium (moderate) — and none of Hydrochlorothiazide, Spironolactone’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Glossy Privet Does Interact With Other Medications

Glossy Privet has 1 moderate known drug interaction in our database — Hydrochlorothiazide, Spironolactone isn’t one of them. If you take anything else, check it against the full list below.

Moderate 1 No known interaction 2,829 (incl. Hydrochlorothiazide, Spironolactone)
Taking anything else?

Check Another of Your Medications Against Glossy Privet

Covers the 2,830 medications we’ve checked against Glossy Privet. Pick one to open its full report.

What to actually watch for

What Glossy Privet Itself Has Been Linked To

This is not an interaction — nothing below involves Hydrochlorothiazide, Spironolactone. It is the side-effect record for Glossy Privet on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Glossy Privet, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    “None reported. However, respiratory allergies (allergic rhinitis, asthma) and cross-allergenicity have been reported with the pollen of other Oleaceae species including common privet (Ligustrum vulgare), olive, ash, and lilac.”

    Glossy Privet · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    2 sources cited
    1. 416. Pajaron MJ, Vila L, Prieto I, et al. Cross-reactivity of Olea europaea with other Oleaceae species in allergic rhinitis and bronchial asthma. Allergy 1997;52:829-35.
    2. 417. Batanero E, Gonzalez De La Pena MA, Villalba M, et al. Isolation, cDNA cloning and expression of Lig v 1, the major allergen from privet pollen. Clin Exp Allergy 1996;26:1401-10. DOI
  • A stuffy or runny nose Additional detail

    Recorded for Glossy Privet in the same Natural Medicines adverse-effect record shown under Wheezing above.

Everything above comes from the Natural Medicines adverse-effect record for Glossy Privet — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Hydrochlorothiazide, Spironolactone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Hydrochlorothiazide, Spironolactone column appears here.

Everything else you take

See Every Supplement That Interacts With Hydrochlorothiazide, Spironolactone

This page covers Glossy Privet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydrochlorothiazide, Spironolactone page lists 235 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Asarabacca (major) and Dolomite (major).

By severity: 10 major · 199 moderate · 26 minor.

From our pharmacist’s overview on the Hydrochlorothiazide, Spironolactone page

“Hydrochlorothiazide with spironolactone (Aldactazide) deserves genuine care around supplements, and the ten major-rated interactions on this list of 235 are the ones to understand before anything else. Most entries either add to the drug's blood-pressure-lowering effect, sometimes enough to cause dizziness or fainting, or amplify its d…”

Reviewed by 2 · Jul 18, 2026

Open the Hydrochlorothiazide, Spironolactone interaction page

One more smart check

Taking Glossy Privet as Part of a Dietary Supplement Product? Check It for Interactions

We hold 18 real supplement products containing Glossy Privet, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Glossy Privet. Even though Glossy Privet itself has no known interaction with Hydrochlorothiazide, Spironolactone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Glossy Privet and Hydrochlorothiazide, Spironolactone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Glossy Privet
Steady interest

#1,144 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Hydrochlorothiazide, Spironolactone
Top 10%

#249 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Glossy Privet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Glossy Privet and Hydrochlorothiazide, Spironolactone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Glossy Privet

What is Glossy Privet?

  • Liver and kidney support in traditional medicine
  • Immune support
  • Anti-aging and general tonic
  • Blurred vision and dizziness
  • Premature graying of hair

Glossy Privet (Ligustrum lucidum) is a fruit long used in Traditional Chinese Medicine, often combined with other herbs as a liver and kidney 'tonic.' Most of the research is from laboratory and animal studies, so its benefits in people are not well proven. Because human safety data are limited, talk to your pharmacist or doctor before using it, and avoid it during pregnancy and breastfeeding.

Ligustrum lucidum · Oleaceae · Ripe fruit (berries) · Dried fruit, decoctions (teas), powders, capsules, tinctures, and herbal formulas

An interaction check asks whether these two react with each other — it does not ask whether Glossy Privet is a good idea for someone in your situation. Here is what our Glossy Privet record says about it on its own.

Glossy Privet: dosing

There is no well-established, standardized dose of Glossy Privet for any condition. Traditional use is usually as part of a multi-herb decoction or formula prepared by a practitioner, rather than as a single supplement.Because products vary widely in strength and quality, the safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Glossy Privet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Glossy Privet monograph & all interactions
Keep checking

Other Drugs & Glossy Privet

Browse every other medication we’ve checked against Glossy Privet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
1Moderate
0Minor
2,828No known interaction
1 Moderate 2,828 No interaction
Moderate

1 interaction

No interaction 2,828 drugs checked — show the list

We also checked Glossy Privet against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,828 medications checked with no known interaction — see the full Glossy Privet list.

See the full Glossy Privet interactions page
See every supplement checked against Hydrochlorothiazide, Spironolactone, ranked by severity
Evidence & sources

Glossy Privet References

The 2 references that drive our Glossy Privet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pajaron MJ, Vila L, Prieto I, et al. Cross-reactivity of Olea europaea with other Oleaceae species in allergic rhinitis and bronchial asthma. Allergy 1997;52:829-35.
  2. Batanero E, Gonzalez De La Pena MA, Villalba M, et al. Isolation, cDNA cloning and expression of Lig v 1, the major allergen from privet pollen. Clin Exp Allergy 1996;26:1401-10. DOI

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Glossy Privet and Hydrochlorothiazide, Spironolactone Together: Common Questions

Is it safe to take Glossy Privet with Hydrochlorothiazide, Spironolactone?
We do not list a known interaction between Glossy Privet and Hydrochlorothiazide, Spironolactone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Glossy Privet and Hydrochlorothiazide, Spironolactone combination checked?
Interactions in our licensed database are recorded against drug classes. Hydrochlorothiazide, Spironolactone is filed under 9 classifications, and Glossy Privet has documented interactions with 1 drug class — none of Hydrochlorothiazide, Spironolactone's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Glossy Privet interact with any other medications?
Yes. Glossy Privet has 1 documented drug interaction in our database — Hydrochlorothiazide, Spironolactone is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Hydrochlorothiazide, Spironolactone interact with any supplements?
Yes. Hydrochlorothiazide, Spironolactone has documented interactions with 235 supplements in our database — Glossy Privet is not one of them. The Hydrochlorothiazide, Spironolactone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Glossy Privet monograph Uses, safety profile, and every drug interaction in one place Hydrochlorothiazide, Spironolactone supplement interactions Every supplement checked against Hydrochlorothiazide, Spironolactone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 2 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Hydrochlorothiazide, Spironolactone and Glossy Privet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.