Greater Celandine - Compazine (Prochlorperazine) Interaction
Herbal: Greater Celandine
Also Known As: Chelidonium majus, Bai Qu Cai, Celandine, Celidonia Mayor, Chelidonii Herba, Racine de Chélidoine, Rhizome de Chélidoine, Rhizome de la Grande Chélidoine, Schollkraut, Swallow Wort, Tetterwort, Verruguera
Drug: Prochlorperazine
Brand names:
Prochlor, Compazine
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
There were no interactions found between Prochlorperazine and Greater Celandine. This does not mean the potential for an interaction does not exist, however. There is often a lack of studies and data surrounding traditional medicine, especially concerning drug interactions, so it is important to always consult your provider before making any changes to your medication regimen.
Greater Celandine Overview
Greater celandine, also known as Chelidonium majus, is a herbaceous plant native to Europe and Asia. It is a member of the poppy family (Papaveraceae) and is known for its bright yellow flowers and shiny, sap-filled leaves.
In traditional medicine, greater celandine is believed to have a number of medicinal properties. It is thought to have antibacterial, antiviral, and anti-inflammatory effects and has been used to treat a variety of conditions, including digestive problems, respiratory infections, and skin disorders.
Greater celandine is also believed to have pain-relieving and sedative effects and has been used to treat headaches, toothaches, and other types of pain. It is sometimes used as a natural treatment for anxiety and stress, as well. Greater celandine must be used cautiously as it may have toxic effects, mainly on the liver.
Prochlorperazine Overview
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Prochlorperazine suppositories and tablets are used to control severe nausea and vomiting. Prochlorperazine tablets are also used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Prochlorperazine tablets are also used on a short-term basis to treat anxiety that could not be controlled by other medications. Prochlorperazine should not be used to treat any condition in children who are younger than 2 years old or who weigh less than 20 pounds (about 9 kilograms). Prochlorperazine is in a class of medications called conventional antipsychotics. It works by decreasing abnormal excitement in the brain.
Greater Celandine - More Interactions
Greater Celandine interacts with 592 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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Dr. Brian Staiger, PharmD
In addition to being a clinical pharmacist specializing in pharmacotherapy, Dr. Brian Staiger is a registered herbalist through the American Herbalist Guild. He has combined his passion for pharmacy practice with the study of medical ethnobotany to improve patient care. Feel free to reach out about any of your herbal or medication questions!
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