Hercules Club + Barium Sulfate
Barium Sulfate brand names: E-Z-HD, Readi-Cat 2, Readi-Cat 2 Smoothies, Varibar.
We found no known interaction between Hercules Club and Barium Sulfate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Hercules Club and Barium Sulfate
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Barium Sulfate and Hercules Club in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Hercules Club safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Barium Sulfate
Interactions in our licensed database are recorded against drug classes, not just single drug names. Barium Sulfate is filed under a single classification — oral drugs. Hercules Club has documented interactions with 3 drug classes — the most serious being antacids (minor), h2-blockers (minor) and proton pump inhibitors (ppis) (minor) — and none of Barium Sulfate’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Hercules Club Does Interact With Other Medications
Hercules Club has 36 minor known drug interactions in our database — Barium Sulfate isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Hercules Club
We haven’t checked that one against Hercules Club yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Hercules Club. Pick one to open its full report.
Hercules Club in Pregnancy & Breastfeeding
When used orally because it might have menstrual stimulant effects. There is insufficient reliable information available about the safety of the berry during pregnancy; avoid using.
When used orally because it might cause colic in nursing infants.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Barium Sulfate
This page covers Hercules Club only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Barium Sulfate page lists 17 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).
By severity: 1 major · 7 moderate · 9 minor.
From our pharmacist’s overview on the Barium Sulfate page
“Barium sulfate (Readi-Cat, Varibar, E-Z-HD) is the chalky liquid you drink so a CT scan or X-ray can see your stomach and intestines, and the 17 supplement interactions on file here deserve genuine attention before scan day. Every ingredient listed acts where barium works, in the gut.”
Reviewed by 2 · Jul 18, 2026
Where Hercules Club and Barium Sulfate Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,027 of 1,452 supplements looked up here in the last 7 days
#2,598 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Hercules Club reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 27, 2026. The Hercules Club and Barium Sulfate records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Hercules Club
What is Hercules Club?
- Toothache and mouth pain
- Indigestion and sluggish digestion
- Rheumatism and joint pain
- Circulation (as a stimulant or tonic)
- Sore throat
Hercules Club (southern prickly ash) is a traditional folk remedy used mainly for toothache, digestion, and joint pain, often by chewing the bark, which causes a tingling, numbing feeling in the mouth. Modern scientific evidence supporting these uses is very limited, and safety has not been well studied, so it is best to talk with a pharmacist or doctor before using it.
Zanthoxylum clava-herculis · Rutaceae · Bark, roots, and berries · Dried bark, tinctures, teas, and topical preparations
An interaction check asks whether these two react with each other — it does not ask whether Hercules Club is a good idea for someone in your situation. Here is what our Hercules Club record says about it on its own.
Hercules Club: dosing
There is no established standardized dose for Hercules Club. Traditional use varied widely, and product strengths differ from one brand to another.If you choose to use a commercial product, follow the directions on the label and do not exceed them.
From our Hercules Club monograph — the full record covers uses, side effects and every documented interaction.
About Barium Sulfate
What Is Barium Sulfate Used For?
Brand names: E-Z-HD, Readi-Cat 2, Readi-Cat 2 Smoothies, Varibar
Barium sulfate is used before imaging studies to help doctors see the inside of the digestive tract on X-rays and CT scans. Different branded products are approved for different procedures and patient groups.
Readi-Cat 2 and Readi-Cat 2 Smoothie flavors are used to outline the GI tract during CT scans of the abdomen. E-Z-Paque and Liquid E-Z-Paque are used for single-contrast X-ray studies of the esophagus, stomach, and small bowel. E-Z-HD is used for double-contrast X-ray studies of the esophagus, stomach, and duodenum in patients 12 and older. E-Z-Disk tablets help evaluate whether the esophagus is open (patent) in patients 12 and older. ENTERO Vu 24% is used for small bowel X-ray exams in adults. E-Z-Paste is used in single-contrast X-rays of the esophagus, pharynx, and related areas. Varibar Pudding, Varibar Honey, Varibar Nectar, Varibar Thin Honey, and Varibar Thin Liquid are used in modified barium swallow studies to assess how well a person swallows.
Most-Reported Side Effects for Barium Sulfate
From FAERS, the FDA’s public side-effect reporting system (434 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Hercules Club
Browse every other medication we’ve checked against Hercules Club — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
36 interactions
- Ranitidine ›
- Calcium Carbonate ›
- Famotidine ›
- Aluminum Hydroxide ›
- Cimetidine ›
- Omeprazole ›
- Pantoprazole ›
- Magnesium Sulfate (prescription Drug) ›
- Nizatidine ›
- Rabeprazole Sodium ›
- Dexlansoprazole ›
- Dihydroxyaluminum Sodium Carbonate ›
- Esomeprazole ›
- Esomeprazole Magnesium ›
- Esomeprazole Strontium ›
- Lansoprazole ›
- Magaldrate ›
- Rabeprazole ›
- Ranitidine Bismuth Citrate ›
- Sodium Bicarbonate (otc Drug) ›
- Aluminum Hydroxide, Magnesium Hydroxide (otc Drug) ›
- Alginic Acid, Aluminum Hydroxide ›
- Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide ›
- Aluminum Hydroxide, Aspirin, Magnesium Hydroxide ›
- Aluminum Hydroxide, Magnesium Hydroxide, Simethicone (otc Drug) ›
- Aluminum, Magnesium (otc Drug) ›
- Amoxicillin, Omeprazole Magnesium, Rifabutin ›
- Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide ›
- Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide ›
- Aspirin, Citric Acid, Sodium Bicarbonate ›
- Aspirin, Omeprazole ›
- Bismuth Subcarbonate, Calcium Carbonate, Opium ›
- Esomeprazole, Naproxen ›
- Famotidine, Ibuprofen ›
- Lansoprazole, Amoxicillin, Clarithromycin ›
- Omeprazole, Sodium Bicarbonate ›
No interaction 2,793 drugs checked — show the list
We also checked Hercules Club against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Abemaciclib ›
- Ivermectin ›
- Sertraline ›
- Testosterone ›
- Acetaminophen ›
- Losartan Potassium ›
- Aspirin ›
- Rosuvastatin ›
- Metoprolol ›
- Escitalopram ›
- Clopidogrel ›
- Rivaroxaban ›
- Atorvastatin ›
- Methamphetamine ›
- Tirzepatide ›
- Docusate ›
- Ibuprofen ›
- Warfarin Sodium ›
- Tadalafil ›
- Sumatriptan ›
- Valacyclovir ›
- Hydroxyurea ›
- Isotretinoin ›
- Prednisone ›
- Semaglutide ›
- Metformin ›
- Propranolol ›
- Lisdexamfetamine ›
- Amlodipine Besylate ›
- Amitriptyline ›
- Methotrexate ›
- Amphetamine ›
- Lisinopril ›
- Amoxicillin ›
- Bupropion ›
- Fluoxetine ›
- Bendamustine ›
- Doxycycline ›
- Pregabalin ›
- Azithromycin ›
- Lamotrigine ›
- Acyclovir ›
- Levothyroxine, Liothyronine ›
- Gabapentin ›
- Dextroamphetamine ›
- Naproxen ›
- Quetiapine ›
- Clonazepam ›
- Buspirone ›
- Duloxetine ›
- Letrozole ›
- Acetaminophen, Codeine ›
- Citalopram ›
- Methylene Blue ›
- Ciprofloxacin ›
Showing the 60 most looked-up of 2,793 medications checked with no known interaction — see the full Hercules Club list.
Hercules Club References
The 2 references that drive our Hercules Club monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Hercules Club and Barium Sulfate Together: Common Questions
Is it safe to take Hercules Club with Barium Sulfate?
How was the Hercules Club and Barium Sulfate combination checked?
Does Hercules Club interact with any other medications?
Does Barium Sulfate interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Barium Sulfate and Hercules Club?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.